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J

John B. Mantyh

Duke University Medical Center

5H-index
36Paper Count
71Citation Count
Published Papers 7
Publication Date
Inhibition of cyclin-dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation
err2026-08-17
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errWylie K. Watlington; Divya L. Dayanidhi; Mohammad Zokaasadi; John B. Mantyh; Pelumi D. Olawuni; Gabrielle Rupprecht; Jeremy M. Force; Shannon McCall; Ashwani K. Bahl; David S. Hsu; Jason A. Somarelli
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Dual targeting of conserved cell cycle and transcription programs in advanced colorectal cancer by fadraciclib
err2025-01-01
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errZokaasadi, Mohammad; Watlington, Wylie K.; Dayanidhi, Divya L.; Mantyh, John B.; Rupprecht, Gabrielle; McCall, Shannon; Blake, David G.; Somarelli, Jason A.; Hsu, David S.
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Chromatin Remodeling in Patient-Derived Colorectal Cancer Models
err2024-02-21
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errXiang, Kun; Wang, Ergang; Mantyh, John; Rupprecht, Gabrielle; Negrete, Marcos; Sanati, Golshid; Hsu, Carolyn; Randon, Peggy; Dohlman, Anders; Kretzschmar, Kai; Bose, Shree; Giroux, Nicholas; Ding, Shengli; Wang, Lihua; Balcazar, Jorge Prado; Huang, Qiang; Sundaramoorthy, Pasupathi; Xi, Rui; Mccall, Shannon Jones; Wang, Zhaohui; Jiang, Chongming; Kang, Yubin; Kopetz, Scott; Crawford, Gregory E.; Lipkin, Steven M.; Wang, Xiao-Fan; Clevers, Hans; Hsu, David; Shen, Xiling
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Psymberin, a marine-derived natural product, induces cancer cell growth arrest and protein translation inhibition (vol 9, 999004, 2022)
err2023-05-31
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errDayanidhi, Divya L.; Somarelli, Jason A.; Mantyh, John B.; Rupprecht, Gabrielle; Roghani, Roham Salman; Vincoff, Sophia; Shin, Iljin; Zhao, Yiquan; Kim, So Young; McCall, Shannon; Hong, Jiyong; Hsu, David S.
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Protein Folding Stability Profiling of Colorectal Cancer Chemoresistance Identifies Functionally Relevant Biomarkers
err2023-05-01
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errQuan, Baiyi; Bailey, Morgan A.; Mantyh, John; Hsu, David S.; Fitzgerald, Michael C.
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Psymberin, a marine-derived natural product, induces cancer cell growth arrest and protein translation inhibition
err2022-12-20
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errDayanidhi, Divya L.; Somarelli, Jason A.; Mantyh, John B.; Rupprecht, Gabrielle; Roghani, Roham Salman; Vincoff, Sophia; Shin, Iljin; Zhao, Yiquan; Kim, So Young; McCall, Shannon; Hong, Jiyong; Hsu, David S.
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A Precision Medicine Drug Discovery Pipeline Identifies Combined CDK2 and 9 Inhibition as a Novel Therapeutic Strategy in Colorectal Cancer
err2020-12-02
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errSomarelli, Jason A.; Roghani, Roham Salman; Moghaddam, Ali Sanjari; Thomas, Beatrice C.; Rupprecht, Gabrielle; Ware, Kathryn E.; Altunel, Erdem; Mantyh, John B.; Kim, So Young; McCall, Shannon J.; Shen, Xiling; Mantyh, Christopher R.; Hsu, David S.
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