Not logged inAdjunct treatment with glycogen synthase (GYS1) antisense oligonucleotides with enzyme replacement therapy (ERT) reduces glycogen more effectively in the Pompe disease mouse model
Martin, Angela; Weiss, Lan; Carrer, Michele; Shmara, Alyaa; Boock, Victoria; Ibrahim, Matthew; Hettrick, Lisa; Watt, Andy; Jafar-nejad, Paymaan; Kimonis, Virginia .png)
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SaveShare Save Antisense oligonucleotide targeting glycogen synthase (GYS1) in a Pompe disease mouse modelKimonis, Virginia E.; Weiss, Lan; Carrer, Michele; Ta, Lac; Chang, Mindy; Cheng, Cheng; Hettrick, Lisa; Watt, Andy; Raben, Nina; Grossman, Tamar Share Save Discovery and characterization of AZD8701, a high affinity antisense oligonucleotide targeting FOXP3 to relieve immunosuppression in cancerSinclair, Charles; Revenko, Alexey S.; Johnson, R. B.; Peter, Alison; Taylor, Molly A.; Hettrick, Lisa A.; Klein, Stephanie; Solanki, Anisha; Chapman, Melissa; Yates, James; Angell, Helen K.; Watt, Andrew; Gattis, Danielle; Monia, Brett P.; Barry, Simon T.; Lyne, Paul; Edbrooke, Mark; Goldberg, Frederick; Macleod, A. R. Share Save Share Save High-affinity antisense oligonucleotides targeting Foxp3 inhibit immunosuppressive function of regulatory T-cells and produce antitumor effects in syngeneic tumor modelsSinclair, Charles; Revenko, Alexey S.; Peter, Alison; Johnson, Robert B.; Hettrick, Lisa A.; Taylor, Molly; Staniszewska, Anna; Hughes, Adina; Sandin, Lisa; Klein, Stephanie; Watt, Andrew; Barry, Simon; Monia, Brett T.; Lyne, Paul; Macleod, A. Robert; Edbrooke, Mark Share Save High-affinity antisense oligonucleotides targeting Foxp3 inhibit immunosuppressive function of regulatory T cells and produce anti-tumor effects in syngeneic tumor modelsRevenko, Alexey S.; Sinclair, Charles; Ben Johnson; Hettrick, Lisa; Peter, Alison; Staniszewska, Anna; Hughes, Adina; Sandin, Linda; Taylor, Molly; Klein, Stephanie; Watt, Andy; Monia, Brett; Edbrooke, Mark; MacLeod, A. Robert Share Save Share Save The role of biopharmaceutics in the development of a clinical nanoparticle formulation of MK-0869: a Beagle dog model predicts improved bioavailability and diminished food effect on absorption in humanWu, Y; Loper, A; Landis, E; Hettrick, L; Novak, L; Lynn, K; Chen, C; Thompson, K; Higgins, R; Batra, U; Shelukar, S; Kwei, G; Storey, D Share Save Share Save 
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