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D

Donald E. Kohan

University of Utah Health

60H-index
319Paper Count
1.4WCitation Count
Published Papers 142
Publication Date
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Podocyte derived endothelin-1 and endothelial cell endothelin A receptors are essential for glomerular injury in mouse models of focal segmental glomerulosclerosis.
errKidney International
IF12.6
err2026-02-09
err0
errOAAI
errLiping Yu; Ubong S. Ekperikpe; Hunter W. Korsmo; Serena Zhao; Zhengzi Yi; Jonathan Haydak; Sean Lefferts; Kristin Meliambro; Kirk N. Campbell; Evren U. Azeloglu; Donald E. Kohan; Phillip J. McCown; Abhijit S. Naik; Edgar A. Otto; Börje Haraldsson; Weijia Zhang; Ilse S. Daehn
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ALIGN post-hoc analyses: Reduction in proteinuria with atrasentan across subgroups by MEST-C score, baseline hematuria and baseline UPCR
errNephrology Dialysis Transplantation
IF5.6
err2025-10-01
err0
errOAAI
errHeerspink, Hiddo J. L.; Jardine, Meg; Kohan, Donald; Lafayette, Richard; Levin, Adeera; Liew, Adrian; Zhang, Hong; Davies, Helen Twiston; Knorr, Barbara; Ansari, Soudeh; Renfurm, Ronny; Barratt, Jonathan
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The dual endothelin A and angiotensin II type 1 receptor antagonist sparsentan (FILSPARI®) exhibits a safe nonclinical male fertility toxicity profile
errREGULATORY TOXICOLOGY AND PHARMACOLOGY
IF3.5
err2025-02-01
err0
errOAAI
errBedard, Patricia W.; Pretto, Francesca; Patel, Sima; Jenkinson, Celia; White, Tacey; Kohan, Donald E.
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Study Design and Baseline Characteristics of ALIGN, a Randomized Controlled Study of Atrasentan in Patients With IgA Nephropathy
errKIDNEY INTERNATIONAL REPORTS
IF5.7
err2025-01-01
err1
errOAAI
errHeerspink, Hiddo J. L.; Jardine, Meg; Kohan, Donald E.; Lafayette, Richard A.; Levin, Adeera; Liew, Adrian; Zhang, Hong; Noronha, Irene; Trimarchi, Hernan; Hou, Fan Fan; Renfurm, Ronny; Gray, Todd; Camargo, Marianne; Barratt, Jonathan
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Sex differences in response to the endothelin receptor antagonist atrasentan in individuals with type 2 diabetes and chronic kidney disease: a post hoc analysis of the SONAR trial
errDIABETOLOGIA
IF10.2
err2024-12-11
err0
PREAI
errSmeijer, J. David; de Vries, Sieta T.; Kohan, Donald E.; Hou, Fan Fan; Heerspink, Hiddo J. L.
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Endothelin receptor antagonists in chronic kidney disease
errNATURE REVIEWS NEPHROLOGY
IF39.8
err2024-12-06
err0
PREAI
errSmeijer, J. David; Kohan, Donald E.; Dhaun, Neeraj; Noronha, Irene L.; Liew, Adrian; Heerspink, Hiddo J. L.
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Mechanism of protective actions of sparsentan in the kidney: lessons from studies in models of chronic kidney disease
errCLINICAL SCIENCE
IF7.7
err2024-05-29
err3
errOAAI
errKohan, Donald E.; Bedard, Patricia W.; Jenkinson, Celia; Hendry, Bruce; Komers, Radko
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Sparsentan versus Irbesartan in Focal Segmental Glomerulosclerosis
errNEW ENGLAND JOURNAL OF MEDICINE
IF78.5
err2023-12-28
err34
PREAI
errRheault, Michelle N.; Alpers, Charles E.; Barratt, Jonathan; Bieler, Stewart; Canetta, Pietro; Chae, Dong-Wan; Coppock, Gaia; Diva, Ulysses; Gesualdo, Loreto; Heerspink, Hiddo J. L.; Inrig, Jula K.; Kirsztajn, Gianna M.; Kohan, Donald; Komers, Radko; Kooienga, Laura A.; Lieberman, Kenneth; Mercer, Alex; Noronha, Irene L.; Perkovic, Vlado; Radhakrishnan, Jai; Rote, William; Rovin, Brad; Tesar, Vladimir; Trimarchi, Hernan; Tumlin, James; Wong, Muh Geot; Trachtman, Howard
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Post hoc analysis of the SONAR trial indicates that the endothelin receptor antagonist atrasentan is associated with less pain in patients with type 2 diabetes and chronic kidney disease
errKIDNEY INTERNATIONAL
IF12.6
err2023-12-01
err8
errOAAI
errChan, Kam Wa; Smeijer, J. David; Schechter, Meir; Jongs, Niels; Vart, Priya; Kohan, Donald E.; Gansevoort, Ron T.; Liew, Adrian; Tang, Sydney C. W.; Wanner, Christoph; de Zeeuw, Dick; Heerspink, Hiddo J. L.
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Efficacy and safety of sparsentan versus irbesartan in patients with IgA nephropathy (PROTECT): 2-year results from a randomised, active-controlled, phase 3 trial
errLANCET
IF88.5
err2023-12-01
err75
PREAI
errRovin, Brad H.; Barratt, Jonathan; Heerspink, Hiddo J. L.; Alpers, Charles E.; Bieler, Stewart; Chae, Dong-Wan; Diva, Ulysses A.; Floege, Juergen; Gesualdo, Loreto; Inrig, Jula K.; Kohan, Donald E.; Komers, Radko; Kooienga, Laura Ann; Lafayette, Richard; Maes, Bart; Malecki, Robert; Mercer, Alex; Noronha, Irene L.; Oh, Se Won; Peh, Chen Au; Praga, Manuel; Preciado, Priscila; Radhakrishnan, Jai; Rheault, Michelle N.; Rote, William E.; Tang, Sydney C. W.; Tesar, Vladimir; Trachtman, Howard; Trimarchi, Hernan; Tumlin, James A.; Wong, Muh Geot; Perkovic, Vlado
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errSave
Targeting the Endothelin A Receptor in IgA Nephropathy
errKIDNEY INTERNATIONAL REPORTS
IF5.7
err2023-11-01
err17
errOAAI
errKohan, Donald E.; Barratt, Jonathan; Heerspink, Hiddo J.; Campbell, Kirk N.; Camargo, Mariannne; Ogbaa, Ike; Haile-Meskale, Ruth; Rizk, Dana V.; King, Andrew
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Insulin resistance, kidney outcomes and effects of the endothelin receptor antagonist atrasentan in patients with type 2 diabetes and chronic kidney disease
errCARDIOVASCULAR DIABETOLOGY
IF10.6
err2023-09-16
err13
errOAAI
errSmeijer, J. David; Kohan, Donald E.; Rossing, Peter; Correa-Rotter, Ricardo; Liew, Adrian; Tang, Sydney C. W.; de Zeeuw, Dick; Gansevoort, Ron T.; Ju, Wenjun; Heerspink, Hiddo J. Lambers
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Diuretic medication and change in fluid retention biomarkers during treatment with the endothelin receptor antagonist atrasentan
errDIABETES OBESITY & METABOLISM
IF5.7
err2023-05-08
err0
errOAAI
errSmeijer, J. David; Kohan, Donald E.; de Zeeuw, D.; Heerspink, Hiddo J. L.
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Effects of atrasentan on markers of liver function in patients with type 2 diabetes and chronic kidney disease
errDIABETES OBESITY & METABOLISM
IF5.7
err2023-05-04
err6
errOAAI
errKohan, Donald E.; Liew, Adrian; Tang, Sydney C. W.; Barratt, Jonathan; Heerspink, Hiddo J. L.
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Fluid retention and heart failure in the PRECISION trial
errLANCET
IF88.5
err2023-04-01
err2
PREAI
errKohan, Donald E.; Heerspink, Hiddo J. L.
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Progenitor-derived endothelin controls dermal sheath contraction for hair follicle regression
errNATURE CELL BIOLOGY
IF19.1
err2023-01-30
err10
errOAAI
errMartino, Pieter; Sunkara, Raghava; Heitman, Nicholas; Rangl, Martina; Brown, Alexia; Saxena, Nivedita; Grisanti, Laura; Kohan, Donald; Yanagisawa, Masashi; Rendl, Michael
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Organic Anion Transporter Gene Variants Associated with Plasma Exposure and Long-Term Response to Atrasentan in Patients With Diabetic Kidney Disease
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2022-08-11
err4
errOAAI
errSmeijer, J. David; Koomen, Jeroen, V; Kohan, Donald E.; McMurray, John J., V; Bakris, George L.; Correa-Rotter, Ricardo; Hou, Fan-Fan; Kitzman, Dalane W.; Makino, Hirofumi; Mayer, Gert; Nowicki, Michal; Perkovic, Vlado; Rossing, Peter; Tobe, Sheldon; Parving, Hans-Henrik; de Zeeuw, Dick; Heerspink, Hiddo J. L.
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Multiomic identification of factors associated with progression to cystic kidney disease in mice with nephron Ift88 disruption
errAMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
IF3.4
err2022-02-01
err3
errOAAI
errHu, Chunyan; Beebe, Katherine; Hernandez, Edgar J.; Lazaro-Guevara, Jose M.; Revelo, Monica P.; Huang, Yufeng; Maschek, J. Alan; Cox, James E.; Kohan, Donald E.
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The Effect of Atrasentan on Kidney and Heart Failure Outcomes by Baseline Albuminuria and Kidney Function A Post Hoc Analysis of the SONAR Randomized Trial
errCLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
IF7.1
err2021-12-01
err16
errOAAI
errWaijer, Simke W.; Gansevoort, Ron T.; Bakris, George L.; Correa-Rotter, Ricardo; Hou, Fan-Fan; Kohan, Donald E.; Kitzman, Dalane W.; Makino, Hirofumi; McMurray, John J. V.; Perkovic, Vlado; Tobe, Sheldon; Parving, Hans-Henrik; de Zeeuw, Dick; Heerspink, Hiddo J. L.
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Loss of Soluble (Pro)renin Receptor Attenuates Angiotensin-II Induced Hypertension and Renal Injury
errCIRCULATION RESEARCH
IF16.2
err2021-06-25
err23
errOAAI
errRamkumar, Nirupama; Stuart, Deborah; Peterson, Caitlin S.; Hu, Chunyan; Wheatley, William; Cho, Jae Min; Symons, J. David; Kohan, Donald E.
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Research Directions

No research directions
Co-authors
Cooperation Journals
J
John J.V. McMurray
H-index: 231 · Papers: 2.6K
G
Giuseppe Remuzzi
H-index: 201 · Papers: 2.1K
F
Frank J. Gonzalez
H-index: 191 · Papers: 1.7K
J
John G.F. Cleland
H-index: 175 · Papers: 2.2K
G
George L. Bakris
H-index: 147 · Papers: 1.4K
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