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Case Studies for Overcoming Challenges in Using Big Data in Cancer Sweeney, Shawn M.; Hamadeh, Hisham K.; Abrams, Natalie; Adam, Stacey J.; Brenner, Sara; Connors, Dana E.; Davis, Gerard J.; Fiore, Louis D.; Gawel, Susan H.; Grossman, Robert L.; Hanlon, Sean E.; Hsu, Karl; Kelloff, Gary J.; Kirsch, Ilan R.; Louv, Bill; McGraw, Deven; Meng, Frank; Milgram, Daniel; Miller, Robert S.; Morgan, Emily; Mukundam, Lata; O'Brien, Thoma; Robbins, Paul; Rubin, Eric H.; Rubinstein, Wendy S.; Salmi, Liz; Schaller, Teilo H.; Shi, George; Sigman, Caroline C.; Srivastava, Sudhir Share Save
Challenges to Using Big Data in Cancer Sweeney, Shawn M.; Hamadeh, Hisham K.; Abrams, Natalie; Adam, Stacey J.; Brenner, Sara; Connors, Dana E.; Davis, Gerard J.; Fiore, Louis; Gawel, Susan H.; Grossman, Robert L.; Hanlon, Sean E.; Hsu, Karl; Kelloff, Gary J.; Kirsch, Ilan R.; Louv, Bill; McGraw, Deven; Meng, Frank; Milgram, Daniel; Miller, Robert S.; Morgan, Emily; Mukundan, Lata; O'Brien, Thomas; Robbins, Paul; Rubin, Eric H.; Rubinstein, Wendy S.; Salmi, Liz; Schaller, Teilo; Shi, George; Sigman, Caroline C.; Srivastava, Sudhir Share Save
Real-world prevalence across 159 872 patients with cancer supports the clinical utility of TMB-H to define metastatic solid tumors for treatment with pembrolizumab Fabrizio, D.; Cristescu, R.; Albacker, L.; Snyder, A.; Ward, A.; Lunceford, J.; Aurora-Garg, D.; Jin, F.; Hopkins, J.; Rubin, E.; Hegde, P. Share Save
The topoisomerase I- and p53-binding protein topors is differentially expressed in normal and malignant human tissues and may function as a tumor suppressor (vol 23, pg 5293, 2004) Saleem, Ahamed; Dutta, Jayeeta; Malegaonkar, Diptee; Rasheed, Farheena; Rasheed, Zeshaan; Rajendra, Rajeev; Marshall, Henderson; Luo, Minjie; Li, Honghua; Rubin, Eric H. Share Save
Seamless Designs: Current Practice and Considerations for Early-Phase Drug Development in Oncology Hobbs, Brian P.; Barata, Pedro C.; Kanjanapan, Yada; Paller, Channing J.; Perlmutter, Jane; Pond, Gregory R.; Prowell, Tatiana M.; Rubin, Eric H.; Seymour, Lesley K.; Wages, Nolan A.; Yap, Timothy A.; Feltquate, David; Garrett-Mayer, Elizabeth; Grossman, William; Hong, David S.; Ivy, S. Percy; Siu, Lillian L.; Reeves, Steven A.; Rosner, Gary L. Share Save
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Informing the Tolerability of Cancer Treatments Using Patient-Reported Outcome Measures: Summary of an FDA and Critical Path Institute Workshop Kluetz, Paul G.; Kanapuru, Bindu; Lemery, Steven; Johnson, Laura Lee; Fiero, Mallorie H.; Arscott, Karen; Barbachano, Yolanda; Basch, Ethan; Campbell, Michelle; Cappelleri, Joseph C.; Cella, David; Cleeland, Charles; Coens, Corneel; Daniels, Selena; Denlinger, Crystal S.; Fairclough, Dianne L.; Hillard, James R.; Minasian, Lori; Mitchell, Sandra A.; O'Connor, Daniel; Patel, Sheetal; Rubin, Eric H.; Ryden, Anna; Soltys, Katherine; Sridhara, Rajeshwari; Thanarajasingam, Gita; Velikova, Galina; Coons, Stephen Joel Share Save
Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors Moschos, Stergios J.; Sullivan, Ryan J.; Hwu, Wen-Jen; Ramanathan, Ramesh K.; Adjei, Alex A.; Fong, Peter C.; Shapira-Frommer, Ronnie; Tawbi, Hussein A.; Rubino, Joseph; Rush, Thomas S., III; Zhang, Da; Miselis, Nathan R.; Samatar, Ahmed A.; Chun, Patrick; Rubin, Eric H.; Schiller, James; Long, Brian J.; Dayananth, Priya; Carr, Donna; Kirschmeier, Paul; Bishop, W. Robert; Deng, Yongqi; Cooper, Alan; Shipps, Gerald W.; Moreno, Blanca Homet; Robert, Lidia; Ribas, Antoni; Flaherty, Keith T. Share Save
Seamless phase I/II clinical trials in oncology: retrospective analysis of the last 7 years Barata, Pedro; Hobbs, Brian; Rini, Brian; Paller, Channing; Normolle, Dan; Garrett-Mayer, Elizabeth; Rubin, Eric; Rosner, Gary; Pond, Greg; Perlmutter, Jane; Seymour, Lesley; Siu, Lillian; Wages, Nolan; Ivy, Percy; Prowell, Tatiana; Yap, Timothy; Hong, David Share Save
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Abscopal effect in a Hodgkin lymphoma patient treated by an anti-programmed death 1 antibody Michot, Jean-Marie; Mazeron, Renaud; Dercle, Laurent; Ammari, Samy; Canova, Charles; Marabelle, Aurelien; Rose, Shelonitda; Rubin, Eric; Deutsch, Eric; Soria, Jean-Charles; Ribrag, Vincent; Levy, Antonin Share Save
Phase I/IIa trial of the mammalian target of rapamycin inhibitor ridaforolimus (AP23573; MK-8669) administered orally in patients with refractory or advanced malignancies and sarcoma Mita, M. M.; Poplin, E.; Britten, C. D.; Tap, W. D.; Rubin, E. H.; Scott, B. B.; Berk, L.; Rivera, V. M.; Loewy, J. W.; Dodion, P.; Haluska, F.; Sarantopoulos, J.; Mita, A.; Tolcher, A. Share Save
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A phase 1 trial of E7974 administered on day 1 of a 21-day cycle in patients with advanced solid tumors Rocha-Lima, Caio M.; Bayraktar, Soley; MacIntyre, Jessica; Raez, Luis; Flores, Aurea M.; Ferrell, Annapoorna; Rubin, Eric H.; Poplin, Elizabeth A.; Tan, Antoinette R.; Lucarelli, Antonio; Zojwalla, Naseem Share Save
MK-2206, a Novel Allosteric Inhibitor of Akt, Synergizes with Gefitinib against Malignant Glioma via Modulating Both Autophagy and Apoptosis Cheng, Yan; Zhang, Yi; Zhang, Li; Ren, Xingcong; Huber-Keener, Kathryn J.; Liu, Xiaoyuan; Zhou, Lei; Liao, Jason; Keihack, Heike; Yan, Li; Rubin, Eric; Yang, Jin-Ming Share Save
Rationally Designed Treatment for Solid Tumors with MAPK Pathway Activation: A Phase I Study of Paclitaxel and Bortezomib Using an Adaptive Dose-Finding Approach Mehnert, Janice M.; Tan, Antoinette R.; Moss, Rebecca; Poplin, Elizabeth; Stein, Mark N.; Sovak, Mika; Levinson, Kelly; Lin, Hongxia; Kane, Michael; Gounder, Murugesan; Lin, Yong; Shih, Weichung Joe; White, Eileen; Rubin, Eric H.; Karantza, Vassiliki Share Save
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