Not logged inELECTROCORTICOGRAPHIC ANALYSIS AND DETECTION OF SPEECH NETWORKS IN GLIOMA-INFILTRATED CORTEX
Ambati, Vardhaan; Persad, Amit; Kaur, Jasleen; Herr, Sanjeev; Cunningham, Emily; Dada, Abraham; Ekhart, Justyna; Greicius, Quinn; Silva, Alex; Villalobos, Paul; Olshausen, Niels; Sibih, Youssef; Oten, Sena; Yamada, Hunter; Umbach, Gray; Aabedi, Alexander; Al-Holou, Wajd; Young, Jacob; Sushil, Madhumita; Chang, Edward; Berger, Mitchel; Brang, David; Hervey-Jumper, Shawn .png)
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SaveEnhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant MelanomaMaitituoheti, Mayinuer; Keung, Emily Z.; Tang, Ming; Yan, Liang; Alam, Hunain; Han, Guangchun; Singh, Anand K.; Raman, Ayush T.; Terranova, Christopher; Sarkar, Sharmistha; Orouji, Elias; Amin, Samir B.; Sharma, Sneha; Williams, Maura; Samant, Neha S.; Dhamdhere, Mayura; Zheng, Norman; Shah, Tara; Shah, Amiksha; Axelrad, Jacob B.; Anvar, Nazanin E.; Lin, Yu-Hsi; Jiang, Shan; Chang, Edward Q.; Ingram, Davis R.; Wang, Wei-Lien; Lazar, Alexander; Lee, Min Gyu; Muller, Florian; Wang, Linghua; Ying, Haoqiang; Rai, Kunal Share Save Discovery of IACS-9439, a Potent, Exquisitely Selective, and Orally Bioavailable Inhibitor of CSF1RCzako, Barbara; Marszalek, Joseph. R.; Burke, Jason P.; Mandal, Pijus; Leonard, Paul G.; Cross, Jason B.; Mseeh, Faika; Jiang, Yongying; Chang, Edward Q.; Suzuki, Erika; Kovacs, Jeffrey J.; Feng, Ningping; Gera, Sonal; Harris, Angela L.; Liu, Zhen; Mullinax, Robert A.; Pang, Jihai; Parker, Connor A.; Spencer, Nakia D.; Yu, Simon S.; Wu, Qi; Tremblay, Martin R.; Mikule, Keith; Wilcoxen, Keith; Heffernan, Timothy P.; Draetta, Giulio F.; Jones, Philip Share Save Targeting OXPHOS with IACS-010759 to eliminate standard of care resistant tumor cellsMarszalek, Joseph R.; Seth, Sahil; Corti, Denise; Zhang, Qi; Echeverria, Gloria V.; Han, Lina; Sun, Yuting; Molina, Jennifer; Gera, Sonal; Chang, Edward; Khor, Tin O.; Mahendra, Mikhila; Feng, Ningping; Gay, Jason P.; McAfoos, Timothy; Giuliani, Virginia; Shi, Xi; Jeter-Jones, Sabrina; Loponte, Sarah; Li, Chieh-Yuan; Bristow, Christopher A.; Di Francesco, Maria Emilia; Piwnica-Worms, Helen; Konopleva, Marina; Carugo, Alessandro; Viale, Andrea; Jones, Philip; Heffernan, Timothy P.; Draetta, Giulio F. Share Save An inhibitor of oxidative phosphorylation exploits cancer vulnerabilityMolina, Jennifer R.; Sun, Yuting; Protopopova, Marina; Gera, Sonal; Bandi, Madhavi; Bristow, Christopher; McAfoos, Timothy; Morlacchi, Pietro; Ackroyd, Jeffrey; Agip, Ahmed-Noor A.; Al-Atrash, Gheath; Asara, John; Bardenhagen, Jennifer; Carrillo, Caroline C.; Carroll, Christopher; Chang, Edward; Ciurea, Stefan; Cross, Jason B.; Czako, Barbara; Deem, Angela; Daver, Naval; de Groot, John Frederick; Dong, Jian-Wen; Feng, Ningping; Gao, Guang; Gay, Jason; Do, Mary Geck; Greer, Jennifer; Giuliani, Virginia; Han, Jing; Han, Lina; Henry, Verlene K.; Hirst, Judy; Huang, Sha; Jiang, Yongying; Kang, Zhijun; Khor, Tin; Konoplev, Sergej; Lin, Yu-Hsi; Liu, Gang; Lodi, Alessia; Lofton, Timothy; Ma, Helen; Mahendra, Mikhila; Matre, Polina; Mullinax, Robert; Peoples, Michael; Petrocchi, Alessia; Rodriguez-Canale, Jaime; Serreli, Riccardo; Shi, Thomas; Smith, Melinda; Tabe, Yoko; Theroff, Jay; Tiziani, Stefano; Xu, Quanyun; Zhang, Qi; Muller, Florian; DePinho, Ronald A.; Toniatti, Carlo; Draetta, Giulio F.; Heffernan, Timothy P.; Konopleva, Marina; Jones, Philip; Di Francesco, M. Emilia; Marszalek, Joseph R. Share Save Identification of protein arginine methyltransferase 1 as novel epigenetic vulnerability in KRAS/p53 mutant PDAC primary patient modelsGiuliani, Virginia; Vangamudi, Bhavatarini; Suzuki, Erika; Miller, Meredith; Liu, Chiu-Yi; Carugo, Alessandro; Bristow, Christopher; Gao, Guang; Han, Jing; Sun, Yuting; Feng, Ningping; Chang, Edward; Marszalek, Joseph; Kovacs, Jeffrey; Di Francesco, Maria Emilia; Toniatti, Carlo; Heffernan, Timothy; Jones, Philip; Draetta, Giulio Share Save IACS-010759, a novel inhibitor of complex I in Phase I clinical development to target OXPHOS dependent tumorsMolina, Jennifer; Bandi, Madhavi; Bardenhagen, Jennifer; Bristow, Christopher; Carroll, Christopher; Chang, Edward; Cross, Jason; Daver, Naval; Feng, Ningping; Gay, Jason; Do, Mary Geck; Greer, Jennifer; Han, Jing; Hirst, Judy; Huang, Sha; Jiang, Yongying; Kang, Zhijun; Konopleva, Marina; Liu, Gang; Ma, Helen; Matre, Polina; McAfoos, Timothy; Meric-Bernstam, Funda; Morlacchi, Pietro; Muller, Florian; Protopopova, Marina; Smith, Melinda; Sonal, Sonal; Sun, Yuting; Theroff, Jay; Viale, Andrea; Xu, Quanyun; Toniatti, Carlo; Draetta, Giulio; Jones, Philip; Di Francesco, M. Emilia; Marszalek, Joseph R. Share Save Title: IACS-010759 is a novel clinical candidate that targets AML cells by inducing a metabolic catastrophe through inhibition of oxidative phosphorylationMolina, Jennifer R.; Protopopova, Marina; Bandi, Madhavi; Bardenhagen, Jennifer; Bristow, Christopher; Carroll, Christopher; Chang, Edward; Feng, Ningping; Gay, Jason; Do, Mary Geck; Greer, Jennifer; Huang, Sha; Jiang, Yongying; Konopleva, Marina; Matre, Polina; Han, Jing; Kang, Zhijun; Liu, Gang; McAfoos, Timothy; Morlacchi, Pietro; Smith, Melinda; Gera, Sonal; Theroff, Jay; Xu, Quanyun; Velez, Juliana; Toniatti, Carlo; Heffernan, Timothy; Draetta, Giulio; Di Francesco, M. Emilia; Jones, Philip; Marszalek, Joseph R. Share Save LKB1 loss is associated with resistance to VEGF inhibitors in non-small cell lung cancer (NSCLC)Guijarro, Irene; Poteete, Alissa; Yang, Chao; Roarty, Emily; Nilsson, Monique; Sun, Huiying; Tong, Pan; Chang, Edward; Rodriguez-Canales, Jaime; Mino, Barbara; Parra, Edwin; Wistuba, Ignacio; Wang, Jing; Heffernan, Timothy; Heymach, John V. Share Save IACS-10759: A novel OXPHOS inhibitor that selectively kills tumors with metabolic vulnerabilitiesProtopopova, Marina; Bandi, Madhavi; Sun, Yuting; Bardenhagen, Jennifer; Bristow, Christopher; Carroll, Christopher; Chang, Edward; Feng, Ningping; Gay, Jason; Do, Mary Geck; Greer, Jennifer; Konopleva, Marina; Matre, Polina; Kang, Zhijun; Liu, Gang; Muller, Florian; Lofton, Timothy; McAfoos, Timothy; Smith, Melinda; Theroff, Jay; Han, Jing; Wu, Yuanqing; Chin, Lynda; Draetta, Giulio; Jones, Philip; Toniatti, Carlo; Di Francesco, M. Emilia; Marszalek, Joseph R. Share Save Relapsed/refractory AML responds robustly to IACS-10759, a novel OXPHOS inhibitorProtopopova, Marina; Bandi, Madhavi; Bardenhagen, Jennifer; Bristow, Christophor; Carroll, Christopher; Chang, Edward; Feng, Ningping; Gay, Jason; Do, Mary Geck; Greer, Jennifer; Konopleva, Marina; Matre, Polina; Kang, Zhijun; Liu, Gang; Muller, Florian; Lofton, Timothy; McAfoos, Timothy; Theroff, Jay; Sun, Yuting; Wu, Yuanqiang; Smith, Melinda; Chin, Lynda; Draetta, Giulio; Jones, Philip; Toniatti, Carlo; Di Francesco, M. Emilia; Marszalek, Joseph R. Share Save IACS-10759: A novel OXPHOS inhibitor which selectively kill tumors with metabolic vulnerabilitiesProtopopova, Marina; Bandi, Madhavi; Bardenhagen, Jennifer; Bristow, Christopher; Carroll, Christopher; Chang, Edward; Feng, Ningping; Gay, Jason; Do, Mary Geck; Greer, Jennifer; Konopleva, Marina; Matre, Polina; Kang, Zhijun; Liu, Gang; Muller, Florian; Lofton, Timothy; McAfoos, Timothy; Sun, Yuting; Smith, Melinda; Theroff, Jay; Wu, Yuanqiang; Chin, Lynda; Draetta, Giulio; Jones, Philip; Toniatti, Carlo; Di Francesco, M. Emilia; Marszalek, Joseph R. Share Save Identification of OXPHOS inhibitors which selectively kill tumors with specific metabolic vulnerabilitiesMarszalek, Joseph R.; Bandi, Madhavi; Bardenhagen, Jennifer; Bristow, Christopher; Carroll, Christopher; Chang, Edward; Feng, Ninping; Czako, Barbara; Gay, Jason; Do, Mary Geck; Greer, Jennifer; Johnson, Ryan M.; Konopleva, Marina; Kang, Zhijun; Liu, Gang; Lofton, Timothy; McAfoos, Timothy; Protopopova, Marina; Petrocchi, Alessia; Muller, Florian; Theroff, Jay; Wu, Yuanqing; Chin, Lynda; Draetta, Giulio; Jones, Philip; Toniatti, Carlo; Di Francesco, Emilia Share Save Applying TCGA data for breast cancer diagnostics and pathway analysisAndersen, Jannik; Shah, Parantu; Korski, Konstanty; Ibbs, Matthew; Filas, Violetta; Kosiedowski, Michal; Pukacki, Juliusz; Mazurek, Cezary; Wu, Yuanqing; Chang, Edward; Toniatti, Carlo; Draetta, Giulio; Wiznerowicz, Maciej Share Save ARQ 087, a multi-tyrosine kinase inhibitor with potent in vitro and in vivo activity in FGFR2 driven models.Dransfield, Daniel; Lee, Jennifer; Waghorne, Carol; Bull, Cathy; Savage, Ronald E.; Zhao, Xiaolan; Yuan, Shipeng; Chang, Edward; Nakuci, Enkeleda; Eathiraj, Sudharshan; Cornell-Kennon, Susan; Gu, Xiubin; Ali, Syed; Chen, Chang-Rung Share Save Exploratory biomarker discovery for clinical development of ARQ 087, a potent pan-FGFR kinase inhibitorYu, Yi; Gu, Xiubin; Nakuci, Enkelada; Zhao, Xiaolan; Chang, Edward; Szwaya, Jeff; Castro, Jenn; Cousens, Laura; Bull, Cathy; Wang, Yunxia; Savage, Ron; Waghorne, Carol; Chen, Chang-Rung; France, Dennis S.; Clark, Edwin; Chan, Thomas C. K. Share Save Share Save Share Save Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and AngiogenesisDevy, Laetitia; Huang, Lili; Naa, Laurent; Yanamandra, Niranjan; Pieters, Henk; Frans, Nicolas; Chang, Edward; Tao, Qingfeng; Vanhove, Marc; Lejeune, Annabelle; van Gool, Reinoud; Sexton, Daniel J.; Kuang, Guannan; Rank, Douglas; Hogan, Shannon; Pazmany, Csaba; Ma, Yu Lu; Schoonbroodt, Sonia; Nixon, Andrew E.; Ladner, Robert C.; Hoet, Rene; Henderikx, Paula; TenHoor, Chris; Rabbani, Shafaat A.; Valentino, Maria Luisa; Wood, Clive R.; Dransfield, Daniel T. Share Save 
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