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Conserved allomorphs of MR1 drive the specificity of MR1-restricted TCRs Cornforth, Terri V.; Moyo, Nathifa; Cole, Suzanne; Lam, Emily P. S.; Lobry, Tatiana; Wolchinsky, Ron; Lloyd, Angharad; Ward, Katarzyna; Denham, Eleanor M.; Masi, Giulia; Qing Yun, Phyllis Tea; Moore, Colin; Dhaouadi, Selsabil; Besra, Gurdyal S.; Veerapen, Natacha; Illing, Patricia T.; Vivian, Julian P.; Raynes, Jeremy M.; Le Nours, Jerome; Purcell, Anthony W.; Kundu, Samit; Silk, Jonathan D.; Williams, Luke; Papa, Sophie; Rossjohn, Jamie; Howie, Duncan; Dukes, Joseph Share Save
Novel hybrids of 1,2,3-triazole-benzoxazole: design, synthesis, and assessment of DprE1 enzyme inhibitors using fluorometric assay and computational analysis Singh, Manisha; Batt, Sarah M.; Canales, Christian S. C.; Pavan, Fernando R.; Kumar, Sethu Arun; Akshatha, Handattu S.; Bhagyalalitha, Meduri; Pujar, Karthik G.; Bidye, Durgesh; Pujar, Gurubasavaraj V.; Besra, Gurdyal S. Share Save
The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth (vol 15, 5740, 2024) Franklin, Aaron; Salgueiro, Vivian C.; Layton, Abigail J.; Sullivan, Rudi; Mize, Todd; Vazquez-Iniesta, Lucia; Benedict, Samuel T.; Gurcha, Sudagar S.; Anso, Itxaso; Besra, Gurdyal S.; Banzhaf, Manuel; Lovering, Andrew L.; Williams, Spencer J.; Guerin, Marcelo E.; Scott, Nichollas E.; Prados-Rosales, Rafael; Lowe, Elisabeth C.; Moynihan, Patrick J. Share Save
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The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth Franklin, Aaron; Salgueiro, Vivian C.; Layton, Abigail J.; Sullivan, Rudi; Mize, Todd; Vazquez-Iniesta, Lucia; Benedict, Samuel T.; Gurcha, Sudagar S.; Anso, Itxaso; Besra, Gurdyal S.; Banzhaf, Manuel; Lovering, Andrew L.; Williams, Spencer J.; Guerin, Marcelo E.; Scott, Nichollas E.; Prados-Rosales, Rafael; Lowe, Elisabeth C.; Moynihan, Patrick J. Share Save
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Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses Chancellor, Andrew; Simmons, Robert Alan; Khanolkar, Rahul C.; Nosi, Vladimir; Beshirova, Aisha; Berloffa, Giuliano; Colombo, Rodrigo; Karuppiah, Vijaykumar; Pentier, Johanne M.; Tubb, Vanessa; Ghadbane, Hemza; Suckling, Richard J.; Page, Keith; Crean, Rory M.; Vacchini, Alessandro; De Gregorio, Corinne; Schaefer, Verena; Constantin, Daniel; Gligoris, Thomas; Lloyd, Angharad; Hock, Miriam; Srikannathasan, Velupillai; Robinson, Ross A.; Besra, Gurdyal S.; Van der Kamp, Marc W.; Mori, Lucia; Calogero, Raffaele; Cole, David K.; De Libero, Gennaro; Lepore, Marco Share Save
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Structure of the priming arabinosyltransferase AftA required for AG biosynthesis of Mycobacterium tuberculosis Gong, Yicheng; Wei, Chuancun; Wang, Jun; Mu, Nengjiang; Lu, Qinhong; Wu, Chengyao; Yan, Ning; Yang, Huifang; Zhao, Yao; Yang, Xiuna; Gurcha, Sudagar S.; Veerapen, Natacha; Batt, Sarah M.; Hao, Zhiqiang; Da, Lintai; Besra, Gurdyal S.; Rao, Zihe; Zhang, Lu Share Save
Lipoproteins act as vehicles for lipid antigen delivery and activation of invariant natural killer T cells Engelen, Suzanne E.; Ververs, Francesca A.; Markovska, Angela; Lagerholm, B. Christoffer; Kraaijenhof, Jordan M.; Yousif, Laura I. E.; Zurke, Yasemin-Xiomara; Gulersonmez, Can M. C.; Kooijman, Sander; Goddard, Michael; van Eijkeren, Robert J.; Jervis, Peter J.; Besra, Gurdyal S.; Haitjema, Saskia; Asselbergs, Folkert W.; Kalkhoven, Eric; Ploegh, Hidde L.; Boes, Marianne; Cerundolo, Vincenzo; Hovingh, G. K.; Salio, Mariolina; Stigter, Edwin C. A.; Rensen, Patrick C. N.; Monaco, Claudia; Schipper, Henk S. Share Save
The proliferation of human mucosal-associated invariant T cells requires a MYC-SLC7A5-glycolysis metabolic axis Kedia-Mehta, Nidhi; Pisarska, Marta M.; Rollings, Christina; O'Neill, Chloe; De Barra, Conor; Foley, Cathriona; Wood, Nicole A. W.; Wrigley-Kelly, Neil; Veerapen, Natacha; Besra, Gurdyal; Bergin, Ronan; Jones, Nicholas; O'Shea, Donal; V. Sinclair, Linda; Hogan, Andrew E. Share Save
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NSC19723, a Thiacetazone-Like Benzaldehyde Thiosemicarbazone Improves the Efficacy of TB Drugs In Vitro and In Vivo Singh, Padam; Rawat, Srishti; Agrahari, Ashish Kumar; Singh, Manisha; Chugh, Saurabh; Gurcha, Sudagar; Singh, Albel; Abrahams, Katherine; Besra, Gurdyal S.; Asthana, Shailendra; Rawat, Diwan S.; Singh, Ramandeep Share Save
Quantitative affinity measurement of small molecule ligand binding to major histocompatibility complex class-I-related protein 1 MR1 Wang, Carl J. H.; Awad, Wael; Liu, Ligong; Mak, Jeffrey Y. W.; Veerapen, Natacha; Illing, Patricia T.; Purcell, Anthony W.; Eckle, Sidonia B. G.; McCluskey, James; Besra, Gurdyal S.; Fairlie, David P.; Rossjohn, Jamie; Le Nours, Jerome Share Save
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Sortase A-Cleavable CD1d Identifies Sphingomyelins as Major Class of CD1d-Associated Lipids Rudolph, Maren; Wang, Yuting; Simolka, Theresa; Huc-Claustre, Emilie; Dai, Lingyun; Grotenbreg, Gijsbert; Besra, Gurdyal Singh; Shevchenko, Anna; Shevchenko, Andrej; Zeissig, Sebastian Share Save
GSK2556286 Is a Novel Antitubercular Drug Candidate Effective In Vivo with the Potential To Shorten Tuberculosis Treatment Nuermberger, Eric L.; Martinez-Martinez, Maria Santos; Sanz, Olalla; Urones, Beatriz; Esquivias, Jorge; Soni, Heena; Tasneen, Rokeya; Tyagi, Sandeep; Li, Si-Yang; Converse, Paul J.; Boshoff, Helena I.; Robertson, Gregory T.; Besra, Gurdyal S.; Abrahams, Katherine A.; Upton, Anna M.; Mdluli, Khisimuzi; Boyle, Gary W.; Turner, Sam; Fotouhi, Nader; Cammack, Nicholas C.; Siles, Juan Miguel; Alonso, Marta; Escribano, Jaime; Lelievre, Joel; Rullas-Trincado, Joaquin; Perez-Herran, Esther; Bates, Robert H.; Maher-Edwards, Gareth; Barros, David; Ballell, Lluis; Jimenez, Elena Share Save
Identification of thiophene-benzenesulfonamide derivatives for the treatment of multidrug-resistant tuberculosis Qin, Rongfei; Wang, Pengxu; Wang, Bin; Fu, Lei; Batt, Sarah M.; Besra, Gurdyal S.; Wu, Chengwei; Wang, Yanan; Huang, Haihong; Lu, Yu; Li, Gang Share Save
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