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Richard Klemke

Pacific Northwest National Laboratory

46H-index
1.2KPaper Count
1.1WCitation Count
Published Papers 52
Publication Date
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The urokinase receptor/uPAR is a major effector of p53 gain-of-function mutations in gemcitabine-treated pancreatic ductal adenocarcinoma
errJournal of Biological Chemistry
IF3.9
err2025-08-05
err0
errOAAI
errCarlotta Zampieri; Kourosh Kouhmareh; Parnian Sartipdolagh; Pardis Azmoon; Richard L. Klemke; Steven L. Gonias
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S100A8/A9 innate immune signaling as a distinct mechanism driving progression of smoking-related breast cancers
errONCOGENE
IF7.3
err2025-01-25
err0
errOAAI
errMugisha, Samson; Baba, Shahnawaz A.; Labhsetwar, Shreyas; Dave, Devam; Zakeri, Aran; Klemke, Richard; Desgrosellier, Jay S.
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Development of 3D-iNET ORION: a novel, pre-clinical, three-dimensional in vitro cell model for modeling human metastatic neuroendocrine tumor of the pancreas
errHUMAN CELL
IF3.1
err2024-08-05
err0
errOAAI
errStrnadel, Jan; Valasek, Mark A.; Lin, Grace Y.; Lin, Huahui; Tipps, Ann M. Ponsford; Woo, Sang Myung; Fujimura, Ken; Wang, Huawei; Choi, Sunkyu; Bui, Jack; Hermosillo, Christopher; Jepsen, Kristen; Navarro, Michael R.; Kelber, Jonathan A.; Klemke, Richard L.; Bouvet, Michael
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Key antiviral response genes mediate the impact of chromosomal instability on breast cancer stemness
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errBaba, Shahnawaz A.; Mugisha, Samson; Labhsetwar, Shreyas; Klemke, Richard; Desgrosellier, Jay
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errSave
Chronic use of tobacco products promotes breast cancer progression through α7 nAChR/STING pathway activation
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errMugisha, Samson; Baba, Shahnawaz; Labhsetwar, Shreyas; Klemke, Richard; Desgrosellier, Jay
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errSave
Breast cancer stem cells tolerate chromosomal instability during tumor progression via c-Jun/AXL stress signaling
errCANCER RESEARCH
IF16.6
err2024-02-01
err0
PREAI
errBaba, Shahnawaz A.; Sun, Qi; Mugisha, Samson; Labhsetwar, Shreyas; Klemke, Richard; Desgrosellier, Jay S.
errShare
errSave
Breast cancer stem cells tolerate chromosomal instability during tumor progression via c-Jun/AXL stress signaling
errHELIYON
IF3.6
err2023-09-01
err4
errOAAI
errBaba, Shahnawaz A.; Sun, Qi; Mugisha, Samson; Labhsetwar, Shreyas; Klemke, Richard; Desgrosellier, Jay S.
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errSave
Genetically engineered and enucleated human mesenchymal stromal cells for the targeted delivery of therapeutics to diseased tissue
errNATURE BIOMEDICAL ENGINEERING
IF26.6
err2021-12-20
err66
errOAAI
errWang, Huawei; Alarcon, Christina N.; Liu, Bei; Watson, Felicia; Searles, Stephen; Lee, Calvin K.; Keys, Jeremy; Pi, Willie; Allen, Dale; Lammerding, Jan; Bui, Jack D.; Klemke, Richard L.
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errSave
The Heparan Sulfate Binding Peptide in Tumor Progression of Triple-Negative Breast Cancer
errFRONTIERS IN ONCOLOGY
IF3.3
err2021-08-04
err3
errOAAI
errMelo, Carina Mucciolo; Wang, Huawei; Fujimura, Ken; Strnadel, Jan; Meneghetti, Maria Cecilia Zorel; Nader, Helena Bonciani; Klemke, Richard L.; Pinhal, Maria Aparecida Silva
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errSave
Cargocytes: A novel cell therapy platform to drive anti-tumor immunity
errCANCER RESEARCH
IF16.6
err2019-07-01
err0
PREAI
errKlemke, Richard L.; Wang, Huawei; Liu, Bei; Alarcon, Christina; Watson, Felicia
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errSave
Pseudopodium-enriched atypical kinase 1 mediates angiogenesis by modulating GATA2-dependent VEGFR2 transcription
errCELL DISCOVERY
IF12.5
err2018-05-29
err19
errOAAI
errWang, Huawei; Lapek, John; Fujimura, Ken; Strnadel, Jan; Liu, Bei; Gonzalez, David J.; Zhang, Wei; Watson, Felicia; Yu, Vicky; Liu, Chao; Melo, Carina Muccilo; Miller, Yury I.; Elliott, Kathryn C.; Cheresh, David A.; Klemke, Richard L.
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errSave
Lipoprotein lipase regulates hematopoietic stem progenitor cell maintenance through DHA supply
errNATURE COMMUNICATIONS
IF15.7
err2018-04-03
err32
errOAAI
errLiu, Chao; Han, Tianxu; Stachura, David L.; Wang, Huawei; Vaisman, Boris L.; Kim, Jungsu; Klemke, Richard L.; Remaley, Alan T.; Rana, Tariq M.; Traver, David; Miller, Yury I.
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errSave
KRAS Oncoprotein Expression Is Regulated by a Self-Governing eIF5A-PEAK1 Feed-Forward Regulatory Loop
errCANCER RESEARCH
IF16.6
err2018-03-14
err23
errOAAI
errFujimura, Ken; Wang, Huawei; Watson, Felicia; Klemke, Richard L.
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errSave
The Urokinase Receptor Induces a Mesenchymal Gene Expression Signature in Glioblastoma Cells and Promotes Tumor Cell Survival in Neurospheres
errSCIENTIFIC REPORTS
IF3.9
err2018-02-14
err50
errOAAI
errGilder, Andrew S.; Natali, Letizia; Van Dyk, Danielle M.; Zalfa, Cristina; Banki, Michael A.; Pizzo, Donald P.; Wang, Huawei; Klemke, Richard L.; Mantuano, Elisabetta; Gonias, Steven L.
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errSave
ADAMTS-1 disrupts HGF/c-MET signaling and HGF-stimulated cellular processes in fibrosarcoma
errEXPERIMENTAL CELL RESEARCH
IF3.5
err2018-02-01
err11
PREAI
errNoriega-Guerra, Heydi; Cruz, Mario C.; Ribeiro, Priscilla R. L.; Strnadel, Jan; Wan, Huawei; Klemke, Richard L.; Jaeger, Ruy G.; Freitas, Vanessa M.
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errSave
A PEAK1/GATA2 signaling axis controls VEGFR2 expression to mediate angiogenesis
errCANCER RESEARCH
IF16.6
err2017-07-01
err0
PREAI
errKlemke, Richard L.
errShare
errSave
eIF5A-PEAK1 Signaling Regulates YAP1/TAZ Protein Expression and Pancreatic Cancer Cell Growth
errCANCER RESEARCH
IF16.6
err2017-04-13
err62
errOAAI
errStrnadel, Jan; Choi, Sunkyu; Fujimura, Ken; Wang, Huawei; Zhang, Wei; Wyse, Meghan; Wright, Tracy; Gross, Emilie; Peinado, Carlos; Park, Hyun Woo; Bui, Jack; Kelber, Jonathan; Bouvet, Michael; Guan, Kun-Liang; Klemke, Richard L.
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errSave
Eukaryotic Translation Initiation Factor 5A (EIF5A) Regulates Pancreatic Cancer Metastasis by Modulating RhoA and Rho-associated Kinase (ROCK) Protein Expression Levels
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2015-12-01
err67
errOAAI
errFujimura, Ken; Choi, Sunkyu; Wyse, Meghan; Strnadel, Jan; Wright, Tracy; Klemke, Richard
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errSave
Proteomic Analysis Reveals a Role for Bcl2-associated Athanogene 3 and Major Vault Protein in Resistance to Apoptosis in Senescent Cells by Regulating ERK1/2 Activation
errMOLECULAR & CELLULAR PROTEOMICS
IF5.5
err2015-01-01
err32
errOAAI
errPasillas, Martina P.; Shields, Sarah; Reilly, Rebecca; Strnadel, Jan; Behl, Christian; Park, Robin; Yates, John R., III; Klemke, Richard; Gonias, Steven L.; Coppinger, Judith A.
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errSave
A Hypusine-eIF5A-PEAK1 Switch Regulates the Pathogenesis of Pancreatic Cancer
errCANCER RESEARCH
IF16.6
err2014-11-13
err89
errOAAI
errFujimura, Ken; Wright, Tracy; Strnadel, Jan; Kaushal, Sharmeela; Metildi, Cristina; Lowy, Andrew M.; Bouvet, Michael; Kelber, Jonathan A.; Klemke, Richard L.
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Research Directions

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