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D

David B. Ascher

university of queensland

61H-index
333Paper Count
2.0WCitation Count
Published Papers 134
Publication Date
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Tracking breast cancer progression using Methylscape
errScience Advances
IF12.5
err2026-08-28
err0
errOAAI
errZhen Zhang; Emtiaz Ahmed; Nicolas Constantin; Jennifer Lu; Stephanie Portelli; David B. Ascher; Darren Korbie; Alain Wuethrich; Abu Ali Ibn Sina; Matt Trau
errShare
errSave
Transformers as a substrate for structural biology
errCurrent Opinion in Structural Biology
IF7
err2026-02-06
err0
PREAI
errAshar J. Malik; Stephanie Portelli; David B. Ascher
errShare
errSave
mCSM-metal: A Deep Learning Resource to Predict Effect of Mutations on Metal Ion Binding
errJournal of Molecular Biology
IF4.5
err2026-02-05
err0
PREAI
errAkshita Kumar; Ashar J. Malik; David B. Ascher
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errSave
Systematic evaluation of computational tools to predict the effects of mutations on protein-ligand binding affinity in the absence of experimental structures
errBriefings in Bioinformatics
IF7.7
err2026-02-05
err0
errOAAI
errQisheng Pan; Stephanie Portelli; Thanh Binh Nguyen; David B Ascher
errShare
errSave
Structome-AlignViewer: On Confidence Assessment in Structure-Aware Alignments
errGenome Biology and Evolution
IF2.8
err2026-01-01
err0
PREAI
errMalik, Ashar J.; Mao, Siying; Hugenholtz, Philip; Ascher, David B.
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errSave
Exploring a genetic basis for the metabolic perturbations in ME/CFS using UK biobank
erriScience
IF4.1
err2025-12-03
err0
errOAAI
errKatherine Huang; Muhammad Muneeb; Natalie Thomas; Elena K. Schneider-Futschik; Paul R. Gooley; David B. Ascher; Christopher W. Armstrong
errShare
errSave
kinCSM-RTK: Machine Learning-Based Screening of Receptor Tyrosine Kinase Inhibitors in Drug Discovery
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2025-12-01
err0
PREAI
errSerghini, Adam; Zhou, Yunzhuo; Myung, Yoochan; de Sa, Alex G. C.; Portelli, Stephanie; Ascher, David B.
errShare
errSave
Combinatorial Discovery of RAFT Cationic Polymers for mRNA Delivery: Structure–Function Insights from High-Throughput Screening and Machine Learning
errBiomacromolecules
IF5.4
err2025-10-07
err0
PREAI
errWenting Yang; Shangqian Li; Siqi Yu; Alex G. C. de Sá; Tanmayee Sai Sivani Ita; Tian Liang; Helen Forgham; Ruirui Qiao; Jiulong Li; Patrick S. Stayton; David B. Ascher; Huan Meng; Andrew K. Whittaker; Changkui Fu
errShare
errSave
Haploinsufficient variants in SMAD5 are associated with isolated congenital heart disease
errHuman Genetics and Genomics Advances
IF3.6
err2025-07-05
err0
errOAAI
errDimuthu Alankarage; Iryna Leshchynska; Stephanie Portelli; Alena Sipka; Gillian M. Blue; Victoria O’Reilly; Debjani Das; Emma M. Rath; Annabelle Enriquez; Michael Troup; Miriam Fine; Nicola Poplawski; Maxim Verlee; David T. Humphreys; Richard P. Harvey; Gavin Chapman; Edwin P. Kirk; David S. Winlaw; Bert Callewaert; Wendy K. Chung; David Ascher; Eleni Giannoulatou; Sally L. Dunwoodie
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errSave
Proximity proteomics reveals a mechanism of fatty acid transfer at lipid droplet-mitochondria- endoplasmic reticulum contact sites
errNATURE COMMUNICATIONS
IF15.7
err2025-03-03
err0
errOAAI
errBezawork-Geleta, Ayenachew; Devereux, Camille J.; Keenan, Stacey N.; Lou, Jieqiong; Cho, Ellie; Nie, Shuai; De Souza, David P.; Narayana, Vinod K.; Siddall, Nicole A.; Rodrigues, Carlos H. M.; Portelli, Stephanie; Zheng, Tenghao; Nim, Hieu T.; Ramialison, Mirana; Hime, Gary R.; Dodd, Garron T.; Hinde, Elizabeth; Ascher, David B.; Stroud, David A.
errShare
errSave
Assessing the predicted impact of single amino acid substitutions in MAPK proteins for CAGI6 challenges
errHUMAN GENETICS
IF3.6
err2025-02-20
err0
PREAI
errTurina, Paola; Petrosino, Maria; Enriquez Sandoval, Carlos A.; Novak, Leonore; Pasquo, Alessandra; Alexov, Emil; Alladin, Muttaqi Ahmad; Ascher, David B.; Babbi, Giulia; Bakolitsa, Constantina; Casadio, Rita; Cheng, Jianlin; Fariselli, Piero; Folkman, Lukas; Kamandula, Akash; Katsonis, Panagiotis; Li, Minghui; Li, Dong; Lichtarge, Olivier; Mahmud, Sajid; Martelli, Pier Luigi; Pal, Debnath; Panday, Shailesh Kumar; Pires, Douglas E. V.; Portelli, Stephanie; Pucci, Fabrizio; Rodrigues, Carlos H. M.; Rooman, Marianne; Savojardo, Castrense; Schwersensky, Martin; Shen, Yang; Strokach, Alexey V.; Sun, Yuanfei; Woo, Junwoo; Radivojac, Predrag; Brenner, Steven E.; Chiaraluce, Roberta; Consalvi, Valerio; Capriotti, Emidio
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errSave
Drug resistance-associated mutations in Plasmodium UBP-1 disrupt its essential deubiquitinating activity
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2025-02-01
err0
errOAAI
errSmith, Cameron J.; Eavis, Heledd; Briggs, Carla; Henrici, Ryan; Karpiyevich, Maryia; Ansbro, Megan R.; Hoshizaki, Johanna; van Noort, Gerbrand J. van der Heden; Ascher, David B.; Sutherland, Colin J.; Lee, Marcus C. S.; Artavanis-Tsakonas, Katerina
errShare
errSave
Assessing the predicted impact of single amino acid substitutions in calmodulin for CAGI6 challenges
errHUMAN GENETICS
IF3.6
err2024-12-23
err0
PREAI
errTurina, Paola; Dal Cortivo, Giuditta; Sandoval, Carlos A. Enriquez; Alexov, Emil; Ascher, David B.; Babbi, Giulia; Bakolitsa, Constantina; Casadio, Rita; Fariselli, Piero; Folkman, Lukas; Kamandula, Akash; Katsonis, Panagiotis; Li, Dong; Lichtarge, Olivier; Martelli, Pier Luigi; Panday, Shailesh Kumar; Pires, Douglas E. V.; Portelli, Stephanie; Pucci, Fabrizio; Rodrigues, Carlos H. M.; Rooman, Marianne; Savojardo, Castrense; Schwersensky, Martin; Shen, Yang; Strokach, Alexey V.; Sun, Yuanfei; Woo, Junwoo; Radivojac, Predrag; Brenner, Steven E.; Dell'Orco, Daniele; Capriotti, Emidio
errShare
errSave
Discriminating Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and comorbid conditions using metabolomics in UK Biobank
errCOMMUNICATIONS MEDICINE
IF6.3
err2024-11-26
err1
errOAAI
errHuang, Katherine; de Sa, Alex G. C.; Thomas, Natalie; Phair, Robert D.; Gooley, Paul R.; Ascher, David B.; Armstrong, Christopher W.
errShare
errSave
A new method for network bioinformatics identifies novel drug targets for mucinous ovarian carcinoma
errgenomics proteomics bioinformatics
IF2.8
err2024-08-24
err1
errOAAI
errCraig, Olivia; Lee, Samuel; Pilcher, Courtney; Saoud, Rita; Abdirahman, Suad; Salazar, Carolina; Williams, Nathan; Ascher, David B.; Vary, Robert; Luu, Jennii; Cowley, Karla J.; Ramm, Susanne; Li, Mark Xiang; Thio, Niko; Li, Jason; Semple, Tim; Simpson, Kaylene J.; Gorringe, Kylie L.; Holien, Jessica K.
errShare
errSave
piscesCSM: prediction of anticancer synergistic drug combinations
errJOURNAL OF CHEMINFORMATICS
IF5.7
err2024-07-19
err1
errOAAI
errAlJarf, Raghad; Rodrigues, Carlos H. M.; Myung, Yoochan; Pires, Douglas E. V.; Ascher, David B.
errShare
errSave
DDMut-PPI: predicting effects of mutations on protein-protein interactions using graph-based deep learning
errNUCLEIC ACIDS RESEARCH
IF13.1
err2024-05-23
err3
errOAAI
errZhou, Yunzhuo; Myung, Yoochan; Rodrigues, Carlos H. M.; Ascher, David B.
errShare
errSave
Targeting the Plasmodium falciparum UCHL3 ubiquitin hydrolase using chemically constrained peptides
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-05-13
err2
errOAAI
errKing, Harry R.; Bycroft, Mark; Nguyen, Thanh-Binh; Kelly, Geoff; Vinogradov, Alexander A.; Rowling, Pamela J. E.; Stott, Katherine; Ascher, David B.; Suga, Hiroaki; Itzhaki, Laura S.; Artavanis -Tsakonas, Katerina
errShare
errSave
Joint genotypic and phenotypic outcome modeling improves base editing variant effect quantification
errNATURE GENETICS
IF31.8
err2024-04-24
err2
PREAI
errRyu, Jayoung; Barkal, Sam; Yu, Tian; Jankowiak, Martin; Zhou, Yunzhuo; Francoeur, Matthew; Phan, Quang Vinh; Li, Zhijian; Tognon, Manuel; Brown, Lara; Love, Michael I.; Bhat, Vineel; Lettre, Guillaume; Ascher, David B.; Cassa, Christopher A.; Sherwood, Richard I.; Pinello, Luca
errShare
errSave
Deep-PK: deep learning for small molecule pharmacokinetic and toxicity prediction
errNUCLEIC ACIDS RESEARCH
IF13.1
err2024-04-18
err20
errOAAI
errMyung, Yoochan; de Sa, Alex G. C.; Ascher, David B.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
M
Matthew A. Brown
H-index: 144 · Papers: 1.4K
J
Jeremy Farrar
H-index: 141 · Papers: 772
I
Ingrid E. Scheffer
H-index: 141 · Papers: 1.0K
T
Thomas H. Marwick
H-index: 136 · Papers: 2.1K
J
Janet M. Thornton
H-index: 135 · Papers: 784
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