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Xingxu Huang

The First Affiliated Hospital

69H-index
347Paper Count
2.3WCitation Count
Published Papers 220
Publication Date
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Improvement of precise large-fragment deletion with a versatile nuclease prime editor
errCell Discovery
IF12.5
err2026-08-14
err0
errOAAI
errXiangyang Li; Wenjun Sun; Gefei Wang; Xinpeng Ma; Mengyao Dai; Yang Zhao; Liqun Lei; Xuechao Cai; Shuaifeng Li; Shisheng Huang; Xingxu Huang; Xia Lin; Tingbo Liang
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errSave
Computation and Structure-Guided Arginine Scanning Engineers a Hyperactive AP Endonuclease for Multiplex Viral RNA Sensing
errAdvanced Science
IF14.1
err2026-07-28
err0
errOAAI
errJunlan Wang; Ting Wu; Feizuo Wang; Boyang Wang; Xin Yu Wong; Senfeng Zhang; Shengsheng Ma; Yao Liu; Fangyao Yao; Zhifeng Zeng; Siyuan Yang; Kunming Liu; Qi Wang; Yilong Wang; Yunxiang Zang; Xiaolong Wang; Xingxu Huang; Shao Li; Quanquan Ji; Tao Hu; Chunyi Hu
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errSave
Decoding SHP2 mutations by computational saturation mutagenesis
errJournal of Molecular Cell Biology
IF5.9
err2026-07-17
err0
errOAAI
errChen Wang; Xiao Tang; Qiaobin Yao; Ao Qi; Jie Zheng; Xingxu Huang; Shaolei Teng; Gaofeng Fan; null
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errSave
Guide RNA reprogramming facilitates minimized tracrRNA-dependent off-target and versatile CRISPR/Cas9 engineering
errNature Communications
IF15.7
err2026-06-17
err0
errOAAI
errWenxia Yu; Jun Chen; Junfan Guo; Fang Yu; Ge Wang; Jianxiang Lin; Xiangping Dai; Xinyi Tan; Peixiang Ma; Ligang Wu; Yu Zhang; Shisheng Huang; Pengfei Lan; Qian Bian; Xingxu Huang; Jiao Wei; Tianlin Cheng; Xiaoguo Zheng; Yunbo Qiao
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errSave
Optimization of IS621 recombinase/bridge RNA-directed recombination for precise insertion of large DNA fragments in human cells
errNature Communications
IF15.7
err2026-06-06
err0
errOAAI
errJunfan Guo; Ziguo Song; Wuke Wang; Shisheng Huang; Yu Zhang; Guanglei Li; Xingxu Huang; Xiaolong Wang; Jianghuai Liu; Lina Wu
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errSave
Uncovering functional variants using a high-efficiency PE3-based screening platform
errScience Advances
IF12.5
err2026-06-05
err0
errOAAI
errShisheng Huang; Wanyu Tao; Xiangyang Li; Junfan Guo; Yu Zhang; Guanglei Li; Pengfei Zhang; Guiquan Zhang; Gaoyang Li; Gaofeng Fan; Shang-Min Zhang; Xingxu Huang
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ANXA11 suppression restores muscular function in the mdx mouse model of Duchenne muscular dystrophy (DMD)
errNature Communications
IF15.7
err2026-05-07
err0
errOAAI
errWen Tang; Bowen Lin; Ming Jin; Tianzhen Liu; Jingyi Zhou; Yanhong Jin; Yi Chen; Yanan Zhu; Gonglu Liu; Ping Hu; Chengyong Shen; Zhuoxian Meng; Guoping Peng; Liqun Lei; Xingxu Huang; Chenxiao Zhang; Ke Chen; Guiheng Zhang; Xufeng Yang; Xue Lv; Adrien Rousseau; Jian Yang; Zhi-Ying Wu; Ge Bai; Zhen Zhong
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errSave
Causal Prediction of TP53 Variant Pathogenicity Using a Perturbation-Informed Protein Language Model
errAdvanced Science
IF14.1
err2026-04-09
err0
errOAAI
errHuiying Chen; Yang Zhao; Boqiang Hu; Wuke Wang; Minfang Song; Annabeth Xinyu Zhao; Xiangyang Li; Gefei Wang; Yanfen Wang; Weiyan Zheng; Xinpeng Zhang; Xia Lin; Yanbin Yin; Xingxu Huang; Jinfang Zheng; Tingbo Liang
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errSave
BE screen reveals METTL3 S2 dephosphorylation sensitizes gastric cancer cells to oxaliplatin by interfering METTL3-eIF3H interaction
errScience Advances
IF12.5
err2025-12-12
err0
errOAAI
errXiaoran Xu; Wanyu Tao; Yixin Liu; Tangxi Guo; Yu Zhang; Dongyi Wei; Picheng Yan; Xingxu Huang; Yongchang Wei
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errSave
Noncanonical target-strand cytosine base editing via engineered Un1Cas12f1 platform
errNature Communications
IF15.7
err2025-10-28
err0
errOAAI
errZiguo Song; Junfan Guo; Zhanqing Fan; Shuhong Huang; Guanglei Li; Zichang Zhao; Bingchun Chen; Shisheng Huang; Wenxin Zheng; Yinghui Wei; Yulin Chen; Xingxu Huang; Jianghuai Liu; Lina Wu; Xiaolong Wang
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errSave
Discovery of CRISPR-Cas12a clades using a large language model
errNature Communications
IF15.7
err2025-08-23
err0
errOAAI
errYuanyuan Feng; Junchao Shi; Zhanwei Li; Yongqian Li; Jiaxi Yang; Shisheng Huang; Jinfang Zheng; Wei Han; Yunbo Qiao; Jun Zhang; Qi Liu; Yao Yang; Chunyi Hu; Lina Wu; Xiaokang Zhang; Jin Tang; Xingxu Huang; Peixiang Ma
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errSave
Configuration of adaptable template RNA architectures to unfold the editable space of a nuclease prime editor
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-06-24
err0
PREAI
errChen, Pingbo; Li, Xiangyang; Zhou, Qian; Chen, Jingzhou; Lu, Lijin; Wang, Pei; Zhang, Guiquan; Sun, Dongxiao; Huang, Xingxu; Liu, Jianghuai; Wang, Xiaolong
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Developing safe and efficient CGBE editor based on Cas-embedding strategy
errSYNTHETIC AND SYSTEMS BIOTECHNOLOGY
IF4.4
err2025-06-01
err0
errOAAI
errLin, Tian; Wang, Xin; Zhang, Yu; Li, Guanglei; Huang, Xingxu
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errSave
Live cell quantum multiphysiology enabled by a manipulable single nanodiamond
errNATIONAL SCIENCE REVIEW
IF17.1
err2025-06-01
err2
PREAI
errXu, Yang; Yang, Yibo; Chen, Yuang; Zhu, Wenxin; Lyu, Shiyang; Zhang, Chen; Huang, Xingxu; Feng, Jiandong
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Intrinsic/proximal cell surface marker logic-gated extracellular targeted protein degradation in specific cell population
errMolecular Therapy
IF12
err2025-05-07
err0
PREAI
errYafeng Wang; Guiquan Zhang; Ping Rong; Panpan Guo; Shisheng Huang; Yang Hang; Pei Wang; Lin Tang; Xiaojing Li; Xiaojun Tang; Shuai Ding; Xingxu Huang; Jianghuai Liu; Lingyun Sun
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errSave
An engineered mitoCBE facilitates efficient mitochondrial DNA editing and modified mitochondrial transfer
errMolecular Therapy
IF12
err2025-04-03
err0
PREAI
errJie Liu; Jun Chen; Shisheng Huang; Junfan Guo; Xiangyang Li; Ying Yan; Ruijing Chen; Guanglei Li; Ming Liu; Jiao Wei; Xingxu Huang; Yunbo Qiao
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errSave
Benchmarking copy number aberrations inference tools using single-cell multi-omics datasets
errBRIEFINGS IN BIOINFORMATICS
IF7.7
err2025-03-04
err0
errOAAI
errSong, Minfang; Ma, Shuai; Wang, Gong; Wang, Yukun; Yang, Zhenzhen; Xie, Bin; Guo, Tongkun; Huang, Xingxu; Zhang, Liye
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errSave
Loss of SGK1 supports metastatic colonization in hepatocellular carcinoma by promoting resistance to T cell-mediated immunity
errJournal of Hepatology
IF33
err2025-01-30
err0
PREAI
errZefan Zhang; Chenlu Geng; Minfang Song; Hengbin Liang; Kaiqian Zhou; Yang Liu; Jing Wu; Xingxu Huang; Jian Zhou; Jia Fan; David H. Peng; Liye Zhang; Yong Cang; Yunfan Sun
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Intelligent Design of Lipid Nanoparticles for Enhanced Gene Therapeutics
errMOLECULAR PHARMACEUTICS
IF4.5
err2025-01-29
err0
PREAI
errYuan, Yichen; Li, Ying; Li, Guo; Lei, Liqun; Huang, Xingxu; Yao, Yuan
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errSave
METTL16 and YTHDC1 Regulate Spermatogonial Differentiation via m6A
errCELL PROLIFERATION
IF5.6
err2024-11-29
err0
errOAAI
errGu, Xueying; Dai, Xinyuan; Sun, Haifeng; Lian, Yilong; Huang, Xingxu; Shen, Bin; Zhang, Pengfei
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errSave

Research Directions

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Co-authors
Cooperation Journals
M
Mark J. Smyth
H-index: 172 · Papers: 1.4K
C
Chuan He
H-index: 161 · Papers: 978
L
Lei Zhang
H-index: 145 · Papers: 1.7K
梁
梁兴杰 (Xing‐Jie Liang)
H-index: 110 · Papers: 647
陈
陈虹宇 (Hongyu Chen)
H-index: 106 · Papers: 1.6K
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