Not logged in Optimization of VE607 to generate analogs with improved neutralization activities against SARS-CoV-2 variants Ding, Shilei; Yang, Derek; Ullah, Irfan; Niu, Ling; Unger, Matthew; Diaz-Salinas, Marco A.; Chandravanshi, Monika; Zhou, Fei; Beaudoin-Bussieres, Guillaume; Benlarbi, Mehdi; Tolbert, William D.; Yoon, Keon-Woong; Xu, Ruixue; Laroche, Genevieve; Gaudette, Fleur; Morton, Abraham J.; Lang, Zabrina C.; Son, Anna; Abrams, Cameron; Cote, Marceline; Smith III, Amos B.; Huang, Rick K.; Matthies, Doreen; Munro, James B.; Pazgier, Marzena; Uchil, Pradeep D.; Finzi, Andres Share Save
Fostemsavir Decreases the Levels of Anti-gp120 CD4-Induced Antibodies in Heavily Treatment-Experienced People With HIV Benlarbi, Mehdi; Richard, Jonathan; Clemente, Tommaso; Bourassa, Catherine; Tolbert, William D.; Prakash, Manyu; Chandravanshi, Monika; Clark, Andrew; Pazgier, Marzena; Durand, Madeleine; Castagna, Antonella; Finzi, Andres Share Save
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A gp41 HR2 residue modulates the susceptibility of HIV-1 envelope glycoproteins to small molecule inhibitors targeting gp120 Chatterjee, Debashree; Niu, Ling; Medjahed, Halima; Ding, Shilei; Benlarbi, Mehdi; Belanger, Etienne; Prevost, Jeremie; Chen, Hung-Ching; Tolbert, William D.; Smith III, Amos B.; Pazgier, Marzena; Finzi, Andres Share Save
Optimization of a Piperidine CD4-Mimetic Scaffold Sensitizing HIV-1 Infected Cells to Antibody-Dependent Cellular Cytotoxicity Lee, Daniel; Niu, Ling; Ding, Shilei; Zhu, Huile; Tolbert, William D.; Medjahed, Halima; Beaudoin-Bussieres, Guillaume; Abrams, Cameron; Finzi, Andres; Pazgier, Marzena; Smith III, Amos B. Share Save
The combination of three CD4-induced antibodies targeting highly conserved Env regions with a small CD4-mimetic achieves potent ADCC activity Marchitto, Lorie; Richard, Jonathan; Prevost, Jeremie; Tauzin, Alexandra; Yang, Derek; Chiu, Ta-Jung; Chen, Hung-Ching; Diaz-Salinas, Marco A.; Nayrac, Manon; Benlarbi, Mehdi; Beaudoin-Bussieres, Guillaume; Anand, Sai Priya; Dionne, Katrina; Belanger, Etienne; Chatterjee, Debashree; Medjahed, Halima; Bourassa, Catherine; Tolbert, William D.; Hahn, Beatrice H.; Munro, James B.; Pazgier, Marzena; Smith III, Amos B.; Finzi, Andres Share Save
Three families of CD4-induced antibodies are associated with the capacity of plasma from people living with HIV to mediate ADCC in the presence of CD4-mimetics Tauzin, Alexandra; Marchitto, Lorie; Belanger, Etienne; Benlarbi, Mehdi; Beaudoin-Bussieres, Guillaume; Prevost, Jeremie; Yang, Derek; Chiu, Ta-Jung; Chen, Hung-Ching; Bourassa, Catherine; Medjahed, Halima; Korzeniowski, Marek K.; Gottumukkala, Suneetha; Tolbert, William D.; Richard, Jonathan; Smith III, Amos B.; Pazgier, Marzena; Finzi, Andres Share Save
Immune response profiles from humans experimentally exposed to Phlebotomus duboscqi bites de Araujo, Fernanda Fortes; Abdeladhim, Maha; Teixeira, Clarissa; Hummer, Kelly; Wilkerson, Matthew D.; Ressner, Roseanne; Lakhal-Naouar, Ines; Ellis, Michael W.; Meneses, Claudio; Nurmukhambetova, Saule; Gomes, Regis; Tolbert, W. David; Turiansky, George W.; Pazgier, Marzena; Oliveira, Fabiano; Valenzuela, Jesus G.; Kamhawi, Shaden; Aronson, Naomi Share Save
Defining genetic diversity of rhesus macaque Fcγ receptors with long-read RNA sequencing Conley, Haleigh E.; He, Max M.; Easterhoff, David; Kirshner, Helene Fradin; Cocklin, Sarah L.; Meyer, Jacob; Hoxie, Taylor; Berry, Madison; Bradley, Todd; Tolbert, William D.; Pazgier, Marzena; Tomaras, Georgia D.; Schmitz, Joern E.; Moody, Michael Anthony; Wiehe, Kevin; Pollara, Justin Share Save
Plasma Human Immunodeficiency Virus 1 Soluble Glycoprotein 120 Association With Correlates of Immune Dysfunction and Inflammation in Antiretroviral Therapy-Treated Individuals With Undetectable Viremia Benlarbi, Mehdi; Richard, Jonathan; Bourassa, Catherine; Tolbert, William D.; Chartrand-Lefebvre, Carl; Gendron-Lepage, Gabrielle; Sylla, Mohamed; El-Far, Mohamed; Messier-Peet, Marc; Guertin, Camille; Turcotte, Isabelle; Fromentin, Remi; Verly, Myriam Maude; Prevost, Jeremie; Clark, Andrew; Mothes, Walther; Kaufmann, Daniel E.; Maldarelli, Frank; Chomont, Nicolas; Begin, Philippe; Tremblay, Cecile; Baril, Jean-Guy; Trottier, Benoit; Trottier, Sylvie; Duerr, Ralf; Pazgier, Marzena; Durand, Madeleine; Finzi, Andres Share Save
Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir Prevost, Jeremie; Chen, Yaozong; Zhou, Fei; Tolbert, William D.; Gasser, Romain; Medjahed, Halima; Nayrac, Manon; Nguyen, Dung N.; Gottumukkala, Suneetha; Hessell, Ann J.; Rao, Venigalla B.; Pozharski, Edwin; Huang, Rick K.; Matthies, Doreen; Finzi, Andres; Pazgier, Marzena Share Save
The molecular basis of the neutralization breadth of the RBD-specific antibody CoV11 Tolbert, William D.; Chen, Yaozong; Sun, Lulu; Benlarbi, Mehdi; Ding, Shilei; Manickam, Rohini; Pangaro, Emily; Nguyen, Dung N.; Gottumukkala, Suneetha; Cote, Marceline; Gonzalez, Frank J.; Finzi, Andres; Tehrani, Zahra R.; Sajadi, Mohammad M.; Pazgier, Marzena Share Save
Piperidine CD4-Mimetic Compounds Expose Vulnerable Env Epitopes Sensitizing HIV-1-Infected Cells to ADCC Ding, Shilei; Tolbert, William D.; Zhu, Huile; Lee, Daniel; Marchitto, Lorie; Higgins, Tyler; Zhao, Xuchen; Nguyen, Dung; Sherburn, Rebekah; Richard, Jonathan; Gendron-Lepage, Gabrielle; Medjahed, Halima; Mohammadi, Mohammadjavad; Abrams, Cameron; Pazgier, Marzena; Smith, Amos B., III; Finzi, Andres Share Save
Temsavir blocks the immunomodulatory activities of HIV-1 soluble gp120 Richard, Jonathan; Prevost, Jeremie; Bourassa, Catherine; Brassard, Nathalie; Boutin, Marianne; Benlarbi, Mehdi; Goyette, Guillaume; Medjahed, Halima; Gendron-Lepage, Gabrielle; Gaudette, Fleur; Chen, Hung-Ching; Tolbert, William D.; Smith, Amos B., III; Pazgier, Marzena; Dube, Mathieu; Clark, Andrew; Mothes, Walther; Kaufmann, Daniel E.; Finzi, Andres Share Save
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Characterization of a Novel CD4 Mimetic Compound YIR-821 against HIV-1 Clinical Isolates Matsumoto, Kaho; Kuwata, Takeo; Tolbert, William D.; Richard, Jonathan; Ding, Shilei; Prevost, Jeremie; Takahama, Shokichi; Judicate, George P.; Ueno, Takamasa; Nakata, Hirotomo; Kobayakawa, Takuya; Tsuji, Kohei; Tamamura, Hirokazu; Smith, Amos B., III; Pazgier, Marzena; Finzi, Andres; Matsushita, Shuzo Share Save
Decoding human-macaque interspecies differences in Fc-effector functions: The structural basis for CD16-dependent effector function in Rhesus macaques Tolbert, William D. D.; Gohain, Neelakshi; Kremer, Paul G. G.; Hederman, Andrew P. P.; Nguyen, Dung N. N.; Van, Verna; Sherburn, Rebekah; Lewis, George K. K.; Finzi, Andres; Pollara, Justin; Ackerman, Margaret E. E.; Barb, Adam W. W.; Pazgier, Marzena Share Save
Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities Chen, Yaozong; Sun, Lulu; Ullah, Irfan; Beaudoin-Bussieres, Guillaume; Anand, Sai Priya; Hederman, Andrew P.; Tolbert, William D.; Sherburn, Rebekah; Nguyen, Dung N.; Marchitto, Lorie; Ding, Shilei; Wu, Di; Luo, Yuhong; Gottumukkala, Suneetha; Moran, Sean; Kumar, Priti; Piszczek, Grzegorz; Mothes, Walther; Ackerman, Margaret E.; Finzi, Andres; Uchil, Pradeep D.; Gonzalez, Frank J.; Pazgier, Marzena Share Save
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