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SaveMechanistic safety assessment via multi-omic characterisation of systemic pathway perturbations following in vivo MAT2A inhibition
Fogal, Valentina; Michopoulos, Filippos; Jarnuczak, Andrew F.; Hamza, Ghaith M.; Harlfinger, Stephanie; Davey, Paul; Hulme, Heather; Atkinson, Stephen J.; Gabrowski, Piotr; Cheung, Tony; Grondine, Michael; Hoover, Clare; Rose, Jonathan; Bray, Chandler; Foster, Alison J.; Askin, Sean; Majumder, Muntasir Mamun; Fitzpatrick, Paul; Miele, Eric; Macdonald, Ruth; Keun, Hector C.; Coen, Muireann Share Save Integrative dynamic MultiOMICs analysis identifies cell cycle and DNA damage response phenotypes as downstream consequences of using the PRMT5 inhibitor AZD3470Hong, Ted; Criscione, Steven; Jarnuczak, Andrew; Urosevic, Jelena; Ashenden, Stephanie; Hamza, Ghaith; Kumar, Praveen; Cvetesic, Nevena; Bradshaw, Lauren; Moore, Shaun; Karl, Daniel; Zhang, Tianhui; Sousa, Abel; Cairns, Jonathan; Iannetta, Anthony; Zhang, Andrew; Miele, Eric; Reicha, John; Chambers, Chris; Elgendy, Ramy; Lindgren, Julia; Jachimowicz, Daniel; Clausen, Maryam; Belfield, Graham; Cheung, Tony; Grondine, Michael; Lynch, James T.; Chan, Ho Man; Critchlow, Susan; Dean, Emma Share Save Proteomic evaluation of combination data in acute myeloid leukemia to inform mechanism of action and new targetsChan, Lori; Ozen, Zuleyha; Iannetta, Anthony; Miele, Eric; Kar, Funda; Jarnuczak, Andrew; Nelson, Geoff; Markovets, Aleksandra; Roderick-Richardson, Justine; Urosevic, Jelena; Drew, Lisa; Mettetal, Jerome Share Save Proprotein convertase PCSK9 affects expression of key surface proteins in human pancreatic beta cells via intracellular and extracellular regulatory circuitsSaitoski, Kevin; Ryaboshapkina, Maria; Hamza, Ghaith M.; Jarnuczak, Andrew F.; Berthault, Claire; Carlotti, Francoise; Armanet, Mathieu; Sengupta, Kaushik; Underwood, Christina Rye; Andersson, Shalini; Guillas, Isabelle; Le Goff, Wilfried; Scharfmann, Raphael Share Save Characterization of the Secretome, Transcriptome, and Proteome of Human β Cell Line EndoC-βH1Ryaboshapkina, Maria; Saitoski, Kevin; Hamza, Ghaith M.; Jarnuczak, Andrew F.; Pechberty, Severine; Berthault, Claire; Sengupta, Kaushik; Underwood, Christina Rye; Andersson, Shalini; Scharfmann, Raphael Share Save Using Deep Learning to Extrapolate Protein Expression MeasurementsBarzine, Mitra Parissa; Freivalds, Karlis; Wright, James C.; Opmanis, Martins; Rituma, Darta; Ghavidel, Fatemeh Zamanzad; Jarnuczak, Andrew F.; Celms, Edgars; Cerans, Karlis; Jonassen, Inge; Lace, Lelde; Antonio Vizcaino, Juan; Choudhary, Jyoti Sharma; Brazma, Alvis; Viksna, Juris Share Save The functional landscape of the human phosphoproteomeOchoa, David; Jarnuczak, Andrew F.; Vieitez, Cristina; Gehre, Maja; Soucheray, Margaret; Mateus, Andre; Kleefeldt, Askar A.; Hill, Anthony; Garcia-Alonso, Luz; Stein, Frank; Krogan, Nevan J.; Savitski, Mikhail M.; Swaney, Danielle L.; Vizcaino, Juan A.; Noh, Kyung-Min; Beltrao, Pedro Share Save The ProteomeXchange consortium in 2020: enabling 'big data' approaches in proteomicsDeutsch, Eric W.; Bandeira, Nuno; Sharma, Vagisha; Perez-Riverol, Yasset; Carver, Jeremy J.; Kundu, Deepti J.; Garcia-Seisdedos, David; Jarnuczak, Andrew F.; Hewapathirana, Suresh; Pullman, Benjamin S.; Wertz, Julie; Sun, Zhi; Kawano, Shin; Okuda, Shujiro; Watanabe, Yu; Hermjakob, Henning; MacLean, Brendan; MacCoss, Michael J.; Zhu, Yunping; Ishihama, Yasushi; Vizcaino, Juan A. Share Save Expression Atlas update: from tissues to single cellsPapatheodorou, Irene; Moreno, Pablo; Manning, Jonathan; Fuentes, Alfonso Munoz-Pomer; George, Nancy; Fexova, Silvie; Fonseca, Nuno A.; Fullgrabe, Anja; Green, Matthew; Huang, Ni; Huerta, Laura; Lqbal, Haider; Jianu, Monica; Mohammed, Suhaib; Zhao, Lingyun; Jarnuczak, Andrew F.; Jupp, Simon; Marioni, John; Meyer, Kerstin; Petryszak, Robert; Medina, Cesar Augusto Prada; Talavera-Lopez, Carlos; Teichmann, Sarah; Vizcaino, Juan Antonio; Brazma, Alvis Share Save Quantifying the impact of public omics dataPerez-Riverol, Yasset; Zorin, Andrey; Dass, Gaurhari; Manh-Tu Vu; Xu, Pan; Glont, Mihai; Vizcaino, Juan Antonio; Jarnuczak, Andrew F.; Petryszak, Robert; Ping, Peipei; Hermjakob, Henning Share Save The PRIDE database and related tools and resources in 2019: improving support for quantification dataPerez-Riverol, Yasset; Csordas, Attila; Bai, Jingwen; Bernal-Llinares, Manuel; Hewapathirana, Suresh; Kundu, Deepti J.; Inuganti, Avinash; Griss, Johannes; Mayer, Gerhard; Eisenacher, Martin; Perez, Enrique; Uszkoreit, Julian; Pfeuffer, Julianus; Sachsenberg, Timo; Yilmaz, Sule; Tiwary, Shivani; Cox, Juergen; Audain, Enrique; Walzer, Mathias; Jarnuczak, Andrew F.; Ternent, Tobias; Brazma, Alvis; Vizcaino, Juan Antonio Share Save Share Save Expression Atlas: gene and protein expression across multiple studies and organismsPapatheodorou, Irene; Fonseca, Nuno A.; Keays, Maria; Tang, Y. Amy; Barrera, Elisabet; Bazant, Wojciech; Burke, Melissa; Fullgrabe, Anja; Fuentes, Alfonso Munoz-Pomer; George, Nancy; Huerta, Laura; Koskinen, Satu; Mohammed, Suhaib; Geniza, Matthew; Preece, Justin; Jaiswal, Pankaj; Jarnuczak, Andrew F.; Huber, Wolfgang; Stegle, Oliver; Vizcaino, Juan Antonio; Brazma, Alvis; Petryszak, Robert Share Save The ProteomeXchange consortium in 2017: supporting the cultural change in proteomics public data depositionDeutsch, Eric W.; Csordas, Attila; Sun, Zhi; Jarnuczak, Andrew; Perez-Riverol, Yasset; Ternent, Tobias; Campbell, David S.; Bernal-Llinares, Manuel; Okuda, Shujiro; Kawano, Shin; Moritz, Robert L.; Carver, Jeremy J.; Wang, Mingxun; Ishihama, Yasushi; Bandeira, Nuno; Hermjakob, Henning; Vizcaino, Juan Antonio Share Save Share Save 
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