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Jane B. Trepel

national institutes of health (nih) - usa

88H-index
662Paper Count
2.5WCitation Count
Published Papers 128
Publication Date
An update on the status of HSP90 inhibitors in cancer clinical trials
err2024-08-01
err16
errOAAI
errRastogi, Shraddha; Joshi, Abhinav; Sato, Nahoko; Lee, Sunmin; Lee, Min -Jung; Trepel, Jane B.; Neckers, Len
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Tofacitinib to prevent anti-drug antibody formation against LMB-100 immunotoxin in patients with advanced mesothelin-expressing cancers
err2024-04-19
err0
errOAAI
errSkorupan, Nebojsa; Peer, Cody J.; Zhang, Xianyu; Choo-Wosoba, Hyoyoung; Ahmad, Mehwish I.; Lee, Min-Jung; Rastogi, Shraddha; Sato, Nahoko; Yu, Yunkai; Pegna, Guillaume Joe; Steinberg, Seth M.; Kalsi, Shelley S.; Cao, Liang; Figg, William D.; Trepel, Jane B.; Pastan, Ira; Fitzgerald, David; Alewine, Christine
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The CHK1 inhibitor prexasertib in BRCA wild-type platinum-resistant recurrent high-grade serous ovarian carcinoma: a phase 2 trial
err2024-03-30
err8
errOAAI
errGiudice, Elena; Huang, Tzu-Ting; Nair, Jayakumar R.; Zurcher, Grant; Mccoy, Ann; Nousome, Darryl; Radke, Marc R.; Swisher, Elizabeth M.; Lipkowitz, Stanley; Ibanez, Kristen; Donohue, Duncan; Malys, Tyler; Lee, Min-Jung; Redd, Bernadette; Levy, Elliot; Rastogi, Shraddha; Sato, Nahoko; Trepel, Jane B.; Lee, Jung-Min
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Phase I trial of avβ3 integrin cytotoxin ProAgio in patients with previously treated advanced pancreatic cancer and other solid tumor malignancies
err2023-12-01
err0
PREAI
errSkorupan, Nebojsa; Peer, Cody J.; Koehler, Eve; Steinberg, Seth; Trepel, Jane B.; Figg, William D.; Liu, Zhi-Ren; Alewine, Christine
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Structural and functional complexity of HSP90 in cellular homeostasis and disease
err2023-07-31
err45
errOAAI
errChiosis, Gabriela; Digwal, Chander S.; Trepel, Jane B.; Neckers, Len
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CellMinerCDB: NCATS Is a Web-Based Portal Integrating Public Cancer Cell Line Databases for Pharmacogenomic Explorations
err2023-05-04
err10
errOAAI
errReinhold, William C.; Wilson, Kelli; Elloumi, Fathi; Bradwell, Katie R.; Ceribelli, Michele; Varma, Sudhir; Wang, Yanghsin; Duveau, Damien; Menon, Nikhil; Trepel, Jane; Zhang, Xiaohu; Klumpp-Thomas, Carleen; Micheal, Samuel; Shinn, Paul; Luna, Augustin; Thomas, Craig; Pommier, Yves
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Targeting replication stress and chemotherapy resistance with a combination of sacituzumab govitecan and berzosertib: A phase I clinical trial
err2023-04-14
err0
PREAI
errAbel, Melissa L.; Takahashi, Nobukyuki; Desai, Parth; Peer, Cody; Redon, Christophe; Nichols, Samantha; Vilimas, Rasa; Lee, Min-Jung; Lee, Sunmin; Sciuto, Linda; Pinkiert, Danielle; Shelat, Meenakshi; Graham, Chante; Steinberg, Seth; Figg, William D.; Aladjem, Mirit; Trepel, Jane; Pommier, Yves; Thomas, Anish
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Fumarate Hydratase Deficiency in Renal Cancer Induces Glycolytic Addiction and Hypoxia-Inducible Transcription Factor 1α Stabilization by Glucose-Dependent Generation of Reactive Oxygen Species
err2023-03-21
err199
errOAAI
errSudarshan, Sunil; Sourbier, Carole; Kong, Hye-Sik; Block, Karen; Romero, Vladimir A. Valera; Yang, Youfeng; Galindo, Cynthia; Mollapour, Mehdi; Scroggins, Bradley; Goode, Norman; Lee, Min-Jung; Gourlay, Campbell W.; Trepel, Jane; Linehan, W. Marston; Neckers, Len
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A phase II trial of the super-enhancer inhibitor Minnelide™ in advanced refractory adenosquamous carcinoma of the pancreas
err2022-05-10
err22
errOAAI
errSkorupan, Nebojsa; Ahmad, Mehwish, I; Steinberg, Seth M.; Trepel, Jane B.; Cridebring, Derek; Han, Haiyong; Von Hoff, Daniel D.; Alewine, Christine
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Cell death-induced immunogenicity enhances chemoimmunotherapeutic response by converting immune-excluded into T-cell inflamed bladder tumors
err2022-03-28
err29
errOAAI
errNikolos, Fotis; Hayashi, Kazukuni; Hoi, Xen Ping; Alonzo, Mark Ellie; Mo, Qianxing; Kasabyan, Armine; Furuya, Hideki; Trepel, Jane; Di Vizio, Dolores; Guarnerio, Jlenia; Theodorescu, Dan; Rosser, Charles; Apolo, Andrea; Galsky, Matthew; Chan, Keith Syson
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MPAPASS software enables stitched multiplex, multidimensional EV repertoire analysis and a standard framework for reporting bead-based assays
err2022-01-01
err12
errOAAI
errWelsh, Joshua A.; Killingsworth, Bryce; Kepley, Julia; Traynor, Tim; Cook, Sean; Savage, Jason; Marte, Jenn; Lee, Min-Jung; Maeng, Hoyoung M.; Pleet, Michelle L.; Magana, Setty; Gorgens, Andre; Maire, Cecile L.; Lamszus, Katrin; Ricklefs, Franz L.; Merino, Maria J.; Linehan, W. Marston; Greten, Tim; Cooks, Tomer; Harris, Curtis C.; Apolo, Andrea; Abdel-Mageed, Asim; Ivanov, Alexander R.; Trepel, Jane B.; Roth, Matthew; Tkach, Mercedes; Milosavljevic, Aleksandar; Thery, Clotilde; LeBlanc, Amy; Berzofsky, Jay A.; Ruppin, Eytan; Aldape, Kenneth; Camphausen, Kevin; Gulley, James L.; Ghiran, Ionita; Jacobson, Steve; Jones, Jennifer C.
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Phase 1 trial of entinostat as monotherapy and combined with exemestane in Japanese patients with hormone receptor-positive advanced breast cancer
err2021-11-24
err18
errOAAI
errMasuda, Norikazu; Tamura, Kenji; Yasojima, Hiroyuki; Shimomura, Akihiko; Sawaki, Masataka; Lee, Min-Jung; Yuno, Akira; Trepel, Jane; Kimura, Ryoko; Nishimura, Yozo; Saji, Shigehira; Iwata, Hiroji
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Final results from phase I trial of cabozantinib/nivolumab (CaboNivo) alone or with ipilimumab (CaboNivoIpi) and peripheral immunity in metastatic genitourinary (mGU) tumors
err2021-09-01
err1
errOAAI
errKydd, A. R.; Lee, M-J.; Lee, S.; Rastogi, S.; Sato, N.; Cordes, L.; Ley, L.; Ortiz, O. Sierra; Wright, J. J.; Streicher, H.; Steinberg, S.; Saraiya, B.; Pal, S. K.; Lara, P. N.; Mortazavi, A.; Costello, R.; Niglio, S.; Bottaro, D.; Trepel, J.; Apolo, A. B.
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Randomized phase II trial of a first-in-human cancer cell lysate vaccine in patients with thoracic malignancies
err2021-07-01
err8
errOAAI
errZhang, Mary; Hong, Julie A.; Kunst, Tricia F.; Bond, Colleen D.; Kenney, Cara M.; Warga, Cheryl L.; Yeray, Javier; Lee, Min-Jung; Yuno, Akira; Lee, Sunmin; Miettinen, Markku; Ripley, R. Taylor; Hoang, Chuong D.; Gnjatic, Sacha; Trepel, Jane B.; Schrump, David S.
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Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer
err2021-06-23
err90
errOAAI
errRoper, Nitin; Velez, Moises J.; Chiappori, Alberto; Kim, Yoo Sun; Wei, Jun S.; Sindiri, Sivasish; Takahashi, Nobuyuki; Mulford, Deborah; Kumar, Suresh; Ylaya, Kris; Trindade, Christopher; Manukyan, Irena; Brown, Anna-Leigh; Trepel, Jane B.; Lee, Jung-Min; Hewitt, Stephen; Khan, Javed; Thomas, Anish
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Therapeutic Synergy in Esophageal Cancer and Mesothelioma Is Predicted by Dynamic BH3 Profiling
err2021-06-04
err4
errOAAI
errSurman, Deborah R.; Xu, Yuan; Lee, Min-Jung; Trepel, Jane; Brown, Kate; Ramineni, Maheshwari; Splawn, Taylor G.; Diggs, Laurence P.; Hodges, H. Courtney; Davis, Jeremy L.; Lee, Hyun-Sung; Burt, Bryan M.; Ripley, Robert Taylor
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Results from a biomarker study to accompany a phase II trial of RRx-001 with reintroduced platinum-based chemotherapy in relapsed small cell carcinoma
err2021-01-11
err10
errOAAI
errLee, Min-Jung; Tomita, Yusuke; Yuno, Akira; Lee, Sunmin; Abrouk, Nacer E.; Oronsky, Bryan; Caroen, Scott; Trepel, Jane B.
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In small cell lung cancer patients treated with RRx-001, a downregulator of CD47, decreased expression of PD-L1 on circulating tumor cells significantly correlates with clinical benefit
err2021-01-01
err15
errOAAI
errTomita, Yusuke; Oronsky, Bryan; Abrouk, Nacer; Cabrales, Pedro; Reid, Tony R.; Lee, Min-Jung; Yuno, Akira; Baker, Jonathan; Lee, Sunmin; Trepel, Jane B.
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Cabozantinib plus docetaxel and prednisone in metastatic castration-resistant prostate cancer
err2020-10-23
err9
errOAAI
errMadan, Ravi A.; Karzai, Fatima H.; Al Harthy, Munjid; Petrylak, Daniel P.; Kim, Joseph W.; Arlen, Philip M.; Rosner, Inger; Theoret, Marc R.; Cordes, Lisa; Bilusic, Marijo; Peer, Cody J.; Dawson, Nancy A.; Couvillon, Anna; Hankin, Amy; Williams, Moniquea; Chun, Guin; Owens, Helen; Marte, Jennifer L.; Lee, Min-Jung; Tomita, Yusuke; Yuno, Akira; Trepel, Jane B.; Lee, Sunmin; Steinberg, Seth M.; Gulley, James L.; Figg, William D.; Dahut, William L.
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