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J

Jeffrey S. Hyams

connecticut children's medical center

83H-index
721Paper Count
3.3WCitation Count
Published Papers 161
Publication Date
Metabolomics predict treatment response to vedolizumab in pediatric IBD: results from the prospective VedoKids cohort study
err2026-08-07
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PREAI
errRicardo G Suarez, PhD; Ori Bar Or, MD; Esther Orlanski-Meyer, MD; Zivia Shavit, MSc; Asaf Azulay, MSc; Efrat Broide, MD; Darja Urlep, MD; Art Kastl, MD; Jeffrey S Hyams, MD; Jeremiah Levine, MD; Joel Rosh, MD; Richard K Russell, PhD; Dan Turner, MD, PhD; Eytan Wine, MD, PhD
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Efficacy and safety of mirikizumab in paediatric participants with moderately-to-severely active ulcerative colitis (SHINE-1): a multicentre, open-label, non-randomised phase 2 trial
err2025-11-19
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PREAI
errJess L Kaplan; Athos Bousvaros; Dan Turner; Marla Dubinsky; Amy Larkin; Jordan Johns; Yuki Otani; Wallace Crandall; Wendy J Komocsar; Jeffrey S Hyams
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Model-Informed Deep Q-Networks to Guide Infliximab Dosing in Pediatric Crohn’s Disease
err2025-11-05
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errOAAI
errKei Irie; Phillip Minar; Jack Reifenberg; Brendan M. Boyle; Joshua D. Noe; Jeffrey S. Hyams; Tomoyuki Mizuno
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Short Ileal Microvillus Length Phenotype Associates with Progression from Inflammatory to Complicated Disease Behavior in Pediatric Crohn's Disease
err2025-11-01
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PREAI
errHaberman, Yael; Braun, Tzipi; Karns, Rebekah; Bartel, Courtney A.; Bonkowski, Erin; Simpson, Katherine F.; Walters, Thomas D.; Hyams, Jeffrey S.; Liu, Ta-Chiang; Kugathasan, Subra; Denson, Lee A.; VanDussen, Kelli L.
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Hybrid Population Pharmacokinetic–Machine Learning Modeling to Predict Infliximab Pharmacokinetics in Pediatric and Young Adult Patients with Crohn’s Disease
err2025-08-30
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errOAAI
errKei Irie; Phillip Minar; Jack Reifenberg; Brendan M. Boyle; Joshua D. Noe; Jeffrey S. Hyams; Tomoyuki Mizuno
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AN EVALUATION OF ENDOSCOPIC HEALING IN PEDIATRIC CROHN'S DISEASE USING MULTIPLE ENDOSCOPIC SCORING METHODS IDENTIFIES SIMILARITIES IN BLOOD AND STOOL BIOMARKERS
err2025-02-28
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PREAI
errBartel, Courtney; Mizuno, Tomoyuki; Irie, Kei; Samuels, Abigail; Lynch, Kimberly; Jackson, Kimberly; Hyams, Jeffrey; Boyle, Brendan; Saeed, Shehzad; Kurowski, Jacob; Noe, Joshua; Chun, Kelly; Yang, Jane; Denson, Lee; Minar, Phillip
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Long term maintenance treatment with vedolizumab in pediatric IBD: a three-year follow-up of the prospective multicenter VEDOKIDS study
err2025-01-22
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PREAI
errAtia, O.; Shavit-Brunschwig, Z.; Orlanski-Meyer, E.; Stein, R.; Efrat, B.; Hyams, J.; Granot, M.; Rosh, J.; Hussey, S.; Markowitz, J.; Russell, R. K.; Turner, D.
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Identification of Arginine-Vasopressin Receptor 1a (Avpr1a/Avpr1a) Avpr1a ) as a Novel Candidate Gene for Chronic Visceral Pain Sheds Light on the Potential Role of Enteric Neurons in the Development of Visceral Hypersensitivity
err2024-09-01
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errOAAI
errKader, Leena; Willits, Adam B.; Meriano, Sebastian; Christianson, Julie A.; La, Jun-Ho; Feng, Bin; Knight, Brittany; Kosova, Gulum; Deberry, Jennifer J.; Coates, Matthew D.; Hyams, Jeffrey S.; Baumbauer, Kyle M.; Young, Erin E.
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Environmental Factors Associated With Risk of Crohn's Disease Development in the Crohn's and Colitis Canada - Genetic, Environmental, Microbial Project
err2024-09-01
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PREAI
errXue, Mingyue; Leibovitzh, Haim; Shao, Jingcheng; Neustaeter, Anna; Dong, Mei; Xu, Wei; Espin-Garcia, Osvaldo; Griffiths, Anne M.; Steinhart, A. Hillary; Turner, Dan; Huynh, Hien Q.; Dieleman, Levinus A.; Panaccione, Remo; Aumais, Guy; Bressler, Brian; Bitton, Alain; Murthy, Sanjay; Marshall, John K.; Hyams, Jeffrey S.; Otley, Anthony; Bernstein, Charles N.; Moayyedi, Paul; El-Matary, Wael; Fich, Alexander; Denson, Lee A.; Ropeleski, Mark J.; Abreu, Maria T.; Deslandres, Colette; Cino, Maria; Avni-Biron, Irit; Lee, Sun-Ho; Turpin, Williams; Croitoru, Kenneth
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Efficacy and safety of linaclotide in treating functional constipation in paediatric patients: a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial
err2024-03-01
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PREAI
errDi Lorenzo, Carlo; Khlevner, Julie; Rodriguez-Araujo, Gerardo; Xie, Wangang; Huh, Susanna Y.; Ando, Masakazu; Hyams, Jeffrey S.; Nurko, Samuel; Benninga, Marc A.; Simon, Michael; Hewson, Marcella E.; Saps, Miguel
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Outcomes in Adult Inflammatory Bowel Disease Clinical Trials: Assessment of Similarity Among Participants with Adolescent-onset and Adult-onset Disease
err2024-02-26
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PREAI
errRosh, Joel R.; Turner, Dan; Hyams, Jeffrey S.; Dubinsky, Marla; Griffiths, Anne M.; Cohen, Stanley A.; Hung Lo, Kim; Kim, Lilianne; Volger, Sheri; Zhang, Renping; Strauss, Richard; Conklin, Laurie S.
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Progression of Pediatric Crohn's Disease Is Associated With Anti-Tumor Necrosis Factor Timing and Body Mass Index Z-Score Normalization
err2024-02-01
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PREAI
errGeem, Duke; Hercules, David; Pelia, Ranjit S.; Venkateswaran, Suresh; Griffiths, Anne; Noe, Joshua D.; Dotson, Jennifer L.; Snapper, Scott; Rabizadeh, Shervin; Rosh, Joel R.; Baldassano, Robert N.; Markowitz, James F.; Walters, Thomas D.; Ananthakrishnan, Ashwin; Sharma, Garima; Denson, Lee A.; Hyams, Jeffrey S.; Kugathasan, Subra
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Managing pediatric Crohn's disease: recent insights
err2023-10-20
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PREAI
errBaldwin, Katherine; Grossi, Victoria; Hyams, Jeffrey S.
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Gut Microbiome Composition Is Associated With Future Onset of Crohn's Disease in Healthy First-Degree Relatives
err2023-09-01
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errOAAI
errGaray, Juan Antonio Raygoza; Turpin, Williams; Lee, Sun-Ho; Smith, Michelle I.; Goethel, Ashleigh; Griffiths, Anne M.; Moayyedi, Paul; Espin-Garcia, Osvaldo; Abreu, Maria; Aumais, Guy L.; Bernstein, Charles N.; Biron, Irit A.; Cino, Maria; Deslandres, Colette; Dotan, Iris; El-Matary, Wael; Feagan, Brian; Guttman, David S.; Huynh, Hien; Dieleman, Levinus A.; Hyams, Jeffrey S.; Jacobson, Kevan; Mack, David; Marshall, John K.; Otley, Anthony; Panaccione, Remo; Ropeleski, Mark; Silverberg, Mark S.; Steinhart, A. Hillary; Turner, Dan; Yerushalmi, Baruch; Paterson, Andrew D.; Croitoru, Kenneth; Xu, W.
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Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn's disease, and celiac disease
err2023-07-24
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errOAAI
errBraun, Tzipi; Sosnovski, Katya E.; Amir, Amnon; BenShoshan, Marina; VanDussen, Kelli L.; Karns, Rebekah; Levhar, Nina; Abbas-Egbariya, Haya; Hadar, Rotem; Efroni, Gilat; Castel, David; Avivi, Camila; Rosen, Michael J.; Grifiths, Anne M.; Walters, Thomas D.; Mack, David R.; Boyle, Brendan M.; Ali, Syed Asad; Moore, Sean R.; Schirmer, Melanie; Xavier, Ramnik J.; Kugathasan, Subra; Jegga, Anil G.; Weiss, Batya; Mayer, Chen; Barshack, Iris; Ben-Horin, Shomron; Ulitsky, Igor; Beucher, Anthony; Ferrer, Jorge; Hyams, Jeffrey S.; Denson, Lee A.; Haberman, Yael
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GATA6-AS1 Regulates Intestinal Epithelial Mitochondrial Functions, and its Reduced Expression is Linked to Intestinal Inflammation and Less Favourable Disease Course in Ulcerative Colitis
err2023-06-16
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errOAAI
errSosnovski, Katya E.; Braun, Tzipi; Amir, Amnon; Moshel, Danielle; BenShoshan, Marina; VanDussen, Kelli L.; Levhar, Nina; Abbas-Egbariya, Haya; Beider, Katia; Ben-Yishay, Rakefet; Ali, Syed Asad; Moore, Sean R.; Kugathasan, Subra; Abramovich, Ifat; Saar, Efrat Glick; Weiss, Batya; Barshack, Iris; Gottlieb, Eyal; Geiger, Tamar; Ben-Horin, Shomron; Ulitsky, Igor; Hyams, Jeffrey S.; Denson, Lee A.; Haberman, Yael
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Multicenter Cohort Study of Infliximab Pharmacokinetics and Therapy Response in Pediatric Acute Severe Ulcerative Colitis
err2023-05-01
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errOAAI
errWhaley, Kaitlin G.; Xiong, Ye; Karns, Rebekah; Hyams, Jeffrey S.; Kugathasan, Subra; Boyle, Brendan M.; Walters, Thomas D.; Kelsen, Judith; LeLeiko, Neal; Shapiro, Jason; Waddell, Amanda; Fox, Sejal; Bezold, Ramona; Bruns, Stephanie; Widing, Robin; Haberman, Yael; Collins, Margaret H.; Mizuno, Tomoyuki; Minar, Phillip; D'Haens, Geert R.; Denson, Lee A.; Vinks, Alexander A.; Rosen, Michael J.
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Development and Validation of the TUMMY-UC: A Patient-Reported Outcome for Pediatric Ulcerative Colitis
err2023-04-01
err5
PREAI
errMarcovitch, Liron; Focht, Gili; Carmon, Natalie; Tersigni, Claudia; Ledder, Oren; Lev-Traion, Raffi; Chruch, Peter C.; Hyams, Jeffrey S.; Baldassano, Robert N.; Bousvaros, Athos; Mack, David R.; Hussey, Seamus; Otley, Anthony; Croft, Nicholas M.; Kapplemen, Michael D.; Griffiths, Anne M.; Turner, Dan
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Longitudinal DNA methylation profiling of the rectal mucosa identifies cell-specific signatures of disease status, severity and clinical outcomes in ulcerative colitis cell-specific DNA methylation signatures of UC
err2023-03-24
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errOAAI
errVenkateswaran, Suresh; Somineni, Hari K. K.; Matthews, Jason D. D.; Kilaru, Varun; Hyams, Jeffrey S. S.; Denson, Lee A. A.; Kellamayer, Richard; Gibson, Greg; Cutler, David J. J.; Conneely, Karen N. N.; Smith, Alicia K. K.; Kugathasan, Subra
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Outcomes, dosing, and predictors of vedolizumab treatment in children with inflammatory bowel disease (VEDOKIDS): a prospective, multicentre cohort study
err2023-01-01
err31
PREAI
errAtia, Ohad; Shavit-Brunschwig, Zivia; Mould, Diane R.; Stein, Ronen; Matar, Manar; Aloi, Marina; Ledder, Oren; Focht, Gili; Urlep, Darja; Hyams, Jeffrey; Broide, Efrat; Weiss, Batia; Levine, Jeremiah; Russell, Richard K.; Turner, Dan
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