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L

Leah V. Schaffer

university of california san diego

16H-index
44Paper Count
934Citation Count
Published Papers 24
Publication Date
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HIT-MAP: A scalable approach to multimodal mapping of subcellular organization
errCell Reports Methods
IF4.5
err2026-07-22
err0
errOAAI
errGege Qian; Joonwon Kim; Richa Tiwari; Benjamin J. Polacco; Antoine Forget; Leah V. Schaffer; Hark Kyun Kim; Jiahao Gao; Yuan Zhou; Gwendolyn M. Jang; Marcus R. Kelly; Xiaoyu Zhao; Helene Foussard; Liudeng Zhang; Nevan Krogan; Trey Ideker; Alejandro Chavez
errShare
errSave
A tri-modal contrastive learning framework for protein representation learning
errCell Reports Methods
IF4.5
err2026-04-15
err0
errOAAI
errLi Zhang; Han Guo; Leah Schaffer; Young Su Ko; Digvijay Singh; Hamid Rahmani; Danielle Grotjahn; Elizabeth Villa; Michael Gilson; Wei Wang; Trey Ideker; Eric Xing; Pengtao Xie
errShare
errSave
An adversarial scheme for integrating multi-modal data on protein function
errCell Systems
IF7.7
err2025-11-10
err0
PREAI
errRami Nasser; Leah V. Schaffer; Trey Ideker; Roded Sharan
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errSave
Publisher Correction: Multimodal cell maps as a foundation for structural and functional genomics
errNature
IF48.5
err2025-10-02
err0
errOAAI
errLeah V. Schaffer; Mengzhou Hu; Gege Qian; Kyung-Mee Moon; Abantika Pal; Neelesh Soni; Andrew P. Latham; Laura Pontano Vaites; Dorothy Tsai; Nicole M. Mattson; Katherine Licon; Robin Bachelder; Anthony Cesnik; Ishan Gaur; Trang Le; William Leineweber; Aji Palar; Ernst Pulido; Yue Qin; Xiaoyu Zhao; Christopher Churas; Joanna Lenkiewicz; Jing Chen; Keiichiro Ono; Dexter Pratt; Peter Zage; Ignacia Echeverria; Andrej Sali; J. Wade Harper; Steven P. Gygi; Leonard J. Foster; Edward L. Huttlin; Emma Lundberg; Trey Ideker
errShare
errSave
Multimodal cell maps as a foundation for structural and functional genomics
errNATURE
IF48.5
err2025-04-09
err0
errOAAI
errSchaffer, Leah V.; Qian, Gege; Moon, Kyung-Mee; Pal, Abantika; Latham, Andrew P.; Vaites, Laura Pontano; Tsai, Dorothy; Mattson, Nicole M.; Licon, Katherine; Bachelder, Robin; Cesnik, Anthony; Gaur, Ishan; Le, Trang; Leineweber, William; Palar, Aji; Pulido, Ernst; Qin, Yue; Zhao, Xiaoyu; Churas, Christopher; Lenkiewicz, Joanna; Chen, Jing; Ono, Keiichiro; Pratt, Dexter; Zage, Peter; Echeverria, Ignacia; Sali, Andrej; Harper, J. Wade; Gygi, Steven P.; Foster, Leonard J.; Huttlin, Edward L.
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State of the interactomes: an evaluation of molecular networks for generating biological insights
errMOLECULAR SYSTEMS BIOLOGY
IF7.7
err2024-12-09
err0
PREAI
errWright, Sarah N.; Colton, Scott; Schaffer, Leah, V; Pillich, Rudolf T.; Churas, Christopher; Pratt, Dexter; Ideker, Trey
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errSave
Mapping the Multiscale Proteomic Organization of Cellular and Disease Phenotypes
errANNUAL REVIEW OF BIOMEDICAL DATA SCIENCE
IF6
err2024-08-23
err3
errOAAI
errCesnik, Anthony; V. Schaffer, Leah; Gaur, Ishan; Jain, Mayank; Ideker, Trey; Lundberg, Emma
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errSave
Remodeling of cancer cells by chemotherapy
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errQian, Gege; Schaffer, Leah; Moon, Kyung-Mee; Foster, Leonard; Ideker, Trey; Hu, Mengzhou; Alkhairy, Sahar; Lundberg, Emma
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errSave
A global multiscale map of protein assemblies from integration of protein interactions and images
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errSchaffer, Leah V.; Hu, Mengzhou; Huttlin, Edward L.; Qian, Gege; Pal, Abantika; Soni, Neelesh; Latham, Andrew; Vaites, Laura Pontano; Trang Le; Qin, Yue; Churas, Christopher; Pratt, Dexter; Echeverria, Ignacia; Sali, Andrej; Harper, J. Wade; Gygi, Steven P.; Lundberg, Emma; Ideker, Trey
errShare
errSave
A map of osteosarcoma cell architecture reveals convergence of pediatric cancer mutations on protein assemblies
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errHu, Mengzhou; Schaffer, Leah V.; Huttlin, Edward L.; Qian, Gege; Latham, Andrew; Pal, Abantika; Vaites, Laura Pontano; Le, Trang; Qin, Yue; Churas, Christopher; Pratt, Dexter; Bachelder, Robin; Zage, Peter; Echeverria, Ignacia; Sali, Andrej; Harper, J. Wade; Gygi, Steven P.; Lundberg, Emma; Ideker, Trey
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errSave
Advanced Strategies for Proton-Transfer Reactions Coupled with Parallel Ion Parking on a 21 T FT-ICR MS for Intact Protein Analysis
errANALYTICAL CHEMISTRY
IF6.7
err2021-06-24
err15
errOAAI
errWeisbrod, Chad R.; Anderson, Lissa C.; Hendrickson, Christopher L.; Schaffer, Leah, V; Shortreed, Michael R.; Smith, Lloyd M.; Shabanowitz, Jeffrey; Hunt, Donald F.
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errSave
Mapping the multiscale structure of biological systems
errCELL SYSTEMS
IF7.7
err2021-06-01
err29
errOAAI
errSchaffer, Leah, V; Ideker, Trey
errShare
errSave
Construction of Human Proteoform Families from 21 Tesla Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Top-Down Proteomic Data
errJOURNAL OF PROTEOME RESEARCH
IF3.6
err2020-10-19
err6
errOAAI
errSchaffer, Leah, V; Anderson, Lissa C.; Butcher, David S.; Shortreed, Michael R.; Miller, Rachel M.; Pavelec, Caitlin; Smith, Lloyd M.
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errSave
Improving Proteoform Identifications in Complex Systems Through Integration of Bottom-Up and Top-Down Data
errJOURNAL OF PROTEOME RESEARCH
IF3.6
err2020-06-25
err32
errOAAI
errSchaffer, Leah, V; Millikin, Robert J.; Shortreed, Michael R.; Scalf, Mark; Smith, Lloyd M.
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errSave
Micromolded Carbon Paste Microelectrodes for Electrogenerated Chemiluminescent Detection on Microfluidic Devices
errCHEMELECTROCHEM
IF3.5
err2020-05-25
err3
errOAAI
errGross, Erin M.; Porter, Laura R.; Stark, Nicholas R.; Lowry, Emily R.; Schaffer, Leah V.; Maddipati, Sai Sujana; Hoyt, Dylan J.; Stombaugh, Sarah E.; Peila, Sarah R.; Henry, Charles S.
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errSave
Constructing Human Proteoform Families Using Intact-Mass and Top-Down Proteomics with a Multi-Protease Global Post-Translational Modification Discovery Database
errJOURNAL OF PROTEOME RESEARCH
IF3.6
err2019-09-03
err25
errOAAI
errDai, Yunxiang; Buxton, Katherine E.; Schaffer, Leah, V; Miller, Rachel M.; Millikin, Robert J.; Scalf, Mark; Frey, Brian L.; Shortreed, Michael R.; Smith, Lloyd M.
errShare
errSave
A five-level classification system for proteoform identifications
errNATURE METHODS
IF32.1
err2019-08-26
err67
errOAAI
errSmith, Lloyd M.; Thomas, Paul M.; Shortreed, Michael R.; Schaffer, Leah V.; Fellers, Ryan T.; Leduc, Richard D.; Tucholski, Trisha; Ge, Ying; Agar, Jeffrey N.; Anderson, Lissa C.; Chamot-Rooke, Julia; Gault, Joseph; Loo, Joseph A.; Pasa-Tolic, Ljiljana; Robinson, Carol V.; Schlueter, Hartmut; Tsybin, Yury O.; Vilaseca, Marta; Vizcaino, Juan Antonio; Danis, Paul O.; Kelleher, Neil L.
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errSave
Intact-Mass Analysis Facilitating the Identification of Large Human Heart Proteoforms
errANALYTICAL CHEMISTRY
IF6.7
err2019-08-08
err20
errOAAI
errSchaffer, Leah V.; Tucholski, Trisha; Shortreed, Michael R.; Ge, Ying; Smith, Lloyd M.
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errSave
Identification and Quantification of Proteoforms by Mass Spectrometry
errPROTEOMICS
IF3.9
err2019-05-15
err182
errOAAI
errSchaffer, Leah, V; Millikin, Robert J.; Miller, Rachel M.; Anderson, Lissa C.; Fellers, Ryan T.; Ge, Ying; Kelleher, Neil L.; LeDuc, Richard D.; Liu, Xiaowen; Payne, Samuel H.; Sun, Liangliang; Thomas, Paul M.; Tucholski, Trisha; Wang, Zhe; Wu, Si; Wu, Zhijie; Yu, Dahang; Shortreed, Michael R.; Smith, Lloyd M.
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errSave
Identification and Quantification of Murine Mitochondrial Proteoforms Using an Integrated Top-Down and Intact-Mass Strategy
errJOURNAL OF PROTEOME RESEARCH
IF3.6
err2018-09-05
err30
errOAAI
errSchaffer, Leah V.; Rensvold, Jarred W.; Shortreed, Michael R.; Cesnik, Anthony J.; Jochem, Adam; Scalf, Mark; Frey, Brian L.; Pagliarini, David J.; Smith, Lloyd M.
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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J. Wade Harper
H-index: 141 · Papers: 461
C
Carol V. Robinson
H-index: 132 · Papers: 818
A
Andrej Săli
H-index: 129 · Papers: 684
D
Donald F. Hunt
H-index: 120 · Papers: 527
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