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Y

Yunshun Chen

Walter and Eliza Hall Institute of Medical Research

28H-index
77Paper Count
1.9WCitation Count
Published Papers 33
Publication Date
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Multiscale analysis and functional validation of the cellular and genetic determinants of skeletal disease
errNature Genetics
IF29
err2026-07-10
err0
errOAAI
errRyan C. Chai; Mischa Lundberg; Bernard Freudenthal; James T. Smith; Andrew P. Boughton; Yuandan Zhang; Kaitlyn A. Flynn; Monika Frysz; Alexander P. Corr; Weng Hua Khoo; Davide Komla-Ebri; Michael R. G. Dack; Siobhan E. Guilfoyle; John G. Logan; Natalie C. Butterfield; Victoria D. Leitch; Andrea S. Pollard; Riikka E. Mäkitie; Nathaniel Bradford; Lorenzo Ramos-Mucci; Amaia Vilas-Zornoza; Yunshun Chen; Raymond K. H. Yip; Jeremy Er; Siew Zhuan Tan; Michelle M. McDonald; Scott E. Youlten; C. Marcelo Sergio; Ariel Castro-Martinez; Shelley G. Young; Elena Skorokhodova; David M. Evans; Joseph E. Powell; Christiaan A. de Leeuw; Adam D. Ewing; John A. Eisman; Robert D. Blank; Tri Giang Phan; Anne K. Lagendijk; Edwin D. Hawkins; Horng Lii Oh; Rebecca E. McIntyre; Edith M. Hessel; Jake P. Taylor-King; Paul A. Baldock; Emma L. Duncan; Graham R. Williams; J. H. Duncan Bassett; Peter I. Croucher; John P. Kemp
errShare
errSave
Dividing out quantification uncertainty enables assessment of differential transcript usage with limma and edgeR
errNUCLEIC ACIDS RESEARCH
IF13.1
err2025-12-11
err0
PREAI
errBaldoni, Pedro L.; Chen, Lizhong; Li, Mengbo; Chen, Yunshun; Smyth, Gordon K.
errShare
errSave
stPipe: a flexible and streamlined R/Bioconductor pipeline for preprocessing sequencing-based spatial transcriptomics data
errNAR GENOMICS AND BIOINFORMATICS
IF2.8
err2025-12-01
err0
errOAAI
errXu, Yang; Sargeant, Callum J.; You, Yue; You, Yupei; Su, Shian; Wang, Changqing; Tian, Luyi; Chen, Yunshun; Ritchie, Matthew E.
errShare
errSave
Incorporating exon–exon junction reads enhances differential splicing detection
errBMC Bioinformatics
IF3.3
err2025-08-25
err0
PREAI
errMai T. Pham; Michael J. G. Milevskiy; Jane E. Visvader; Yunshun Chen
errShare
errSave
Profiling the spatial architecture of multiple myeloma in human bone marrow trephine biopsy specimens with spatial transcriptomics
errBlood
IF23.1
err2025-07-14
err0
errOAAI
errRaymond K. H. Yip; Jeremy Er; Lei Qin; Quoc Hoang Nguyen; Allan Motyer; Joel S. Rimes; Amanda Light; Ruvimbo D. Mishi; Ling Ling; Casey J. A. Anttila; Ellen Tsui; Daniela Amann-Zalcenstein; Mark R. Dowling; Kelly L. Rogers; Rory Bowden; Yunshun Chen; Simon J. Harrison; Edwin D. Hawkins
errShare
errSave
Circulating immune cells exhibit distinct traits linked to metastatic burden in breast cancer
errBREAST CANCER RESEARCH
IF5.6
err2025-05-08
err0
errOAAI
errMangiola, S.; Brown, R.; Zhan, C.; Berthelet, J.; Guleria, S.; Liyanage, C.; Ostrouska, S.; Wilcox, J.; Merdas, M.; Fuge-Larsen, P.; Bell, C.; Schroder, J.; Mielke, L. A.; Mariadason, J. M.; Tsao, S. Chang-Hao; Chen, Y.; Yadav, V. K.; Vodala, S.; Anderson, R. L.; Merino, D.; Behren, A.; Yeo, B.; Papenfuss, A. T.; Pal, B.
errShare
errSave
Benchmarking spatial transcriptomics technologies with the multi-sample SpatialBenchVisium dataset
errGENOME BIOLOGY
IF9.4
err2025-03-28
err1
errOAAI
errDu, Mei R. M.; Wang, Changqing; Law, Charity W.; Amann-Zalcenstein, Daniela; Anttila, Casey J. A.; Ling, Ling; Hickey, Peter F.; Sargeant, Callum J.; Chen, Yunshun; Ioannidis, Lisa J.; Rajasekhar, Pradeep; Yip, Raymond K. H.; Rogers, Kelly L.; Hansen, Diana S.; Bowden, Rory; Ritchie, Matthew E.
errShare
errSave
MCL-1 safeguards activated hair follicle stem cells to enable adult hair regeneration
errNATURE COMMUNICATIONS
IF15.7
err2025-03-22
err1
errOAAI
errChin, Hui San; Cheng, Jinming; Hsu, Shih Han; Lum, Guo Guang; Zaldivia, Maria T. K.; Nelameham, Sarmilla; Guo, Fusheng; Mallavarapu, Keerthana; Jackling, Felicity C.; Yang, Jicheng; Tan, Jonathan S. L.; Sampath, Prabha; Barker, Nick; Smyth, Gordon K.; Lindeman, Geoffrey J.; Strasser, Andreas; Visvader, Jane E.; Chen, Yunshun; Chen, Ting; Fu, Nai Yang
errShare
errSave
Hormone-responsive progenitors have a unique identity and exhibit high motility during mammary morphogenesis
errCELL REPORTS
IF6.9
err2024-12-01
err0
errOAAI
errDawson, Caleb A.; Milevskiy, Michael J. G.; Capaldo, Bianca D.; Yip, Raymond K. H.; Song, Xiaoyu; Vaillant, Francois; Prokopuk, Lexie; Jackling, Felicity C.; Smyth, Gordon K.; Chen, Yunshun; Lindeman, Geoffrey J.; Visvader, Jane E.
errShare
errSave
Single-cell transcriptional atlas of human breast cancers and model systems
errCLINICAL AND TRANSLATIONAL MEDICINE
IF6.8
err2024-10-17
err0
errOAAI
errAltman, Julia E.; Olex, Amy L.; Zboril, Emily K.; Walker, Carson J.; Boyd, David C.; Myrick, Rachel K.; Hairr, Nicole S.; Koblinski, Jennifer E.; Puchalapalli, Madhavi; Hu, Bin; Dozmorov, Mikhail G.; Chen, X. Steven; Chen, Yunshun; Perou, Charles M.; Lehmann, Brian D.; Visvader, Jane E.; Harrell, J. Chuck
errShare
errSave
Ehf controls mammary alveolar lineage differentiation and is a putative suppressor of breast tumorigenesis
errDEVELOPMENTAL CELL
IF8.7
err2024-08-01
err0
errOAAI
errNightingale, Rebecca; Reehorst, Camilla M.; Vukelic, Natalia; Papadopoulos, Nikolaos; Liao, Yang; Guleria, Shalini; Bell, Caroline; Vaillant, Francois; Paul, Sudip; Luk, Ian Y.; Dhillon, Amardeep S.; Jenkins, Laura J.; Morrow, Riley J.; Jackling, Felicity C.; Chand, Ashwini L.; Chisanga, David; Chen, Yunshun; Williams, David S.; Anderson, Robin L.; Ellis, Sarah; Meikle, Peter J.; Shi, Wei; Visvader, Jane E.; Pal, Bhupinder; Mariadason, John M.
errShare
errSave
Decoding breast cancer: Unraveling subtype and model differences through multi-model single-cell RNA sequencing data integration
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errAltman, Julia E.; Walker, Carson J.; Zboril, Emily K.; Hairr, Nicole S.; Myrick, Rachel K.; Boyd, David C.; Koblenski, Jennifer E.; Puchalapalli, Madhavi; Hu, Bin; Dozmorov, Mikhail G.; Chen, Xi; Chen, Yunshun; Perou, Charles M.; Lehmann, Brian D.; Visvader, Jane E.; Olex, Amy L.; Harrell, J. Chuck
errShare
errSave
Identification of aberrant luminal progenitors and mTORC1 as a potential breast cancer prevention target in BRCA2 mutation carriers
errNATURE CELL BIOLOGY
IF19.1
err2024-01-12
err8
PREAI
errJoyce, Rachel; Pascual, Rosa; Heitink, Luuk; Capaldo, Bianca D.; Vaillant, Francois; Christie, Michael; Tsai, Minhsuang; Surgenor, Elliot; Anttila, Casey J. A.; Rajasekhar, Pradeep; Jackling, Felicity C.; Trussart, Marie; Milevskiy, Michael J. G.; Song, Xiaoyu; Li, Mengbo; Teh, Charis E.; Gray, Daniel H. D.; Smyth, Gordon K.; Chen, Yunshun; Lindeman, Geoffrey J.; Visvader, Jane E.
errShare
errSave
Dividing out quantification uncertainty allows efficient assessment of differential transcript expression with edgeR
errNUCLEIC ACIDS RESEARCH
IF13.1
err2023-12-07
err4
errOAAI
errBaldoni, Pedro L.; Chen, Yunshun; Hediyeh-zadeh, Soroor; Liao, Yang; Dong, Xueyi; Ritchie, Matthew E.; Shi, Wei; Smyth, Gordon K.
errShare
errSave
Three-dimensional genome architecture coordinates key regulators of lineage specification in mammary epithelial cells
errCELL GENOMICS
IF9
err2023-11-01
err1
errOAAI
errMilevskiy, Michael J. G.; Coughlan, Hannah D.; Kane, Serena R.; Johanson, Timothy M.; Kordafshari, Somayeh; Chan, Wing Fuk; Tsai, Minhsuang; Surgenor, Elliot; Wilcox, Stephen; Allan, Rhys S.; Chen, Yunshun; Lindeman, Geoffrey J.; Smyth, Gordon K.; Visvader, Jane E.
errShare
errSave
Benchmarking long-read RNA-sequencing analysis tools using in silico mixtures
errNATURE METHODS
IF32.1
err2023-10-02
err19
errOAAI
errDong, Xueyi; Du, Mei R. M.; Gouil, Quentin; Tian, Luyi; Jabbari, Jafar S.; Bowden, Rory; Baldoni, Pedro L.; Chen, Yunshun; Smyth, Gordon K.; Amarasinghe, Shanika L.; Law, Charity W.; Ritchie, Matthew E.
errShare
errSave
Activation of stably silenced genes by recruitment of a synthetic de-methylating module
errNATURE COMMUNICATIONS
IF15.7
err2022-09-23
err12
errOAAI
errChan, Wing Fuk; Coughlan, Hannah D.; Chen, Yunshun; Keenan, Christine R.; Smyth, Gordon K.; Perkins, Andrew C.; Johanson, Timothy M.; Allan, Rhys S.
errShare
errSave
Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death
errCELL DEATH AND DIFFERENTIATION
IF15.4
err2022-03-31
err10
errOAAI
errEl-Saafin, Farrah; Bergamasco, Maria, I; Chen, Yunshun; May, Rose E.; Esakky, Prabagaran; Hediyeh-zadeh, Soroor; Dixon, Mathew; Wilcox, Stephen; Davis, Melissa J.; Strasser, Andreas; Smyth, Gordon K.; Thomas, Tim; Voss, Anne K.
errShare
errSave
In vivo genome-editing screen identifies tumor suppressor genes that cooperate with Trp53 loss during mammary tumorigenesis
errMOLECULAR ONCOLOGY
IF4.5
err2022-01-26
err8
errOAAI
errHeitink, Luuk; Whittle, James R.; Vaillant, Francois; Capaldo, Bianca D.; Dekkers, Johanna F.; Dawson, Caleb A.; Milevskiy, Michael J. G.; Surgenor, Elliot; Tsai, Minhsuang; Chen, Huei-Rong; Christie, Michael; Chen, Yunshun; Smyth, Gordon K.; Herold, Marco J.; Strasser, Andreas; Lindeman, Geoffrey J.; Visvader, Jane E.
errShare
errSave
Mammary tumour cells remodel the bone marrow vascular microenvironment to support metastasis
errNATURE COMMUNICATIONS
IF15.7
err2021-11-26
err58
errOAAI
errYip, Raymond K. H.; Rimes, Joel S.; Capaldo, Bianca D.; Vaillant, Francois; Mouchemore, Kellie A.; Pal, Bhupinder; Chen, Yunshun; Surgenor, Elliot; Murphy, Andrew J.; Anderson, Robin L.; Smyth, Gordon K.; Lindeman, Geoffrey J.; Hawkins, Edwin D.; Visvader, Jane E.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
C
Charles M. Perou
H-index: 193 · Papers: 2.0K
A
Andreas Strasser
H-index: 135 · Papers: 815
C
Charles R. Mackay
H-index: 120 · Papers: 418
D
David M. Evans
H-index: 118 · Papers: 727
G
Gordon K. Smyth
H-index: 113 · Papers: 594
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