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J

John W. Barrett

western university

42H-index
207Paper Count
7.1KCitation Count
Published Papers 87
Publication Date
Understanding and overcoming innate and acquired MAPK inhibition resistance in anaplastic thyroid cancer
err2026-05-15
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errOAAI
errPeter Y.F. Zeng; Jalna Meens; Amir Hossein Karimi; Harrison Pan; Matthew J. Cecchini; Laura Jarycki; Sarah B. Ryan; Alice E. Dawson; Mushfiq H. Shaikh; David A. Palma; Eric Winquist; Lakshman Gunaratnam; Joe S. Mymryk; John W. Barrett; Paul C. Boutros; Laurie Ailles; Anthony C. Nichols
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NOTCH1 loss promotes chemo and radio-resistance in head and neck cancer
err2025-12-08
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PREAI
errMushfiq H. Shaikh; Walid Gazala; Cindy Zeng; Mahdi Farzad Naimi; Matthew Cecchini; Amir Karimi; Halema Khan; Krista Joris; Shengjie Ying; Harrison Pan; Mohd Wessam Al Jawhri; David A. Palma; Joe S. Mymryk; Peter YF. Zeng; John W. Barrett; Anthony C. Nichols
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Oncological and functional outcomes of salvage surgery for local oropharyngeal cancer recurrence after primary Radiation±Chemotherapy
err2025-09-01
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PREAI
errLaxague, Francisco; Fnais, Naif; Zabihi, Dorsa; Fung, Kevin; MacNeil, Danielle; Mendez, Adrian; Yoo, John; Lang, Pencilla; Mymryk, Joe S.; Barrett, John W.; Palma, David A.; Nichols, Anthony C.
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Molecular features of T and N stage progression in laryngeal cancer
err2025-06-01
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errOAAI
errLi, Nicholas; Zeng, Peter Y. F.; Kim, Hugh A. J.; Karimi, Amir; Ying, Shengjie; Shaikh, Mushfiq H.; Khan, Halema; Joris, Krista; Al Jawhri, Mohdwessam; Cecchini, Matthew; Mymryk, Joe S.; Barrett, John W.; Nichols, Anthony C.
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Cohort-level clinical trajectory and molecular landscape of idiopathic subglottic stenosis for precision laryngology-a study of the Canadian airways research (CARE) group
err2025-04-01
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errOAAI
errJun Lin, R.; Zeng, Peter YF.; Fung, Kevin; Khan, Halema; Cecchini, Matthew J.; Woo, Elissa; Hu, Amanda; Anderson, Jennifer; Macinnis, Patrick; Karimi, Amir; Ying, Shengjie; Al Jawhri, Mohdwessam; Lin, Sherman; Jarycki, Laura; Shaikh, Mushfiq H.; Pan, Harrison; Coburn, Bryan; Mymryk, Joe S.; Inculet, Richard; Barrett, John W.; Nichles, Anthony C.; Canadian Soc Otolaryngol Collaborat Res Initiat
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Loss of MACROD2 drives radioresistance but not cisplatin resistance in HPV-positive head and neck cancer
err2024-12-01
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errOAAI
errDawson, Alice; Karimi, Amir Hossein; Shaikh, Mushfiq H.; Gazala, Walid; Zeng, Peter Y. F.; Ryan, Sarah E. B.; Pan, Harrison; Khan, Halema; Cecchini, Matthew; Mendez, Adrian; Palma, David A.; Mymryk, Joe S.; Barrett, John W.; Nichols, Anthony C.
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Core Modifications of GSK3335103 toward Orally Bioavailable αvβ6 Inhibitors with Improved Synthetic Tractability
err2024-10-17
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PREAI
errHryczanek, Heather F.; Barrett, John; Barrett, Tim N.; Burley, Glenn A.; Cookson, Rosa E.; Hatley, Richard J. D.; Measom, Nicholas D.; Roper, James A.; Rowedder, James E.; Slack, Robert J.; Smieja, Connor B.; Macdonald, Simon J. F.
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Discovery and Development of Highly Potent and Orally Bioavailable Nonpeptidic αvβ6 Integrin Inhibitors
err2024-09-13
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PREAI
errProcopiou, Panayiotis A.; Barrett, John; Crawford, Matthew H. J.; Hatley, Richard J. D.; Hancock, Ashley P.; Pritchard, John M.; Rowedder, James E.; Copley, Royston C. B.; Slack, Robert J.; Sollis, Steven L.; Thorp, Lee R.; Lippa, Rhys A.; Macdonald, Simon J. F.; Barrett, Tim N.
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Understanding and overcoming innate and acquired resistance to type I and II RAF inhibitors in anaplastic thyroid cancer using translational functional genomics
err2024-03-22
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PREAI
errZeng, Peter; Meens, Jalna; Barrett, John; Cecchini, Matthew J.; Ryan, Sarah B.; Pan, Nachuan; Karimi, Amir; Jarycki, Laura; Dawson, Alice E.; Shaikh, Mushfiq; Palma, David; Winquist, Eric; Boutros, Paul C.; Ailles, Laurie; Nichols, Anthony C.
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The role of TIM3 and PD1 blockades in head and neck cancer
err2024-03-22
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PREAI
errShaikh, Mushfiq; Karimi, Amir; Zeng, Peter; Pan, Harrison; Barrett, John; Nichols, Anthony
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The genomic and evolutionary landscapes of anaplastic thyroid carcinoma
err2024-03-01
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errOAAI
errZeng, Peter Y. F.; Prokopec, Stephenie D.; Lai, Stephen Y.; Pinto, Nicole; Chan-Seng-Yue, Michelle A.; Clifton-Bligh, Roderick; Williams, Michelle D.; Howlett, Christopher J.; Plantinga, Paul; Cecchini, Matthew J.; Lam, Alfred K.; Siddiqui, Iram; Wang, Jianxin; Sun, Ren X.; Watson, John D.; Korah, Reju; Carling, Tobias; Agrawal, Nishant; Cipriani, Nicole; Ball, Douglas; Nelkin, Barry; Rooper, Lisa M.; Bishop, Justin A.; Garnis, Cathie; Berean, Ken; Nicolson, Norman G.; Weinberger, Paul; Henderson, Ying C.; Lalansingh, Christopher M.; Tian, Mao; Yamaguchi, Takafumi N.; Livingstone, Julie; Salcedo, Adriana; Patel, Krupal; Vizeacoumar, Frederick; Datti, Alessandro; Xi, Liu; Nikiforov, Yuri E.; Smallridge, Robert; Copland, John A.; Marlow, Laura A.; Hyrcza, Martin D.; Delbridge, Leigh; Sidhu, Stan; Sywak, Mark; Robinson, Bruce; Fung, Kevin; Ghasemi, Farhad; Kwan, Keith; MacNeil, S. Danielle; Mendez, Adrian; Palma, David A.; Khan, Mohammed I.; Shaikh, Mushfiq; Ruicci, Kara M.; Wehrli, Bret; Winquist, Eric; Yoo, John; Mymryk, Joe S.; Rocco, James W.; Wheeler, David; Scherer, Steve; Giordano, Thomas J.; Barrett, John W.; Faquin, William C.; Gill, Anthony J.; Clayman, Gary; Boutros, Paul C.; Nichols, Anthony C.
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HPV16 Intratypic Variants in Head and Neck Cancers: A North American Perspective
err2023-12-12
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errOAAI
errGameiro, Steven F.; Salnikov, Mikhail Y.; Zeng, Peter Y. F.; Barrett, John W.; Nichols, Anthony C.; Mymryk, Joe S.
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Loss of LRP1B expression drives acquired chemo and radio-resistance in HPV-positive head and neck cancer
err2023-11-01
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errOAAI
errShaikh, Mushfiq H.; Dawson, Alice; Prokopec, Stephenie D.; Barrett, John W.; Zeng, Peter Y. F.; Khan, Mohammed I.; Ryan, Sarah E. B.; Cecchini, Matthew; Palma, David A.; Mymryk, Joe S.; Boutros, Paul C.; Nichols, Anthony C.
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The HPV Induced Cancer Resource (THInCR): a Suite of Tools for Investigating HPV-Dependent Human Carcinogenesis
errMSPHERE
IF3.1
err2022-08-31
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errOAAI
errSalnikov, Mikhail; Gameiro, Steven F.; Zeng, Peter Y. F.; Barrett, John W.; Nichols, Anthony C.; Mymryk, Joe S.
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Proteome and phosphoproteome signatures of recurrence for HPV+ head and neck squamous cell carcinoma
err2022-07-30
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errOAAI
errKaneko, Tomonori; Zeng, Peter Y. F.; Liu, Xuguang; Abdo, Rober; Barrett, John W. W.; Zhang, Qi; Nichols, Anthony C. C.; Li, Shawn Shun-Cheng
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The Impact of Surgical Resectability on Outcomes for Patients Undergoing Primary Radiation Treatment for Human Papillomavirus-Related Oropharyngeal Cancer
err2022-07-01
err9
PREAI
errFnais, Naif; Laxague, Francisco; Alzahrani, Faisal; Fung, Kevin; Di Gravio, Eric; MacNeil, Danielle; Mendez, Adrian; Yoo, John; Lang, Pencilla; Mymryk, Joe S.; Barrett, John W.; Tay, Keng Yow; Leung, Andrew; Nichols, Anthony C.; Palma, David A.
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Pharmacological characterisation of GSK3335103, an oral αvβ6 integrin small molecule RGD-mimetic inhibitor for the treatment of fibrotic disease
err2021-12-01
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PREAI
errWilkinson, Alex L.; John, Alison E.; Barrett, John W.; Gower, E.; Morrison, Valerie S.; Man, Yim; Pun, K. Tao; Roper, James A.; Luckett, Jeni C.; Borthwick, Lee A.; Barksby, Ben S.; Burgoyne, Rachel A.; Barnes, Rory; Fisher, Andrew J.; Procopiou, Panayiotis A.; Hatley, Richard J. D.; Barrett, Tim N.; Marshall, Richard P.; Macdonald, Simon J. F.; Jenkins, R. Gisli; Slack, Robert J.
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All HPV-negative head and neck cancers are not the same: Analysis of the TCGA dataset reveals that anatomical sites have distinct mutation, transcriptome, hypoxia, and tumor microenvironment profiles
err2021-05-01
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PREAI
errKim, Hugh Andrew Jinwook; Zeng, Peter Y. F.; Shaikh, Mushfiq Hassan; Mundi, Neil; Ghasemi, Farhad; Di Gravio, Eric; Khan, Halema; MacNeil, Danielle; Khan, Mohammed Imran; Patel, Krupal; Mendez, Adrian; Yoo, John; Fung, Kevin; Lang, Pencilla; Palma, David A.; Mymryk, Joe S.; Barrett, John W.; Boutros, Paul C.; Nichols, Anthony C.
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Low expression of NSD1, NSD2, and NSD3 define a subset of human papillomavirus-positive oral squamous carcinomas with unfavorable prognosis
err2021-02-15
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errOAAI
errGameiro, Steven F.; Ghasemi, Farhad; Zeng, Peter Y. F.; Mundi, Neil; Howlett, Christopher J.; Plantinga, Paul; Barrett, John W.; Nichols, Anthony C.; Mymryk, Joe S.
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Discovery of the first potent and selective αvβ5 integrin inhibitor based on an amide-containing core
err2020-12-01
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errOAAI
errLippa, Rhys A.; Barrett, John; Pal, Sandeep; Rowedder, James E.; Murphy, John A.; Barrett, Tim N.
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