Not logged in Discovery of long-acting APOC3 siRNA for treating patients with hypertriglyceridemia Prakash, Thazha P.; Mullick, Adam E.; Riney, Stan; Yu, Jinghua; Nikan, Mehran; Quirk, Clare; Crutchfield, Amanda; Damle, Sagar S.; Klein, Stephanie; Swayze, Eric E. Share Save
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Single alkyl phosphonate modification of the siRNA backbone in the seed region enhances specificity and therapeutic profile Nikan, Mehran; Li, Qingfeng; Tanowitz, Michael; Li, Hongda; Damle, Sagar; Annoual, Marie; Galindo-Murillo, Rodrigo; Low, Audrey; Klein, Stephanie; Quirk, Clare; Vasquez, Guillermo; Wan, W. Brad; Watt, Andrew T.; Migawa, Michael T.; Swayze, Eric E.; Prakash, Thazha P. Share Save
Interferon-α receptor antisense oligonucleotides reduce neuroinflammation and neuropathology in a mouse model of cerebral interferonopathy Viengkhou, Barney; Hong, Christine; Mazur, Curt; Damle, Sagar; Gallo, Nicholas B.; Fang, Terry C.; Henry, Kate; Campbel, Iain L.; Kamme, Fredrik; Hofer, Markus J. Share Save
GOLGA8 increases bulk antisense oligonucleotide uptake and activity in mammalian cells McMahon, Moira A.; Rahdar, Meghdad; Mukhopadhyay, Swagatam; Bui, Huynh-Hoa; Hart, Christopher; Damle, Sagar; Courtney, Margo; Baughn, Michael W.; Cleveland, Don W.; Bennett, Frank Share Save
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Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy Beverborg, Niels Grote; Spater, Daniela; Knoll, Ralph; Hidalgo, Alejandro; Yeh, Steve T.; Elbeck, Zaher; Sillje, Herman H. W.; Eijgenraam, Tim R.; Siga, Humam; Zurek, Magdalena; Palmer, Malin; Pehrsson, Susanne; Albery, Tamsin; Bomer, Nils; Hoes, Martijn F.; Boogerd, Cornelis J.; Frisk, Michael; van Rooij, Eva; Damle, Sagar; Louch, William E.; Wang, Qing-Dong; Fritsche-Danielson, Regina; Chien, Kenneth R.; Hansson, Kenny M.; Mullick, Adam E.; de Boer, Rudolf A.; van der Meer, Peter Share Save
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2′-O-methoxyethyl splice-switching oligos correct splicing from IVS2-745 β-thalassemia patient cells restoring hemoglobin A production and chain rebalance Dong, Alisa; Ghiaccio, Valentina; Motta, Irene; Guo, Shuling; Peralta, Raechel; Freier, Susan M.; Watt, Andy; Damle, Sagar; Ikawa, Yasuhiro; Jarocha, Danuta; Chappell, Maxwell; Stephanou, Coralea; Delbini, Paola; Chen, Connie; Christou, Soteroula; Kleanthous, Marina; Smith-Whitley, Kim; Manwani, Deepa; Casu, Carla; Abdulmalik, Osheiza; Cappellini, Maria Domenica; Rivella, Stefano; Breda, Laura Share Save
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PMP22 antisense oligonucleotides reverse Charcot-Marie-Tooth disease type 1A features in rodent models Zhao, Hien Tran; Damle, Sagar; Ikeda-Lee, Karli; Kuntz, Steven; Li, Jian; Mohan, Apoorva; Kim, Aneeza; Hung, Gene; Scheideler, Mark A.; Scherer, Steven S.; Svaren, John; Swayze, Eric E.; Kordasiewicz, Holly B. Share Save
Antisense oligonucleotides targeting translation inhibitory elements in 5′ UTRs can selectively increase protein levels Liang, Xue-hai; Sun, Hong; Shen, Wen; Wang, Shiyu; Yao, Joyee; Migawa, Michael T.; Huynh-Hoa Bui; Damle, Sagar S.; Riney, Stan; Graham, Mark J.; Crooke, Rosanne M.; Crooke, Stanley T. Share Save
Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment Kueh, Hao Yuan; Yui, Mary A.; Ng, Kenneth K. H.; Pease, Shirley S.; Zhang, Jingli A.; Damle, Sagar S.; Freedman, George; Siu, Sharmayne; Bernstein, Irwin D.; Elowitz, Michael B.; Rothenberg, Ellen V. Share Save
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GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate Van de Walle, Inge; Dolens, Anne-Catherine; Durinck, Kaat; De Mulder, Katrien; Van Loocke, Wouter; Damle, Sagar; Waegemans, Els; De Medts, Jelle; Velghe, Imke; De Smedt, Magda; Vandekerckhove, Bart; Kerre, Tessa; Plum, Jean; Leclercq, Georges; Rothenberg, Ellen V.; Van Vlierberghe, Pieter; Speleman, Frank; Taghon, Tom Share Save
GATA-3 Dose-Dependent Checkpoints in Early T Cell Commitment Scripture-Adams, Deirdre D.; Damle, Sagar S.; Li, Long; Elihu, Koorosh J.; Qin, Shuyang; Arias, Alexandra M.; Butler, Robert R., III; Champhekar, Ameya; Zhang, Jingli A.; Rothenberg, Ellen V. Share Save
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