Not logged in VirTac, a modular lentiviral-based platform, elicits selective and marked expansion of HIV-, CMV- and SARS-CoV-2-specific T cell responses, validating its applications for adoptive T cell therapies Bravo, Marta Santos; Cole, Erin; Mueller, April; Hiner, Christopher; Syndenstricker, Agnes; Voss, Adilyn; Hua, Jian; Garforth, Scott; Almo, Steven; Goldstein, Harris Share Save
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Unique mechanisms to increase structural stability and enhance antigen binding in nanobodies Ketaren, Natalia E.; Fridy, Peter C.; Malashkevich, Vladimir; Sanyal, Tanmoy; Brillantes, Marc; Thompson, Mary K.; Oren, Deena A.; Bonanno, Jeffrey B.; Sali, Andrej; Almo, Steven C.; Chait, Brian T.; Rout, Michael P. Share Save
Structural and biochemical analysis of highly similar HLA-B allotypes differentially associated with type 1 diabetes Sharma, Ruby; Amdare, Nitin P.; Ghosh, Agnidipta; Schloss, Jennifer; Sidney, John; Garforth, Scott J.; Lopez, Yessenia; Celikgil, Alev; Sette, Alessandro; Almo, Steven C.; Dilorenzo, Teresa P. Share Save
A hemoprotein with a zinc-mirror heme site ties heme availability to carbon metabolism in cyanobacteria Grosjean, Nicolas; Yee, Estella F.; Kumaran, Desigan; Chopra, Kriti; Abernathy, Macon; Biswas, Sandeep; Byrnes, James; Kreitler, Dale F.; Cheng, Jan-Fang; Ghosh, Agnidipta; Almo, Steven C.; Iwai, Masakazu; Niyogi, Krishna K.; Pakrasi, Himadri B.; Sarangi, Ritimukta; van Dam, Hubertus; Yang, Lin; Blaby, Ian K.; Blaby-Haas, Crysten E. Share Save
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Integrative Molecular Structure Elucidation and Construction of an Extended Metabolic Pathway Associated with an Ancient Innate Immune Response in COVID-19 Patients Sala, Samuele; Nitschke, Philipp; Masuda, Reika; Gray, Nicola; Lawler, Nathan G.; Wood, James M.; Buckler, Joshua N.; Berezhnoy, Georgy; Bolanos, Jose; Boughton, Berin A.; Lonati, Caterina; Roessler, Titus; Singh, Yogesh; Wilson, Ian D.; Lodge, Samantha; Morillon, Aude-Claire; Loo, Ruey Leng; Hall, Drew; Whiley, Luke; Evans, Gary B.; Grove, Tyler L.; Almo, Steven C.; Harris, Lawrence D.; Holmes, Elaine; Merle, Uta; Trautwein, Christoph; Nicholson, Jeremy K.; Wist, Julien Share Save
Discovery of a Biotin Synthase That Utilizes an Auxiliary 4Fe-5S Cluster for Sulfur Insertion Lachowicz, Jake C.; Lennox-Hvenekilde, David; Myling-Petersen, Nils; Salomonsen, Bo; Verkleij, Gijs; Acevedo-Rocha, Carlos G.; Caddell, Ben; Gronenberg, Luisa S.; Almo, Steven C.; Sommer, Morten O. A.; Genee, Hans J.; Grove, Tyler L. Share Save
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Two point mutations in protocadherin-1 disrupt hantavirus recognition and afford protection against lethal infection (vol 14, 4454, 2023) Slough, Megan M.; Li, Rong; Herbert, Andrew S.; Lasso, Gorka; Kuehne, Ana I.; Monticelli, Stephanie R.; Bakken, Russell R.; Liu, Yanan; Ghosh, Agnidipta; Moreau, Alicia M.; Zeng, Xiankun; Rey, Felix A.; Guardado-Calvo, Pablo; Almo, Steven C.; Dye, John M.; Jangra, Rohit K.; Wang, Zhongde; Chandran, Kartik Share Save
Cell-impermeable staurosporine analog targets extracellular kinases to inhibit HSV and SARS-CoV-2 (vol 5, 1096, 2022) Cheshenko, Natalia; Bonanno, Jeffrey B. B.; Hoffmann, Hans-Heinrich; Jangra, Rohit K. K.; Chandran, Kartik; Rice, Charles M. M.; Almo, Steven C. C.; Herold, Betsy C. C. Share Save
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Two point mutations in protocadherin-1 disrupt hantavirus recognition and afford protection against lethal infection Slough, Megan M.; Li, Rong; Herbert, Andrew S.; Lasso, Gorka; Kuehne, Ana I.; Monticelli, Stephanie R.; Bakken, Russell R.; Liu, Yanan; Ghosh, Agnidipta; Moreau, Alicia M.; Zeng, Xiankun; Rey, Felix A.; Guardado-Calvo, Pablo; Almo, Steven C.; Dye, John M.; Jangra, Rohit K.; Wang, Zhongde; Chandran, Kartik Share Save
A non-neutralizing glycoprotein B monoclonal antibody protects against herpes simplex virus disease in mice Kuraoka, Masayuki; Aschner, Clare Burn; Windsor, Ian W.; Mahant, Aakash Mahant; Garforth, Scott J.; Kong, Susan Luozheng; Achkar, Jacqueline M.; Almo, Steven C.; Kelsoe, Garnett; Herold, Betsy C. Share Save
Human immunomodulatory ligand B7-1 mediates synaptic remodeling via the p75 neurotrophin receptor br Morano, Nicholas C.; Smith, Roshelle S.; Danelon, Victor; Schreiner, Ryan; Patel, Uttsav; Herrera, Natalia G.; Smith, Carla; Olson, Steven M.; Laerke, Michelle K.; Celikgil, Alev; Garforth, Scott J.; Garrett-Thomson, Sarah C.; Lee, Francis S.; Hempstead, Barbara L.; Almo, Steven C. Share Save
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A glycan-based approach to cell characterization and isolation: Hematopoiesis as a paradigm Piszczatowski, Richard T.; Schwenger, Emily; Sundaravel, Sriram; Stein, Catarina M.; Liu, Yang; Stanley, Pamela; Verma, Amit; Zheng, Deyou; Seidel, Ronald D.; Almo, Steven C.; Townley, Robert A.; Buelow, Hannes E.; Steidl, Ulrich Share Save
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Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication Hsu, Jack Chun-Chieh; Laurent-Rolle, Maudry; Pawlak, Joanna B.; Xia, Hongjie; Kunte, Amit; Hee, Jia Shee; Lim, Jaechul; Harris, Lawrence D.; Wood, James M.; Evans, Gary B.; Shi, Pei-Yong; Grove, Tyler L.; Almo, Steven C.; Cresswell, Peter Share Save