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Paulo J.C. Lin

acuitas therapeutics, vancouver, bc v6t 1z3, canada.

36H-index
141Paper Count
6.6KCitation Count
Published Papers 45
Publication Date
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Computationally designed mRNA-launched protein nanoparticle immunogens elicit protective antibody and T cell responses in mice
errScience Translational Medicine
IF14.6
err2025-10-15
err0
PREAI
errGrace G. Hendricks; Lilit Grigoryan; Mary Jane Navarro; Nicholas J. Catanzaro; Miranda L. Hubbard; John M. Powers; Melissa Mattocks; Catherine Treichel; Alexandra C. Walls; Jimin Lee; Daniel Ellis; Jing Yang (John) Wang; Suna Cheng; Marcos C. Miranda; Adian Valdez; Cara W. Chao; Sidney Chan; Christine Men; Max R. Johnson; Samantha K. Zepeda; Sebastian Ols; Harold Hui; Sheng-Yang Wu; Victor Lujan; Hiromi Muramatsu; Paulo J.C. Lin; Molly M.H. Sung; Ying K. Tam; Elizabeth M. Leaf; Norbert Pardi; Ralph S. Baric; Bali Pulendran; David Veesler; Alexandra Schäfer; Neil P. King
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errSave
Treatment of a metabolic liver disease in mice with a transient prime editing approach
errNATURE BIOMEDICAL ENGINEERING
IF26.6
err2025-05-20
err0
errOAAI
errRothgangl, Tanja; Talas, Andras; Ioannidi, Eleonora I.; Weber, Yanik; Bock, Desiree; Matsushita, Mai; Villiger, Elina Andrea; Schmidheini, Lukas; Moon, Woohyun J.; Lin, Paulo J. C.; Fan, Steven H. Y.; Marquart, Kim F.; Schwerdel, Cornelia; Rimann, Nicole; Faccin, Erica; Villiger, Lukas; Muramatsu, Hiromi; Vadovics, Mate; Cremonesi, Alessio; Kulcsar, Peter Istvan; Thoeny, Beat; Kopf, Manfred; Haberle, Johannes; Pardi, Norbert; Tam, Ying K.; Schwank, Gerald
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errSave
Predicting adenine base editing efficiencies in different cellular contexts by deep learning
errGENOME BIOLOGY
IF9.4
err2025-05-08
err0
errOAAI
errKissling, Lucas; Mollaysa, Amina; Janjuha, Sharan; Mathis, Nicolas; Marquart, Kim F.; Weber, Yanik; Moon, Woohyun J.; Lin, Paulo J. C.; Fan, Steven H. Y.; Muramatsu, Hiromi; Vadovics, Mate; Allam, Ahmed; Pardi, Norbert; Tam, Ying K.; Krauthammer, Michael; Schwank, Gerald
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errSave
Lipid nanoparticles (LNP) induce activation and maturation of antigen presenting cells in young and aged individuals (vol 6, 188, 2023)
errCOMMUNICATIONS BIOLOGY
IF5.1
err2025-02-22
err0
errOAAI
errConnors, Jennifer; Joyner, David; Mege, Nathan J.; Cusimano, Gina M.; Bell, Matthew R.; Marcy, Jennifer; Taramangalam, Bhavani; Kim, Kenneth M.; Lin, Paulo J. C.; Tam, Ying K.; Weissman, Drew; Kutzler, Michele A.; Alameh, Mohamad-Gabriel; Haddad, Elias K.
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errSave
mRNA lipid nanoparticles expressing cell-surface cleavage independent HIV Env trimers elicit autologous tier-2 neutralizing antibodies
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-07-25
err1
errOAAI
errGuenaga, Javier; Alirezaei, Mehrdad; Feng, Yu; Alameh, Mohamad-Gabriel; Lee, Wen-Hsin; Baboo, Sabyasachi; Cluff, Jocelyn; Wilson, Richard; Bale, Shridhar; Ozorowski, Gabriel; Lin, Paulo; Tam, Ying; Diedrich, Jolene K.; Yates III, John R.; Paulson, James C.; Ward, Andrew B.; Weissman, Drew; Wyatt, Richard T.
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errSave
Exploring Mechanisms of Lipid Nanoparticle-Mucus Interactions in Healthy and Cystic Fibrosis Conditions
errADVANCED HEALTHCARE MATERIALS
IF9.6
err2024-04-13
err3
errOAAI
errTafech, Belal; Rokhforouz, Mohammad-Reza; Leung, Jerry; Sung, Molly M. H.; Lin, Paulo J. C.; Sin, Don D.; Lauster, Daniel; Block, Stephan; Quon, Bradley S.; Tam, Ying; Cullis, Pieter; Feng, James J.; Hedtrich, Sarah
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errSave
Multivalent cytomegalovirus glycoprotein B nucleoside modified mRNA vaccines did not demonstrate a greater antibody breadth
errNPJ VACCINES
IF6.5
err2024-02-20
err4
errOAAI
errWang, Hsuan-Yuan; Li, Leike; Nelson, Cody S.; Barfield, Richard; Valencia, Sarah; Chan, Cliburn; Muramatsu, Hiromi; Lin, Paulo J. C.; Pardi, Norbert; An, Zhiqiang; Weissman, Drew; Permar, Sallie R.
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errSave
A Pvs25 mRNA vaccine induces complete and durable transmission-blocking immunity to Plasmodium vivax (vol 8, 187, 2023)
errNPJ VACCINES
IF6.5
err2024-02-19
err0
errOAAI
errKunkeaw, Nawapol; Nguitragool, Wang; Takashima, Eizo; Kangwanrangsan, Niwat; Muramatsu, Hiromi; Tachibana, Mayumi; Ishino, Tomoko; Lin, Paulo J. C.; Tam, Ying K.; Pichyangkul, Sathit; Tsuboi, Takafumi; Pardi, Norbert; Sattabongkot, Jetsumon
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errSave
Immunotherapeutic effects of specific and nonspecific mRNA-lipid nanoparticles in a mouse model of HDM-induced airway inflammation
errALLERGY
IF12
err2024-02-08
err1
errOAAI
errThanasarnthungcharoen, Chanatip; Chanasit, Supapich; Fievez, Laurence; Kaewamatawong, Theerayuth; Patniboon, Piyachat; Lin, Paulo J. C.; Bureau, Fabrice; Jacquet, Alain
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errSave
A Pvs25 mRNA vaccine induces complete and durable transmission-blocking immunity to Plasmodium vivax
errNPJ VACCINES
IF6.5
err2023-12-14
err11
errOAAI
errKunkeaw, Nawapol; Nguitragool, Wang; Takashima, Eizo; Kangwanrangsan, Niwat; Muramatsu, Hiromi; Tachibana, Mayumi; Ishino, Tomoko; Lin, Paulo J. C.; Tam, Ying K.; Pichyangkul, Sathit; Tsuboi, Takafumi; Pardi, Norbert; Sattabongkot, Jetsumon
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errSave
The Regulation of Nucleic Acid Vaccine Responses by the Microbiome
errJOURNAL OF IMMUNOLOGY
IF3.4
err2023-10-18
err2
errOAAI
errJohnson, Andrew M. F.; Hager, Kevin; Alameh, Mohamad-Gabriel; Phuong Van; Potchen, Nicole; Mayer-Blackwell, Koshlan; Fiore-Gartland, Andrew; Minot, Samuel; Lin, Paulo J. C.; Tam, Ying K.; Weissman, Drew; Kublin, James G.
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errSave
mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum (vol 7, 155, 2022)
errNPJ VACCINES
IF6.5
err2023-08-11
err0
errOAAI
errHayashi, Clifford T. H.; Cao, Yi; Clark, Leor C. C.; Tripathi, Abhai K. K.; Zavala, Fidel; Dwivedi, Garima; Knox, James; Alameh, Mohamad-Gabriel; Lin, Paulo J. C.; Tam, Ying K. K.; Weissman, Drew; Kumar, Nirbhay
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errSave
A pan-variant mRNA-LNP T cell vaccine protects HLA transgenic mice from mortality after infection with SARS-CoV-2 Beta
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2023-03-09
err5
errOAAI
errCarter, Brandon; Huang, Pinghan; Liu, Ge; Liang, Yuejin; Lin, Paulo J. C.; Peng, Bi-Hung; McKay, Lindsay G. A.; Dimitrakakis, Alexander; Hsu, Jason; Tat, Vivian; Saenkham-Huntsinger, Panatda; Chen, Jinjin; Kaseke, Clarety; Gaiha, Gaurav D.; Xu, Qiaobing; Griffiths, Anthony; Tam, Ying K.; Tseng, Chien-Te K.; Gifford, David K.
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errSave
Single immunizations of self-amplifying or non-replicating mRNA-LNP vaccines control HPV-associated tumors in mice
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2023-03-08
err47
errOAAI
errda Silva, Jamile Ramos; Rodrigues, Karine Bitencourt; Pelegrin, Guilherme Formoso; Sales, Natiely Silva; Muramatsu, Hiromi; Silva, Mariangela de Oliveira; Porchia, Bruna F. M. M.; Moreno, Ana Carolina Ramos; Aps, Luana Raposo M. M.; Venceslau-Carvalho, Alexia Adrianne; Tombacz, Istvan; Fotoran, Wesley Luzetti; Kariko, Katalin; Lin, Paulo J. C.; Tam, Ying K.; Diniz, Mariana de Oliveira; Pardi, Norbert; Ferreira, Luis Carlos de Souza
errShare
errSave
Lipid nanoparticles (LNP) induce activation and maturation of antigen presenting cells in young and aged individuals
errCOMMUNICATIONS BIOLOGY
IF5.1
err2023-02-17
err47
errOAAI
errConnors, Jennifer; Joyner, David; Mege, Nathan J. J.; Cusimano, Gina M. M.; Bell, Matthew R. R.; Marcy, Jennifer; Taramangalam, Bhavani; Kim, Kenneth M. M.; Lin, Paulo J. C.; Tam, Ying K. K.; Weissman, Drew; Kutzler, Michele A. A.; Alameh, Mohamad-Gabriel; Haddad, Elias K. K.
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errSave
Restoration of Motor Function through Delayed Intraspinal Delivery of Human IL-10-Encoding Nucleoside-Modified mRNA after Spinal Cord Injury
errRESEARCH
IF10.7
err2023-01-01
err9
errOAAI
errGal, Laszlo; Bellak, Tamas; Marton, Annamaria; Fekecs, Zoltan; Weissman, Drew; Torok, Denes; Biju, Rachana; Vizler, Csaba; Kristof, Rebeka; Beattie, Mitchell B.; Lin, Paulo J. C.; Pardi, Norbert; Nogradi, Antal; Pajer, Krisztian
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errSave
A universal influenza mRNA vaccine candidate boosts T cell responses and reduces zoonotic influenza virus disease in ferrets
errSCIENCE ADVANCES
IF12.5
err2022-12-16
err24
errOAAI
errvan de Ven, Koen; Lanfermeijer, Josien; van Dijken, Harry; Muramatsu, Hiromi; de Melo, Caroline Vilas Boas; Lenz, Stefanie; Peters, Florence; Beattie, Mitchell B.; Lin, Paulo J. C.; Ferreira, Jose A.; van den Brand, Judith; van Baarle, Debbie; Pardi, Norbert; de Jonge, Jorgen
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errSave
Exploring in vitro expression and immune potency in mice using mRNA encoding the Plasmodium falciparum malaria antigen, CelTOS
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2022-12-15
err8
errOAAI
errWaghela, Ishita N. N.; Mallory, Katherine L. L.; Taylor, Justin A. A.; Schneider, Cosette G. G.; Savransky, Tatyana; Janse, Chris J. J.; Lin, Paulo J. C.; Tam, Ying K. K.; Weissman, Drew; Angov, Evelina
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errSave
mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum
errNPJ VACCINES
IF6.5
err2022-12-01
err29
errOAAI
errHayashi, Clifford T. H.; Cao, Yi; Clark, Leor C. C.; Tripathi, Abhai K. K.; Zavala, Fidel; Dwivedi, Garima; Knox, James; Alameh, Mohamad-Gabriel; Lin, Paulo J. C.; Tam, Ying K. K.; Weissman, Drew; Kumar, Nirbhay
errShare
errSave
SARS-CoV-2 mRNA-based vaccines in the Aicardi Goutieres Syndrome
errMOLECULAR GENETICS AND METABOLISM
IF3.5
err2022-12-01
err1
errOAAI
errTakanohashi, Asako; Alameh, Mohamad-Gabriel; Woidill, Sarah; Hacker, Julia; Davis, Benjamin; Helman, Guy; Gavazzi, Francesco; Adang, Laura; D'Aiello, Russell; Winters, Patrick; Cordova, Devon; Khandaker, Taibeen; Ni, Houping; Tam, Ying; Lin, Paulo; Weissman, Drew; Shults, Justine; Vanderver, Adeline
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
J
John R. Yates
H-index: 188 · Papers: 1.5K
C
Charles M. Rice
H-index: 166 · Papers: 718
R
Ralph S. Baric
H-index: 147 · Papers: 1.1K
B
Barton F. Haynes
H-index: 144 · Papers: 834
J
James C. Paulson
H-index: 135 · Papers: 556
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