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KRAS mutation detection by liquid biopsy for pancreatic ductal adenocarcinoma Yousef, Mahmoud; Yousef, Abdelrahman; Hurd, Mark W.; Pillai, Ashwathy; Chowdhury, Saikat; Snyder, Rebecca; Knafl, Mark; Lewis, Ryan L.; Roy, Paul M.; Fanaeian, Mohammad; Albarouki, Sali; Castelnovo, Luca F.; Peterson, Jennifer; Smaglo, Brandon G.; Wolff, Robert A.; Pant, Shubham; Willis, Jason; Huey, Ryan; Overman, Michael; Tzeng, Ching-Wei; Kim, Michael P.; Ikoma, Naruhiko; Maxwell, Jess E.; Katz, Matthew H. G.; Wang, Huamin; Maitra, Anirban; Koay, Eugene; Ludmir, Ethan B.; Chen, Anthony; Lopez, Camila; Ying, Haoqiang; Shen, John Paul; Zhao, Dan Share Save
A rigorous multi-laboratory study of known PDAC biomarkers identifies increased sensitivity and specificity over CA19-9 alone Haab, Brian; Qian, Lu; Staal, Ben; Jain, Maneesh; Fahrmann, Johannes; Worthington, Christine; Prosser, Denise; Velokokhatnaya, Liudmila; Lopez, Camden; Tang, Runlong; Hurd, Mark W.; Natarajan, Gopalakrishnan; Kumar, Sushil; Smith, Lynette; Hanash, Sam; Batra, Surinder K.; Maitra, Anirban; Lokshin, Anna; Huang, Ying; Brand, Randall E. Share Save
Disruption of sulfatide metabolism by targeting UGT8 is an actionable metabolic vulnerability for pancreatic cancer early interception Ballaro, Riccardo; Chen, Yihui; Thege, Fredrik I.; Dou, Rongzhang; Min, Jimin; Yip-Schneider, Michele; Zhang, Jianjun; Wu, Ranran; Irajizad, Ehsan; Makino, Yuki; Rajapakshe, Kimal I.; Hurd, Mark W.; Leon-Letelier, Ricardo A.; Ostrin, Edwin; Vykoukal, Jody; Dennison, Jennifer B.; Do, Kim-Anh; Hanash, Samir; Wolff, Robert A.; Guerrero, Paola A.; Kim, Michael P.; Schmidt, C. Max; Maitra, Anirban; Fahrmann, Johannes F. Share Save
KRAS Q61 mutations in patients with gastrointestinal malignancies and association with real-world clinical outcomes Yousef, Mahmoud; Yousef, Abdelrahman; Chowdhury, Saikat; Fanaeian, Mohammad Mahdi; Knafl, Mark; Roy, Paul M.; Pillai, Ashwathy; Zeineddine, Mohammad; Zeineddine, Fadl; Peterson, Jennifer; Smaglo, Brandon G.; Wolff, Robert A.; Pant, Shubham; Lee, Michael Sangmin; Willis, Jason A.; Overman, Michael James; Ludmir, Ethan Bernard; Hurd, Mark W.; Shen, John Paul; Zhao, Dan Share Save
Integrated spatial transcriptomics and lipidomics analyses of intraductal papillary mucinous neoplasm identifies enrichment of long chain sulfatide as an early metabolic alteration Chen, Yihui; Sans, Marta; Thege, Fredrik; Dou, Rongzhang; Min, Jimin; Yip-Schneider, Michele; Zhang, Jianjun; Wu, Ranran; Irajizad, Ehsan; Makino, Yuki; Rajapakshe, Kimal; Hurd, Mark; Leon-Letelier, Ricardo; Vykoukal, Jody; Dennison, Jennifer; Do, Kim-Anh; Wolff, Robert; Guerrero, Paola; Kim, Michael; Schmidt, Max; Maitra, Anirban; Hanash, Samir; Fahrmann, Johannes Share Save
Transcriptomic Profiling of Plasma Extracellular Vesicles Enables Reliable Annotation of the Cancer-Specific Transcriptome and Molecular Subtype Bahrambeigi, Vahid; Lee, Jaewon J.; Branchi, Vittorio; Rajapakshe, Kimal I.; Xu, Zhichao; Kui, Naishu; Henry, Jason T.; Kun, Wang; Stephens, Bret M.; Dhebat, Sarah; Hurd, Mark W.; Sun, Ryan; Yang, Peng; Ruppin, Eytan; Wang, Wenyi; Kopetz, Scott; Maitra, Anirban; Guerrero, Paola A. Share Save
Impact of KRAS mutations and co-mutations on clinical outcomes in pancreatic ductal adenocarcinoma Yousef, Abdelrahman; Yousef, Mahmoud; Chowdhury, Saikat; Abdilleh, Kawther; Knafl, Mark; Edelkamp, Paul; Alfaro-Munoz, Kristin; Chacko, Ray; Peterson, Jennifer; Smaglo, Brandon G.; Wolff, Robert A.; Pant, Shubham; Lee, Michael S.; Willis, Jason; Overman, Michael; Doss, Sudheer; Matrisian, Lynn; Hurd, Mark W.; Snyder, Rebecca; Katz, Matthew H. G.; Wang, Huamin; Maitra, Anirban; Shen, John Paul; Zhao, Dan Share Save
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Combinations of previously reported biomarkers achieve improved sensitivity and specificity of detection of early stage pancreatic ductal adenocarcinoma Haab, Brian; Qian, Lu; Staal, Ben; Jain, Maneesh; Fahrmann, Johannes; Worthington, Christine; Prosser, Denise; Velokokhatnaya, Liudmila; Lopez, Camden; Tang, Runlong; Hurd, Mark; Natarajan, Gopalakrishnan; Kumar, Sushil; Smith, Lynette; Hanash, Samir; Batra, Surinder; Maitra, Anirban; Lokshin, Anna; Huang, Ying; Brand, Randall E.; Velokokhatnaya, Liudmila Share Save
iExplore: A phase I study of mesenchymal stem cell derived exosomes with KrasG12D siRNA for metastatic pancreas cancer patients harboring the KrasG12D mutation Smaglo, Brandon G.; LeBleu, Valerie S.; Lee, J. Jack; Maitra, Anirban; Kalluri, Raghu; Rezvani, Katy; Soto, Luisa M. Solis; Hurd, Mark; Kaur, Indreshpal; Vilchez, Mayela C. Mendt; Kirtley, Michelle L.; Shaftoe, Stacy L.; Morelli, Maria Pia; Overman, Michael J.; Zhou, Dan; Wolff, Robert A.; Tu, Janet; Willis, Jason A.; Huey, Ryan W.; Lee, Michael S.; Bhosale, Priya R.; Dworsky, Suzanne W.; Xu, Li; Pant, Shubham; Shpall, Elizabeth J. Share Save
Impact of KRAS mutations and co-mutations on clinical outcomes in pancreatic ductal adenocarcinoma Yousef, Abdelrahman; Yousef, Mahmoud; Chowdhury, Saikat; Abdilleh, Kawther; Knafl, Mark; Edelkamp, Paul; Alfaro-Munoz, Kristin; Chacko, Ray; Peterson, Jennifer; Smaglo, Brandon; Wolff, Robert; Pant, Shubham; Lee, Michael; Willis, Jason; Overman, Michael; Doss, Sudheer; Matrisian, Lynn; Hurd, Mark; Snyder, Rebecca; Katz, Matthew; Wang, Huamin; Maitra, Anirban; Shen, John Paul; Zhao, Dan Share Save
Impact of KRAS mutations and co-mutations on clinical outcomes in Pancreatic Ductal Adenocarcinoma Yousef, Abdelrahman; Yousef, Mahmoud; Chowdhury, Saikat; Abdilleh, Kawther; Knafti, Mark; Edelkamp, Paul; Alfaro-Munoz, Kristin; Chacko, Ray; Peterson, Jennifer; Smalgo, Brandon; Wolff, Robert; Pant, Shubham; Lee, Michael; Willis, Jason; Overman, Michael; Doss, Sudheer; Matrisian, Lynn; Hurd, Mark; Synder, Rebecca; Katz, Matthew Harold; Wang, Huamin; Maitra, Anirban; Shen, John Paul; Zhao, Dan Share Save
Spatial Transcriptomics of Intraductal Papillary Mucinous Neoplasms of the Pancreas Identifies NKX6-2 as a Driver of Gastric Differentiation and Indolent Biological Potential Sans, Marta; Makino, Yuki; Min, Jimin; Rajapakshe, Kimal I.; Yip-Schneider, Michele; Schmidt, C. Max; Hurd, Mark W.; Burks, Jared K.; Gomez, Javier A.; Thege, Fredrik I.; Fahrmann, Johannes F.; Wolff, Robert A.; Kim, Michael P.; Guerrero, Paola A.; Maitra, Anirban Share Save
3D imaging analysis on an organoid-based platform guides personalized treatment in pancreatic ductal adenocarcinoma Kang, Ya'an; Deng, Jenying; Ling, Jianhua; Li, Xinqun; Chiang, Yi-Ju; Koay, Eugene J.; Wang, Huamin; Burks, Jared K.; Chiao, Paul J.; Hurd, Mark W.; Bhutani, Manoop S.; Lee, Jeffrey H.; Weston, Brian R.; Maitra, Anirban; Ikoma, Naruhiko; Tzeng, Ching-Wei D.; Lee, Jeffrey E.; DePinho, Ronald A.; Wolff, Robert A.; Pant, Shubham; McAllister, Florencia; Katz, Matthew H. G.; Fleming, Jason B.; Kim, Michael P. Share Save
Single-Cell Sequencing Reveals Trajectory of Tumor-Infiltrating Lymphocyte States in Pancreatic Cancer Schalck, Aislyn; Sakellariou-Thompson, Donastas; Forget, Marie-Andree; Sei, Emi; Hughes, Tara G.; Reuben, Alexandre; Bai, Shanshan; Hu, Min; Kumar, Tapsi; Hurd, Mark W.; Katz, Matthew H. G.; Tzeng, Ching-Wei D.; Pant, Shubham; Javle, Milind; Fogelman, David R.; Maitra, Anirban; Haymaker, Cara L.; Kim, Michael P.; Navin, Nicholas E.; Bernatchez, Chantale Share Save
Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers Bradley, Sherille D.; Talukder, Amjad H.; Lai, Ivy; Davis, Rebecca; Alvarez, Hector; Tiriac, Herve; Zhang, Minying; Chiu, Yulun; Melendez, Brenda; Jackson, Kyle R.; Katailiha, Arjun; Sonnemann, Heather M.; Li, Fenge; Kang, Yaan; Qiao, Na; Pan, Bih-Fang; Lorenzi, Philip L.; Hurd, Mark; Mittendorf, Elizabeth A.; Peterson, Christine B.; Javle, Milind; Bristow, Christopher; Kim, Michael; Tuveson, David A.; Hawke, David; Kopetz, Scott; Wolff, Robert A.; Hwu, Patrick; Maitra, Anirban; Roszik, Jason; Yee, Cassian; Lizee, Gregory Share Save
Circulating Nucleic Acids Are Associated With Outcomes of Patients With Pancreatic Cancer Bernard, Vincent; Kim, Dong U.; San Lucas, F. Anthony; Castillo, Jonathan; Allenson, Kelvin; Mulu, Feven C.; Stephens, Bret M.; Huang, Jonathan; Semaan, Alexander; Guerrero, Paola A.; Kamyabi, Nabiollah; Zhao, Jun; Hurd, Mark W.; Koay, Eugene J.; Taniguchi, Cullen M.; Herman, Joseph M.; Javle, Milind; Wolff, Robert; Katz, Matthew; Varadhachary, Gauri; Maitra, Anirban; Alvarez, Hector A. Share Save
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