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Phase I/II Study of AXL-Specific Antibody-Drug Conjugate Enapotamab Vedotin in Patients with Advanced Solid Tumors Rohrberg, Kristoffer Staal; Lopez, Juanita S.; Milhem, Mohammed M.; Blank, Christian U.; Reijers, Irene; Thistlethwaite, Fiona; Plummer, Ruth; Piha-Paul, Sarina A.; Janne, Pasi A.; Shum, Elaine; Shaw, Heather M.; Debruyne, Philip R.; Lao, Cristopher; Baurain, Jean-Francois; Choe, Jennifer H.; Gort, Eelke; Zhao, Yujie; Jerusalem, Guy; Schoffski, Patrick; Chen, Andrew William; Cohen, Eric A.; Mankowski, Walter C.; Roshkovan, Leonid; Katz, Sharyn I.; Kontos, Despina; Brady, Lauren K.; Qutaish, Mohammed; Castro, Patricia Garrido; Pencheva, Nora; Bajaj, Gaurav; Fu, Yali; Windfeld, Kristian; Reiter, Panagiota; Jure-Kunkel, Maria; Higgs, Brandon W.; Amiri, Katayoun I.; Ahmadi, Tahamtan; Forssmann, Ulf; Ramalingam, Suresh S.; Vergote, Ignace Share Save
A plain language summary of the CEPHEUS study of daratumumab plus bortezomib, lenalidomide, and dexamethasone for people with newly diagnosed multiple myeloma who are not expected to receive a stem cell transplant Usmani, Saad Z.; Facon, Thierry; Hungria, Vania; Bahlis, Nizar J.; Venner, Christopher P.; Braunstein, Marc; Pour, Ludek; Marti, Josep M.; Basu, Supratik; Cohen, Yael C.; Matsumoto, Morio; Suzuki, Kenshi; Hulin, Cyrille; Grosicki, Sebastian; Legiec, Wojciech; Beksac, Meral; Maiolino, Angelo; Takamatsu, Hiroyuki; Perrot, Aurore; Turgut, Mehmet; Ahmadi, Tahamtan; Liu, Weiping; Wang, Jianping; Chastain, Katherine; Vermeulen, Jessica; Krevvata, Maria; Lopez-Masi, Lorena; Carey, Jodi; Rowe, Melissa; Carson, Robin; Zweegman, Sonja Share Save
Acasunlimab, an Fc-inert PD-L1x4-1BB bispecific antibody, combined with PD-1 blockade potentiates antitumor immunity via complementary immune modulatory effects Capello, Michela; Sette, Angelica; Plantinga, Theo; Thalhauser, Craig J.; Spires, Vanessa M.; Nuermberger, Kristina B.; Blum, Jordan M.; Higgs, Brandon W.; Garrido Castro, Patricia; Yu, Christina; Costa Sa, Carol; Fellermeier-Kopf, Sina; Burm, Saskia M.; Strumane, Kristin; Toker, Aras; Imle, Andrea; de Andrade Pereira, Bruna; Muik, Alexander; Ahmadi, Tahamtan; Tuereci, Oezlem; Fereshteh, Mark; Sahin, Ugur; Jure-Kunkel, Maria; Pencheva, Nora Share Save
Optimal Dosing Regimen for Epcoritamab, a Subcutaneous Bispecific Antibody, in Relapsed or Refractory Large B-Cell Lymphoma Li, Tommy; Gibiansky, Leonid; Parikh, Apurvasena; Putnins, Matthew; Chiu, Christopher W.; Sacchi, Mariana; Feng, Huaibao; Ahmadi, Tahamtan; Gupta, Manish; Xu, Steven Share Save
A plain language summary of the PERSEUS study of daratumumab plus bortezomib, lenalidomide, and dexamethasone for treating newly diagnosed multiple myeloma Sonneveld, Pieter; Dimopoulos, Meletios A.; Boccadoro, Mario; Quach, Hang; Ho, P. Joy; Beksac, Meral; Hulin, Cyrille; Antonioli, Elisabetta; Leleu, Xavier; Mangiacavalli, Silvia; Perrot, Aurore; Cavo, Michele; Belotti, Angelo; Broijl, Annemiek; Gay, Francesca; Mina, Roberto; van de Donk, Niels W. C. J.; Katodritou, Eirini; Schjesvold, Fredrik; Balari, Anna Sureda; Rosinol, Laura; Delforge, Michel; Roeloffzen, Wilfried; Silzle, Tobias; Vangsted, Annette; Einsele, Hermann; Spencer, Andrew; Hajek, Roman; Jurczyszyn, Artur; Lonergan, Sarah; Ahmadi, Tahamtan; Liu, Yanfang; Wang, Jianping; Vieyra, Diego; van Brummelen, Emilie M. J.; Vanquickelberghe, Veronique; Sitthi-Amorn, Anna; de Boer, Carla J.; Carson, Robin; Rodriguez-Otero, Paula; Blade, Joan; Moreau, Philippe Share Save
Epcoritamab monotherapy in patients with relapsed or refractory follicular lymphoma (EPCORE NHL-1): a phase 2 cohort of a single-arm, multicentre study Linton, Kim M.; Vitolo, Umberto; Jurczak, Wojciech; Lugtenburg, Pieternella J.; Gyan, Emmanuel; Sureda, Anna; Christensen, Jacob Haaber; Hess, Brian; Tilly, Herve; Cordoba, Raul; Lewis, David John; Okada, Craig; Hutchings, Martin; Clausen, Michael Roost; Sancho, Juan-Manuel; Cochrane, Tara; Leppa, Sirpa; Chamuleau, Martine E. D.; Gernhardt, Diana; Altintas, Isil; Liu, Yan; Ahmadi, Tahamtan; Dinh, Minh H.; Hoehn, Daniela; Favaro, Elena; Elliott, Brian; Thieblemont, Catherine; Vose, Julie M. Share Save
Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone for Multiple Myeloma Sonneveld, Pieter; Dimopoulos, Meletios A.; Boccadoro, Mario; Quach, Hang; Ho, P. Joy; Beksac, Meral; Hulin, Cyrille; Antonioli, Elisabetta; Leleu, Xavier; Mangiacavalli, Silvia; Perrot, Aurore; Cavo, Michele; Belotti, Angelo; Broijl, Annemiek; Gay, Francesca; Mina, Roberto; Nijhof, Inger S.; van de Donk, Niels W. C. J.; Katodritou, Eirini; Schjesvold, Fredrik; Sureda Balari, Anna; Rosinol, Laura; Delforge, Michel; Roeloffzen, Wilfried; Silzle, Tobias; Vangsted, Annette; Einsele, Hermann; Spencer, Andrew; Hajek, Roman; Jurczyszyn, Artur; Lonergan, Sarah; Ahmadi, Tahamtan; Liu, Yanfang; Wang, Jianping; Vieyra, Diego; van Brummelen, Emilie M. J.; Vanquickelberghe, Veronique; Sitthi-Amorn, Anna; de Boer, Carla J.; Carson, Robin; Rodriguez-Otero, Paula; Blade, Joan; Moreau, Philippe Share Save
Daratumumab for patients with myeloma with early or late relapse after initial therapy: subgroup analysis of CASTOR and POLLUX Spencer, Andrew; Moreau, Philippe; Mateos, Maria-Victoria; Goldschmidt, Hartmut; Suzuki, Kenshi; Levin, Mark-David; Sonneveld, Pieter; Orlowski, Robert Z.; Yoon, Sung-Soo; Usmani, Saad Z.; Weisel, Katja; Reece, Donna; Ahmadi, Tahamtan; Pei, Huiling; Mayo, Wendy Garvin; Gai, Xue; Carey, Jodi; Bartlett, J. Blake; Carson, Robin; Dimopoulos, Meletios A. Share Save
DuoBody-EpCAMx4-1BB mediates conditional T cell co-stimulation and promotes antitumor activity in preclinical Fellermeier-Kopf, S.; Ioan-Facsinay, A.; Imle, A.; Diks, A. M.; Nuermberger, K. B.; Guelen, L.; Koehne, M.; Houtkamp, M.; Toker, A.; Burm, S. M.; Gamse, J.; Janaitis, C.; Satijn, D.; Muik, A.; Ahmadi, T.; Tuereci, O.; Kemper, K.; Sahin, U.; Breij, E. Share Save
Preclinical anti-tumour activity of HexaBody-CD38, a next-generation CD38 antibody with superior complement-dependent cytotoxic activity Hiemstra, Ida H.; Santegoets, Kim C. M.; Janmaat, Maarten L.; De Goeij, Bart E. C. G.; Ten Hagen, Wessel; van Dooremalen, Sanne; Boross, Peter; van den Brakel, Jeroen; Bosgra, Sieto; Andringa, Grietje; van Kessel-Welmers, Berris; Verzijl, Dennis; Hibbert, Richard G.; Frerichs, Kristine A.; Mutis, Tuna; van de Donk, Niels W. C. J.; Ahmadi, Tahamtan; Satijn, David; Sasser, A. Kate; Breij, Esther C. W. Share Save
GEN1042 (DuoBody-CD40x4-1BB)®in combination with PD-1 blockade reverses T-cell exhaustion in vivo Spires, Vanessa M.; Masters, Gregg; Yu, Christina; Hancock, Matt; Luijten, Monique N.; Muik, Alexander; Nuermberger, Kristina; Gieseke, Friederike; Ahmadi, Tahamtan; Tureci, Ozlem; Jure-Kunkel, Maria; Sahin, Ugur; Fereshteh, Mark; Adams, Homer C.; Blum, Jordan M. Share Save
Semimechanistic Physiologically-Based Pharmacokinetic/Pharmacodynamic Model Informing Epcoritamab Dose Selection for Patients With B-Cell Lymphomas Li, Tommy; Hiemstra, Ida H.; Chiu, Christopher; Oliveri, Roberto S.; Elliott, Brian; DeMarco, Dena; Salcedo, Theodora; Egerod, Frederikke Lihme; Sasser, Kate; Ahmadi, Tahamtan; Gupta, Manish Share Save
Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors Muik, Alexander; Garralda, Elena; Altintas, Isil; Gieseke, Friederike; Geva, Ravit; Ben-Ami, Eytan; Maurice-Dror, Corinne; Calvo, Emiliano; LoRusso, Patricia M.; Alonso, Guzman; Rodriguez-Ruiz, Maria E.; Schoedel, Kristina B.; Blum, Jordan M.; Sanger, Bianca; Salcedo, Theodora W.; Burm, Saskia M.; Stanganello, Eliana; Verzijl, Dennis; Vascotto, Fulvia; Sette, Angelica; Quinkhardt, Juliane; Plantinga, Theo S.; Toker, Aras; van den Brink, Edward N.; Fereshteh, Mark; Diken, Mustafa; Satijn, David; Kreiter, Sebastian; Breij, Esther C. W.; Bajaj, Gaurav; Lagkadinou, Eleni; Sasser, Kate; Tureci, Ozlem; Forssmann, Ulf; Ahmadi, Tahamtan; Sahin, Ugur; Jure-Kunkel, Maria; Melero, Ignacio Share Save
Dose escalation of subcutaneous epcoritamab in patients with relapsed or refractory B-cell non-Hodgkin lymphoma: an open-label, phase 1/2 study Hutchings, Martin; Mous, Rogier; Clausen, Michael Roost; Johnson, Peter; Linton, Kim M.; Chamuleau, Martine E. D.; Lewis, David John; Balari, Anna Sureda; Cunningham, David; Oliveri, Roberto S.; Elliott, Brian; DeMarco, Dena; Azaryan, Ada; Chiu, Christopher; Li, Tommy; Chen, Kuo-mei; Ahmadi, Tahamtan; Lugtenburg, Pieternella J. Share Save
Daratumumab-Based Treatment for Immunoglobulin Light-Chain Amyloidosis Kastritis, E.; Palladini, G.; Minnema, M. C.; Wechalekar, A. D.; Jaccard, A.; Lee, H. C.; Sanchorawala, V; Gibbs, S.; Mollee, P.; Venner, C. P.; Lu, J.; Schonland, S.; Gatt, M. E.; Suzuki, K.; Kim, K.; Cibeira, M. T.; Beksac, M.; Libby, E.; Valent, J.; Hungria, V; Wong, S. W.; Rosenzweig, M.; Bumma, N.; Huart, A.; Dimopoulos, M. A.; Bhutani, D.; Waxman, A. J.; Goodman, S. A.; Zonder, J. A.; Lam, S.; Song, K.; Hansen, T.; Manier, S.; Roeloffzen, W.; Jamroziak, K.; Kwok, F.; Shimazaki, C.; Kim, J-S; Crusoe, E.; Ahmadi, T.; Tran, N. P.; Qin, X.; Vasey, S. Y.; Tromp, B.; Schecter, J. M.; Weiss, B. M.; Zhuang, S. H.; Vermeulen, J.; Merlini, G.; Comenzo, R. L. Share Save
Phase I/IIa trial evaluating safety and clinical activity of DuoBody®-PD-L134-1BB (GEN1046) in advanced solid tumors Melero, Ignacio; Geva, Ravit; Ben-Ami, Eytan; Maurice-Dror, Corinne; Calvo, Emiliano; LoRusso, Patricia; Tureci, Ozlem; Niewood, Michelle; Sahin, Ugur; Jure-Kunkel, Maria; Forssmann, Ulf; Ahmadi, Tahamtan; Alonso, Guzman Share Save
HexaBody-DR5/DR5 (GEN1029) shows potent preclinical antitumor activity in a variety of patient-derived xenograft (PDX) tumor models Overdijk, Marije B.; Cecchini, Michael; Strumane, Kristin; Brandhorst, Marcel; Lingnau, Andreas; Parren, Paul W. H. I.; Ellekilde-Pedersen, Merete; Forssmann, Ulf; Ahmadi, Tahamtan; Sasser, A. Kate; Schuurman, Janine; Breij, Esther C. W.; LoRusso, Patricia Share Save
Bortezomib, thalidomide, and dexamethasone with or without daratumumab before and after autologous stem-cell transplantation for newly diagnosed multiple myeloma (CASSIOPEIA): a randomised, open-label, phase 3 study Moreau, Philippe; Attal, Michel; Hulin, Cyrille; Arnulf, Bertrand; Belhadj, Karim; Benboubker, Lotfi; Bene, Marie C.; Broijl, Annemiek; Caillon, Helene; Caillot, Denis; Corre, Jill; Delforge, Michel; Dejoie, Thomas; Doyen, Chantal; Facon, Thierry; Sonntag, Cecile; Fontan, Jean; Garderet, Laurent; Jie, Kon-Siong; Karlin, Lionel; Kuhnowski, Frederique; Lambert, Jerome; Leleu, Xavier; Lenain, Pascal; Macro, Margaret; Mathiot, Claire; Orsini-Piocelle, Frederique; Perrot, Aurore; Stoppa, Anne-Marie; van de Donk, Niels W. C. J.; Wuilleme, Soraya; Zweegman, Sonja; Kolb, Brigitte; Touzeau, Cyrille; Roussel, Murielle; Tiab, Mourad; Marolleau, Jean-Pierre; Meuleman, Nathalie; Vekemans, Marie-Christiane; Westerman, Matthijs; Klein, Saskia K.; Levin, Mark-David; Fermand, Jean Paul; Escoffre-Barbe, Martine; Eveillard, Jean-Richard; Garidi, Reda; Ahmadi, Tahamtan; Zhuang, Sen; Chiu, Christopher; Pei, Lixia; de Boer, Carla; Smith, Elena; Deraedt, William; Kampfenkel, Tobias; Schecter, Jordan; Vermeulen, Jessica; Avet-Loiseau, Herve; Sonneveld, Pieter Share Save
Daratumumab plus Lenalidomide and Dexamethasone for Untreated Myeloma Facon, T.; Kumar, S.; Plesner, T.; Orlowski, R. Z.; Moreau, P.; Bahlis, N.; Basu, S.; Nahi, H.; Hulin, C.; Quach, H.; Goldschmidt, H.; O'Dwyer, M.; Perrot, A.; Venner, C. P.; Weisel, K.; Mace, J. R.; Raje, N.; Attal, M.; Tiab, M.; Macro, M.; Frenzel, L.; Leleu, X.; Ahmadi, T.; Chiu, C.; Wang, J.; Van Rampelbergh, R.; Uhlar, C. M.; Kobos, R.; Qi, M.; Usmani, S. Z. Share Save
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