Not logged in Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer Dilly, Julien; Hoffman, Megan T.; Abbassi, Laleh; Li, Ziyue; Paradiso, Francesca; Parent, Brendan D.; Hennessey, Connor J.; Jordan, Alexander C.; Morgado, Micaela; Dasgupta, Shatavisha; Uribe, Giselle A.; Yang, Annan; Kapner, Kevin S.; Hambitzer, Felix P.; Qiang, Li; Feng, Hanrong; Geisberg, Jacob; Wang, Junning; Evans, Kyle E.; Lyu, Hengyu; Schalck, Aislyn; Feng, Ningping; Lopez, Anastasia M.; Bristow, Christopher A.; Kim, Michael P.; Rajapakshe, Kimal I.; Bahrambeigi, Vahid; Roth, Jennifer A.; Garg, Kavita; Guerrero, Paola A.; Stanger, Ben Z.; Cristea, Simona; Lowe, Scott W.; Baslan, Timour; Van Allen, Eliezer M.; Mancias, Joseph D.; Chan, Emily; Anderson, Abraham; Katlinskaya, Yuliya V.; Shalek, Alex K.; Hong, David S.; Pant, Shubham; Hallin, Jill; Anderes, Kenna; Olson, Peter; Heffernan, Timothy P.; Chugh, Seema; Christensen, James G.; Maitra, Anirban; Wolpin, Brian M.; Raghavan, Srivatsan; Nowak, Jonathan A.; Winter, Peter S.; Dougan, Stephanie K.; Aguirre, Andrew J. Share Save
Efficacy and Safety of Adagrasib plus Cetuximab in Patients with KRASG12C-Mutated Metastatic Colorectal Cancer Yaeger, Rona; Uboha, Nataliya V.; Pelster, Meredith S.; Bekaii-Saab, Tanios S.; Barve, Minal; Saltzman, Joel; Sabari, Joshua K.; Peguero, Julio A.; Paulson, Andrew Scott; Janne, Pasi A.; Cruz-Correa, Marcia; Anderes, Kenna; Velastegui, Karen; Yan, Xiaohong; Der-Torossian, Hirak; Klempner, Samuel J.; Kopetz, Scott E. Share Save
Effects of adagrasib on cholesterol, lipid and glucose gene expression regulation in tumor xenograft models and patient samples Shelton, Fabiola; Hoffman, Natalie; Trinh, David; Helu, Xousaen M.; Calinisan, Andrew; Hebbert, Allan; Yan, Larry; Briere, David M.; Hover, Laura; Fernandez-Benet, Julio; Anderes, Kenna; Christensen, James G.; Hallin, Jill; Olson, Peter Share Save
Adagrasib with or without cetuximab in patients with KRASG12C-mutated colorectal cancer (CRC): Analysis of tumor biomarkers and genomic alterations Pelster, M. S.; Yaeger, R.; Klempner, S. J.; Ou, S-H. I.; Spira, A. I.; Janne, P. A.; Uboha, N. V.; Gaffar, Y. A.; Newman, G.; Paweletz, C. P.; Heavey, G. A.; Alejandro, L.; Kheoh, T.; Anderes, K.; Torossian, H. Der; Christensen, J. G.; Weiss, J. Share Save
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Molecular Characterization of Acquired Resistance to KRAS G12C-EGFR Inhibition in Colorectal Cancer Yaeger, Rona; Mezzadra, Riccardo; Sinopoli, Jenna; Bian, Yu; Marasco, Michelangelo; Kaplun, Esther; Gao, Yijun; Zhao, HuiYong; Paula, Arnaud Da Cruz; Zhu, Yingjie; Perez, Almudena Chaves; Chadalavada, Kalyani; Tse, Edison; Chowdhry, Sudhir; Bowker, Sydney; Chang, Qing; Qeriqi, Besnik; Weigelt, Britta; Nanjangud, Gouri J.; Berger, Michael F.; Der-Torossian, Hirak; Anderes, Kenna; Socci, Nicholas D.; Shia, Jinru; Murciano-Goroff, Yonina R.; Li, Bob; Christensen, James G.; Reis-Filho, Jorge S.; Solit, David B.; de Stanchina, Elisa; Lowe, Scott W.; Rosen, Neal; Misale, Sandra Share Save
Adagrasib in Non-Small-Cell Lung Cancer Harboring a KRASG12C Mutation Jaenne, Pasi A.; Riely, Gregory J.; Gadgeel, Shirish M.; Heist, Rebecca S.; Ou, Sai-Hong I.; Pacheco, Jose M.; Johnson, Melissa L.; Sabari, Joshua K.; Leventakos, Konstantinos; Yau, Edwin; Bazhenova, Lyudmila; Negrao, Marcelo V.; Pennell, Nathan A.; Zhang, Jun; Anderes, Kenna; Der-Torossian, Hirak; Kheoh, Thian; Velastegui, Karen; Yan, Xiaohong; Christensen, James G.; Chao, Richard C.; Spira, Alexander I. Share Save
Pharmacodynamic evidence for WEE1 target engagement in surrogate and tumor tissues from a phase I study of the WEE1 inhibitor ZN-c3 Chalasani, P.; Tolcher, A.; Meric-Bernstam, F.; Mamdani, H.; de Jong, P. R.; Anderes, K.; Samatar, A. A.; Sergeeva, M.; Gazdoiu, M.; Viana, M. R.; Pultar, P.; Voliotis, D.; Donate, F. Share Save
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Inhibition of RNA Polymerase I as a therapeutic strategy for cancer-specific activation of p53 Bywater, Megan J.; Anderes, Kenna; Huser, Nanni; Proffitt, Chris; Bleisath, Joshua; Haddach, Mustapha; Schwaebe, Michael; Ryckman, David; Rice, William G.; Lowe, Scott W.; Johnstone, Ricky W.; Poortinga, Gretchen; Pearson, Richard B.; McArthur, Grant A.; Hannan, Ross D.; Sanij, Elaine; Hein, Nadine; Peck, Abigail; Cullinane, Carleen; Wall, Meaghan; Cluse, Leonie; Drygin, Denis Share Save
CK2 inhibitor CX-4945 modulates AKT, NF-kB, TP53 and MEK inhibitor PD-325901 targets AP1 mediated CK2 inhibitor drug resistance in head and neck cancer Bian, Yansong; Han, Jiawei; Kannabiran, Vishnu; Mohan, Suresh; Friedman, Jay; Anderes, Kenna; Chen, Zhong; Van Waes, Carter Share Save
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Dual Inhibition of the Vascular Endothelial Growth Factor Pathway Hong, David S.; Garrido-Laguna, Ignacio; Ekmekcioglu, Suhendan; Falchook, Gerald S.; Naing, Aung; Wheler, Jennifer J.; Fu, Siqing; Moulder, Stacy L.; Piha-Paul, Sarina; Tsimberidou, Apostolia M.; Wen, YueJin; Culotta, Kirk S.; Anderes, Kenna; Davis, Darren W.; Liu, Wen; George, Goldy C.; Camacho, Luis H.; Ivy, Susan Percy; Kurzrock, Razelle Share Save
Characterization and identification of specific EGFR mutations in circulating tumor cells (CTCs) isolated from non-small cell lung cancer patients using an antibody independent method, ApoStream™: An update report. Tran, Hai T.; Melnikova, Vladislava; Tsao, Anne S.; Fossella, Frank V.; Johnson, Faye M.; Papadimitrakoupoulou, Vali; Richardson, Katherine; Lewis, Marcia E.; Legendre, Ben; Anderes, Kenna L.; Davis, Darren W.; Heymach, John V. Share Save
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Androgen Receptor Expression in in Circulating Tumor Cells, Archival and Metastatic Tissue in Prostate Cancer Patients Anderes, K.; Melnikova, V.; Pace, M.; Sukumaran, S.; Garza, M.; Redden, B.; Woo, J.; Davis, D.; Amato, R. Share Save
Combined inhibition of EGFR and CK2 augments the attenuation of PI3K-Akt-mTOR signaling and the killing of cancer cells Bliesath, Joshua; Huser, Nanni; Omori, Mayuko; Bunag, Daniel; Proffitt, Chris; Streiner, Nicole; Ho, Caroline; Siddiqui-Jain, Adam; O'Brien, Sean E.; Lim, John K. C.; Ryckman, David M.; Anderes, Kenna; Rice, William G.; Drygin, Denis Share Save
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Discovery of CX-5461, the First Direct and Selective Inhibitor of RNA Polymerase I, for Cancer Therapeutics Haddach, Mustapha; Schwaebe, Michael K.; Michaux, Jerome; Nagasawa, Johnny; O'Brien, Sean E.; Whitten, Jeffrey P.; Pierre, Fabrice; Kerdoncuff, Pauline; Darjania, Levan; Stansfield, Ryan; Drygin, Denis; Anderes, Kenna; Proffitt, Chris; Bliesath, Josh; Siddiqui-Jain, Adam; Omori, May; Huser, Nanni; Rice, William G.; Ryckman, David M. Share Save
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