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SaveNRF2 Deficiency Attenuates Diabetic Kidney Disease in Db/Db Mice via Down-Regulation of Angiotensinogen, SGLT2, CD36, and FABP4 Expression and Lipid Accumulation in Renal Proximal Tubular Cells
Su, Ke; Zhao, Shui-Ling; Yang, Wen-Xia; Lo, Chao-Sheng; Chenier, Isabelle; Liao, Min-Chun; Pang, Yu-Chao; Peng, Jun-Zheng; Miyata, Kana N.; Cailhier, Jean-Francois; Ethier, Jean; Lattouf, Jean-Baptiste; Filep, Janos G.; Ingelfinger, Julie R.; Zhang, Shao-Ling; Chan, John S. D. Share Save Share Save Single-dose replicating poxvirus vector-based RBD vaccine drives robust humoral and T cell immune response against SARS-CoV-2 infectionBoulton, Stephen; Poutou, Joanna; Martin, Nikolas T.; Azad, Taha; Singaravelu, Ragunath; Crupi, Mathieu J. F.; Jamieson, Taylor; He, Xiaohong; Marius, Ricardo; Petryk, Julia; de Souza, Christiano Tanese; Austin, Bradley; Taha, Zaid; Whelan, Jack; Khan, Sarwat T.; Pelin, Adrian; Rezaei, Reza; Surendran, Abera; Tucker, Sarah; Fekete, Emily E. F.; Dave, Jaahnavi; Diallo, Jean-Simon; Auer, Rebecca; Angel, Jonathan B.; Cameron, D. William; Cailhier, Jean-Francois; Lapointe, Rejean; Potts, Kyle; Mahoney, Douglas J.; Bell, John C.; Ilkow, Carolina S. Share Save Exploring cannabidiol effects on inflammatory markers in individuals with cocaine use disorder: a randomized controlled trialMorissette, Florence; Mongeau-Perusse, Violaine; Rizkallah, Elie; Thebault, Pamela; Lepage, Stephanie; Brissette, Suzanne; Bruneau, Julie; Dubreucq, Simon; Stip, Emmanuel; Cailhier, Jean-Francois; Jutras-Aswad, Didier Share Save Identification of SARS-CoV-2-specific immune alterations in acutely ill patientsRebillard, Rose-Marie; Charabati, Marc; Grasmuck, Camille; Filali-Mouhim, Abdelali; Tastet, Olivier; Brassard, Nathalie; Daigneault, Audrey; Bourbonniere, Lyne; Anand, Sai Priya; Balthazard, Renaud; Beaudoin-Bussieres, Guillaume; Gasser, Romain; Benlarbi, Mehdi; Moratalla, Ana Carmena; Solorio, Yves Carpentier; Boutin, Marianne; Farzam-kia, Negar; Descoteaux-Dinelle, Jade; Fournier, Antoine Philippe; Gowing, Elizabeth; Laumaea, Annemarie; Jamann, Helene; Lahav, Boaz; Goyette, Guillaume; Lemaitre, Florent; Mamane, Victoria Hannah; Prevost, Jeremie; Richard, Jonathan; Thai, Karine; Cailhier, Jean-Francois; Chomont, Nicolas; Finzi, Andres; Chasse, Michael; Durand, Madeleine; Arbour, Nathalie; Kaufmann, Daniel E.; Prat, Alexandre; Larochelle, Catherine Share Save Overexpression of Nrf2 in Renal Proximal Tubular Cells Stimulates Sodium-Glucose Cotransporter 2 Expression and Exacerbates Dysglycemia and Kidney Injury in Diabetic MiceZhao, Shuiling; Lo, Chao-Sheng; Miyata, Kana N.; Ghosh, Anindya; Zhao, Xin-Ping; Chenier, Isabelle; Cailhier, Jean-Francois; Ethier, Jean; Lattouf, Jean-Baptiste; Filep, Janos G.; Ingelfinger, Julie R.; Zhang, Shao-Ling; Chan, John S. D. Share Save HSP90 Inhibitor Improves Lung Protection in Porcine Model of Donation After Circulatory ArrestNasir, Basil S.; Landry, Caroline; Menaouar, Ahmed; Germain, Jean-Francois; Sarkissian, Shant Der; Stevens, Louis-Mathieu; Aceros, Henry; Cailhier, Jean-Francois; Leduc, Charles; Liberman, Moishe; Noiseux, Nicolas; Ferraro, Pasquale Share Save A Randomized Controlled Study to Evaluate the Safety and Reactogenicity of a Novel rVLP-Based Plant Virus Nanoparticle Adjuvant Combined with Seasonal Trivalent Influenza Vaccine Following Single Immunization in Healthy Adults 18-50 Years of AgeLangley, Joanne; Pastural, Elodie; Halperin, Scott; McNeil, Shelly; ElSherif, May; MacKinnon-Cameron, Donna; Ye, Lingyun; Grange, Cecile; Thibodeau, Valerie; Cailhier, Jean-Francois; Lapointe, Rejean; McElhaney, Janet; Martin, Luis; Bolduc, Marilene; Laliberte-Gagne, Marie-Eve; Leclerc, Denis; Savard, Pierre Share Save Increased urinary excretion of hedgehog interacting protein (uHhip) in early diabetic kidney diseaseMiyata, Kana N.; Zhao, Xin-Ping; Chang, Shiao-Ying; Liao, Min-Chun; Lo, Chao-Sheng; Chenier, Isabelle; Ethier, Jean; Cailhier, Jean-Francois; Lattouf, Jean-Baptiste; Troyanov, Stephan; Chiasson, Jean-Louis; Ingelfinger, Julie R.; Chan, John S. D.; Zhang, Shao-Ling Share Save Targeting the mTOR pathway uncouples the efficacy and toxicity of PD-1 blockade in renal transplantationEsfahani, Khashayar; Al-Aubodah, Tho-Alfakar; Thebault, Pamela; Lapointe, Rejean; Hudson, Marie; Johnson, Nathalie A.; Baran, Dana; Bhulaiga, Najwa; Takano, Tomoko; Cailhier, Jean-Francois; Piccirillo, Ciriaco A.; Miller, Wilson H. Share Save Failed immune responses across multiple pathologies share pan-tumor and circulating lymphocytic targetsMonette, Anne; Morou, Antigoni; Al-Banna, Nadia A.; Rousseau, Louise; Lattouf, Jean-Baptiste; Rahmati, Sara; Tokar, Tomas; Routy, Jean-Pierre; Cailhier, Jean-Francois; Kaufmann, Daniel E.; Jurisica, Igor; Lapointe, Rejean Share Save Selection and Receipt of Kidney Replacement in Critically Ill Older Patients with AKIBagshaw, Sean M.; Adhikari, Neill K. J.; Burns, Karen E. A.; Friedrich, Jan O.; Bouchard, Josee; Lamontagne, Francois; McIntrye, Lauralyn A.; Cailhier, Jean-Francois; Dodek, Peter; Stelfox, Henry T.; Herridge, Margaret; Lapinsky, Stephen; Muscedere, John; Barton, James; Griesdale, Donald; Soth, Mark; Ambosta, Althea; Lebovic, Gerald; Wald, Ron; Gibney, R. T. Noel; Baig, Nadia; Marinoff, Nicole; Perez, Adic; Burns, Karen; Friedrich, Jan; Lee, Julia; Lee, Yoon; Salway, Kurtis; Sandhu, Gyan; Smith, Oda; Wang, Melissa; Duca, Anatolie; Berube, Patrick; Fournier, Helene; McIntrye, Lauralyn; Watpool, Irene; Porteus, Rebecca; Gomes, Brigette; Benettaib, Fatna; Ashley, Betty Jean; Alcuaz, Victoria; Ruddell, Stacey; Matte, Andrea; Shah, Sumesh; Hunt, Miranda; Georgescu, Ilinca; Polewicz, Dorota; Foster, Denise; Wachmann, Kristine Share Save Share Save Share Save Heterogeneous Nuclear Ribonucleoprotein F Stimulates Sirtuin-1 Gene Expression and Attenuates Nephropathy Progression in Diabetic MiceLo, Chao-Sheng; Shi, Yixuan; Chenier, Isabelle; Ghosh, Anindya; Wu, Chin-Han; Cailhier, Jean-Francois; Ethier, Jean; Lattouf, Jean-Baptiste; Filep, Janos G.; Ingelfinger, Julie R.; Zhang, Shao-Ling; Chan, John S. D. Share Save MARCH1 E3 Ubiquitin Ligase Dampens the Innate Inflammatory Response by Modulating Monocyte Functions in MiceGalbas, Tristan; Raymond, Maxime; Sabourin, Antoine; Bourgeois-Daigneault, Marie-Claude; Guimont-Desrochers, Fanny; Yun, Tae Jin; Cailhier, Jean-Francois; Ishido, Satoshi; Lesage, Sylvie; Cheong, Cheolho; Thibodeau, Jacques Share Save Lymphocytic Microparticles Modulate Angiogenic Properties of Macrophages in Laser-induced Choroidal NeovascularizationTahiri, Houda; Omri, Samy; Yang, Chun; Duhamel, Francois; Samarani, Suzanne; Ahmad, Ali; Vezina, Mark; Bussieres, Martin; Vaucher, Elvire; Sapieha, Przemyslaw; Hickson, Gilles; Hammamji, Karim; Lapointe, Rejean; Rodier, Francis; Tremblay, Sophie; Royal, Isabelle; Cailhier, Jean-Francois; Chemtob, Sylvain; Hardy, Pierre Share Save Share Save The 20S proteasome core, active within apoptotic exosome-like vesicles, induces autoantibody production and accelerates rejectionDieude, Melanie; Bell, Christina; Turgeon, Julie; Beillevaire, Deborah; Pomerleau, Luc; Yang, Bing; Hamelin, Katia; Qi, Shijie; Pallet, Nicolas; Beland, Chanel; Dhahri, Wahiba; Cailhier, Jean-Francois; Rousseau, Matthieu; Duchez, Anne-Claire; Levesque, Tania; Lau, Arthur; Rondeau, Christiane; Gingras, Diane; Muruve, Danie; Rivard, Alain; Cardinal, Heloise; Perreault, Claude; Desjardins, Michel; Boilard, Eric; Thibault, Pierre; Hebert, Marie-Josee Share Save 
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