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CIS is a potent checkpoint in NK cell-mediated tumor immunity (vol 17, pg 816, 2016) Delconte, Rebecca B.; Kolesnik, Tatiana B.; Dagley, Laura F.; Rautela, Jai; Shi, Wei; Putz, Eva M.; Stannard, Kimberley; Zhang, Jian-Guo; Teh, Charis; Firth, Matt; Ushiki, Takashi; Andoniou, Christopher E.; Degli-Esposti, Mariapia A.; Sharp, Phillip P.; Sanvitale, Caroline E.; Infusini, Giuseppe; Liau, Nicholas P. D.; Linossi, Edmond M.; Burns, Christopher J.; Carotta, Sebastian; Gray, Daniel H. D.; Seillet, Cyril; Hutchinson, Dana S.; Belz, Gabrielle T.; Webb, Andrew I.; Alexander, Warren S.; Li, Shawn S.; Bullock, Alex N.; Babon, Jeffrey J.; Smyth, Mark J.; Nicholson, Sandra E.; Huntington, Nicholas D. Share Save
Discovery of BI 7446: A Potent Cyclic Dinucleotide STING Agonist with Broad-Spectrum Variant Activity for the Treatment of Cancer Kuttruff, Christian A. A.; Fleck, Martin; Carotta, Sebastian; Arnhof, Heribert; Bretschneider, Tom; Dahmann, Georg; Gremel, Gabriela; Grube, Achim; Handschuh, Sandra; Heimann, Annekatrin; Hofmann, Marco H. H.; Impagnatiello, Maria A. A.; Nar, Herbert; Rast, Georg; Schaaf, Otmar; Schmidt, Esther; Oost, Thorsten Share Save
Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma Haas, Lisa; Elewaut, Anais; Gerard, Camille L.; Umkehrer, Christian; Leiendecker, Lukas; Pedersen, Malin; Krecioch, Izabela; Hoffmann, David; Novatchkova, Maria; Kuttke, Mario; Neumann, Tobias; da Silva, Ines Pires; Witthock, Harriet; Cuendet, Michel A.; Carotta, Sebastian; Harrington, Kevin J.; Zuber, Johannes; Scolyer, Richard A.; Long, Georgina, V; Wilmott, James S.; Michielin, Olivier; Vanharanta, Sakari; Wiesner, Thomas; Obenauf, Anna C. Share Save
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Potent induction of a tumor-specific immune response by a cyclic dinucleotide STING agonist Gremel, Gabriela; Impagnatiello, Maria A.; Carotta, Sebastian; Schaaf, Otmar; Chetta, Paolo M.; Oost, Thorsten; Zichner, Thomas; Hofmann, Marco; Blake, Sophia; Bretschneider, Tom; Fleck, Martin; Grube, Achim; Nar, Herbert; Rast, Georg; Schmidt, Esther; Klinkhardt, Ute; Arndt-Schmitz, Kirsten; Laux, Thorsten; Zinzalla, Vittoria; Sedgwick, Jonathon; Kraut, Norbert Share Save
Targeting IAP in cancer: BI 891065 a potent small molecule SMAC mimetic that synergizes with immune checkpoint inhibition Aichinger, Martin; Santoro, Valeria; Slavic-Obradovic, Ksenija; Ruhland, Stefanie; Wernitznig, Andreas; Neudolt, Andrea; Schaefer, Markus; Kallenda, Sabine; Zach, Daniel; Olt, Sabine; Salomon, Carina; Rieser, Sarah; Weissenboeck, Martina; Ebner, Florian; Schlattl, Andreas; De Almeida, Melanie Talata; Langlois, Rebecca; Sykora, Martina; Reschke, Markus; Zichner, Thomas; Gerlach, Daniel; Jude, Julian; Fellner, Michaela; Scharn, Dirk; Kraut, Norbert; Moll, Juergen; Zuber, Johannes; Carotta, Sebastian; Impagnatiello, Maria Antonietta; Tontsch-Grunt, Ulrike Share Save
Selective and Potent CDK8/19 Inhibitors Enhance NK-Cell Activity and Promote Tumor Surveillance Hofmann, Marco H.; Mani, Rajeswaran; Engelhardt, Harald; Impagnatiello, Maria A.; Carotta, Sebastian; Kerenyi, Marc; Lorenzo-Herrero, Seila; Boettcher, Jark; Scharn, Dirk; Arnhof, Heribert; Zoephel, Andreas; Schnitzer, Renate; Gerstberger, Thomas; Sanderson, Michael P.; Rajgolikar, Girish; Goswami, Swagata; Vasu, Sumithira; Ettmayer, Peter; Gonzalez, Segundo; Pearson, Mark; McConnell, Darryl B.; Kraut, Norbert; Muthusamy, Natarajan; Moll, Juergen Share Save
Selective and potent CDK8 inhibitors enhance NK cell activity and promote tumor surveillance Hofmann, Marco H.; Mani, Rajeswaran; Engelhardt, Harald; Impagnatiello, Maria A.; Carotta, Sebastian; Kerenyi, Marc A.; Lorenzo-Herrero, Seila; Boettcher, Jark; Scharn, Dirk; Arnhof, Heribert; Zoephel, Andreas; Schnitzer, Renate; Gerstberger, Thomas; Rajgolikar, Girish; Goswami, Swagata; Vasu, Sumithira; Ettmayer, Peter; Gonzalez, Segundo R.; Pearson, Mark; McConnell, Darryl B.; Kraut, Norbert; Muthusamy, Natarajan; Moll, Juergen Share Save
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LMP2 immunoproteasome promotes lymphocyte survival by degrading apoptotic BH3-only proteins Zanker, Damien; Pang, Kenneth; Oveissi, Sara; Lu, Chunni; Faou, Pierre; Nowell, Cameron; Mbogo, George W.; Carotta, Sebastian; Quillici, Cathy; Karupiah, Guna; Hibbs, Margaret L.; Nutt, Stephen L.; Neeson, Paul; Puthalakath, Hamsa; Chen, Weisan Share Save
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Development of selective and potent CDK8 inhibitors that increase NK cell activity, which translates in tumor surveillance Hofmann, Marco H.; Engelhardt, Harald; Carotta, Sebastian; Arnhof, Heribert; Scharn, Dirk; Kerenyi, Marc; Mayer, Moritz; Gmaschitz, Gerhard; Egger, Georg; Engelhardt, Christian; Sanderson, Michael; Impagnatiello, Maria A.; Schnitzer, Renate; Pearson, Mark; McConnell, Darryl; Kraut, Norbert; Moll, Jurgen Share Save
Deciphering the Innate Lymphoid Cell Transcriptional Program Seillet, Cyril; Mielke, Lisa A.; Amann-Zalcenstein, Daniela B.; Su, Shian; Gao, Jerry; Almeida, Francisca F.; Shi, Wei; Ritchie, Matthew E.; Naik, Shalin H.; Huntington, Nicholas D.; Carotta, Sebastian; Belz, Gabrielle T. Share Save
CIS is a potent checkpoint in NK cell-mediated tumor immunity Delconte, Rebecca B.; Kolesnik, Tatiana B.; Dagley, Laura F.; Rautela, Jai; Shi, Wei; Putz, Eva M.; Stannard, Kimberley; Zhang, Jian-Guo; Teh, Charis; Firth, Matt; Ushiki, Takashi; Andoniou, Christopher E.; Degli-Esposti, Mariapia A.; Sharp, Phillip P.; Sanvitale, Caroline E.; Infusini, Giuseppe; Liau, Nicholas P. D.; Linossi, Edmond M.; Burns, Christopher J.; Carotta, Sebastian; Gray, Daniel H. D.; Seillet, Cyril; Hutchinson, Dana S.; Belz, Gabrielle T.; Webb, Andrew I.; Alexander, Warren S.; Li, Shawn S.; Bullock, Alex N.; Babon, Jeffery J.; Smyth, Mark J.; Nicholson, Sandra E.; Huntington, Nicholas D. Share Save
Novel non-canonical role of STAT1 in Natural Killer cell cytotoxicity Putz, Eva Maria; Majoros, Andrea; Gotthardt, Dagmar; Prchal-Murphy, Michaela; Zebedin-Brandl, Eva Maria; Fux, Daniela Alexandra; Schlattl, Andreas; Schreiber, Robert D.; Carotta, Sebastian; Mueller, Mathias; Gerner, Christopher; Decker, Thomas; Sexl, Veronika Share Save
PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia Pang, S. H. M.; Minnich, M.; Gangatirkar, P.; Zheng, Z.; Ebert, A.; Song, G.; Dickins, R. A.; Corcoran, L. M.; Mullighan, C. G.; Busslinger, M.; Huntington, N. D.; Nutt, S. L.; Carotta, S. Share Save
The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15 Delconte, Rebecca B.; Shi, Wei; Sathe, Priyanka; Ushiki, Takashi; Seillet, Cyril; Minnich, Martina; Kolesnik, Tatiana B.; Rankin, Lucille C.; Mielke, Lisa A.; Zhang, Jian-Guo; Busslinger, Meinrad; Smyth, Mark J.; Hutchinson, Dana S.; Nutt, Stephen L.; Nicholson, Sandra E.; Alexander, Warren S.; Corcoran, Lynn M.; Vivier, Eric; Belz, Gabrielle T.; Carotta, Sebastian; Huntington, Nicholas D. Share Save
Complementarity and redundancy of IL-22-producing innate lymphoid cells Rankin, Lucille C.; Girard-Madoux, Mathilde J. H.; Seillet, Cyril; Mielke, Lisa A.; Kerdiles, Yann; Fenis, Aurore; Wieduwild, Elisabeth; Putoczki, Tracy; Mondot, Stanislas; Lantz, Olivier; Demon, Dieter; Papenfuss, Anthony T.; Smyth, Gordon K.; Lamkanfi, Mohamed; Carotta, Sebastian; Renauld, Jean-Christophe; Shi, Wei; Carpentier, Sabrina; Soos, Tim; Arendt, Christopher; Ugolini, Sophie; Huntington, Nicholas D.; Bez, Gabrielle T.; Vivier, Eric Share Save
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