Not logged in Targeting αvβ8 Integrin with mAb MEDI8367 Prevents Fibrosis in Preclinical Models of CKD Marin, Elena Liarte; Seth, Asha; Liang, Lihuan; Baker, David; Conway, James; McCarthy, Michael; Lapointe, Jean-Martin; Stebbings, Richard; Hebeis, Barbara; Hess, Sonja; Hansen, Pernille B. L.; Mulay, Shrikant R.; Woollard, Kevin J. Share Save
Regulatory T cells: a promising therapeutic strategy for AKI Petrillo, Federica; Richards, Mark; Tuffin, Jack; Garibotti, Hernan Gonzalez-King; Dearman, Matthew; Thomas, Aurelie; Seth, Asha; Williams, Julie; Hansen, Pernille B. L.; Woollard, Kevin Share Save
Targeting the Type I Interferon Pathway in Glomerular Kidney Disease: Rationale and Therapeutic Opportunities Tumlin, James; Rovin, Brad; Anders, Hans-Joachim; Mysler, Eduardo F.; Jayne, David R. W.; Takeuchi, Tsutomu; Lindholm, Catharina; Weiss, Gudrun; Sorrentino, Alessandro; Woollard, Kevin; Ferrari, Nicola Share Save
Multi-omics and imaging mass cytometry characterization of human kidneys to identify pathways and phenotypes associated with impaired kidney function Asowata, Evans O.; Romoli, Simone; Sargeant, Rebecca; Tan, Jennifer Y.; Hoffmann, Scott; Huang, Margaret M.; Mahbubani, Krishnaa T.; Krause, Fynn N.; Jachimowicz, Daniel; Agren, Rasmus; Koulman, Albert; Jenkins, Benjamin; Musial, Barbara; Griffin, Julian L.; Soderberg, Magnus; Ling, Stephanie; Hansen, Pernille B. L.; Saeb-Parsy, Kourosh; Woollard, Kevin J. Share Save
Inhibition of Interleukin-33 to Reduce Glomerular Endothelial Inflammation in Diabetic Kidney Disease Hofherr, Alexis; Marin, Elena Liarte; Musial, Barbara; Seth, Asha; Slidel, Tim; Conway, James; Baker, David; Hansen, Pernille B. L.; Challis, Benjamin; Bartesaghi, Stefano; Bhat, Maria; Pecoits-Filho, Roberto; Tu, Xiao; Selvarajah, Viknesh; Woollard, Kevin; Heerspink, Hiddo J. L. Share Save
Integrated Proteomics Characterization of NLRP3 Inflammasome Inhibitor MCC950 in Monocytic Cell Line Confirms Direct MCC950 Engagement with Endogenous NLRP3 Zhao, Heng; Kumar, Praveen; Sobreira, Tiago Jose Paschoal; Smith, Mackenzie; Novick, Steven; Johansson, Anders; Luchniak, Anna; Zhang, Andrew; Woollard, Kevin J.; Larsson, Niklas; Kawatkar, Aarti Share Save
Selective induction of human renal interstitial progenitor-like cell lineages from iPSCs reveals development of mesangial and EPO-producing cells Tsujimoto, Hiraku; Hoshina, Azusa; Mae, Shin-Ichi; Araoka, Toshikazu; Wang, Changting; Ijiri, Yoshihiro; Nakajima-Koyama, May; Sakurai, Satoko; Okita, Kazusa; Mizuta, Ken; Niwa, Akira; Saito, Megumu K.; Saitou, Mitinori; Yamamoto, Takuya; Graneli, Cecilia; Woollard, Kevin J.; Osafune, Kenji Share Save
TLR7 activation at epithelial barriers promotes emergency myelopoiesis and lung antiviral immunity Jackson, William D.; Giacomassi, Chiara; Ward, Sophie; Owen, Amber; Luis, Tiago C.; Spear, Sarah; Woollard, Kevin J.; Johansson, Cecilia; Strid, Jessica; Botto, Marina Share Save
Biphasic Dynamics of Inflammatory Markers Following Hemodialysis Initiation: Results From the International MONitoring Dialysis Outcome Initiative Yousif, Dalia E.; Ye, Xiaoling; Stuard, Stefano; Berbessi, Juan; Guinsburg, Adrian M.; Usvyat, Len A.; Raimann, Jochen G.; Kooman, Jeroen P.; van der Sande, Frank M.; Duncan, Neill; Woollard, Kevin J.; Bright, Rupert; Pusey, Charles; Gupta, Vineet; Ix, Joachim H.; Kotanko, Peter; Malhotra, Rakesh Share Save
A novel phosphocholine-mimetic inhibits a pro-inflammatory conformational change in C-reactive protein Zeller, Johannes; Shing, Karen S. Cheung Tung; Nero, Tracy L.; McFadyen, James D.; Krippner, Guy; Bogner, Balazs; Kreuzaler, Sheena; Kiefer, Jurij; Horner, Verena K.; Braig, David; Danish, Habiba; Baratchi, Sara; Fricke, Mark; Wang, Xiaowei; Kather, Michel G.; Kammerer, Bernd; Woollard, Kevin J.; Sharma, Prerna; Morton, Craig J.; Pietersz, Geoffrey; Parker, Michael W.; Peter, Karlheinz; Eisenhardt, Steffen U. Share Save
Glomerulonephritis and autoimmune vasculitis are independent of P2RX7 but may depend on alternative inflammasome pathways Prendecki, Maria; McAdoo, Stephen P.; Turner-Stokes, Tabitha; Garcia-Diaz, Ana; Orriss, Isabel; Woollard, Kevin J.; Behmoaras, Jacques; Cook, H. Terence; Unwin, Robert; Pusey, Charles D.; Aitman, Timothy J.; Tam, Frederick W. K. Share Save
Rapid target validation in a Cas9-inducible hiPSC derived kidney model Shamshirgaran, Yasaman; Jonebring, Anna; Svensson, Anna; Leefa, Isabelle; Bohlooly-Y, Mohammad; Firth, Mike; Woollard, Kevin J.; Hofherr, Alexis; Rogers, Ian M.; Hicks, Ryan Share Save
Characterisation of an enhanced preclinical model of experimental MPO-ANCA autoimmune vasculitis Prendecki, Maria; Gulati, Kavita; Turner-Stokes, Tabitha; Bhangal, Gurjeet; Chiappo, Derick; Woollard, Kevin; Cook, H. Terence; Tam, Frederick W. K.; Roufosse, Candice; Pusey, Charles D.; McAdoo, Stephen P. Share Save
Activation and transcriptional profile of monocytes and CD8+ T cells are altered in checkpoint inhibitor-related hepatitis Gudd, Cathrin L. C.; Au, Lewis; Triantafyllou, Evangelos; Shum, Benjamin; Liu, Tong; Nathwani, Rooshi; Kumar, Naveenta; Mukherjee, Sujit; Dhar, Ameet; Woollard, Kevin J.; Yone, You; Pinato, David J.; Thursz, Mark R.; Goldin, Robert D.; Gore, Martin E.; Larkin, James; Khamri, Wafa; Antoniades, Charalambos G.; Turajlic, Samra; Possamai, Lucia A. Share Save
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Selective Interleukin-6 Trans-Signaling Blockade Is More Effective Than Panantagonism in Reperfused Myocardial Infarction George, Marc Jonathan; Jasmin, Nur Hayati; Cummings, Valerie Taylor; Richard-Loendt, Angela; Launchbury, Francesca; Woollard, Kevin; Turner-Stokes, Tabitha; Diaz, Ana Isabel Garcia; Lythgoe, Mark; Stuckey, Daniel James; Hingorani, Aroon Dinesh; Gilroy, Derek William Share Save
An Unbiased Flow Cytometry-Based Approach to Assess Subset-Specific Circulating Monocyte Activation and Cytokine Profile in Whole Blood Kiefer, Jurij; Zeller, Johannes; Bogner, Balazs; Hoerbrand, Isabel A.; Lang, Friederike; Deiss, Emil; Winninger, Oscar; Fricke, Mark; Kreuzaler, Sheena; Smudde, Eva; Huber-Lang, Markus; Peter, Karlheinz; Woollard, Kevin J.; Eisenhardt, Steffen U. Share Save
High intraluminal pressure promotes vascular inflammation via caveolin-1 Michell, Danielle L.; Shihata, Waled A.; Andrews, Karen L.; Abidin, Nurul Aisha Zainal; Jefferis, Ann-Maree; Sampson, Amanda K.; Lumsden, Natalie G.; Huet, Olivier; Parat, Marie-Odile; Jennings, Garry L.; Parton, Robert G.; Woollard, Kevin J.; Kaye, David M.; Chin-Dusting, Jaye P. F.; Murphy, Andrew J. Share Save
PD-1 blockade improves Kupffer cell bacterial clearance in acute liver injury Triantafyllou, Evangelos; Gudd, Cathrin L. C.; Mawhin, Marie-Anne; Husbyn, Hannah C.; Trovato, Francesca M.; Siggins, Matthew K.; O'Connor, Thomas; Kudo, Hiromi; Mukherjee, Sujit K.; Wendon, Julia A.; Bernsmeier, Christine; Goldin, Robert D.; Botto, Marina; Khamri, Wafa; McPhail, Mark J. W.; Possamai, Lucia A.; Woollard, Kevin J.; Antoniades, Charalambos G.; Thursz, Mark R. Share Save
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