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Omics-based identification of an NRF2-related auranofin resistance signature in cancer: Insights into drug repurposing Falchetti, Marcelo; Delgobo, Marina; Zancanaro, Helena; Almeida, Karoline; Neves, Raquel Nascimento das; dos Santos, Barbara; Stefanes, Natalia Marceli; Bishop, Alexander; Santos-Silva, Maria Claudia; Zanotto-Filho, Alfeu Share Save
Thioredoxin reductase-1 levels are associated with NRF2 pathway activation and tumor recurrence in non-small cell lung cancer Delgobo, Marina; Goncalves, Rosangela Mayer; Delazeri, Marco Antonio; Falchetti, Marcelo; Zandona, Alessandro; das Neves, Raquel Nascimento; Almeida, Karoline; Fagundes, Adriane Cristina; Gelain, Daniel Pens; Fracasso, Joao Isidro; de Macedo, Guilherme Baroni; Priori, Leonardo; Bassani, Nicklas; Bishop, Alexander James Roy; Forcelini, Cassiano Mateus; Fonseca Moreira, Jose Claudio; Zanotto-Filho, Alfeu Share Save
Role of toll-like receptor 4 and sex in 6-hydroxydopamine-induced behavioral impairments and neurodegeneration in mice Somensi, Nauana; Lopes, Samantha Cristiane; Gasparotto, Juciano; Goncalves, Rosangela Mayer; Tiefensee-Ribeiro, Camila; Peixoto, Daniel Oppermann; Brum, Pedro Ozorio; Pinho, Cibele Martins; Agnes, Jonathan Paulo; Santos, Lucas; de Oliveira, Jade; Spiller, Fernando; Fonseca Moreira, Jose Claudio; Zanotto-Filho, Alfeu; Prediger, Rui Daniel; Gelain, Daniel Pens Share Save
Antioxidants Improve Oxaliplatin-Induced Peripheral Neuropathy in Tumor-Bearing Mice Model: Role of Spinal Cord Oxidative Stress and Inflammation Agnes, Jonathan Paulo; dos Santos, Vitoria Wibbelt; das Neves, Raquel Nascimento; Goncalves, Rosangela Mayer; Delgobo, Marina; Girardi, Carolina Saibro; Luckemeyer, Debora Denardin; Ferreira, Marcella de Amorim; Macedo-Junior, Sergio Jose; Lopes, Samantha Cristiane; Spiller, Fernando; Gelain, Daniel Pens; Moreira, Jose Claudio Fonseca; Prediger, Rui Daniel; Ferreira, Julian; Zanotto-Filho, Alfeu Share Save
COX-2 promotes mammary adipose tissue inflammation, local estrogen biosynthesis, and carcinogenesis in high-sugar/fat diet treated mice Goncalves, Rosangela Mayer; Delgobo, Marina; Agnes, Jonathan Paulo; das Neves, Raquel Nascimento; Falchetti, Marcelo; Casagrande, Tuany; Vargas Garcia, Ana Paula; Vieira, Thaynan Cunha; Somensi, Nauana; Bruxel, Maciel Alencar; Gasparin Bueno Mendes, Daniel Augusto; Rafacho, Alex; Bafica, Andre; Gelain, Daniel Pens; Fonseca Moreira, Jose Claudio; Cassali, Geovanni Dantas; Roy Bishop, Alexander James; Zanotto-Filho, Alfeu Share Save
ConBr lectin modulates MAPKs and Akt pathways and triggers autophagic glioma cell death by a mechanism dependent upon caspase-8 activation Wolin, Ingrid A., V; Heinrich, Isabella A.; Nascimento, Ana Paula M.; Welter, Priscilla G.; Sosa, Liliana del, V; De Paul, Ana Lucia; Zanotto-Filho, Alfeu; Nedel, Claudia Beatriz; Lima, Lara Dias; Silva Osterne, Vinicius Jose; Pinto-Junior, Vanir Reis; Nascimento, Kyria S.; Cavada, Benildo S.; Leal, Rodrigo B. Share Save
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Efficient identification of novel anti-glioma lead compounds by machine learning models Neves, Bruno Junior; Agnes, Jonathan Paulo; Gomes, Marcelo do Nascimento; Henriques Donza, Marcio Roberto; Goncalves, Rosangela Mayer; Delgobo, Marina; de Souza Neto, Lauro Ribeiro; Senger, Mario Roberto; Silva-Junior, Floriano Paes; Ferreira, Sabrina Baptista; Zanotto-Filho, Alfeu; Andrade, Carolina Horta Share Save
BRCA-1 depletion impairs pro-inflammatory polarization and activation of RAW 264.7 macrophages in a NF-κB-dependent mechanism Morrone, Maurilio da Silva; Somensi, Nauana; Franz, Lucas; Ramos, Vitor de Miranda; Gasparotto, Juciano; da Rosa, Helen Tais; Sartori, Marcelo; Figueiro, Fabricio; Gelain, Daniel Pens; Zanotto-Filho, Alfeu; Fonseca Moreira, Jose Claudio Share Save
Lectin from Dioclea violacea induces autophagy in U87 glioma cells Nascimento, Ana Paula M.; Wolin, Ingrid A. V.; Welter, Priscilla G.; Heinrich, Isabella A.; Zanotto-Filho, Alfeu; Osterne, Vinicius J. S.; Lossio, Claudia F.; Silva, Mayara T. L.; Nascimento, Kyria S.; Cavada, Benildo S.; Leal, Rodrigo B. Share Save
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Alkylating Agent-Induced NRF2 Blocks Endoplasmic Reticulum Stress-Mediated Apoptosis via Control of Glutathione Pools and Protein Thiol Homeostasis Zanotto-Filho, Alfeu; Masamsetti, V. Pragathi; Loranc, Eva; Tonapi, Sonal S.; Gorthi, Aparna; Bernard, Xavier; Goncalves, Rosangela Mayer; Moreira, Jose C. F.; Chen, Yidong; Bishop, Alexander J. R. Share Save
Oral administration of curcumin relieves behavioral alterations and oxidative stress in the frontal cortex, hippocampus, and striatum of ovariectomized Wistar rats Da Silva Morrone, Maurilio; Schnorr, Carlos Eduardo; Behr, Guilherme Antonio; Gasparotto, Juciano; Bortolin, Rafael Calixto; Moresco, Karla Suzana; Bittencourt, Leonardo; Zanotto-Filho, Alfeu; Gelain, Daniel Pens; Fonseca Moreira, Jose Claudio Share Save
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