Not logged in Targeting specific kinase substrates rescues increased colitis severity induced by the Crohn's disease-linked LRRK2-N2081D variant Heaton, George R.; Li, Xingjian; Li, Xianting; Zhou, Xiaoting; Zhang, Yuanxi; Vu, Duc Tung; Oeller, Marc; Karayel, Ozge; Hoang, Quyen Q.; Kars, Meltem Ece; Kamath, Nitika; Wang, Minghui; Tarassishin, Leonid; Mann, Matthias; Peter, Inga; Yue, Zhenyu Share Save
Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism Gottemukkala, Karthik V.; Chrustowicz, Jakub; Sherpa, Dawafuti; Sepic, Sara; Vu, Duc Tung; Karayel, Ozge; Papadopoulou, Eleftheria C.; Gross, Annette; Schorpp, Kenji; von Gronau, Susanne; Hadian, Kamyar; Murray, Peter J.; Mann, Matthias; Schulman, Brenda A.; Alpi, Arno F. Share Save
Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies Chrustowicz, Jakub; Sherpa, Dawafuti; Li, Jerry; Langlois, Christine R.; Papadopoulou, Eleftheria C.; Vu, D. Tung; Hehl, Laura A.; Karayel, Oezge; Beier, Viola; von Gronau, Susanne; Mueller, Judith; Prabu, J. Rajan; Mann, Matthias; Kleiger, Gary; Alpi, Arno F.; Schulman, Brenda A. Share Save
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Quantitative multiorgan proteomics of fatal COVID-19 uncovers tissue-specific effects beyond inflammation Schweizer, Lisa; Schaller, Tina; Zwiebel, Maximilian; Karayel, Oezge; Mueller-Reif, Johannes Bruno; Zeng, Wen-Feng; Dintner, Sebastian; Nordmann, Thierry M.; Hirschbuehl, Klaus; Maerkl, Bruno; Claus, Rainer; Mann, Matthias Share Save
Modular UBE2H-CTLH E2-E3 complexes regulate erythroid maturation Sherpa, Dawafuti; Mueller, Judith; Karayel, Oezge; Xu, Peng; Yao, Yu; Chrustowicz, Jakub; Gottemukkala, Karthik, V; Baumann, Christine; Gross, Annette; Czarnecki, Oliver; Zhang, Wei; Gu, Jun; Nilvebrant, Johan; Sidhu, Sachdev S.; Murray, Peter J.; Mann, Matthias; Weiss, Mitchell J.; Schulman, Brenda A.; Alpi, Arno F. Share Save
Analysis of RANK-c interaction partners identifies TRAF3 as a critical regulator of breast cancer aggressiveness Sirinian, Chaido; Papanastasiou, Anastasios D.; Karayel, Ozge; Degn, Soren E.; Peroukidis, Stavros; Chaniotis, Dimitrios; Nonni, Afrodite; Repanti, Maria; Kriegsmann, Mark; Makatsoris, Thomas; Koutras, Angelos; Mann, Matthias; Kalofonos, Haralabos P. Share Save
Rapid and In-Depth Coverage of the (Phospho-) Proteome With Deep Libraries and Optimal Window Design for dia-PASEF Skowronek, Patricia; Thielert, Marvin; Voytik, Eugenia; Tanzer, Maria C.; Hansen, Fynn M.; Willems, Sander; Karayel, Ozge; Brunner, Andreas-David; Meier, Florian; Mann, Matthias Share Save
Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degra-dation of BCL11A protein in erythroid cells Mehta, Stuti; Buyanbat, Altantsetseg; Kai, Yan; Karayel, Ozge; Goldman, Seth Raphael; Seruggia, Davide; Zhang, Kevin; Fujiwara, Yuko; Donovan, Katherine A.; Zhu, Qian; Yang, Huan; Nabet, Behnam; Gray, Nathanael S.; Mann, Matthias; Fischer, Eric S.; Adelman, Karen; Orkin, Stuart H. Share Save
Proteome profiling of cerebrospinal fluid reveals biomarker candidates for Parkinson's disease Karayel, Ozge; Winter, Sebastian Virreira; Padmanabhan, Shalini; Kuras, Yuliya, I; Vu, Duc Tung; Tuncali, Idil; Merchant, Kalpana; Wills, Anne-Marie; Scherzer, Clemens R.; Mann, Matthias Share Save
Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation Qiao, Shuai; Lee, Chia-Wei; Sherpa, Dawafuti; Chrustowicz, Jakub; Cheng, Jingdong; Duennebacke, Maximilian; Steigenberger, Barbara; Karayel, Ozge; Duc Tung Vu; von Gronau, Susanne; Mann, Matthias; Wilfling, Florian; Schulman, Brenda A. Share Save
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Phosphorylation of serine-893 in CARD11 suppresses the formation and activity of the CARD11-BCL10-MALT1 complex in T and B cells Kutzner, Kerstin; Woods, Simone; Karayel, Ozge; Gehring, Torben; Yin, Hongli; Flatley, Andrew; Grass, Carina; Wimberger, Nicole; Tofaute, Marie J.; Seeholzer, Thomas; Feederle, Regina; Mann, Matthias; Krappmann, Daniel Share Save
A20 and ABIN-1 cooperate in balancing CBM complex-triggered NF-κB signaling in activated T cells Yin, Hongli; Karayel, Ozge; Chao, Ying-Yin; Seeholzer, Thomas; Hamp, Isabel; Plettenburg, Oliver; Gehring, Torben; Zielinski, Christina; Mann, Matthias; Krappmann, Daniel Share Save
GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme Sherpa, Dawafuti; Chrustowicz, Jakub; Qiao, Shuai; Langlois, Christine R.; Hehl, Laura A.; Gottemukkala, Karthik Varma; Hansen, Fynn M.; Karayel, Ozge; von Gronau, Susanne; Prabu, J. Rajan; Mann, Matthias; Alpi, Arno F.; Schulman, Brenda A. Share Save
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Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler Liwocha, Joanna; Krist, David T.; van der Heden van Noort, Gerbrand J.; Hansen, Fynn M.; Truong, Vinh H.; Karayel, Ozge; Purser, Nicholas; Houston, Daniel; Burton, Nicole; Bostock, Mark J.; Sattler, Michael; Mann, Matthias; Harrison, Joseph S.; Kleiger, Gary; Ovaa, Huib; Schulman, Brenda A. Share Save
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