Not logged inDiscovery of long-acting APOC3 siRNA for treating patients with hypertriglyceridemia
Prakash, Thazha P.; Mullick, Adam E.; Riney, Stan; Yu, Jinghua; Nikan, Mehran; Quirk, Clare; Crutchfield, Amanda; Damle, Sagar S.; Klein, Stephanie; Swayze, Eric E. .png)
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SaveAn oral antisense oligonucleotide for PCSK9 inhibitionGennemark, Peter; Walter, Katrin; Clemmensen, Niclas; Rekic, Dinko; Nilsson, Catarina A. M.; Knochel, Jane; Holtta, Mikko; Wernevik, Linda; Rosengren, Birgitta; Kakol-Palm, Dorota; Wang, Yanfeng; Yu, Rosie Z.; Geary, Richard S.; Riney, Stan J.; Monia, Brett P.; Isaksson, Rikard; Jansson-Lofmark, Rasmus; Rocha, Cristina S. J.; Linden, Daniel; Hurt-Camejo, Eva; Crooke, Rosanne; Tillman, Lloyd; Ryden-Bergsten, Tina; Carlsson, Bjorn; Andersson, Ulf; Elebring, Marie; Tivesten, Anna; Davies, Nigel Share Save Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic indexShen, Wen; De Hoyos, Cheryl L.; Migawa, Michael T.; Vickers, Timothy A.; Sun, Hong; Low, Audrey; Bell, Thomas A., III; Rahdar, Meghdad; Mukhopadhyay, Swagatam; Hart, Christopher E.; Bell, Melanie; Riney, Stan; Murray, Susan F.; Greenlee, Sarah; Crooke, Rosanne M.; Liang, Xue-hai; Seth, Punit P.; Crooke, Stanley T. Share Save Antisense oligonucleotides targeting translation inhibitory elements in 5′ UTRs can selectively increase protein levelsLiang, Xue-hai; Sun, Hong; Shen, Wen; Wang, Shiyu; Yao, Joyee; Migawa, Michael T.; Huynh-Hoa Bui; Damle, Sagar S.; Riney, Stan; Graham, Mark J.; Crooke, Rosanne M.; Crooke, Stanley T. Share Save Disposition and Pharmacology of a GalNAc3-conjugated ASO Targeting Human Lipoprotein (a) in MiceYu, Rosie Z.; Graham, Mark J.; Post, Noah; Riney, Stan; Zanardi, Thomas; Hall, Shannon; Burkey, Jennifer; Shemesh, Colby S.; Prakash, Thazha P.; Seth, Punit P.; Swayze, Eric E.; Geary, Richard S.; Wang, Yanfeng; Henry, Scott Share Save Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in micePrakash, Thazha P.; Graham, Mark J.; Yu, Jinghua; Carty, Rick; Low, Audrey; Chappell, Alfred; Schmidt, Karsten; Zhao, Chenguang; Aghajan, Mariam; Murray, Heather F.; Riney, Stan; Booten, Sheri L.; Murray, Susan F.; Gaus, Hans; Crosby, Jeff; Lima, Walt F.; Guo, Shuling; Monia, Brett P.; Swayze, Eric E.; Seth, Punit P. Share Save 
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