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Lipid-Based Self-Microemulsion of Niclosamide Achieved Enhanced Oral Delivery and Anti-Tumor Efficacy in Orthotopic Patient-Derived Xenograft of Hepatocellular Carcinoma in Mice Liu, Yi; Guerrero, David Quintanar; Lechuga-Ballesteros, David; Tan, Mingdian; Ahmad, Faiz; Aleiwi, Bilal; Ellsworth, Edmund Lee; Chen, Bin; Chua, Mei-Sze; So, Samuel Share Save
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Anti-fibrillization effects of sulfonamide derivatives on ?-synuclein and hyperphosphorylated tau isoform 1N4R Fortin, Jessica S.; Shimanaka, Kazuma; Saraswati, A. Prasanth; Liu, Mengyu; Wang, Kuan-Wei; Hagar, Hsiao-Tien; Maity, Soham; Ganegamage, Susantha K.; Ellsworth, Edmund; Counts, Scott E.; Borhan, Babak; Dettmer, Ulf; Kuo, Min-Hao Share Save
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Small Molecule 20S Proteasome Enhancer Regulates MYC Protein Stability and Exhibits Antitumor Activity in Multiple Myeloma Njomen, Evert; Vanecek, Allison; Lansdell, Theresa A.; Yang, Ya-Ting; Schall, Peter Z.; Harris, Christi M.; Bernard, Matthew P.; Isaac, Daniel; Alkharabsheh, Omar; Al-Janadi, Anas; Giletto, Matthew B.; Ellsworth, Edmund; Taylor, Catherine; Tang, Terence; Lau, Sarah; Bailie, Marc; Bernard, Jamie J.; Yuzbasiyan-Gurkan, Vilma; Tepe, Jetze J. Share Save
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The novel rexinoid MSU-42011 is effective for the treatment of preclinical Kras-driven lung cancer Moerland, Jessica A.; Zhang, Di; Reich, Lyndsey A.; Carapellucci, Sarah; Lockwood, Beth; Leal, Ana S.; Krieger-Burke, Teresa; Aleiwi, Bilal; Ellsworth, Edmund; Liby, Karen T. Share Save
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Identification of New MmpL3 Inhibitors by Untargeted and Targeted Mutant Screens Defines MmpL3 Domains with Differential Resistance Williams, John T.; Haiderer, Elizabeth R.; Coulson, Garry B.; Conner, Kayla N.; Ellsworth, Edmund; Chen, Chao; Alvarez-Cabrera, Nadine; Li, Wei; Jackson, Mary; Dick, Thomas; Abramovitch, Robert B. Share Save
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Stereoselective Synthesis of (S)-3-(Methylamino)-3-((R)-pyrrolidin-3-yl)propanenitrile Lall, Manjinder S.; Hoge, Garrett; Tran, Tuan P.; Kissel, William; Murphy, Sean T.; Taylor, Clarke; Hutchings, Kim; Samas, Brian; Ellsworth, Edmund L.; Curran, Timothy; Showalter, H. D. Hollis Share Save
In vitro and in vivo activities of PD 0305970 and PD 0326448, new bacterial gyrase/topoisomerase inhibitors with potent antibacterial activities versus multidrug-resistant gram-positive and fastidious organism groups Huband, Michael D.; Cohen, Michael A.; Zurack, Margaret; Hanna, Debra L.; Skerlos, Laura A.; Sulavik, Mark C.; Gibson, Glenn W.; Gage, Jeffrey W.; Ellsworth, Edmund; Stier, Michael A.; Gracheck, Stephen J. Share Save
3-aminoquinazolinediones as a new class of antibacterial agents demonstrating excellent antibacterial activity against wild-type and multidrug resistant organisms Ellsworth, Edmund L.; Tran, Tuan P.; Showalter, H. D. Hollis; Sanchez, Joseph P.; Watson, Brian M.; Stier, Michael A.; Domagala, John M.; Gracheck, Stephen J.; Joannides, E. Themis; Shapiro, Martin A.; Dunham, Steve A.; Hanna, Debra L.; Huband, Michael D.; Gage, Jeffrey W.; Bronstein, Joel C.; Liu, Jia Yeu; Nguyen, Dai Q.; Singh, Rajeshwar Share Save
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