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SaveShare Save Share Save Rational fragment-based design of compounds targeting the PWWP domain of the HRP family
Vantieghem, Thibault; Aslam, Nayyar A.; Osipov, Evgenii M.; Akele, Muluembet; Van Belle, Siska; Beelen, Steven; Drexler, Matus; Paulovcakova, Terezia; Lux, Vanda; Fearon, Daren; Douangamath, Alice; von Delft, Frank; Christ, Frauke; Veverka, Vaclav; Verwilst, Peter; Van Aerschot, Arthur; Debyser, Zeger; Strelkov, Sergei V. Share Save A dual role for PSIP1/LEDGF in T cell acute lymphoblastic leukemiaDemoen, Lisa; Matthijssens, Filip; Reunes, Lindy; Palhais, Bruno; Lintermans, Beatrice; T'Sas, Sara; Fijalkowski, Igor; Taminau, Joachim; Akele, Muluembet Z.; Van Belle, Siska; Taghon, Tom; Deforce, Dieter; Van Nieuwerburgh, Filip; Berx, Geert; Ntziachristos, Panagiotis; Debyser, Zeger; Durinck, Kaat; Pieters, Tim; Goossens, Steven; Van Vlierberghe, Pieter Share Save Prime editing functionally corrects cystic fibrosis-causing CFTR mutations in human organoids and airway epithelial cellsBulcaen, Mattijs; Kortleven, Pheline; Liu, Ronald B.; Maule, Giulia; Dreano, Elise; Kelly, Mairead; Ensinck, Marjolein M.; Thierie, Sam; Smits, Maxime; Ciciani, Matteo; Hatton, Aurelie; Chevalier, Benoit; Ramalho, Anabela S.; Solvas, Xavier Casadevall i; Debyser, Zeger; Vermeulen, Francois; Gijsbers, Rik; Sermet-Gaudelus, Isabelle; Cereseto, Anna; Carlon, Marianne S. Share Save Share Save Share Save Share Save Share Save BET-Independent Murine Leukemia Virus Integration Is Retargeted In Vivo and Selects Distinct Genomic Elements for LymphomagenesisNombela, Ivan; Michiels, Martine; Van Looveren, Dominique; Marcelis, Lukas; El Ashkar, Sara; Van Belle, Siska; Bruggemans, Anne; Tousseyn, Thomas; Schwaller, Jurg; Christ, Frauke; Gijsbers, Rik; De Rijck, Jan; Debyser, Zeger Share Save Share Save Share Save CRISPR/Cas9-Induced Mutagenesis Corroborates the Role of Transportin-SR2 in HIV-1 Nuclear ImportJanssens, Julie; Blokken, Jolien; Lampi, Yulia; De Wit, Flore; Bonisch, Irena Zurnic; Nombela, Ivan; Van de Velde, Paulien; Van Remoortel, Barbara; Gijsbers, Rik; Christ, Frauke; Debyser, Zeger Share Save Share Save Share Save Share Save Share Save Phage Display-Directed Discovery of LEDGF/p75 Binding Cyclic Peptide Inhibitors of HIV Replication (vol 20, pg 2064, 2012)Desimmie, Belete A.; Humbert, Michael; Lescrinier, Eveline; Hendrix, Jelle; Vets, Sofie; Gijsbers, Rik; Ruprecht, Ruth M.; Dietrich, Ursula; Debyser, Zeger; Christ, Frauke Share Save Unlike its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell SurvivalVan Belle, Siska; El Ashkar, Sara; Cermakova, Katerina; Matthijssens, Filip; Goossens, Steven; Canella, Alessandro; Hodges, Courtney H.; Christ, Frauke; De Rijck, Jan; Van Vlierberghe, Pieter; Veverka, Vaclav; Debyser, Zeger Share Save 
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