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Discovery and Optimization of Pyrazine Carboxamide AZ3246, a Selective HPK1 Inhibitor Shields, Jason D.; Baker, David; Balazs, Amber Y. S.; Bommakanti, Gayathri; Casella, Robert; Cao, Shenggen; Cook, Steve; Escobar, Randolph A.; Fawell, Stephen; Gibbons, Francis D.; Giblin, Kathryn A.; Goldberg, Frederick W.; Gosselin, Eric; Grebe, Tyler; Hariparsad, Niresh; Hatoum-Mokdad, Holia; Howells, Rachel; Hughes, Samantha J.; Jackson, Anne; Reddy, Iswarya Karapa; Kettle, Jason G.; Lamont, Gillian M.; Lamont, Scott; Li, Min; Lill, Sten O. Nilsson; Mele, Deanna A.; Metrano, Anthony J.; Mfuh, Adelphe M.; Morrill, Lucas A.; Peng, Bo; Pflug, Alexander; Proia, Theresa A.; Rezaei, Hadi; Richards, Ryan; Richter, Magdalena; Robbins, Kevin J.; San Martin, Maryann; Schimpl, Marianne; Schuller, Alwin G.; Sha, Li; Shen, Minhui; Sheppeck, James E.; Singh, Meha; Stokes, Stephen; Song, Kun; Sun, Yuanyuan; Tang, Haoran; Wagner, David J.; Wang, Jianyan; Wang, Yanjun; Wilson, David M.; Wu, Allan; Wu, Chengyan; Wu, Dedong; Wu, Ye; Xu, Kevin; Yang, Yue; Yao, Tieguang; Ye, Minwei; Zhang, Andrew X.; Zhang, Hui; Zhai, Xiang; Zhou, Yanxiao; Ziegler, Robert E.; Grimster, Neil P. Share Save
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PET Imaging Using 89Zr-Labeled StarPEG Nanocarriers Reveals Heterogeneous Enhanced Permeability and Retention in Prostate Cancer Meher, Niranjan; Bidkar, Anil P.; Wadhwa, Anju; Bobba, Kondapa Naidu; Dhrona, Suchi; Dasari, Chandrashekhar; Mu, Changhua; Fong, Cyril O. Y.; Camara, Juan A.; Ali, Umama; Basak, Megha; Bulkley, David; Steri, Veronica; Fontaine, Shaun D.; Zhu, Jun; Oskowitz, Adam; Aggarwal, Rahul R.; Sriram, Renuka; Chou, Jonathan; Wilson, David M.; Seo, Youngho; Santi, Daniel V.; Ashley, Gary W.; Vanbrocklin, Henry F.; Flavell, Robert R. Share Save
Discovery and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity Smith, James M.; Barlaam, Bernard; Beattie, David; Bradshaw, Lauren; Chan, Ho Man; Chiarparin, Elisabetta; Collingwood, Olga; Cooke, Sophie L.; Cronin, Anna; Cumming, Iain; Dean, Emma; Debreczeni, Judit E.; del Barco Barrantes, Ivan; Diene, Coura; Gianni, Davide; Guerot, Carine; Guo, Xiaoxiao; Guven, Sinem; Hayhow, Thomas G.; Hong, Ted; Kemmitt, Paul D.; Lamont, Gillian M.; Lamont, Scott; Lynch, James T.; McWilliams, Lisa; Moore, Shaun; Raubo, Piotr; Robb, Graeme R.; Robinson, James; Scott, James S.; Srinivasan, Bharath; Steward, Oliver; Stubbs, Christopher J.; Syson, Karl; Tan, Lixiang; Turner, Oliver; Underwood, Elizabeth; Urosevic, Jelena; Vazquez-Chantada, Mercedes; Whittaker, Amy L.; Wilson, David M.; Winter-Holt, Jon J. Share Save
Structural and Physicochemical Features of Oral PROTACs Schade, Markus; Scott, James S.; Hayhow, Thomas G.; Pike, Andy; Terstiege, Ina; Ahlqvist, Marie; Johansson, Johan R.; Diene, Coura R.; Fallan, Charlene; Balazs, Amber Y. S.; Chiarparin, Elisabetta; Wilson, David Share Save
Phase II results of the porcupine (PORCN) inhibitor zamaporvint (RXC004) in genetically selected microsatellite stable colorectal cancer patients Cook, N.; Bridgewater, J. A.; Saunders, M. P.; Kopetz, S.; Garcia-Carbonero, R.; Beom, S-H.; O'Neil, B. H.; Wilson, R. H.; Graham, J.; Maurel, J.; Kim, T. W.; Chau, I.; Saleha, S.; Goodwin, L.; Wilson, D.; Robertson, J.; Timmis, H.; Asken, E.; Woodcock, S. A.; Morris, V. Share Save
Phase II results of the porcupine (PORCN) inhibitor zamaporvint (RXC004) in patients with pancreatic and biliary tract cancer Bridgewater, J. A.; Chantrill, L.; Gillmore, R.; Hubner, R.; Starling, N.; Froeling, F.; Wasan, H. S.; Basu, B.; Collison, F.; Markman, B.; Chisamore, M.; Goodwin, L.; Wilson, D.; Phillips, C.; Robertson, J.; Timmis, H.; Setchellova, Z.; Woodcock, S. A.; Valle, J. W. Share Save
Imaging the Granzyme Mediated Host Immune Response to Viral and Bacterial Pathogens In Vivo Using Positron Emission Tomography Pandey, Apurva; Chopra, Shalini; Cleary, Simon J.; Lopez-Alvarez, Marina; Quimby, Fiona M.; Alanizi, Aryn A. A.; Sakhamuri, Sasank; Zhang, Ningjing; Looney, Mark R.; Craik, Charles S.; Wilson, David M.; Evans, Michael J. Share Save
Prostate-Specific Membrane Antigen Targeted StarPEG Nanocarrier for Imaging and Therapy of Prostate Cancer Meher, Niranjan; Ashley, Gary W.; Bobba, Kondapa Naidu; Wadhwa, Anju; Bidkar, Anil P.; Dasari, Chandrashekhar; Mu, Changhua; Sankaranarayanan, Ramya Ambur; Serrano, Juan A. Camara; Raveendran, Athira; Bulkley, David P.; Aggarwal, Rahul; Greenland, Nancy Y.; Oskowitz, Adam; Wilson, David M.; Seo, Youngho; Santi, Daniel V.; Vanbrocklin, Henry F.; Flavell, Robert R. Share Save
Final results of the first-in-human study of the porcupine (PORCN) inhibitor zamaporvint (RXC004) in patients with advanced solid tumors Cook, Natalie; Blagden, Sarah; Lopez, Juanita; Sarker, Debashis; Greystoke, Alastair; Haris, Noor Md; Kazmi, Farasat; Anam, Kaiser; Franco, Ana Ortego; Pihlak, Rille; Goodwin, Louise; Wilson, David; Phillips, Caroline; Robertson, Jane; Timmis, Helen; Tilston, Craig; Woodcock, Simon A.; Plummer, Ruth Share Save
Bioorthogonal Radiolabeling of Azide-Modified Bacteria Using [18F]FB-sulfo-DBCO Alanizi, Aryn A.; Sorlin, Alexandre M.; Parker, Matthew F. L.; Lopez-Alvarez, Marina; Qin, Hecong; Lee, Sang Hee; Blecha, Joseph; Rosenberg, Oren S.; Engel, Joanne; Ohliger, Michael A.; Flavell, Robert R.; Wilson, David M. Share Save
Peptidoglycan-Targeted [18F]3,3,3-Trifluoro-d-alanine Tracer for Imaging Bacterial Infection Sorlin, Alexandre M.; Lopez-Alvarez, Marina; Biboy, Jacob; Gray, Joe; Rabbitt, Sarah J.; Rahim, Junaid Ur; Lee, Sang Hee; Bobba, Kondapa Naidu; Blecha, Joseph; Parker, Mathew F. L.; Flavell, Robert R.; Engel, Joanne; Ohliger, Michael; Vollmer, Waldemar; Wilson, David M. Share Save
Development of CD46 targeted alpha theranostics in prostate cancer using 134Ce/225Ac-Macropa-PEG4-YS5 Bobba, Kondapa Naidu; Bidkar, Anil P.; Wadhwa, Anju; Meher, Niranjan; Drona, Suchi; Sorlin, Alexandre M.; Bidlingmaier, Scott; Zhang, Li; Wilson, David M.; Chan, Emily; Greenland, Nancy Y.; Aggarwal, Rahul; VanBrocklin, Henry F.; He, Jiang; Chou, Jonathan; Seo, Youngho; Liu, Bin; Flavell, Robert R. Share Save
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Evaluating the Performance of Pathogen-Targeted Positron Emission Tomography Radiotracers in a Rat Model of Vertebral Discitis-Osteomyelitis Parker, Matthew F. L.; Lopez-Alvarez, Marina; Alanizi, Aryn A.; Luu, Justin M.; Polvoy, Ilona; Sorlin, Alexandre M.; Qin, Hecong; Lee, Sanghee; Rabbitt, Sarah J.; Pichardo-Gonzalez, Priamo A.; Ordonez, Alvaro A.; Blecha, Joseph; Rosenberg, Oren S.; Flavell, Robert R.; Engel, Joanne; Jain, Sanjay K.; Ohliger, Michael A.; Wilson, David M. Share Save
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The Development and Validation of Radiopharmaceuticals Targeting Bacterial Infection Signore, Alberto; Ordonez, Alvaro A.; Arjun, Chanda; Aulakh, Gurpreet Kaur; Beziere, Nicolas; Dadachova, Ekaterina; Ebenhan, Thomas; Granados, Ulises; Korde, Aruna; Jalilian, Amirreza; Lestari, Wening; Mukherjee, Archana; Petrik, Milos; Sakr, Tamer; Cuevas, Clara L. Santos; Welling, Mick M.; Zeevaart, Jan Rijn; Jain, Sanjay K.; Wilson, David M. Share Save
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