Not logged in Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease in lung cancer Haderk, Franziska; Chou, Yu-Ting; Cech, Lauren; Fernandez-Mendez, Celia; Yu, Johnny; Olivas, Victor; Meraz, Ismail M.; Rabago, Dora Barbosa; Kerr, D. Lucas; Gomez, Carlos; Allegakoen, David V.; Guan, Juan; Shah, Khyati N.; Herrington, Kari A.; Gbenedio, Oghenekevwe M.; Nanjo, Shigeki; Majidi, Mourad; Tamaki, Whitney; Pourmoghadam, Yashar K.; Rotow, Julia K.; McCoach, Caroline E.; Riess, Jonathan W.; Gutkind, J. Silvio; Tang, Tracy T.; Post, Leonard; Huang, Bo; Santisteban, Pilar; Goodarzi, Hani; Bandyopadhyay, Sourav; Kuo, Calvin J.; Roose, Jeroen P.; Wu, Wei; Blakely, Collin M.; Roth, Jack A.; Bivona, Trever G. Share Save
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The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance Caswell, Deborah R.; Gui, Philippe; Mayekar, Manasi K.; Law, Emily K.; Pich, Oriol; Bailey, Chris; Boumelha, Jesse; Kerr, D. Lucas; Blakely, Collin M.; Manabe, Tadashi; Martinez-Ruiz, Carlos; Bakker, Bjorn; Villcas, Juan De Dios Palomino; I. Vokes, Natalie; Dietzen, Michelle; Angelova, Mihaela; Gini, Beatrice; Tamaki, Whitney; Allegakoen, Paul; Wu, Wei; Humpton, Timothy J.; Hill, William; Tomaschko, Mona; Lu, Wei-Ting; Haderk, Franziska; Al Bakir, Maise; Nagano, Ai; Gimeno-Valiente, Francisco; Trecesson, Sophie de Carne; Vendramin, Roberto; Barbe, Vittorio; Mugabo, Miriam; Weeden, Clare E.; Rowan, Andrew; McCoach, Caroline E.; Almeida, Bruna; Green, Mary; Gomez, Carlos; Nanjo, Shigeki; Barbosa, Dora; Moore, Chris; Przewrocka, Joanna; Black, James R. M.; Gronroos, Eva; Suarez-Bonnet, Alejandro; Priestnall, Simon L.; Zverev, Caroline; Lighterness, Scott; Cormack, James; Olivas, Victor; Cech, Lauren; Andrews, Trisha; Rule, Brandon; Jiao, Yuwei; Zhang, Xinzhu; Ashford, Paul; Durfee, Cameron; Venkatesan, Subramanian; Temiz, Nuri Alpay; Tan, Lisa; Larson, Lindsay K.; Argyris, Prokopios P.; Brown, William L.; Yu, Elizabeth A.; Rotow, Julia K.; Guha, Udayan; Roper, Nitin; Yu, Johnny; Vogel, Rachel I.; Thomas, Nicholas J.; Marra, Antonio; Selenica, Pier; Yu, Helena; Bakhoum, Samuel F.; Chew, Su Kit; Reis-Filho, Jorge S.; Jamal-Hanjani, Mariam; Vousden, Karen H.; McGranahan, Nicholas; Van Allen, Eliezer M.; Kanu, Nnennaya; Harris, Reuben S.; Downward, Julian; Bivona, Trever G.; Swanton, Charles Share Save
3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib (vol 6, 509, 2023) Meraz, Ismail M.; Majidi, Mourad; Fang, Bingliang; Meng, Feng; Gao, Lihui; Shao, RuPing; Song, Renduo; Li, Feng; Lissanu, Yonathan; Chen, Huiqin; Ha, Min Jin; Wang, Qi; Wang, Jing; Shpall, Elizabeth; Jung, Sung Yun; Haderk, Franziska; Gui, Philippe; Riess, Jonathan Wesley; Olivas, Victor; Bivona, Trever G.; Roth, Jack A. Share Save
3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib Meraz, Ismail M.; Majidi, Mourad; Fang, Bingliang; Meng, Feng; Gao, Lihui; Shao, RuPing; Song, Renduo; Li, Feng; Lissanu, Yonathan; Chen, Huiqin; Ha, Min Jin; Wang, Qi; Wang, Jing; Shpall, Elizabeth; Jung, Sung Yun; Haderk, Franziska; Gui, Philippe; Riess, Jonathan Wesley; Olivas, Victor; Bivona, Trever G.; Roth, Jack A. Share Save
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Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in EGFR-mutant lung cancer Nanjo, Shigeki; Wu, Wei; Karachaliou, Niki; Blakely, Collin M.; Suzuki, Junji; Chou, Yu-Ting; Ali, Siraj M.; Kerr, D. Lucas; Olivas, Victor R.; Shue, Jonathan; Rotow, Julia; Mayekar, Manasi K.; Haderk, Franziska; Chatterjee, Nilanjana; Urisman, Anatoly; Yeo, Jia Chi; Skanderup, Anders J.; Tan, Aaron C.; Tam, Wai Leong; Arrieta, Oscar; Hosomichi, Kazuyoshi; Nishiyama, Akihiro; Yano, Seiji; Kirichok, Yuriy; Tan, Daniel S. W.; Rosell, Rafael; Okimoto, Ross A.; Bivona, Trever G. Share Save
Co-occurring Alterations in the RAS-MAPK Pathway Limit Response to MET Inhibitor Treatment in MET Exon 14 Skipping Mutation-Positive Lung Cancer Rotow, Julia K.; Gui, Philippe; Wu, Wei; Raymond, Victoria M.; Lanman, Richard B.; Kaye, Frederic J.; Peled, Nir; de la Cruz, Ferran Fece; Nadres, Brandon; Corcoran, Ryan B.; Yeh, Iwei; Bastian, Boris C.; Starostik, Petr; Newsom, Kimberly; Olivas, Victor R.; Wolff, Alexander M.; Fraser, James S.; Collisson, Eric A.; McCoach, Caroline E.; Camidge, D. Ross; Pacheco, Jose; Bazhenova, Lyudmila; Li, Tianhong; Bivona, Trever G.; Blakely, Collin M. Share Save
Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers Chatterjee, Nilanjana; Pazarentzos, Evangelos; Mayekar, Manasi K.; Gui, Philippe; Allegakoen, David V.; Hrustanovic, Gorjan; Olivas, Victor; Lin, Luping; Verschueren, Erik; Johnson, Jeffrey R.; Hofree, Matan; Yan, Jenny J.; Newton, Billy W.; Dollen, John V.; Earnshaw, Charles H.; Flanagan, Jennifer; Chan, Elton; Asthana, Saurabh; Ideker, Trey; Wu, Wei; Suzuki, Junji; Barad, Benjamin A.; Kirichok, Yuriy; Fraser, James S.; Weiss, William A.; Krogan, Nevan J.; Tulpule, Asmin; Sabnis, Amit J.; Bivona, Trever G. Share Save
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Non-genetic TPX2/AURKA signaling facilitates tumor evolution in EGFR-TKI resistance in NSCLC Shah, Khyati N.; Bhatt, Roma; Rotow, Julia; Rohrberg, Julia; Olivas, Victor; Wang, Victoria E.; Kuhn, Jonathan; Dumont, Sophie; Mccormick, Frank; Goga, Andrei; Blakely, Collin M.; Bivona, Trever G.; Bandyopadhyay, Sourav Share Save
Differential Subcellular Localization Regulates Oncogenic Signaling by ROS1 Kinase Fusion Proteins Neel, Dana S.; Allegakoen, David V.; Olivas, Victor; Mayekar, Manasi K.; Hemmati, Golzar; Chatterjee, Nilanjana; Blakely, Collin M.; McCoach, Caroline E.; Rotow, Julia K.; Le, Anh; Karachaliou, Niki; Rosell, Rafael; Riess, Jonathan W.; Nichols, Robert; Doebele, Robert C.; Bivona, Trever G. Share Save
Use of nonsteroidal anti-inflammatory drugs predicts improved patient survival for PIK3CA-altered head and neck cancer Hedberg, Matthew L.; Peyser, Noah D.; Bauman, Julie E.; Gooding, William E.; Li, Hua; Bhola, Neil E.; Zhu, Tian Ran; Zeng, Yan; Brand, Toni M.; Kim, Mi-Ok; Jordan, Richard C. K.; VandenBerg, Scott; Olivas, Victor; Bivona, Trever G.; Chiosea, Simion I.; Wang, Lin; Mills, Gordon B.; Johnson, Jonas T.; Duvvuri, Umamaheswar; Ferris, Robert L.; Ha, Patrick; Johnson, Daniel E.; Grandis, Jennifer R. Share Save
Aurora kinase A drives the evolution of resistance to third-generation EGFR inhibitors in lung cancer Shah, Khyati N.; Bhatt, Roma; Rotow, Julia; Rohrberg, Julia; Olivas, Victor; Wang, Victoria E.; Hemmati, Golzar; Martins, Maria M.; Maynard, Ashley; Kuhn, Jonathan; Galeas, Jacqueline; Donnella, Hayley J.; Kaushik, Swati; Ku, Angel; Dumont, Sophie; Krings, Gregor; Haringsma, Henry J.; Robillard, Liliane; Simmons, Andrew D.; Harding, Thomas C.; McCormick, Frank; Goga, Andrei; Blakely, Collin M.; Bivona, Trever G.; Bandyopadhyay, Sourav Share Save
RAS nucleotide cycling underlies the SHP2 phosphatase dependence of mutant BRAF-, NF1-and RAS-driven cancers Nichols, Robert J.; Haderk, Franziska; Stahlhut, Carlos; Schulze, Christopher J.; Hemmati, Golzar; Wildes, David; Tzitzilonis, Christos; Mordec, Kasia; Marquez, Abby; Romero, Jason; Hsieh, Tientien; Zaman, Aubhishek; Olivas, Victor; McCoach, Caroline; Blakely, Collin M.; Wang, Zhengping; Kiss, Gert; Koltun, Elena S.; Gill, Adrian L.; Singh, Mallika; Goldsmith, Mark A.; Smith, Jacqueline A. M.; Bivona, Trever G. Share Save
Aurora kinase A drives the evolution of resistance to third-generation EGFR inhibitors in lung cancer Shah, Khyati N.; Bhatt, Roma; Rotow, Julia; Rohrberg, Julia; Olivas, Victor; Hemmati, Golzar Golzar; Krings, Gregor; Haringsma, Henry J.; Simmons, Andrew D.; Harding, Thomas C.; Goga, Andrei; Blakely, Collin; Bivona, Trever; Bandyopadhyay, Sourav Share Save
TNF-driven adaptive response mediates resistance to EGFR inhibition in lung cancer Gong, Ke; Guo, Gao; Gerber, David E.; Gao, Boning; Peyton, Michael; Huang, Chun; Minna, John D.; Hatanpaa, Kimmo J.; Kernstine, Kemp; Cai, Ling; Xie, Yang; Zhu, Hong; Fattah, Farjana J.; Zhang, Shanrong; Takahashi, Masaya; Mukherjee, Bipasha; Burma, Sandeep; Dowell, Jonathan; Dao, Kathryn; Papadimitrakopoulou, Vassiliki A.; Olivas, Victor; Bivona, Trever G.; Zhao, Dawen; Habib, Amyn A. Share Save
Imaging PD-L1 Expression with ImmunoPET Truillet, Charles; Oh, Hsueh Ling J.; Yeo, Siok Ping; Lee, Chia-Yin; Huynh, Loc T.; Wei, Junnian; Parker, Matthew F. L.; Blakely, Collin; Sevillano, Natalia; Wang, Yun-Hua; Shen, Yuqin S.; Olivas, Victor; Jami, Khaled. M.; Moroz, Anna; Jego, Benoit; Jaumain, Emilie; Fong, Lawrence; Craik, Charles S.; Chang, Albert J.; Bivona, Trever G.; Wang, Cheng-I; Evans, Michael J. Share Save
Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers Blakely, Collin M.; Watkins, Thomas B. K.; Wu, Wei; Gini, Beatrice; Chabon, Jacob J.; McCoach, Caroline E.; McGranahan, Nicholas; Wilson, Gareth A.; Birkbak, Nicolai J.; Olivas, Victor R.; Rotow, Julia; Maynard, Ashley; Wang, Victoria; Gubens, Matthew A.; Banks, Kimberly C.; Lanman, Richard B.; Caulin, Aleah F.; St John, John; Cordero, Anibal R.; Giannikopoulos, Petros; Simmons, Andrew D.; Mack, Philip C.; Gandara, David R.; Husain, Hatim; Doebele, Robert C.; Riess, Jonathan W.; Diehn, Maximilian; Swanton, Charles; Bivona, Trever G. Share Save
Chronic NSAID use increases survival in PIK3CA-altered head and neck squamous cell carcinoma Hedberg, Matthew Louis; Peyser, Noah; Gooding, William; Li, Hua; Brand, Toni; Olivas, Victor; Bivona, Trever; Choisea, Simion; Wang, Lin; Johnson, Jonas; Duvvuri, Uma; Ferris, Robert; Johnson, Daniel; Ha, Patrick; Bauman, Julie; Grandis, Jennifer Share Save
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