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GenePHIT phase 2 study design: a double blind, placebo-controlled trial to assess efficacy, safety, and tolerability of AB-1002 gene therapy in adults with heart failure Henry, T.; Chung, E. S.; Alvisi, M.; Sethna, F.; Roessig, L.; Roberts, L.; Reddy, S.; Ervin, L.; Mikhail, S.; Jiang, C.; Samulski, J.; Kranias, E. G.; Tretiakova, A.; Hajjar, R. J. Share Save
A novel role for phospholamban in the thalamic reticular nucleus Klocke, Benjamin; Britzolaki, Aikaterini; Saurine, Joseph; Ott, Hayden; Krone, Kylie; Bahamonde, Kiara; Thelen, Connor; Tzimas, Christos; Sanoudou, Despina; Kranias, Evangelia G.; Pitychoutis, Pothitos M. Share Save
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Type 1 phosphatase, a negative regulator of cardiac function Carr, AN; Schmidt, AG; Suzuki, Y; del Monte, F; Sato, Y; Lanner, C; Breeden, K; Jing, SL; Allen, PB; Greengard, P; Yatani, A; Hoit, BD; Grupp, IL; Hajjar, RJ; DePaoli-Roach, AA; Kranias, EG Share Save
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Isoform changes of action potential regulators in the ventricles of arrhythmogenic phospholamban-R14del humanized mouse hearts Rogalska, Malgorzata E.; Vafiadaki, Elizabeth; Erpapazoglou, Zoi; Haghighi, Kobra; Green, Lisa; Mantzoros, Christos S.; Hajjar, Roger J.; Tranter, Michael; Karakikes, Ioannis; Kranias, Evangelia G.; Stillitano, Francesca; Kafasla, Panagiota; Sanoudou, Despina Share Save
A first-in-human phase 1 clinical gene therapy trial for the treatment of heart failure using a novel rationally designed cardiotropic adeno-associated vector Alvisi, Monica; Henry, Timothy; Chung, Eugene; Traverse, Jay; Ervin, Leigh; Krupa, Shiva; Sadek, Hesham; Jiang, Canwen; Mikhail, Sheila; Haghighi, Kobra; Kranias, Evangelia; Samulski, Jude; Tretalova, Anna; Hajjar, Roger Share Save
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Arrhythmia Mechanism and Dynamics in a Humanized Mouse Model of Inherited Cardiomyopathy Caused by Phospholamban R14del Mutation Raad, Nour; Bittihn, Philip; Cacheux, Marine; Jeong, Dongtak; Ilkan, Zeki; Ceholski, Delaine; Kohlbrenner, Erik; Zhang, Lu; Cai, Chen-Leng; Kranias, Evangelia G.; Hajjar, Roger J.; Stillitano, Francesca; Akar, Fadi G. Share Save
Impaired Right Ventricular Calcium Cycling Is an Early Risk Factor in R14del-Phospholamban Arrhythmias Haghighi, Kobra; Gardner, George; Vafiadaki, Elizabeth; Kumar, Mohit; Green, Lisa C.; Ma, Jianyong; Crocker, Jeffrey S.; Koch, Sheryl; Arvanitis, Demetrios A.; Bidwell, Phillip; Rubinstein, Jack; van de Leur, Rutger; Doevendans, Pieter A.; Akar, Fadi G.; Tranter, Michael; Wang, Hong-Sheng; Sadayappan, Sakthivel; DeMazumder, Deeptankar; Sanoudou, Despina; Hajjar, Roger J.; Stillitano, Francesca; Kranias, Evangelia G. Share Save
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Determinants of Ca2+ release restitution: Insights from genetically altered animals and mathematical modeling Cely-Ortiz, Alejandra; Felice, Juan, I; Diaz-Zegarra, Leandro A.; Valverde, Carlos A.; Federico, Marilen; Palomeque, Julieta; Wehrens, Xander H. T.; Kranias, Evangelia G.; Aiello, Ernesto A.; Lascano, Elena C.; Negroni, Jorge A.; Mattiazzi, Alicia Share Save
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Mechanisms Underlying Phospholamban L39 Stop (PLN L39X) Cardiomyopathy Bailey, Rasheed A.; Stillitano, Francesca; Turnbull, Irene; Haghigi, Kobra; Fish, Kenneth; Akar, Fadi; Dubois, Nicole; Wickramasinghe, Nadeera; Hajjar, Roger J.; Gelb, Bruce D.; Costa, Kevin D.; Kranias, Evangelia; Triveri, MariaGiovanna Share Save
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Modifications of Sarcoplasmic Reticulum Function Prevent Progression of Sarcomere-Linked Hypertrophic Cardiomyopathy Despite a Persistent Increase in Myofilament Calcium Response Chowdhury, Shamim A. K.; Warren, Chad M.; Simon, Jillian N.; Ryba, David M.; Batra, Ashley; Varga, Peter; Kranias, Evangelia G.; Tardiff, Jil C.; Solaro, R. John; Wolska, Beata M. Share Save
Tumor susceptibility gene 101 ameliorates endotoxin-induced cardiac dysfunction by enhancing Parkin-mediated mitophagy Essandoh, Kobina; Wang, Xiaohong; Huang, Wei; Deng, Shan; Gardner, George; Mu, Xingjiang; Li, Yutian; Kranias, Evangelia G.; Wang, Yigang; Fan, Guo-Chang Share Save
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