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SaveComparison of the immunogenicity of mRNA-encoded and protein HIV-1 Env-ferritin nanoparticle designs
Mu, Zekun; Whitley, Jill; Martik, Diana; Sutherland, Laura; Newman, Amanda; Barr, Maggie; Parks, Robert; Wiehe, Kevin; Cain, Derek W.; Hodges, Katrina Z.; Venkatayogi, Sravani; Lee, Esther M.; Smith, Lena; Mansouri, Katayoun; Edwards, Robert J.; Wang, Yunfei; Rountree, Wes; Alameh, Mohamad-Gabriel; Tam, Ying; Barbosa, Christopher; Tomai, Mark; Lewis, Mark G.; Santrai, Sampa; Maughan, Maureen; Tian, Ming; Alt, Frederick W.; Weissman, Drew; Saunders, Kevin O.; Haynes, Barton F. Share Save Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding siteCaniels, Tom G.; Medina-Ramirez, Max; Zhang, Shiyu; Kratochvil, Sven; Xian, Yuejiao; Koo, Ja-Hyun; Derking, Ronald; Samsel, Jakob; van Schooten, Jelle; Pecetta, Simone; Lamperti, Edward; Yuan, Meng; Carrasco, Maria Rios; del Moral Sanchez, Ivan; Allen, Joel D.; Bouhuijs, Joey H.; Yasmeen, Anila; Ketas, Thomas J.; Snitselaar, Jonne L.; Bijl, Tom P. L.; Martin, Isabel Cuella; Torres, Jonathan L.; Cupo, Albert; Shirreff, Lisa; Rogers, Kenneth; Mason, Rosemarie D.; Roederer, Mario; Greene, Kelli M.; Gao, Hongmei; Silva, Catarina Mendes; Baken, Isabel J. L.; Tian, Ming; Alt, Frederick W.; Pulendran, Bali; Seaman, Michael S.; Crispin, Max; van Gils, Marit J.; Montefiori, David C.; McDermott, Adrian B.; Villinger, Francois J.; Koup, Richard A.; Moore, John P.; Klasse, Per Johan; Ozorowski, Gabriel; Batista, Facundo D.; Wilson, Ian A.; Ward, Andrew B.; Sanders, Rogier W. Share Save Vaccination induces broadly neutralizing antibody precursors to HIV gp41 (vol 25, pg 1073, 2024)Schiffner, Torben; Phung, Ivy; Ray, Rashmi; Irimia, Adriana; Tian, Ming; Swanson, Olivia; Lee, Jeong Hyun; Lee, Chang-Chun D.; Marina-Zarate, Ester; Cho, So Yeon; Huang, Jiachen; Ozorowski, Gabriel; Skog, Patrick D.; Serra, Andreia M.; Rantalainen, Kimmo; Allen, Joel D.; Baboo, Sabyasachi; Rodriguez, Oscar L.; Himansu, Sunny; Zhou, Jianfu; Hurtado, Jonathan; Flynn, Claudia T.; McKenney, Katherine; Havenar-Daughton, Colin; Saha, Swati; Shields, Kaitlyn; Schultze, Steven; Smith, Melissa L.; Liang, Chi-Hui; Toy, Laura; Pecetta, Simone; Lin, Ying-Cing; Willis, Jordan R.; Sesterhenn, Fabian; Kulp, Daniel W.; Hu, Xiaozhen; Cottrell, Christopher A.; Zhou, Xiaoya; Ruiz, Jennifer; Wang, Xuesong; Nair, Usha; Kirsch, Kathrin H.; Cheng, Hwei-Ling; Davis, Jillian; Kalyuzhniy, Oleksandr; Liguori, Alessia; Diedrich, Jolene K.; Ngo, Julia T.; Lewis, Vanessa; Phelps, Nicole; Tingle, Ryan D.; Spencer, Skye; Georgeson, Erik; Adachi, Yumiko; Kubitz, Michael; Eskandarzadeh, Saman; Elsliger, Marc A.; Amara, Rama R.; Landais, Elise; Briney, Bryan; Burton, Dennis R.; Carnathan, Diane G.; Silvestri, Guido; Watson, Corey T.; Yates, John R.; Paulson, James C.; Crispin, Max; Grigoryan, Gevorg; Ward, Andrew B.; Sok, Devin; Alt, Frederick W.; Wilson, Ian A.; Batista, Facundo D.; Crotty, Shane; Schief, William R. Share Save Vaccination induces broadly neutralizing antibody precursors to HIV gp41Schiffner, Torben; Phung, Ivy; Ray, Rashmi; Irimia, Adriana; Tian, Ming; Swanson, Olivia; Lee, Jeong Hyun; Lee, Chang-Chun D.; Marina-Zarate, Ester; Cho, So Yeon; Huang, Jiachen; Ozorowski, Gabriel; Skog, Patrick D.; Serra, Andreia M.; Rantalainen, Kimmo; Allen, Joel D.; Baboo, Sabyasachi; Rodriguez, Oscar L.; Himansu, Sunny; Zhou, Jianfu; Hurtado, Jonathan; Flynn, Claudia T.; Mckenney, Katherine; Havenar-Daughton, Colin; Saha, Swati; Shields, Kaitlyn; Schulze, Steven; Smith, Melissa L.; Liang, Chi-Hui; Toy, Laura; Pecetta, Simone; Lin, Ying-Cing; Willis, Jordan R.; Sesterhenn, Fabian; Kulp, Daniel W.; Hu, Xiaozhen; Cottrell, Christopher A.; Zhou, Xiaoya; Ruiz, Jennifer; Wang, Xuesong; Nair, Usha; Kirsch, Kathrin H.; Cheng, Hwei-Ling; Davis, Jillian; Kalyuzhniy, Oleksandr; Liguori, Alessia; Diedrich, Jolene K.; Ngo, Julia T.; Lewis, Vanessa; Phelps, Nicole; Tingle, Ryan D.; Spencer, Skye; Georgeson, Erik; Adachi, Yumiko; Kubitz, Michael; Eskandarzadeh, Saman; Elsliger, Marc A.; Amara, Rama R.; Landais, Elise; Briney, Bryan; Burton, Dennis R.; Carnathan, Diane G.; Silvestri, Guido; Watson, Corey T.; Yates III, John R.; Paulson, James C.; Crispin, Max; Grigoryan, Gevorg; Ward, Andrew B.; Sok, Devin; Alt, Frederick W.; Wilson, Ian A.; Batista, Facundo D.; Crotty, Shane; Schief, William R. Share Save Share Save Share Save Humanized V(D)J-rearranging and TdT-expressing mouse vaccine models with physiological HIV-1 broadly neutralizing antibody precursorsLuo, Sai; Jing, Changbin; Ye, Adam Yongxin; Kratochvil, Sven; Cottrell, Christopher A.; Koo, Ja-Hyun; Williams, Aimee Chapdelaine; Francisco, Lucas Vieira; Batra, Himanshu; Lamperti, Edward; Kalyuzhniy, Oleksandr; Zhang, Yuxiang; Barbieri, Alessandro; Manis, John P.; Haynes, Barton F.; Schief, William R.; Batista, Facundo D.; Tian, Ming; Alt, Frederick W. Share Save An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusionLuo, Sai; Zhang, Jun; Kreutzberger, Alex J. B.; Eaton, Amanda; Edwards, Robert J.; Jing, Changbin; Dai, Hai-Qiang; Sempowski, Gregory D.; Cronin, Kenneth; Parks, Robert; Ye, Adam Yongxin; Mansouri, Katayoun; Barr, Maggie; Pishesha, Novalia; Williams, Aimee Chapdelaine; Francisco, Lucas Vieira; Saminathan, Anand; Peng, Hanqin; Batra, Himanshu; Bellusci, Lorenza; Khurana, Surender; Alam, S. Munir; Montefiori, David C.; Saunders, Kevin O.; Tian, Ming; Ploegh, Hidde; Kirchhausen, Tom; Chen, Bing; Haynes, Barton F.; Alt, Frederick W. Share Save mRNA-encoded HIV-1 Env trimer ferritin nanoparticles induce monoclonal antibodies that neutralize heterologous HIV-1 isolates in miceMu, Zekun; Wiehe, Kevin; Saunders, Kevin O.; Henderson, Rory; Cain, Derek W.; Parks, Robert; Martik, Diana; Mansouri, Katayoun; Edwards, Robert J.; Newman, Amanda; Lu, Xiaozhi; Shi-Mao Xia; Eaton, Amanda; Bonsignori, Mattia; Montefiori, David; Han, Qifeng; Venkatayogi, Sravani; Evangelous, Tyler; Wang, Yunfei; Rountree, Wes; Korber, Bette; Wagh, Kshitij; Tam, Ying; Barbosa, Christopher; Alam, S. Munir; Williams, Wilton B.; Tian, Ming; Alt, Frederick W.; Pardi, Norbert; Weissman, Drew; Haynes, Barton F. Share Save Share Save An in vivo method for diversifying the functions of therapeutic antibodiesTian, Ming; Cheng, Hwei-Ling; Kimble, Michael T.; McGovern, Kelly; Waddicor, Peyton; Chen, Yiwei; Cantor, Elizabeth; Qiu, Mengting; Tuchel, Marie-Elen; Dao, Mai; Alt, Frederick W. Share Save Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadthChen, Xuejun; Zhou, Tongqing; Schmidt, Stephen D.; Duan, Hongying; Cheng, Cheng; Chuang, Gwo-Yu; Gu, Ying; Louder, Mark K.; Lin, Bob C.; Shen, Chen-Hsiang; Sheng, Zizhang; Zheng, Michelle X.; Doria-Rose, Nicole A.; Joyce, M. Gordon; Shapiro, Lawrence; Tian, Ming; Alt, Frederick W.; Kwong, Peter D.; Mascola, John R. Share Save Share Save Conditional antibody expression to avoid central B cell deletion in humanized HIV-1 vaccine mouse modelsTian, Ming; McGovern, Kelly; Cheng, Hwei-Ling; Waddicor, Peyton; Rieble, Lisa; Dao, Mai; Chen, Yiwei; Kimble, Michael T.; Cantor, Elizabeth; Manfredonia, Nicole; Judson, Rachael; Chapdelaine-Williams, Aimee; Cain, Derek W.; Haynes, Barton F.; Alt, Frederick W. Share Save Immune checkpoint modulation enhances HIV-1 antibody inductionBradley, Todd; Kuraoka, Masayuki; Yeh, Chen-Hao; Tian, Ming; Chen, Huan; Cain, Derek W.; Chen, Xuejun; Cheng, Cheng; Ellebedy, Ali H.; Parks, Robert; Barr, Maggie; Sutherland, Laura L.; Scearce, Richard M.; Bowman, Cindy M.; Bouton-Verville, Hilary; Santra, Sampa; Wiehe, Kevin; Lewis, Mark G.; Ogbe, Ane; Borrow, Persephone; Montefiori, David; Bonsignori, Mattia; Moody, M. Anthony; Verkoczy, Laurent; Saunders, Kevin O.; Ahmed, Rafi; Mascola, John R.; Kelsoe, Garnett; Alt, Frederick W.; Haynes, Barton F. Share Save Targeting peptide-enhanced antibody and CD11c+ dendritic cells to inclusion bodies expressing protective antigen against ETEC in miceJiang, Xinpeng; Xia, Shuang; He, Xinmiao; Ma, Hong; Feng, Yanzhong; Liu, Ziguang; Wang, Wentao; Tian, Ming; Chen, Heshu; Peng, Fugang; Wang, Liang; Zhao, Peng; Ge, Junwei; Liu, Di Share Save Share Save Glycan Masking Focuses Immune Responses to the HIV-1 CD4-Binding Site and Enhances Elicitation of VRC01-Class Precursor AntibodiesDuan, Hongying; Chen, Xuejun; Boyington, Jeffrey C.; Cheng, Cheng; Zhang, Yi; Jafari, Alexander J.; Stephens, Tyler; Tsybovsky, Yaroslav; Kalyuzhniy, Oleksandr; Zhao, Peng; Menis, Sergey; Nason, Martha C.; Normandin, Erica; Mukhamedova, Maryam; DeKosky, Brandon J.; Wells, Lance; Schief, William R.; Tian, Ming; Alt, Frederick W.; Kwong, Peter D.; Mascola, John R. Share Save Share Save 
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