Not logged in Bitopic inhibitors of mTORC1 cooperate with inhibitors of mitogen-activated protein kinase kinase to drive cytotoxicity in glioblastoma Fan, Qiwen; Koach, Jessica; Luo, Karen; Clark, Sydney; Reddy, Shruthi; Ozawa, Tomoko; Wang, Linyu; Yoda, Hiroyuki; Sale, Matthew; Mccormick, Frank; Raleigh, David R.; Gustafson, William C.; Meyerowitz, Justin; Singh, Mallika; Berger, Mitchel; Shokat, Kevan M.; Weiss, William A. Share Save
Novel Dyrk1a inhibitors impair glioblastoma proliferation and enhance the effectiveness of other cell-cycle-directed therapies Chuntova, Polly; Srivastava, Ayush; Barillas, Ashlie; Oztuk, Muhammet M.; Trivanovic, Mark; Valenzuela, Edward; Macakiage, Georgina; Yang, Rachelle S.; Hoonsbeen, Sophia; Beccari, Sol; Ozawa, Tomoko; Meijer, Laurent; Shokat, Kevan M.; Schwer, Bjoern; Young, Jacob S. Share Save
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IL6 UNDERLIES MICROENVIRONMENT IMMUNOSUPPRESSION AND RESISTANCE TO THERAPY IN GLIOBLASTOMA Young, J. S.; Cho, N.; Lucas, C. G.; Seo, K.; Najem, H.; Mirchia, K.; Chen, W. C.; Zakimi, N.; Daggubati, V; Casey-Clyde, T.; Nguyen, M. P.; Chen, A.; Phillips, J. J.; Ozawa, T.; Aghi, M. K.; Taylor, J. W.; DeRisi, J. L.; Bhaduri, A.; Heimberger, A.; Berger, M. S.; Butowski, N.; Spitzer, M. H.; Raleigh, D. R. Share Save
DNA MUTATION SEQUENCING AND METHYLATION ANALYSIS OF SOMATICNF1 MUTANT IDH-WILDTYPE GLIOBLASTOMA IDENTIFIES THREE EPIGENETIC GROUPS ANDCDKN2A/B LOSS AS A NEGATIVE PROGNOSTIC BIOMARKER Mirchia, Kanish; Pan, Sixuan; Payne, Emily; Liu, John; Peeran, Zain; Shukla, Poojan; Young, Jacob; Gupta, Rohit; Wu, Jasper; Pak, Joanna; Seo, Kyounghee; Ozawa, Tomoko; Na, Brian; Reddy, Alyssa; Braunstein, Steve; Phillips, Joanna; Chang, Susan; Solomon, David; Perry, Arie; Raleigh, David; Berger, Mitchel; Abate, Adam; Vasudevan, Harish Share Save
EPIGENETIC EDITING BY MRNA-BASED CRISPROFF ENABLES FLEXIBLE AND DURABLE TARGETING OF GLIOBLASTOMA DRIVERS MGMT AND TERT Lin, Katie; Zou, Christopher; Goudy, Laine; Sharma, Rohit; Stevers, Nicholas O.; Pak, Joanna; Foster, Kyla; Payne, Emily; Shai, Anny; Ozawa, Tomoko; de Groot, John F.; Vasudevan, Harish; Phillips, Joanna J.; Raleigh, David R.; Costello, Joseph F.; Murthy, Niren; Gilbert, Luke A.; Berger, Mitchel; Liu, S. John Share Save
INTEGRATIVE SINGLE NUCLEI, SPATIAL, AND FUNCTIONAL GENOMIC ANALYSES REVEAL DNA-PK DRIVES GLIOBLASTOMA RADIORESISTANCE THROUGH TUMOR CELLS AND THE MYELOID MICROENVIRONMENT Liu, J.; Majd, N.; Zou, C.; Mirchia, K.; Pak, J.; Foster, K.; Lin, K.; Casey-Clyde, T.; Seo, K.; Pan, S.; Payne, E.; Vasudevan, H.; Ozawa, T.; Berger, M.; de Groot, J.; Weiss, W.; Gilbert, L.; Raleigh, D. Share Save
In vivo perturb-seq of cancer and microenvironment cells dissects oncologic drivers and radiotherapy responses in glioblastoma Liu, S. John; Zou, Christopher; Pak, Joanna; Morse, Alexandra; Pang, Dillon; Casey-Clyde, Timothy; Borah, Ashir A.; Wu, David; Seo, Kyounghee; O'Loughlin, Thomas; Lim, Daniel A.; Ozawa, Tomoko; Berger, Mitchel S.; Kamber, Roarke A.; Weiss, William A.; Raleigh, David R.; Gilbert, Luke A. Share Save
PLX038A, a long-acting SN-38, penetrates the blood-tumor-brain-barrier, accumulates and releases SN-38 in brain tumors to increase survival of tumor bearing mice Jung, Jinkyu; Schneider, Eric L.; Zhang, Wei; Song, Hua; Zhang, Meili; Chou, William; Meher, Niranjan; VanBrocklin, Henry F.; Barcellos-Hoff, Mary Helen; Ozawa, Tomoko; Gilbert, Mark R.; Santi, Daniel V. Share Save
Synthesis and Preliminary Biological Assessment of Carborane-Loaded Theranostic Nanoparticles to Target Prostate-Specific Membrane Antigen Meher, Niranjan; Seo, Kyounghee; Wang, Sinan; Bidkar, Anil P.; Fogarty, Miko; Dhrona, Suchi; Huang, Xiao; Tang, Ryan; Blaha, Charles; Evans, Michael J.; Raleigh, David R.; Jun, Young-Wook; VanBrocklin, Henry F.; Desai, Tejal A.; Wilson, David M.; Ozawa, Tomoko; Flavell, Robert R. Share Save
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Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma Bhaduri, Aparna; Di Lullo, Elizabeth; Jung, Diane; Mueller, Soren; Crouch, Elizabeth Erin; Espinosa, Carmen Sandoval; Ozawa, Tomoko; Alvarado, Beatriz; Spatazza, Julien; Cadwell, Cathryn Rene; Wilkins, Grace; Velmeshev, Dmitry; Liu, Siyuan John; Malatesta, Martina; Andrews, Madeline Gail; Mostajo-Radji, Mohammed Andres; Huang, Eric Jinsheng; Nowakowski, Tomasz Jan; Lim, Daniel Amos; Diaz, Aaron; Raleigh, David Ronan; Kriegstein, Arnold Richard Share Save
Evaluation of Three Morphologically Distinct Virus-Like Particles as Nanocarriers for Convection-Enhanced Drug Delivery to Glioblastoma Finbloom, Joel A.; Aanei, Ioana L.; Bernard, Jenna M.; Klass, Sarah H.; Elledge, Susanna K.; Han, Kenneth; Ozawa, Tomoko; Nicolaides, Theodore P.; Berger, Mitchel S.; Francis, Matthew B. Share Save
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Precision knockdown of EGFR gene expression using radio frequency electromagnetic energy Ulasov, Ilya V.; Foster, Haidn; Butters, Mike; Yoon, Jae-Geun; Ozawa, Tomoko; Nicolaides, Theodore; Figueroa, Xavier; Hothi, Parvinder; Prados, Michael; Butters, John; Cobbs, Charles Share Save
Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells Lerner, Robin G.; Grossauer, Stefan; Kadkhodaei, Banafsheh; Meyers, Ian; Sidorov, Maxim; Koeck, Katharina; Hashizume, Rintaro; Ozawa, Tomoko; Phillips, Joanna J.; Berger, Mitchel S.; Nicolaides, Theodore; James, C. David; Petritsch, Claudia K. Share Save
NT113, a Pan-ERBB Inhibitor with High Brain Penetrance, Inhibits the Growth of Glioblastoma Xenografts with EGFR Amplification Yoshida, Yasuyuki; Ozawa, Tomoko; Yao, Tsun-Wen; Shen, Wang; Brown, Dennis; Parsa, Andrew T.; Raizer, Jeffrey J.; Cheng, Shi-Yuan; Stegh, Alexander H.; Mazar, Andrew P.; Giles, Francis J.; Sarkaria, Jann N.; Butowski, Nicholas; Nicolaides, Theodore; James, C. David Share Save
Stable luciferase expression does not alter immunologic or in vivo growth properties of GL261 murine glioma cells Clark, Aaron J.; Safaee, Michael; Oh, Taemin; Ivan, Michael E.; Parimi, Vamsi; Hashizume, Rintaro; Ozawa, Tomoko; James, Charles D.; Bloch, Orin; Parsa, Andrew T. Share Save
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