Not logged in High-throughput microfluidic enrichment of circulating tumor cells from entire diagnostic leukapheresis for comprehensive liquid biopsy Mishra, Avanish; Huang, Shih-Bo; Dubash, Taronish; Burr, Risa; Edd, Jon F.; Wittner, Ben S.; Cunneely, Quinn E.; Putaturo, Victor R.; Deshpande, Akansha; Antmen, Ezgi; Gopinathan, Kaustav A.; Otani, Keisuke; Miyazawa, Yoshiyuki; Kwak, Ji Eun; Guay, Sara Y.; Kelly, Justin P.; Walsh, John; Nieman, Linda T.; Galler, Isabella; Chan, PuiYee; Lawrence, Michael S.; Sullivan, Ryan J.; Bardia, Aditya; Micalizzi, Douglas S.; Sequist, Lecia V.; Lee, Richard J.; Franses, Joseph W.; Ting, David T.; Brunker, Patricia A. R.; Maheswaran, Shyamala; Miyamoto, David T.; Haber, Daniel A.; Toner, Mehmet Share Save
Developmental mosaicism underlying EGFR-mutant lung cancer presenting with multiple primary tumors Burr, Risa; Leshchiner, Ignaty; Costantino, Christina L.; Blohmer, Martin; Sundaresan, Tilak; Cha, Justin; Seeger, Karsen; Guay, Sara; Danysh, Brian P.; Gore, Ira; Jacobs, Raquel A.; Slowik, Kara; Utro, Filippo; Rhrissorrakrai, Kahn; Levovitz, Chaya; Barth, Jaimie L.; Dubash, Taronish; Chirn, Brian; Parida, Laxmi; Sequist, Lecia V.; Lennerz, Jochen K.; Mino-Kenudson, Mari; Maheswaran, Shyamala; Naxerova, Kamila; Getz, Gad; Haber, Daniel A. Share Save
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Modeling the novel SERD elacestrant in cultured fulvestrant-refractory HR-positive breast circulating tumor cells Dubash, Taronish D.; Bardia, Aditya; Chirn, Brian; Reeves, Brittany A.; LiCausi, Joseph A.; Burr, Risa; Wittner, Ben S.; Rai, Sumit; Patel, Hitisha; Bihani, Teeru; Arlt, Heike; Bidard, Francois-Clement; Kaklamani, Virginia G.; Aftimos, Philippe; Cortes, Javier; Scartoni, Simona; Fiascarelli, Alessio; Binaschi, Monica; Habboubi, Nassir; Iafrate, A. John; Toner, Mehmet; Haber, Daniel A.; Maheswaran, Shyamala Share Save
Efficacy of novel oral SERD elacestrant in fulvestrant-refractory hormone receptor-positive (HR plus ) breast cancer: a translational investigation Dubash, Taronish D.; Bardia, Aditya; Chirn, Brian; Reeves, Brittany A.; LiCausi, Joseph A.; Burr, Risa; Wittner, Ben S.; Rai, Sumit; Patel, Hitisha; Bihani, Teeru; Arlt, Heike; Bidard, Francois-Clement; Kaklamani, Virginia G.; Aftimos, Philippe; Cortes, Javier; Scartoni, Simona; Binaschi, Monica; Habboubi, Nassir; Iafrate, A. John; Toner, Mehmet; Haber, Daniel A.; Maheswaran, Shyamala Share Save
Mechanisms of genetic predisposition to multifocal lung cancer Burr, Risa; Leshchiner, Ignaty; Costantino, Christina L.; Blohmer, Martin; Sundaresan, Tilak; Cha, Justin; Seeger, Karsen; Guay, Sara; Danysh, Brian P.; Gore, Ira; Jacobs, Raquel A.; Slowik, Kara; Utro, Filippo; Rhrissorrakrai, Kahn; Levovitz, Chaya; Barth, Jaimie L.; Dubash, Taronish; Chirn, Brian; Parida, Laxmi; Sequist, Lecia V.; Mino-Kenudson, Mari; Naxerova, Kamila; Maheswaran, Shyamala; Getz, Gad; Haber, Daniel A. Share Save
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TGF β in the microenvironment induces a physiologically occurring immune-suppressive senescent state Matsuda, Satoru; Revandkar, Ajinkya; Dubash, Taronish D.; Ravi, Arvind; Wittner, Ben S.; Lin, Maoxuan; Morris, Robert; Burr, Risa; Guo, Hongshan; Seeger, Karsen; Szabolcs, Annamaria; Che, Dante; Nieman, Linda; Getz, Gad A.; Ting, David T.; Lawrence, Michael S.; Gainor, Justin; Haber, Daniel A.; Maheswaran, Shyamala Share Save
Association between co-existing genomic alterations and abemaciclib benefit in patients with metastatic hormone receptor-positive breast cancer with ESR1 mutations following disease progression on prior endocrine therapy plus palbociclib or ribociclib Brett, Jamie O.; Dubash, Taronish D.; Niemierko, Andrzej; Mariotti, Veronica; Kim, Leslie S. L.; Xi, Jing; Pandey, Apurva; Dunne, Siobhan; Nasrazadani, Azadeh; Lloyd, Maxwell R.; Spring, Laura M.; Micalizzi, Douglas; Onozato, Maristela; Che, Dante; Brufsky, Adam; Kalinsky, Kevin M.; Ma, Cynthia X.; O'Shaughnessy, Joyce; Han, Hyo S.; Iafrate, A. John; Maheswaran, Shyamala; Haber, Daniel A.; Bardia, Aditya; Wander, Seth A. Share Save
AKT inhibition in combination with endocrine therapy and a CDK4/6 inhibitor (CDK4/6i) in patients with hormone receptor positive (HR+)/HER2 negative metastatic breast cancer (MBC) and prior CDK4/6i exposure: A translational investigation Wander, Seth A.; Micalizzi, Douglas S.; Dubash, Taronish; Juric, Dejan; Spring, Laura M.; Vidula, Neelima; Keenan, Jennifer; Beeler, Maureen; Viscosi, Elene; Che, Dante; Fisher, Elizabeth L.; Hepp, Rachel A.; Moy, Beverly; Isakoff, Steven J.; Ellisen, Leif W.; Supko, Jeffrey G.; Maheswaran, Shyamala; Haber, Daniel A.; Bardia, Aditya Share Save
NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer Guo, Hongsha; Golczer, Gabriel; Wittner, Ben S.; Langenbucher, Adam; Zachariah, Marcus; Dubash, Taronish D.; Hong, Xin; Comaills, Valentine; Burr, Risa; Ebright, Richard Y.; Horwitz, Elad; Vuille, Joanna A.; Hajizadeh, Soroush; Wiley, Devon F.; Reeves, Brittany A.; Zhang, Jia-min; Niederhoffer, Kira L.; Lu, Chenyue; Wesley, Benjamin; Ho, Uyen; Nieman, Linda T.; Toner, Mehmet; Vasudevan, Shobha; Zou, Lee; Mostoslavsky, Raul; Maheswaran, Shyamala; Lawrence, Michael S.; Harber, Daniel A. Share Save
Evaluation of endocrine resistance using ESR1 genotyping of circulating tumor cells and plasma DNA Sundaresan, Tilak K.; Dubash, Taronish D.; Zheng, Zongli; Bardia, Aditya; Wittner, Ben S.; Aceto, Nicola; Silva, Erin J.; Fox, Douglas B.; Liebers, Matthew; Kapur, Ravi; Iafrate, John; Toner, Mehmet; Maheswaran, Shyamala; Haber, Daniel A. Share Save
The Lipogenic Regulator SREBP2 Induces Transferrin in Circulating Melanoma Cells and Suppresses Ferroptosis Hong, Xin; Roh, Whijae; Sullivan, Ryan J.; Wong, Keith H. K.; Wittner, Ben S.; Guo, Hongshan; Dubash, Taronish D.; Sade-Feldman, Moshe; Wesley, Benjamin; Horwitz, Elad; Boland, Genevieve M.; Marvin, Dieuwke L.; Bonesteel, Todd; Lu, Chenyue; Aguet, Francois; Burr, Risa; Freeman, Samuel S.; Parida, Laxmi; Calhoun, Katherine; Jewett, Michelle K.; Nieman, Linda T.; Hacohen, Nir; Naar, Anders M.; Ting, David T.; Toner, Mehmet; Stott, Shannon L.; Getz, Gad; Maheswaran, Shyamala; Haber, Daniel A. Share Save
Identification of Somatically Acquired BRCA1/2 Mutations by cfDNA Analysis in Patients with Metastatic Breast Cancer Vidula, Neelima; Dubash, Taronish; Lawrence, Michael S.; Simoneau, Antoine; Niemierko, Andrzej; Blouch, Erica; Nagy, Becky; Roh, Whijae; Chirn, Brian; Reeves, Brittany A.; Malvarosa, Giuliana; Lennerz, Jochen; Isakoff, Steven J.; Juric, Dejan; Micalizzi, Douglas; Wander, Seth; Spring, Laura; Moy, Beverly; Shannon, Kristen; Younger, Jerry; Lanman, Richard; Toner, Mehmet; Iafrate, A. John; Getz, Gad; Zou, Lee; Ellisen, Leif W.; Maheswaran, Shyamala; Haber, Daniel A.; Bardia, Aditya Share Save
Ultrahigh-throughput magnetic sorting of large blood volumes for epitope-agnostic isolation of circulating tumor cells Mishra, Avanish; Dubash, Taronish D.; Edd, Jon F.; Jewett, Michelle K.; Garre, Suhaas G.; Karabacak, Nezihi Murat; Rabe, Daniel C.; Mutlu, Baris R.; Walsh, John R.; Kapur, Ravi; Stott, Shannon L.; Maheswaran, Shyamala; Haber, Daniel A.; Toner, Mehmet Share Save
Elacestrant (RAD1901) inhibits growth of ex vivo cultured circulating tumor cells derived from hormone receptor-positive metastatic breast cancer (mBC) patients including those harboring ESR1 mutations Dubash, Taronish Dorab; Bardia, Aditya; Reeves, Brittany A.; Chirn, Brian; Szabolcs, Annamaria; Wittner, Ben S.; Iafrate, John; Ting, David; Patel, Hitisha K.; Bihani, Teeru; Toner, Mehmet; Haber, Daniel A.; Maheswaran, Shyamala Share Save
In-flow measurement of cell-cell adhesion using oscillatory inertial microfluidics Mutlu, Baris R.; Dubash, Taronish D.; Dietsche, Claudius; Mishra, Avanish; Ozbey, Arzu; Keim, Kevin; Edd, Jon F.; Haber, Daniel A.; Maheswaran, Shyamala; Toner, Mehmet Share Save
Microfluidic concentration and separation of circulating tumor cell clusters from large blood volumes Edd, Jon F.; Mishra, Avanish; Dubash, Taronish D.; Herrera, Stefan; Mohammad, Ridhwan; Williams, E. Kendall; Hong, Xin; Mutlu, Baris R.; Walsh, John R.; de Carvalho, Fernanda Machado; Aldikacti, Berent; Nieman, Linda T.; Stott, Shannon L.; Kapur, Ravi; Maheswaran, Shyamala; Haber, Daniel A.; Toner, Mehmet Share Save
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Combination Olaparib and Temozolomide in Relapsed Small-Cell Lung Cancer Farago, Anna F.; Yeap, Beow Y.; Stanzione, Marcello; Hung, Yin P.; Heist, Rebecca S.; Marcoux, J. Paul; Zhong, Jun; Rangachari, Deepa; Barbie, David A.; Phat, Sarah; Myers, David T.; Morris, Robert; Kem, Marina; Dubash, Taronish D.; Kennedy, Elizabeth A.; Digumarthy, Subba R.; Sequist, Lecia V.; Hata, Aaron N.; Maheswaran, Shyamala; Haber, Daniel A.; Lawrence, Michael S.; Shaw, Alice T.; Mino-Kenudson, Mari; Dyson, Nicholas J.; Drapkin, Benjamin J. Share Save
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