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J

Jen Q. Pan

Broad Institute of MIT and Harvard

27H-index
109Paper Count
3.1KCitation Count
Published Papers 40
Publication Date
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Parvalbumin interneuron activation rescues both seizures and impaired social novelty in digenic absence epilepsy mice
errScience Advances
IF12.5
err2026-07-31
err0
errOAAI
errQing-Long Miao; James Okoh; Ahmet S. Asan; Saifina Karedia; Jen Q. Pan; Mauro Costa-Mattioli; Jeffrey L. Noebels
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errSave
Srrm2 haploinsufficiency drives SynGAP-γ reduction, Agap3 mis-splicing, and oligodendrocyte deficits in a genetic mouse model of schizophrenia
errCell Reports
IF6.9
err2026-05-25
err0
errOAAI
errSameer Aryal; Chuhan Geng; Margaret A. Yin; Min Jee Kwon; Zohreh Farsi; Nathaniel Goble; Ahmet S. Asan; Kira S. Brenner; Nate Shepard; Ana Geller; Katherine J. Stalnaker; Olivia Seidel; Yining Wang; Ally Nicolella; Bryan J. Song; Sean P. Moran; Hasmik Keshishian; Steven A. Carr; Jen Q. Pan; Morgan Sheng
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errSave
Loss of schizophrenia risk gene XPO7 disrupts neuronal excitability and network regularity via altered Na+ channel dynamics in human neurons
errMolecular Psychiatry
IF10.1
err2026-04-15
err0
errOAAI
errLei Cui; Erkin Kurganov; Derek Hawes; Philipp Hornauer; Raozhou Lin; Yining Wang; Andreas Hierlemann; Morgan Sheng; Ralda Nehme; Jen Q. Pan
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errSave
Characterization of the functional and clinical impacts of CACNA1A missense variants found in neurodevelopmental disorders
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2025-12-10
err0
PREAI
errKurganov, Erkin; Cui, Lei; Budnik, Nikita; Chen, Siwei; Olivares, Erick; Baez-Nieto, David; Asan, Ahmet S.; Lusk, Laina; Smith, Lacey; Jo, Sooyeon; Marques, Diogo; Nehme, Ralda; Mullegama, Sureni V.; Lindy, Amanda; George, Alfred L.; Poduri, Annapurna; Helbig, Ingo; Daly, Mark; Pan, Jen Q.
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errSave
Publisher Correction: CRISPR activation for SCN2A-related neurodevelopmental disorders
errNature
IF48.5
err2025-12-08
err0
errOAAI
errSerena Tamura; Andrew D. Nelson; Perry W. E. Spratt; Elizabeth C. Hamada; Xujia Zhou; Henry Kyoung; Zizheng Li; Coline Arnould; Vladyslav Barskyi; Beniamin Krupkin; Kiana Young; Jingjing Zhao; Stephanie S. Holden; Atehsa Sahagun; Caroline M. Keeshen; Congyi Lu; Roy Ben-Shalom; Sunrae E. Taloma; Selin Schamiloglu; Ying C. Li; Lia Min; Paul M. Jenkins; Jen Q. Pan; Jeanne T. Paz; Stephan J. Sanders; Navneet Matharu; Nadav Ahituv; Kevin J. Bender
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errSave
CRISPR activation for SCN2A-related neurodevelopmental disorders
errNature
IF48.5
err2025-09-17
err0
PREAI
errSerena Tamura; Andrew D. Nelson; Perry W. E. Spratt; Elizabeth C. Hamada; Xujia Zhou; Henry Kyoung; Zizheng Li; Coline Arnould; Vladyslav Barskyi; Beniamin Krupkin; Kiana Young; Jingjing Zhao; Stephanie S. Holden; Atehsa Sahagun; Caroline M. Keeshen; Congyi Lu; Roy Ben-Shalom; Sunrae E. Taloma; Selin Schamiloglu; Ying C. Li; Lia Min; Paul M. Jenkins; Jen Q. Pan; Jeanne T. Paz; Stephan J. Sanders; Navneet Matharu; Nadav Ahituv; Kevin J. Bender
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errSave
NREM Sleep Signatures of Bipolar Disorder
errSLEEP
IF4.9
err2025-05-19
err0
PREAI
errGong, Naihua; Kozhemiako, Nataliia; Purcell, Shaun; Pan, Jen
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errSave
Unveiling distinct representations of P3a in schizophrenia through two-stimulus and three-stimulus auditory oddball paradigms
errSCHIZOPHRENIA RESEARCH
IF3.5
err2025-03-01
err0
PREAI
errJiang, Chenguang; Wang, Jun; Sun, Yifan; Tan, Shuping; Percell, Shaun M.; Zhou, Zhenhe; Pan, Jen Q.; Hall, Mei-Hua; GRINS consortium, Mei-Hua
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errSave
A spectrum of altered non-rapid eye movement sleep in schizophrenia
errSLEEP
IF4.9
err2024-09-19
err1
errOAAI
errKozhemiako, Nataliia; Jiang, Chenguang; Sun, Yifan; Guo, Zhenglin; Chapman, Sinead; Gai, Guanchen; Wang, Zhe; Zhou, Lin; Li, Shen; Law, Robert G.; Wang, Lei A.; Mylonas, Dimitrios; Shen, Lu; Murphy, Michael; Qin, Shengying; Zhu, Wei; Zhou, Zhenhe; Stickgold, Robert; Huang, Hailiang; Tan, Shuping; Manoach, Dara S.; Wang, Jun; Hall, Mei-Hua; Pan, Jen Q.; Purcell, Shaun M.
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errSave
Scanning mutagenesis of the voltage-gated sodium channel Na V 1.2 using base editing (Vol 42, 112563, 2023)
errCELL REPORTS
IF6.9
err2024-06-01
err1
errOAAI
errPablo, Juan Lorenzo B.; Cornett, Savannah L.; Wang, Lei A.; Jo, Sooyeon; Brunger, Tobias; Budnik, Nikita; Hegde, Mudra; Dekeyser, Jean -Marc; Thompson, Christopher H.; Doench, John G.; Lal, Dennis; George Jr, Alfred L.; Pan, Jen Q.
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Differential functional consequences of GRIN2A mutations associated with schizophrenia and neurodevelopmental disorders
errSCIENTIFIC REPORTS
IF3.9
err2024-02-02
err3
errOAAI
errShepard, Nate; Baez-Nieto, David; Iqbal, Sumaiya; Kurganov, Erkin; Budnik, Nikita; Campbell, Arthur J.; Pan, Jen Q.; Sheng, Morgan; Farsi, Zohreh
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Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice
errNEURON
IF15
err2023-11-01
err14
errOAAI
errFarsi, Zohreh; Nicolella, Ally; Simmons, Sean K.; Aryal, Sameer; Shepard, Nate; Brenner, Kira; Lin, Sherry; Herzog, Linnea; Moran, Sean P.; Stalnaker, Katherine J.; Shin, Wangyong; Gazestani, Vahid; Song, Bryan J.; Bonanno, Kevin; Keshishian, Hasmik; Carr, Steven A.; Pan, Jen Q.; Macosko, Evan Z.; Datta, Sandeep Robert; Dejanovic, Borislav; Kim, Eunjoon; Levin, Joshua Z.; Sheng, Morgan
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Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction
errAMERICAN JOURNAL OF HUMAN GENETICS
IF8.1
err2023-10-01
err12
errOAAI
errShi, Xi; Lu, Congyi; Corman, Alba; Nikish, Alexandra; Zhou, Yang; Platt, Randy J.; Iossifov, Ivan; Zhang, Feng; Pan, Jen Q.; Sanjana, Neville E.
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errSave
GENETIC CORRELATES OF SLEEP SPINDLE ABNORMALITIES IN SCHIZOPHRENIA
errEUROPEAN NEUROPSYCHOPHARMACOLOGY
IF6.7
err2023-10-01
err0
PREAI
errWang, Jun; Kozhemiako, Nataliia; Jiang, Chenguang; Guo, Zhenglin; Chapman, Sinead; Li, Shen; Shen, Lu; Qin, Shengying; Murphy, Michael; Manoach, Dara; Zhou, Zhenhe; Hall, Meihua; Pan, Jen Q.; Huang, Hailiang; Purcell, Shaun M.
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errSave
Scanning mutagenesis of the voltage-gated sodium channel NaV1.2 using base editing
errCELL REPORTS
IF6.9
err2023-06-01
err2
errOAAI
errPablo, Juan Lorenzo B.; Cornett, Savannah L.; Wang, Lei A.; Jo, Sooyeon; Bruenger, Tobias; Budnik, Nikita; Hegde, Mudra; DeKeyser, Jean-Marc; Thompson, Christopher H.; Doench, John G.; Lal, Dennis; George Jr, Alfred L.; Pan, Jen Q.
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errSave
IntelliSleepScorer, a software package with a graphic user interface for automated sleep stage scoring in mice based on a light gradient boosting machine algorithm
errSCIENTIFIC REPORTS
IF3.9
err2023-03-15
err4
errOAAI
errWang, Lei A.; Kern, Ryan; Yu, Eunah; Choi, Soonwook; Pan, Jen Q.
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Mouse mutants in schizophrenia risk genes GRIN2A and AKAP11 show EEG abnormalities in common with schizophrenia patients
errTRANSLATIONAL PSYCHIATRY
IF6.2
err2023-03-13
err18
errOAAI
errHerzog, Linnea E.; Wang, Lei; Yu, Eunah; Choi, Soonwook; Farsi, Zohreh; Song, Bryan J.; Pan, Jen Q.; Sheng, Morgan
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errSave
Non-rapid eye movement sleep and wake neurophysiology in schizophrenia
errELIFE
IF0
err2022-05-17
err17
errOAAI
errKozhemiako, Nataliia; Wang, Jun; Jiang, Chenguang; Wang, Lei A.; Gai, Guanchen; Zou, Kai; Wang, Zhe; Yu, Xiaoman; Zhou, Lin; Li, Shen; Guo, Zhenglin; Law, Robert; Coleman, James; Mylonas, Dimitrios; Shen, Lu; Wang, Guoqiang; Tan, Shuping; Qin, Shengying; Huang, Hailiang; Murphy, Michael; Stickgold, Robert; Manoach, Dara; Zhou, Zhenhe; Zhu, Wei; Hal, Mei-Hua; Purcell, Shaun M.; Pan, Jen Q.; Peyrache, Adrien
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AKT inhibition in the central nervous system induces signaling defects resulting in psychiatric symptomatology
errCELL AND BIOSCIENCE
IF6.2
err2022-05-07
err14
errOAAI
errTsimberidou, Apostolia-Maria; Skliris, Antonis; Valentine, Alan; Shaw, Jamie; Hering, Ursula; Vo, Henry Hiep; Chan, Tung On; Armen, Roger S.; Cottrell, Jeffrey R.; Pan, Jen Q.; Tsichlis, Philip N.
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Analysing an allelic series of rare missense variants of CACNA1I in a Swedish schizophrenia cohort
errBRAIN
IF11.7
err2021-12-17
err21
errOAAI
errBaez-Nieto, David; Allen, Andrew; Akers-Campbell, Seth; Yang, Lingling; Budnik, Nikita; Pupo, Amaury; Shin, Young-Cheul; Genovese, Giulio; Liao, Maofu; Perez-Palma, Eduardo; Heyne, Henrike; Lal, Dennis; Lipscombe, Diane; Pan, Jen Q.
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Research Directions

No research directions
Co-authors
Cooperation Journals
M
Mark J. Daly
H-index: 224 · Papers: 1.2K
A
Aviv Regev
H-index: 208 · Papers: 965
S
Stuart L. Schreiber
H-index: 166 · Papers: 1.3K
S
Steven A. Carr
H-index: 152 · Papers: 987
M
Morgan Sheng
H-index: 141 · Papers: 365
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