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SRC inhibition enables formation of a growth suppressive MAGI1-PP2A complex in isocitrate dehydrogenase-mutant cholangiocarcinoma Luk, Iris S.; Bridgwater, Caroline M.; Yu, Angela; Boila, Liberalis D.; Yanez-Bartolome, Mariana; Lampano, Aaron E.; Hulahan, Taylor S.; Boukhali, Myriam; Kathiresan, Meena; Macarulla, Teresa; Kenerson, Heidi L.; Yamamoto, Naomi; Sokolov, David; Engstrom, Ian A.; Sullivan, Lucas B.; Lampe, Paul D.; Cooper, Jonathan A.; Yeung, Raymond S.; Tian, Tian V.; Haas, Wilhelm; Saha, Supriya K.; Kugel, Sita Share Save
A non-canonical MiT/TFE-dependent NRF2 program is a druggable vulnerability in multiple cancer types Luo, Xinbo; Lutterbach, Bart; Pancholi, Priya; Choi, Yeon Sook; Liu, Xiao; Munson, Phillip; Faisal, Saqib; Whipple, David A.; Smith, Robert A.; Weiner, Warren S.; Johnson, David K.; Boukhali, Myriam; Persky, Nicole S.; Rees, Matthew G.; Kitajima, Shunsuke; Barbie, David; Roy, Anuradha; Baltezor, Michael; Rajewski, Lian; McGuinness, William; Haslam, John; Sadagopan, Ananthan; Yoon, Charles H.; Johannessen, Cory M.; Lian, Christine G.; Hornick, Jason L.; Viswanathan, Srinivas R.; Liu, David; Nienaber, Vicki; Haas, Wilhelm; Schoenen, Frank J.; Fisher, David E.; Haq, Rizwan Share Save
Ribosome changes reprogram translation for chemosurvival in G0 leukemic cells Datta, Chandreyee; Truesdell, Samuel S.; Wu, Keith Q.; Bukhari, Syed I. A.; Ngue, Harrison; Buchanan, Brienna; Le Tonqueze, Olivier; Lee, Sooncheol; Kollu, Swapna; Granovetter, Madeleine A.; Boukhali, Myriam; Kreuzer, Johannes; Batool, Maheen S.; Balaj, Leonora; Haas, Wilhelm; Vasudevan, Shobha Share Save
Integrated multi-omics analysis of RB-loss identifies widespread cellular programming and synthetic weaknesses (vol 4, 977, 2021) Rajasekaran, Swetha; Siddiqui, Jalal; Rakijas, Jessica; Nicolay, Brandon; Lin, Chenyu; Khan, Eshan; Patel, Rahi; Morris, Robert; Wyler, Emanuel; Boukhali, Myriam; Balasubramanyam, Jayashree; Ranjith Kumar, R.; Van Rechem, Capucine; Vogel, Christine; Elchuri, Sailaja V.; Landthaler, Markus; Obermayer, Benedikt; Haas, Wilhelm; Dyson, Nicholas; Miles, Wayne Share Save
Integrated multi-omics analysis of RB-loss identifies widespread cellular programming and synthetic weaknesses Rajasekaran, Swetha; Siddiqui, Jalal; Rakijas, Jessica; Nicolay, Brandon; Lin, Chenyu; Khan, Eshan; Patel, Rahi; Morris, Robert; Wyler, Emanuel; Boukhali, Myriam; Balasubramanyam, Jayashree; Ranjith Kumar, R.; Van Rechem, Capucine; Vogel, Christine; Elchuri, Sailaja V.; Landthaler, Markus; Obermayer, Benedikt; Haas, Wilhelm; Dyson, Nicholas; Miles, Wayne Share Save
E2F/Dp inactivation in fat body cells triggers systemic metabolic changes Zappia, Maria Paula; Guarner, Ana; Kellie-Smith, Nadia; Rogers, Alice; Morris, Robert; Nicolay, Brandon; Boukhali, Myriam; Haas, Wilhelm; Dyson, Nicholas J.; Frolov, Maxim, V Share Save
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Tau Contributes to Sevoflurane-induced Neurocognitive Impairment in Neonatal Mice Yu, Yang; Yang, Yongyan; Tan, Hong; Boukhali, Myriam; Khatri, Ashok; Yu, Yonghao; Hua, Fuzhou; Liu, Ling; Li, Mengzhu; Yang, Guang; Dong, Yuanlin; Zhang, Yiying; Haas, Wilhelm; Xie, Zhongcong Share Save
Obtusaquinone: A Cysteine-Modifying Compound That Targets Keap1 for Degradation Badr, Christian E.; da Hora, Cintia Carla; Kirov, Aleksandar B.; Tabet, Elie; Amante, Romain; Maksoud, Semer; Nibbs, Antoinette E.; Fitzsimons, Evelyn; Boukhali, Myriam; Chen, John W.; Chiu, Norman H. L.; Nakano, Ichiro; Haas, Wilhelm; Mazitschek, Ralph; Tannous, Bakhos A. Share Save
A post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells Lee, Sooncheol; Micalizzi, Douglas; Truesdell, Samuel S.; Bukhari, Syed I. A.; Boukhali, Myriam; Lombardi-Story, Jennifer; Kato, Yasutaka; Choo, Min-Kyung; Dey-Guha, Ipsita; Ji, Fei; Nicholson, Benjamin T.; Myers, David T.; Lee, Dongjun; Mazzola, Maria A.; Raheja, Radhika; Langenbucher, Adam; Haradhvala, Nicholas J.; Lawrence, Michael S.; Gandhi, Roopali; Tiedje, Christopher; Diaz-Munoz, Manuel D.; Sweetser, David A.; Sadreyev, Ruslan; Sykes, David; Haas, Wilhelm; Haber, Daniel A.; Maheswaran, Shyamala; Vasudevan, Shobha Share Save
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SETD1A protects from senescence through regulation of the mitotic gene expression program Tajima, Ken; Matsuda, Satoru; Yae, Toshifumi; Drapkin, Benjamin J.; Morris, Robert; Boukhali, Myriam; Niederhoffer, Kira; Comaills, Valentine; Dubash, Taronish; Nieman, Linda; Guo, Hongshan; Magnus, Neelima K. C.; Dyson, Nick; Shioda, Toshihiro; Haas, Wilhelm; Haber, Daniel A.; Maheswaran, Shyamala Share Save
A Code of Mono-phosphorylation Modulates the Function of RB Sanidas, Ioannis; Morris, Robert; Fella, Katerina A.; Rumde, Purva H.; Boukhali, Myriam; Tai, Eric C.; Ting, David T.; Lawrence, Michael S.; Haas, Wilhelm; Dyson, Nicholas J. Share Save
Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism Patra, Krushna C.; Kato, Yasutaka; Mizukami, Yusuke; Widholz, Sebastian; Boukhali, Myriam; Revenco, Iulia; Grossman, Elizabeth A.; Ji, Fei; Sadreyev, Ruslan I.; Liss, Andrew S.; Screaton, Robert A.; Sakamoto, Kei; Ryan, David P.; Mino-Kenudson, Mari; Castillo, Carlos Fernandez-Del; Nomura, Daniel K.; Haas, Wilhelm; Bardeesy, Nabeel Share Save
Integrated in vivo multiomics analysis identifies p21-activated kinase signaling as a driver of colitis Lyons, Jesse; Brubaker, Douglas K.; Ghazi, Phaedra C.; Baldwin, Katherine R.; Edwards, Amanda; Boukhali, Myriam; Strasser, Samantha Dale; Suarez-Lopez, Lucia; Lin, Yi-Jang; Yajnik, Vijay; Kissil, Joseph L.; Haas, Wilhelm; Lauffenburger, Douglas A.; Haigis, Kevin M. Share Save
Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation Olson, Calla M.; Jiang, Baishan; Erb, Michael A.; Liang, Yanke; Doctor, Zainab M.; Zhang, Zinan; Zhang, Tinghu; Kwiatkowski, Nicholas; Boukhali, Myriam; Green, Jennifer L.; Haas, Wilhelm; Nomanbhoy, Tyzoon; Fischer, Eric S.; Young, Richard A.; Bradner, James E.; Winter, Georg E.; Gray, Nathanael S. Share Save
E2F/DP Prevents Cell-Cycle Progression in Endocycling Fat Body Cells by Suppressing dATM Expression Guarner, Ana; Morris, Robert; Korenjak, Michael; Boukhali, Myriam; Zappia, Maria Paula; Van Rechem, Capucine; Whetstine, Johnathan R.; Ramaswamy, Sridhar; Zou, Lee; Frolov, Maxim V.; Haas, Wilhelm; Dyson, Nicholas J. Share Save
TOX Regulates Growth, DNA Repair, and Genomic Instability in T-cell Acute Lymphoblastic Leukemia Lobbardi, Riadh; Pinder, Jordan; Martinez-Pastor, Barbara; Theodorou, Marina; Blackburn, Jessica S.; Abraham, Brian J.; Namiki, Yuka; Mansour, Marc; Abdelfattah, Nouran S.; Molodtsov, Aleksey; Alexe, Gabriela; Toiber, Debra; de Waard, Manon; Jain, Esha; Boukhali, Myriam; Lion, Mattia; Bhere, Deepak; Shah, Khalid; Gutierrez, Alejandro; Stegmaier, Kimberly; Silverman, Lewis B.; Sadreyev, Ruslan I.; Asara, John M.; Oettinger, Marjorie A.; Haas, Wilhelm; Look, A. Thomas; Young, Richard A.; Mostoslavsky, Raul; Dellaire, Graham; Langenau, David M. Share Save
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