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Sylvia E. Escher

Fraunhofer Institute for Toxicology and Experimental Medicine

26H-index
148Paper Count
2.7KCitation Count
Published Papers 62
Publication Date
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The in vitro alkaline comet assay with liver models as a complementary tool for genotoxicity assessment of N-nitrosamines
errArchives of Toxicology
IF6.9
err2026-06-02
err0
errOAAI
errM. A. Djuari; A. Londenberg; A. Bassan; K. Cross; L. Elenschneider; S. E. Escher; J. Fahrer; J. Fangmann; C. Felske; R. Frötschl; B. Haas; G. E. Johnson; M. Vogel; R. Whomsley; C. Ziemann
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errSave
Retrospective analysis of clinical laboratory parameters in Han Wistar rat controls
errFrontiers in Toxicology
IF4.6
err2025-12-03
err0
errOAAI
errRupert Kellner; Alexander Amberg; Frank Bringezu; Dragomir Ivanov Draganov; Annika Kreuchwig; Wolfgang Muster; Guillemette Duchateau-Nguyen; Nils Oberhauser; Paolo Piraino; Markus Schaefer; Nelly Simetska; Thomas Steger-Hartmann; Sylvia E. Escher
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Report on the European Partnership for Alternative Approaches to Animal Testing (EPAA) “New Approach Methodology (NAMs) User Forum”, 30 – 31 October 2024, Helsinki, Finland
errRegulatory Toxicology and Pharmacology
IF3.5
err2025-10-24
err0
errOAAI
errMark T.D. Cronin; Sophie Cable; Christian Desaintes; Sylvia E. Escher; Ellen Hessel; Ellen Fritsche; Petra Kern; Gavin Maxwell; Gladys Ouedraogo; Tomasz Sobanski; Matthias Wehr; Andrew White
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A Unified Whole Lung PBK Model for Inhalational Uptake of Gases and Aerosols in Men
errCPT: Pharmacometrics & Systems Pharmacology
IF0
err2025-10-04
err0
errOAAI
errNorman Nowak; Sylvia E. Escher; Katharina Schwarz
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errSave
Feasibility study on integrating morphological and transcriptomic data for identifying teratogenic molecular markers in zebrafish embryo toxicity testing
errCOMPUTATIONAL TOXICOLOGY
IF2.9
err2025-06-01
err0
PREAI
errWehr, Matthias M.; Witters, Hilda; Remy, Silvie; Schultz, Bruce; Jacobs, Marc; Escher, Sylvia E.
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errSave
Quantitative Investigation of Nitrosamine Drug Substance-Related Impurities (NDSRIs) Under Artificial Gastric Conditions by Liquid Chromatography-Tandem Mass Spectrometry and Structure-Activity Relationship Analysis
erranalysis and testing
IF2.7
err2025-03-12
err1
errOAAI
errMatthias Vogel; Sylvia E. Escher; Emanuel Weiler; Anke Londenberg; Uwe Deppenmeier; Rhys Whomsley
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errSave
Report on the European Partnership for Alternative Approaches to Animal Testing (EPAA) New Approach Methodologies (NAMs) User Forum Kick-Off Workshop
errREGULATORY TOXICOLOGY AND PHARMACOLOGY
IF3.5
err2025-02-01
err0
errOAAI
errCronin, Mark T. D.; Baltazar, Maria T.; Barton-Maclaren, Tara S.; Bercaru, Ofelia; De Abrew, K. Nadira; Desaintes, Christian; Escher, Sylvia E.; Kern, Petra; Maxwell, Gavin; Rogiers, Vera; Schutte, Katrin; Sobanski, Tomasz
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errSave
Animal-free Safety Assessment of Chemicals: Project Cluster for Implementation of Novel Strategies (ASPIS) definition of new approach methodologies
errENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
IF2.8
err2025-01-29
err0
errOAAI
errColbourne, John K.; Escher, Sylvia E.; Lee, Robert; Vinken, Mathieu; van de Water, Bob; Freedman, Jonathan H.
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errSave
The Long Way from Raw Data to NAM-Based Information: Overview on Data Layers and Processing Steps
errALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION
IF5.8
err2025-01-01
err3
errOAAI
errBlum, J; Brüll, M; Hengstler, JG; Dietrich, DR; Gruber, AJ; Dipalo, M; Kraushaar, U; Mangas, I; Terron, A; Fritsche, E; Marx-Stoelting, P; Hardy, B; Schepky, A; Escher, SE; Hartung, T; Landsiedel, R; Odermatt, A; Sachana, M; Koch, K; Dönmez, A; Masjosthusmann, S; Bothe, K; Schildknecht, S; Beilmann, M; Beltman, JB; Fitzpatrick, S; Mangerich, A; Rehm, M; Tangianu, S; Zickgraf, FM; Kamp, H; Burger, G; van de Water, B; Kleinstreuer, N; White, A; Leist, M
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errSave
Informing the decision-making process for potential PMT/vPvM chemicals through the adoption of a risk-based prioritization framework: the ZeroPM approach
errENVIRONMENTAL SCIENCES EUROPE
IF6
err2024-12-18
err0
errOAAI
errGouin, Todd; Bitsch, Annette; van Duursen, Majorie; Escher, Sylvia E.; Hamers, Timo
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errSave
Assessment of pulmonary fibrosis using weighted gene co-expression network analysis
errFRONTIERS IN TOXICOLOGY
IF4.6
err2024-10-24
err0
errOAAI
errDrake, Christina; Zobl, Walter; Escher, Sylvia E.
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errSave
Profiling the endocrine-disrupting properties of triazines, triazoles, and short-chain PFAS
errTOXICOLOGICAL SCIENCES
IF4.1
err2024-10-04
err0
PREAI
errCarlier, Maxim P.; Cenijn, Peter H.; Baygildiev, Timur; Irwan, Jenny; Escher, Sylvia E.; van Duursen, Majorie B. M.; Hamers, Timo
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errSave
A comparison of the TempO-Seq and Affymetrix microarray platform using RTqPCR validation
errBMC GENOMICS
IF3.7
err2024-07-03
err1
errOAAI
errWehr, Matthias M.; Reamon-Buettner, Stella Marie; Ritter, Detlef; Knebel, Jan; Niehof, Monika; Escher, Sylvia E.
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errSave
Uncovering the toxicity mechanisms of a series of carboxylic acids in liver cells through computational and experimental approaches
errTOXICOLOGY
IF4.6
err2024-05-01
err1
errOAAI
errOrtega-Vallbona, Rita; Mendez, Rebeca; Tolosa, Laia; Escher, Sylvia E.; Castell, Jose, V; Gozalbes, Rafael; Serrano-Candelas, Eva
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errSave
Update of the Cancer Potency Database (CPDB) to enable derivations of Thresholds of Toxicological Concern (TTC) for cancer potency
errFOOD AND CHEMICAL TOXICOLOGY
IF3.5
err2023-12-01
err1
errOAAI
errYang, Chihae; Rathman, James F.; Ribeiro, J. Vinicius; Batke, Monika; Escher, Sylvia E.; Firman, James W.; Hobocienski, Bryan; Kellner, Rupert; Mostrag, Aleksandra; Przybylak, Katarzyna R.; Cronin, Mark T. D.
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errSave
Exposure considerations in human safety assessment: Report from an EPAA Partners' Forum
errREGULATORY TOXICOLOGY AND PHARMACOLOGY
IF3.5
err2023-10-01
err4
errOAAI
errCronin, Mark T. D.; Ball, Nicholas; Beken, Sonja; Bender, Hans; Bercaru, Ofelia; Caneva, Laura; Corvaro, Marco; Currie, Richard A.; Dawson, Jeffrey L.; Desert, Paul; Escher, Sylvia E.; Franco, Antonio; Irizar, Amaia; Mehta, Jyotigna M.; Rogiers, Vera; Tremblay, Raphae T.; Westmoreland, Carl; Maxwell, Gavin
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Workshop report: Challenges faced in developing inhalation thresholds of Toxicological Concern (TTC)-State of the science and next steps
errREGULATORY TOXICOLOGY AND PHARMACOLOGY
IF3.5
err2023-08-01
err1
errOAAI
errBowden, Anthony M.; Escher, Sylvia E.; Rose, Jane; Sadekar, Nikaeta; Patlewicz, Grace; O'Keeffe, Lara; Bury, Dagmar; Hewitt, Nicola J.; Giusti, Arianna; Rothe, Helga
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Substantiate a read-across hypothesis by using transcriptome data-A case study on volatile diketones
errFRONTIERS IN TOXICOLOGY
IF4.6
err2023-05-03
err3
errOAAI
errDrake, Christina; Wehr, Matthias M. M.; Zobl, Walter; Koschmann, Jeannette; De Lucca, David; Kuehne, Britta A.; Hansen, Tanja; Knebel, Jan; Ritter, Detlef; Boei, Jan; Vrieling, Harry; Bitsch, Annette; Escher, Sylvia E. E.
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errSave
Protectiveness of NAM-Based Hazard Assessment - Which Testing Scope is Required?
errALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION
IF5.8
err2023-01-01
err4
errOAAI
errZobl, Walter; Bitsch, Annette; Blum, Jonathan; Boei, Jan J. W. A.; Capinha, Liliana; Carta, Giada; Castell, Jose, V; Davoli, Enrico; Drake, Christina; Fisher, Ciaran P.; Heldring, Muriel M.; Islam, Barira; Jennings, Paul; Leist, Marcel; Pellegrino-Coppola, Damiano; Schimming, Johannes P.; Snijders, Kirsten E.; Tolosa, Laia; Water, Bob van de; Vugt-Lussenburg, Barbara M. A. van; Walker, Paul; Wehr, Matthias M.; Wijaya, Lukas S.; Escher, Sylvia E.
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Potential of the zebrafish (Danio rerio) embryo test to discriminate between chemicals of similar molecular structure-a study with valproic acid and 14 of its analogues
errARCHIVES OF TOXICOLOGY
IF6.9
err2022-08-03
err8
errOAAI
errBrotzmann, Katharina; Escher, Sylvia E.; Walker, Paul; Braunbeck, Thomas
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
R
Robert W. Doms
H-index: 111 · Papers: 410
T
Thomas Härtung
H-index: 102 · Papers: 854
M
Matthias Mack
H-index: 101 · Papers: 419
M
Marcel Leist
H-index: 95 · Papers: 459
J
Jan G. Hengstler
H-index: 94 · Papers: 1.1K
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