Yi Zhu - Publications, H-index & Citations

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朱

朱益 (Yi Zhu)

Mayo Clinic

39H-index

73Paper Count

1.8WCitation Count

Published Papers 47

Publication Date

Senloytics, dasatinib plus quercetin, reduce kidney inflammation, senescent cell abundance, and injury while restoring geroprotective factors in murine diabetic kidney disease

eBioMedicine

IF10.8

2026-01-20

OAAI

Xiaohui Bian; Zachary K. Snow; Caroline J. Zinn; Anastasia L. Bratulin; Khaled M. Elhusseiny; Tamar Tchkonia; James L. Kirkland; Yi Zhu; Sundeep Khosla; Seo Rin Kim; Lilach O. Lerman; LaTonya J. Hickson

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Senolytic-Resistant Senescent Cells Have a Distinct SASP Profile and Functional Impact: The Path to Developing Senosensitizers

AGING CELL

IF7.1

2026-01-01

OAAI

Tripathi, Utkarsh; Suda, Masayoshi; Kulshreshtha, Vagisha; Piatkowski, Bryan T.; Palmer, Allyson K.; Giorgadze, Nino; Inman, Christina; Gasek, Nathan; Xu, Ming; Johnson, Kurt O.; Pirtskhalava, Tamar; Chaib, Selim; Langhi Prata, Larissa P. G.; Zhu, Yi; Kandhaya-pillai, Renuka; Tullius, Stefan G.; Wyles, Saranya P.; Majji, Rambabu; Yalamanchili, Hari Krishna; Allison, David B.; Tchkonia, Tamar; Kirkland, James L.

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Targeting KAT8 Alleviates Vascular Senescence by Modulating the INHBA/TGF-β Pathway

Molecular Therapy

IF12

2025-12-24

PREAI

Zhongxiao Lin; Jianyu Xiong; Fuyuan Zhang; Hao Zhang; Menglin Zhu; Caiyu Li; Rong Fu; Zhongyi Zhang; Qinwen Hu; Jie Liang; Bohan Fu; Chiyuan Ma; Kehan Jin; Liuyi Lu; Junmeng Zheng; Brian Tomlinson; Xi-Yong Yu; Yi Zhun Zhu

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Endoplasmic Reticulum-Targeting Natural Compounds: A Novel Frontier in Alleviating Liver Fibrosis

Drug Design; Development and Therapy

IF0

2025-12-23

OAAI

Chengrong Huang; Wei Hu; Jia Qi; Bolun Su; Hongrui Yan; Yi Zhun Zhu

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Endothelial senescent-cell-specific clearance alleviates metabolic dysfunction in obese mice

Cell Metabolism

IF30.9

2025-11-20

PREAI

Masayoshi Suda; Selim Chaib; Larissa G.P. Langhi Prata; Yi Zhu; Utkarsh Tripathi; Karl H. Paul; Allyson K. Palmer; Tamar Pirtskhalava; Vagisha Kulshreshtha; Christina L. Inman; Kurt O. Johnson; Nino Giorgadze; Runqing Huang; Carolyn M. Roos; Luisa F. Leon-Sanchez; Jordan D. Miller; Thomas White; Linshan Laux; Laura J. Niedernhofer; Paul D. Robbins

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In-situ injectable hydrogel for near-infrared-regulated hyperthermic perfusion therapy of triple-negative breast cancer

JOURNAL OF COLLOID AND INTERFACE SCIENCE

IF9.7

2025-07-01

PREAI

Zhai, Libin; Li, Linwei; Liao, Tao; Zhu, Yi; Li, Cao; Yu, Wenqian

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Carboxylic acid metabolism in cancer: Mechanisms, microenvironment interactions, and therapeutic opportunities

Metabolism

IF0

2025-06-26

PREAI

Xiqing Bian; Yue Zhuo; Luo Zhou; Yi Zhun Zhu; Na Li; Jian-Lin Wu

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Efficient cancer immunogenetherapy by tumor cell lysate modified mRNA formulation

Biomaterials

IF12.9

2025-06-02

PREAI

Jieping Wu; Xizi Fu; Xiaohua Chen; Ming Shuai; Mohan Liu; Jingmei Li; Yan Gao; Jin Zhang; Yi Zhun Zhu; Na Zhou; Ke Men; Xingmei Duan

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IL-2-loaded liposomes modified with sorafenib derivative exert a synergistic anti-melanoma effect via improving tumor immune microenvironment and enhancing antiangiogenic activity

ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES

IF11.9

2025-01-01

OAAI

Huang, Xuan; Kuerban, Kudelaidi; Fan, Jajun; Pan, Danjie; Chen, Huaning; Liu, Jiayang; Wang, Songna; Ju, Dianwen; Zhu, Yi Zhun; Liu, Jiyong; Ye, Li

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Bacterial Lysate-Based Bifunctional mRNA Nanoformulation for Efficient Colon Cancer Immunogene Therapy

ACS APPLIED MATERIALS & INTERFACES

IF8.2

2024-10-14

PREAI

Chen, Xiaohua; Wu, Jieping; Zhou, Bailing; Zhu, Manfang; Zhang, Jin; Zhou, Na; Zhu, Yi Zhun; Zhang, Xin; Duan, Xingmei; Men, Ke

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Past and Future Directions for Research on Cellular Senescence

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE

IF10.1

2023-09-21

PREAI

Zhu, Yi; Anastasiadis, Zacharias P.; Netto, Jair Machado Espindola; Evans, Tamara; Tchkonia, Tamar; Kirkland, James L.

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Senolytics combat COVID-19 in aging

NATURE AGING

IF19.4

2023-07-06

OAAI

Zhang, Xu; Suda, Masayoshi; Zhu, Yi

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Local senolysis in aged mice only partially replicates the benefits of systemic senolysis

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2023-04-17

OAAI

Farr, Joshua N.; Saul, Dominik; Doolittle, Madison L.; Kaur, Japneet; Rowsey, Jennifer L.; Vos, Stephanie J.; Froemming, Mitchell N.; Lagnado, Anthony B.; Zhu, Yi; Weivoda, Megan; Ikeno, Yuji; Pignolo, Robert J.; Niedernhofer, Laura J.; Robbins, Paul D.; Jurk, Diana; Passos, Joao F.; LeBrasseur, Nathan K.; Tchkonia, Tamara; Kirkland, James L.; Monroe, David G.; Khosla, Sundeep

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Rejuvenation of the aged brain immune cell landscape in mice through p16-positive senescent cell clearance

NATURE COMMUNICATIONS

IF15.7

2022-09-27

OAAI

Zhang, Xu; Pearsall, Vesselina M.; Carver, Chase M.; Atkinson, Elizabeth J.; Clarkson, Benjamin D. S.; Grund, Ethan M.; Baez-Faria, Michelle; Pavelko, Kevin D.; Kachergus, Jennifer M.; White, Thomas A.; Johnson, Renee K.; Malo, Courtney S.; Gonzalez-Suarez, Alan M.; Ayasoufi, Katayoun; Johnson, Kurt O.; Tritz, Zachariah P.; Fain, Cori E.; Khadka, Roman H.; Ogrodnik, Mikolaj; Jurk, Diana; Zhu, Yi; Tchkonia, Tamara; Revzin, Alexander; Kirkland, James L.; Johnson, Aaron J.; Howe, Charles L.; Thompson, E. Aubrey; LeBrasseur, Nathan K.; Schafer, Marissa J.

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Cellular senescence: a key therapeutic target in aging and diseases

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2022-08-01

223

OAAI

Zhang, Lei; Pitcher, Louise E.; Yousefzadeh, Matthew J.; Niedernhofer, Laura J.; Robbins, Paul D.; Zhu, Yi

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Orally-active, clinically-translatable senolytics restore a-Klotho in mice and humans

EBIOMEDICINE

IF10.8

2022-03-01

OAAI

Zhu, Yi; Prata, Larissa G. P. Langhi; Gerdes, Erin O. Wissler; Netto, Jair Machado Espindola; Pirtskhalava, Tamar; Giorgadze, Nino; Tripathi, Utkarsh; Inman, Christina L.; Johnson, Kurt O.; Xue, Ailing; Palmer, Allyson K.; Chen, Tingjun; Schaefer, Kalli; Justice, Jamie N.; Nambiar, Anoop M.; Musi, Nicolas; Kritchevsky, Stephen B.; Chen, Jun; Khosla, Sundeep; Jurk, Diana; Schafer, Marissa J.; Tchkonia, Tamar; Kirkland, James L.

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Selective Vulnerability of Senescent Glioblastoma Cells to BCL-XL Inhibition

MOLECULAR CANCER RESEARCH

IF4.7

2022-02-21

OAAI

Rahman, Masum; Olson, Ian; Mansour, Moustafa; Carlstrom, Lucas P.; Sutiwisesak, Rujapope; Saber, Rehan; Rajani, Karishma; Warrington, Arthur E.; Howard, Adam; Schroeder, Mark; Chen, Sisi; Decker, Paul A.; Sananikone, Eliot F.; Zhu, Yi; Tchkonia, Tamar; Parney, Ian F.; Burma, Sandeep; Brown, Desmond; Rodriguez, Moses; Sarkaria, Jann N.; Kirkland, James L.; Burns, Terry C.

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Development of a novel senolytic by precise disruption of FOXO4-p53 complex

EBIOMEDICINE

IF10.8

2021-12-01

OAAI

Tripathi, Utkarsh; Chaib, Selim; Gerdes, Erin O. Wissler; Hogan, Kelly A.; Zhu, Yi

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Assessment of the health status of middle-aged and elderly men with head scale, SF-36, IIEF5, AMS, and IPSS

BMC GERIATRICS

IF3.8

2021-11-12

OAAI

Zhu, Yi; Li, Jian-Hui; Zhao, Jing; Zheng, Jun-Biao; Liang, Qun-Feng; Yu, Xiao-Hua; Zhang, Shu-Cheng; Shi, Hui-Juan; Zhou, Wei-Jin; Zhu, Qian-Xi

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Fisetin for COVID-19 in skilled nursing facilities: Senolytic trials in the COVID era

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

IF4.5

2021-08-20

OAAI

Verdoorn, Brandon P.; Evans, Tamara K.; Hanson, Gregory J.; Zhu, Yi; Langhi Prata, Larissa G. P.; Pignolo, Robert J.; Atkinson, Elizabeth J.; Wissler-Gerdes, Erin O.; Kuchel, George A.; Mannick, Joan B.; Kritchevsky, Stephen B.; Khosla, Sundeep; Rizza, Stacey A.; Walston, Jeremy D.; Musi, Nicolas; Lipsitz, Lewis A.; Kiel, Douglas P.; Yung, Raymond; LeBrasseur, Nathan K.; Singh, Ravinder J.; McCarthy, Teresa; Puskarich, Michael A.; Niedernhofer, Laura J.; Robbins, Paul D.; Sorenson, Matthew; Tchkonia, Tamara; Kirkland, James L.

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Research Directions