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Velcrin molecular glues induce apoptosis in glioblastomas with high PDE3A and SLFN12 expression Aquilanti, Elisa; Goldoni, Silvia; Baker, Andrew; Kotynkova, Kristyna; Andersen, Sawyer; Bozinov, Vincent; Gao, Galen F.; Cherniack, Andrew D.; Lange, Martin; Lesche, Ralf; Kopitz, Charlotte; Lienau, Philip; Lewis, Timothy A.; Garrido, Marine; Gradl, Stefan; Seidel, Henrik; Tseng, Yuen-Yi; Ligon, Keith L.; Wen, Patrick Y.; Meyerson, Matthew; Greulich, Heidi Share Save
Targeting TRIP13 in favorable histology Wilms tumor with nuclear export inhibitors synergizes with doxorubicin Mittal, Karuna; Cooper, Garrett W.; Lee, Benjamin P.; Su, Yongdong; Skinner, Katie T.; Shim, Jenny; Jonus, Hunter C.; Kim, Won Jun; Doshi, Mihir; Almanza, Diego; Kynnap, Bryan D.; Christie, Amanda L.; Yang, Xiaoping; Cowley, Glenn S.; Leeper, Brittaney A.; Morton, Christopher L.; Dwivedi, Bhakti; Lawrence, Taylor; Rupji, Manali; Keskula, Paula; Meyer, Stephanie; Clinton, Catherine M.; Bhasin, Manoj; Crompton, Brian D.; Tseng, Yuen-Yi; Bohm, Jesse S.; Ligon, Keith L.; Root, David E.; Murphy, Andrew J.; Weinstock, David M.; Gokhale, Prafulla C.; Spangle, Jennifer M.; Rivera, Miguel N.; Mullen, Elizabeth A.; Stegmaier, Kimberly; Goldsmith, Kelly C.; Hahn, William C.; Hong, Andrew L. Share Save
Charting ovarian cancer dependencies with patient-derived organoids Anderson, Ashley; Bertea, Tate; Neiswender, James; Brenan, Lisa; Wong, Megan; Simerzin, Alina; Wie, Sarah; Boyle, Isabella; Golden, Lauren; De Kegel, Barbara; Dempster, Josh; Tseng, Yuen-Yi; Root, David; Hill, Sarah; Aguirre, Andrew; Vazquez, Francisca Share Save
Systematic profiling of conditional pathway activation identifies context-dependent synthetic lethalities (vol 55, pg 1709, 2023) Chang, Liang; Jung, Nancy Y.; Atari, Adel; Rodriguez, Diego J.; Kesar, Devishi; Song, Tian-Yu; Rees, Matthew G.; Ronan, Melissa; Li, Ruitong; Ruiz, Paloma; Chaturantabut, Saireudee; Ito, Takahiro; van Tienen, Laurens M.; Tseng, Yuen-Yi; Roth, Jennifer A.; Sellers, William R. Share Save
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Systematic profiling of conditional pathway activation identifies context-dependent synthetic lethalities Chang, Liang; Jung, Nancy Y.; Atari, Adel; Rodriguez, Diego J.; Kesar, Devishi; Song, Tian-Yu; Rees, Matthew G.; Ronan, Melissa; Li, Ruitong; Ruiz, Paloma; Chaturantabut, Saireudee; Ito, Takahiro; van Tienen, Laurens M.; Tseng, Yuen-Yi; Roth, Jennifer A.; Sellers, William R. Share Save
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Charting new cancer dependencies with patient derived organoids Neiswender, James V.; Brenan, Lisa; Bertea, Tate; Guo, Jimmy; Anderson, Ashley; Wong, Megan; Posner, Zoe; Kapner, Kevin; Hennessey, Connor; Wie, Sarah; Boyle, Isabella; De Kegel, Barbara; Dempster, Joshua; Tseng, Yuen-Yi (Moony); Root, David; Aguirre, Andrew; Vazquez, Francisca Share Save
CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity Joung, Julia; Kirchgatterer, Paul C.; Singh, Ankita; Cho, Jang H.; Nety, Suchita P.; Larson, Rebecca C.; Macrae, Rhiannon K.; Deasy, Rebecca; Tseng, Yuen-Yi; Maus, Marcela, V; Zhang, Feng Share Save
Cancer Cell Line Factory: A systematic approach to create next-generation cancer model at scale Tseng, Yuen-Yi; Al-Jazrawe, Mushriq; Deasy, Rebecca; Keskula, Paula; Johnson, Grace; Hong, Andrew; Chatterji, Priya; Vasquez, Francisca; Bass, Adam; Van Hare, Barbara; Sandak, David; Ligon, Keith; Boehm, Jesse Share Save
A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis Zou, Yilong; Palte, Michael J.; Deik, Amy A.; Li, Haoxin; Eaton, John K.; Wang, Wenyu; Tseng, Yuen-Yi; Deasy, Rebecca; Kost-Alimova, Maria; Dancik, Vlado; Leshchiner, Elizaveta S.; Viswanathan, Vasanthi S.; Signoretti, Sabina; Choueiri, Toni K.; Boehm, Jesse S.; Wagner, Bridget K.; Doench, John G.; Clish, Clary B.; Clemons, Paul A.; Schreiber, Stuart L. Share Save
Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition Hong, Andrew L.; Tseng, Yuen-Yi; Wala, Jeremiah A.; Kim, Won-Jun; Kynnap, Bryan D.; Doshi, Mihir B.; Kugener, Guillaume; Sandoval, Gabriel J.; Howard, Thomas P.; Li, Ji; Yang, Xiaoping; Tillgren, Michelle; Ghandi, Mahmhoud; Sayeed, Abeer; Deasy, Rebecca; Ward, Abigail; McSteen, Brian; Labella, Katherine M.; Keskula, Paula; Tracy, Adam; Connor, Cora; Clinton, Catherine M.; Church, Alanna J.; Crompton, Brian D.; Janeway, Katherine A.; Van Hare, Barbara; Sandak, David; Gjoerup, Ole; Bandopadhayay, Pratiti; Clemons, Paul A.; Schreiber, Stuart L.; Root, David E.; Gokhale, Prafulla C.; Chi, Susan N.; Mullen, Elizabeth A.; Roberts, Charles W. M.; Kadoch, Cigall; Beroukhim, Rameen; Ligon, Keith L.; Boehm, Jesse S.; Hahn, William C. Share Save
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Modeling renal medullary carcinomas identifies druggable vulnerabilities in SMARCB1-deficient cancers Hong, Andrew L.; Tseng, Yuen-Yi; Kynnap, Bryan D.; Doshi, Mihir B.; Wala, Jeremiah; Sandoval, Gabriel; Church, Alanna J.; Mullen, Elizabeth; Kadoch, Cigall; Roberts, Charles W. M.; Beroukhim, Rameen; Boehm, Jesse S.; Hahn, William C. Share Save
Patient-derived xenografts undergo mouse-specific tumor evolution Ben-David, Uri; Ha, Gavin; Tseng, Yuen-Yi; Greenwald, Noah F.; Oh, Coyin; Shih, Juliann; McFarland, James M.; Wong, Bang; Boehm, Jesse S.; Beroukhim, Rameen; Golub, Todd R. Share Save
Patient-derived xenografts undergo mouse-specific tumor evolution Ben-David, Uri; Ha, Gavin; Tseng, Yuen-Yi; Greenwald, Noah F.; Oh, Coyin; Shih, Juliann; McFarland, James M.; Wong, Bang; Boehm, Jesse S.; Beroukhim, Rameen; Golub, Todd R. Share Save
Identification of Druggable Targets through Functional Multi-Omics in Renal Medullary Carcinoma Hong, Andrew L.; Tseng, Yuen-Yi; Kynnap, Bryan D.; Doshi, Mihir B.; Sandoval, Gabriel; Oh, Coyin; Sayeed, Abeer; Shubhroz, Gill; Church, Alanna J.; Keskula, Paula; Peng, Anson; Clemons, Paul A.; Tsherniak, Aviad; Vazquez, Francisca; Rodriguez-Galindo, Carlos; Janeway, Katherine A.; Garraway, Levi A.; Schreiber, Stuart L.; Root, David E.; Mullen, Elizabeth; Stegmaier, Kimberly; Kadoch, Cigall; Roberts, Charles W. M.; Boehm, Jesse S.; Hahn, William C. Share Save
Accelerating prediction of pediatric and rare cancer vulnerabilities using next-generation cancer models Tseng, Yuen-Yi; Hong, Andrew; Keskula, Paula; Gill, Shubhroz; Cheah, Jaime; Kryukov, Grigoriy; Tsherniak, Aviad; Vazquez, Francisca; Cowley, Glenn; Alkhairy, Sahar; Oh, Coyin; Peng, Anson; Deasy, Rebecca; Sayeed, Abeer; Ronning, Peter; Ng, Samuel; Corsello, Steven; Painter, Corrie; Sandak, David; Garraway, Levi; Rubin, Mark; Kuo, Calvin; Puram, Sidharth; Weinstock, David; Bass, Adam; Wagle, Nikhil; Ligon, Keith; Janeway, Katherine; Root, David; Schreiber, Stuart; Clemons, Paul; Shamji, Aly; Shamji, Aly; Hahn, William; Golub, Todd; Boehm, Jesse Share Save
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