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C

Christian Haass

german center for neurodegenerative diseases

135H-index
665Paper Count
7.5WCitation Count
Published Papers 300
Publication Date
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A reproducible three-dimensional model of human brain tissue to investigate physiological and disease-associated microglia phenotypes
errNature Neuroscience
IF20
err2026-08-04
err0
errOAAI
errJulien Klimmt; Carolina Cardoso Gonçalves; Jessica Valentina Montgomery; Stephan A. Müller; Merle Bublitz; Severin Filser; Lars Paeger; Brigitte Nuscher; Angelika Dannert; Sigrun Roeber; Veronica Pravata; Martina Schifferer; Joshua J. Shrouder; Nathalie Schulz; Judit González-Gallego; Silvia Cappello; Thomas Misgeld; Nikolaus Plesnila; Eduardo Beltrán; Jochen Herms; Elena De Domenico; Marc D. Beyer; Joachim L. Schultze; Christian Haass; Stefan F. Lichtenthaler; Caterina Carraro; Dominik Paquet
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Attitudes of specialist memory-clinic patients with early symptomatic Alzheimer’s disease towards lecanemab: results from a multicenter survey in Europe
errScientific Reports
IF3.9
err2026-07-09
err0
errOAAI
errJonathan Vöglein; Johannes Levin; Elisabeth Stögmann; Christian Haass; Günter U. Höglinger; Lutz Frölich; Frank Jessen
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errSave
Microglial TDP-43 mediates myelin refinement and represses Tyrobp cryptic exon inclusion in mice
errNature Neuroscience
IF20
err2026-07-08
err0
errOAAI
errAnne-Claire Compagnion; Andranik Ivanov; Anil Rana; Felipe Espinoza; Thomas Sandmann; Fanny S. Martineau; Katia Monsorno; Roberta Facchinetti; Alessandro Matera; Lionel Rougé; Fernando González Ibáñez; Clarissa Catale; Matteo Bizzotto; Sonia Garel; Michela Matteoli; Yutaro Kashiwagi; Ryuta Koyama; Christian Haass; Marie-Eve Tremblay; Dieter Beule; Ileana Jelescu; Valerio Zerbi; Gilbert Di Paolo; Rosa C. Paolicelli
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errSave
TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism
errNature Communications
IF15.7
err2026-01-24
err0
errOAAI
errAstrid F. Feiten; Kilian Dahm; Kai Schlepckow; Bettina van Lengerich; Jung H. Suh; Anika Reifschneider; Benedikt Wefers; Laura M. Bartos; Karin Wind-Mark; Lis de Weerd; Thomas Ulas; Elena De-Domenico; Pia Grundschöttel; Stefan Paulusch; Benjamin Tast; Tamisa Honda; Stephan A. Müller; Matthias Becker; Igor Khalin; Alessio Ricci; Arthur Liesz; Bettina Brunner; Claudia Krenner; Katrin Buschmann; Brigitte Nuscher; Lena Spieth; Niklas Junker; Stefan A. Berghoff; Sonnet S. Davis; Jonas J. Neher; Wolfgang Wurst; Nikolaus Plesnila; Joseph W. Lewcock; Mikael Simons; Stefan F. Lichtenthaler; Gilbert Di Paolo; Matthias Brendel; Anja Capell; Kathryn M. Monroe; Joachim L. Schultze; Christian Haass
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Blood-Brain Barrier Penetrating Copper-64 TREM2 Antibody Enables Targeted PET Imaging of Tumor-Associated Immune Cells in Glioblastoma Mouse Models
errNuclear Medicine and Biology
IF3
err2025-11-10
err0
PREAI
errMarlies Haertel; Rebecca Schaefer; Lea H. Kunze; Ha Eun Park; Leonie Hoermann; Kai Schlepckow; Franz Josef Gildehaus; Christian Haass; Joseph W. Lewcock; Kathryn M. Monroe; Nathalie L. Albert; Louisa von Baumgarten; Sibylle Ziegler; Simon Lindner; Matthias Brendel; Laura M. Bartos
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“The DESCRIBE-ALS-FTD study: a prospective multicenter observational study of the ALS-FTD spectrum”
errAmyotrophic Lateral Sclerosis and Frontotemporal Degeneration
IF2.8
err2025-06-09
err0
errOAAI
errAndreas Hermann; Johannes Prudlo; Elisabeth Kasper; Matthis Synofzik; Oliver Peters; Josef Priller; Elisabeth Dinter; Jens Wiltfang; Inga Zerr; Agnes Flöel; Katharina Bürger; Günter U. Höglinger; Johannes Levin; Emrah Düzel; Stefan Teipel; Lukas Beichert; Frederic Brosseron; Michael Wagner; Ingo Frommann; Alfredo Ramirez; Renat Yakupov; Matthias Schmid; Paul Lingor; Christian Haass; Annika Spottke; René Günther; Patrick Weydt; Manuela Neumann; Anja Schneider
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The late-onset Alzheimer's disease risk factor RHBDF2 is a modifier of microglial TREM2 proteolysis
errLIFE SCIENCE ALLIANCE
IF2.9
err2025-03-13
err0
errOAAI
errJocher, Georg; Ozcelik, Gozde; Mueller, Stephan A.; Hsia, Hung-En; Lastra Osua, Miranda; Hofmann, Laura, I; Assfalg, Marlene; Dinkel, Lina; Feng, Xiao; Schlepckow, Kai; Willem, Michael; Haass, Christian; Tahirovic, Sabina; Blobel, Carl P.; Lichtenthaler, Stefan F.
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Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology
errIMMUNITY
IF26.3
err2024-11-01
err2
errOAAI
errKaji, Seiji; Berghoff, Stefan A.; Spieth, Lena; Schlaphoff, Lennart; Sasmita, Andrew O.; Vitale, Simona; Bueschgens, Luca; Kedia, Shreeya; Zirngibl, Martin; Nazarenko, Taisiia; Damkou, Alkmini; Hosang, Leon; Depp, Constanze; Kamp, Frits; Scholz, Patricia; Ewers, David; Giera, Martin; Ischebeck, Till; Wurst, Wolfgang; Wefers, Benedikt; Schifferer, Martina; Willem, Michael; Nave, Klaus-Armin; Haass, Christian; Arzberger, Thomas; Jaekel, Sarah; Wirths, Oliver; Saher, Gesine; Simons, Mikael
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errSave
Divisions over the regulation of lecanemab
errLANCET
IF88.5
err2024-11-01
err0
PREAI
errDe Strooper, Bart; Haass, Christian; Hardy, John; Zetterberg, Henrik
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errSave
Correction to: Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins
errACTA NEUROPATHOLOGICA
IF9.3
err2024-10-05
err0
PREAI
errMori, Kohji; Arzberger, Thomas; Graesser, Friedrich A.; Gijselinck, Ilse; May, Stephanie; Rentzsch, Kristin; Weng, Shih-Ming; Schludi, Martin H.; van der Zee, Julie; Cruts, Marc; Van Broeckhoven, Christine; Kremmer, Elisabeth; Kretzschmar, Hans A.; Haass, Christian; Edbauer, Dieter
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errSave
Regional desynchronization of microglial activity is associated with cognitive decline in Alzheimer's disease
errMOLECULAR NEURODEGENERATION
IF17.5
err2024-09-05
err0
errOAAI
errZatcepin, Artem; Gnoerich, Johannes; Rauchmann, Boris-Stephan; Bartos, Laura M.; Wagner, Stephan; Franzmeier, Nicolai; Malpetti, Maura; Xiang, Xianyuan; Shi, Yuan; Parhizkar, Samira; Grosch, Maximilian; Wind-Mark, Karin; Kunte, Sebastian T.; Beyer, Leonie; Meyer, Carolin; Broesamle, Desiree; Wendeln, Ann-Christin; Osei-Sarpong, Collins; Heindl, Steffanie; Liesz, Arthur; Stoecklein, Sophia; Biechele, Gloria; Finze, Anika; Eckenweber, Florian; Lindner, Simon; Rominger, Axel; Bartenstein, Peter; Willem, Michael; Tahirovic, Sabina; Herms, Jochen; Buerger, Katharina; Simons, Mikael; Haass, Christian; Rupprecht, Rainer; Riemenschneider, Markus J.; Albert, Nathalie L.; Beyer, Marc; Neher, Jonas J.; Paeger, Lars; Levin, Johannes; Hoeglinger, Guenter U.; Perneczky, Robert; Ziegler, Sibylle I.; Brendel, Matthias
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Physiological roles of α-synuclein serine-129 phosphorylation - not an oxymoron
errTRENDS IN NEUROSCIENCES
IF15.1
err2024-07-01
err3
PREAI
errRamalingam, Nagendran; Haass, Christian; Dettmer, Ulf
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Mis-localization of endogenous TDP-43 leads to ALS-like early-stage metabolic dysfunction and progressive motor deficits
errMOLECULAR NEURODEGENERATION
IF17.5
err2024-06-20
err1
errOAAI
errHu, Yiying; Hruscha, Alexander; Pan, Chenchen; Schifferer, Martina; Schmidt, Michael K.; Nuscher, Brigitte; Giera, Martin; Kostidis, Sarantos; Burhan, Ozge; van Bebber, Frauke; Edbauer, Dieter; Arzberger, Thomas; Haass, Christian; Schmid, Bettina
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Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons (vol 23, e53890, 2022)
errEMBO REPORTS
IF6.2
err2024-06-07
err0
errOAAI
errRiemenschneider, Henrick; Guo, Qiang; Bader, Jakob; Frottin, Frederic; Farny, Daniel; Kleinberger, Gernot; Haass, Christian; Mann, Matthias; Hartl, F. Ulrich; Baumeister, Wolfgang; Hipp, Mark S.; Meissner, Felix; Fernandez-Busnadiego, Ruben; Edbauer, Dieter
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Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2024-06-05
err0
PREAI
errReich, Marvin; Simon, Matthew J.; Polke, Beate; Paris, Inaki; Werner, Georg; Schrader, Christian; Spieth, Lena; Davis, Sonnet S.; Robinson, Sophie; de Melo, Gabrielly Lunkes; Schlaphoff, Lennart; Buschmann, Katrin; Berghoff, Stefan; Logan, Todd; Nuscher, Brigitte; de Weerd, Lis; Edbauer, Dieter; Simons, Mikael; Suh, Jung H.; Sandmann, Thomas; Kariolis, Mihalis S.; Devos, Sarah L.; Lewcock, Joseph W.; Paquet, Dominik; Capell, Anja; Di Paolo, Gilbert; Haass, Christian
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Proteomics of mouse brain endothelium uncovers dysregulation of vesicular transport pathways during aging
errNATURE AGING
IF19.4
err2024-03-22
err3
errOAAI
errTodorov-Voelgyi, Katalin; Gonzalez-Gallego, Judit; Mueller, Stephan A.; Beaufort, Nathalie; Malik, Rainer; Schifferer, Martina; Todorov, Mihail Ivilinov; Crusius, Dennis; Robinson, Sophie; Schmidt, Andree; Koerbelin, Jakob; Bareyre, Florence; Ertuerk, Ali; Haass, Christian; Simons, Mikael; Paquet, Dominik; Lichtenthaler, Stefan F.; Dichgans, Martin
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TREM2 protects from atherosclerosis by limiting necrotic core formation
errcardiovascular research
IF10.8
err2024-03-12
err6
errOAAI
errPiollet, Marie; Porsch, Florentina; Rizzo, Giuseppe; Kapser, Frederieke; Schulz, Dirk J. J.; Kiss, Mate G.; Schlepckow, Kai; Morenas-Rodriguez, Estrella; Sen, Mustafa Orkun; Gropper, Julius; Bandi, Sourish Reddy; Schaefer, Sarah; Krammer, Tobias; Leipold, Alexander M.; Hoke, Matthias; Ozsvar-Kozma, Maria; Benes, Hannah; Schillinger, Martin; Minar, Erich; Roesch, Melanie; Goederle, Laura; Hladik, Anastasiya; Knapp, Sylvia; Colonna, Marco; Martini, Rudolf; Saliba, Antoine-Emmanuel; Haass, Christian; Zernecke, Alma; Binder, Christoph J.; Cochain, Clement
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Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2
errJOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
err2024-01-30
err9
errOAAI
errYu, Chen; Lad, Eleonora M.; Mathew, Rose; Shiraki, Nobuhiko; Littleton, Sejiro; Chen, Yun; Hou, Jinchao; Schlepckow, Kai; Degan, Simone; Chew, Lindsey; Amason, Joshua; Kalnitsky, Joan; Bowes Rickman, Catherine; Proia, Alan D.; Colonna, Marco; Haass, Christian; Saban, Daniel R.
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Association of Neurofilament Light Chain, [18F]PI-2620 Tau-PET, TSPO-PET, and Clinical Progression in Patients With β-Amyloid-Negative CBS
errNEUROLOGY
IF8.5
err2024-01-09
err2
PREAI
errPalleis, Carla; Franzmeier, Nicolai; Weidinger, Endy; Bernhardt, Alexander M.; Katzdobler, Sabrina; Wall, Stephan; Ferschmann, Christian; Harris, Stefanie; Schmitt, Julia; Schuster, Sebastian; Gnoerich, Johannes; Finze, Anika; Biechele, Gloria; Lindner, Simon; Albert, Nathalie L.; Bartenstein, Peter; Sabri, Osama; Barthel, Henryk; Rupprecht, Rainer; Nuscher, Brigitte; Stephens, Andrew W.; Rauchmann, Boris-Stephan; Perneczky, Robert; Haass, Christian; Brendel, Matthias; Levin, Johannes; Hoeglinger, Guenter U.
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PET imaging of microglia in Alzheimer's disease using-64 labeled TREM2 antibodies
errTHERANOSTICS
IF13.3
err2024-01-01
err0
errOAAI
errShojaei, Monireh; Schaefer, Rebecca; Schlepckow, Kai; Kunze, Lea H.; Struebing, Felix L.; Brunner, Bettina; Willem, Michael; Bartos, Laura M.; Feiten, Astrid; Palumbo, Giovanna; Arzberger, Thomas; Bartenstein, Peter; Parico, Gian Carlo; Xia, Dan; Monroe, Kathryn M.; Haass, Christian; Brendel, Matthias; Lindner, Simon
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Research Directions

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Co-authors
Cooperation Journals
M
Matthias Mann
H-index: 250 · Papers: 1.4K
K
Kaj Blennow
H-index: 214 · Papers: 3.6K
J
John C. Morris
H-index: 212 · Papers: 2.4K
J
John Hardy
H-index: 207 · Papers: 1.9K
D
David M. Holtzman
H-index: 204 · Papers: 1.0K
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