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A phase 1, open-label, dose-escalation study of PRT1419, a selective induced myeloid leukemia cell differentiation protein (MCL-1) inhibitor, in patients (pts) with advanced/metastatic solid tumors Falchook, Gerald; Patel, Manish; McKean, Meredith; Philipovskiy, Alexander; Chiaverelli, Rachel; Sun, William; Fossler, Michael; Novotny, William; Kurman, Michael; Rowe, Sarah; Hunter, Deborah; Milhem, Mohammed Share Save
Respiratory Effects of Biased Ligand Oliceridine in Older Volunteers: A Pharmacokinetic-Pharmacodynamic Comparison with Morphine Simons, Pieter; van der Schrier, Rutger; van Lemmen, Maarten; Jansen, Simone; Kuijpers, Kiki W. K.; van Velzen, Monique; Sarton, Elise; Nicklas, Todd; Michalsky, Cathy; Demitrack, Mark A.; Fossler, Michael; Olofsen, Erik; Niesters, Marieke; Dahan, Albert Share Save
The effect of TRV027 on coagulation in COVID-19: A pilot randomized, placebo-controlled trial Robbins, Alexander J.; Bakri, Nur Amalina Che; Toke-Bjolgerud, Edward; Edwards, Aaron; Vikraman, Asha; Michalsky, Cathy; Fossler, Michael; Lemm, Nana-Marie; Medhipour, Savviz; Budd, William; Gravani, Athanasia; Hurley, Lisa; Kapil, Vikas; Jackson, Aimee; Lonsdale, Dagan; Latham, Victoria; Laffan, Michael; Chapman, Neil; Cooper, Nichola; Szydlo, Richard; Boyle, Joseph; Pollock, Katrina M.; Owen, David Share Save
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A Phase I, Randomized, Single-Blind, Placebo-Controlled, Single Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of Subcutaneous and Oral TRV250, a G Protein-Selective Delta Receptor Agonist, in Healthy Subjects Fossler, Michael J.; Schmith, Virginia; Greene, Stephen A.; Lohmer, Lauren; Kramer, Michael S.; Arscott, Kelly; James, Ian E.; Demitrack, Mark A. Share Save
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Treatment of spontaneous preterm labour with retosiban: a phase II pilot dose-ranging study Thornton, Steven; Valenzuela, Guillermo; Baidoo, Charlotte; Fossler, Michael J.; Montague, Timothy H.; Clayton, Linda; Powell, Marcy; Snidow, Jerry; Stier, Brendt; Soergel, David Share Save
Maternofetal pharmacokinetics and fetal lung responses in chronically catheterized sheep receiving constant, low-dose infusions of betamethasone phosphate Kemp, Matthew W.; Saito, Masatoshi; Usuda, Haruo; Molloy, Timothy J.; Miura, Yuichiro; Sato, Shinichi; Watanabe, Shimpei; Clarke, Michael; Fossler, Michael; Scmidt, Augusto; Kallapur, Suhas G.; Kramer, Boris W.; Newnham, John P.; Jobe, Alan H. Share Save
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A Report from the Pediatric Formulations Task Force: Perspectives on the State of Child-Friendly Oral Dosage Forms Zajicek, Anne; Fossler, Michael J.; Barrett, Jeffrey S.; Worthington, Jeffrey H.; Ternik, Robert; Charkoftaki, Georgia; Lum, Susan; Breitkreutz, Joerg; Baltezor, Mike; Macheras, Panos; Khan, Mansoor; Agharkar, Shreeram; MacLaren, David Douglas Share Save
Safety, tolerability, pharmacokinetics and pharmacodynamics of losmapimod following a single intravenous or oral dose in healthy volunteers Barbour, April M.; Sarov-Blat, Lea; Cai, Gengqian; Fossler, Michael J.; Sprecher, Dennis L.; Graggaber, Johann; McGeoch, Adam T.; Maison, Jo; Cheriyan, Joseph Share Save
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