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K

Katharina Rox

Helmholtz Centre for Infection Research

20H-index
112Paper Count
4.6KCitation Count
Published Papers 36
Publication Date
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Metronidazole and ether derivatives target Helicobacter pylori via simultaneous stress induction and inhibition
errNature Microbiology
IF19.4
err2026-03-18
err0
errOAAI
errMichaela K. Fiedler; Marianne S. I. Pandler; Ruolan Gong; Sonja Fuchs; Katharina Rox; Verena Friedrich; Dietmar Pfeiffer; Dharmesh Singh; Till Reinhardt; Cora Mibus; Matthias Huber; Corinna R. Hess; Raquel Mejías-Luque; Markus Gerhard; Michael Groll; Stephan A. Sieber
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Multiparameter Optimization of Pseudomonas aeruginosa Elastase Inhibitors for Systemic Administration
errJournal of Medicinal Chemistry
IF6.8
err2026-02-05
err0
errOAAI
errAhmed S. Abdelsamie; Jelena Konstantinović; Andreas M. Kany; Christian Schütz; Dominik Kolling; Samira Speicher; Andreas Klein; Roya Shafiei; Mélodie Bouté; Katharina Mundry; Yu Mi Park; Brigitta Loretz; Rolf Müller; Jean-Michel Sallenave; Claus-Michael Lehr; Jesko Koehnke; Katharina Rox; Jörg Haupenthal; Anna K. H. Hirsch
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Targeting bacterial kinases as a strategy to counteract antibiotic resistance
errCommunications Chemistry
IF6.2
err2025-12-04
err0
errOAAI
errVanessa Buffa; Julien Kowalewski; Guoman Qi; Robin Deutscher; Matijas Cica; Marion Richardoz; Mathilde Tomaszczyk; Andreas Krämer; Stefan Knapp; Catherine Dunyach-Remy; Katharina Rox; Jean-Francois Guichou; Corinne Lionne; Felix Hausch
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Synthesis and Evaluation of DNA Cross-linkers by Click Chemistry-Mediated Heterodimerization of Nor-Tomaymycins
errChemistry – A European Journal
IF3.7
err2025-08-22
err0
errOAAI
errDr. Julia Friederich; Dr. Katharina Rox; Dr. Hazel L. S. Fuchs; Dr. Md. Mahbub Hasan; Patrick Raunft; Prof. Dr. David E. Thurston; Prof. Dr. Keith R. Fox; Prof. Dr. Khondaker Miraz Rahman; Prof. Dr. Mark Brönstrup
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Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality
errCell Genomics
IF9
err2025-05-09
err0
errOAAI
errChelsea E. Cunningham; Frederick S. Vizeacoumar; Yue Zhang; Liliia Kyrylenko; Simon Both; Vincent Maranda; He Dong; Jared D.W. Price; Peng Gao; Konrad Wagner; Yingwen Wu; Mary Lazell-Wright; Ashtalakshmi Ganapathysamy; Rithik Hari; Kalpana K. Bhanumathy; Connor Denomy; Anjali Saxena; Jeff P. Vizeacoumar; Alain Morejon Morales; Faizaan Khan; Shayla Mosley; Angie Chen; Tetiana Katrii; Ben G.E. Zoller; Karthic Rajamanickam; Prachi Walke; Lihui Gong; Hardikkumar Patel; Hussain Elhasasna; Renuka Dahiya; Omar Abuhussein; Anton Dmitriev; Tanya Freywald; Erika Prando Munhoz; Eytan Ruppin; Joo Sang Lee; Katharina Rox; Martin Koebel; Laura Hopkins; Cheng Han Lee; Sunil Yadav; Gilles Gasparoni; Jörn Walter; Anand Krishnan; Raju Datla; Behzad Toosi; Kristi Baker; Jalna Meens; David W. Cescon; Laurie Ailles; Scot C. Leary; Yuliang Wu; Martin Empting; Alexandra K. Kiemer; Andrew Freywald; Franco J. Vizeacoumar
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Dipeptidic Phosphonates: Potent Inhibitors of Pseudomonas aeruginosa Elastase B Showing Efficacy in a Murine Keratitis Model
errADVANCED SCIENCE
IF14.1
err2025-02-19
err0
errOAAI
errKiefer, AF; Schütz, C; Englisch, CN; Kolling, D; Speicher, S; Kany, AM; Shafiei, R; Wadood, NA; Aljohmani, A; Wirschem, N; Jumde, RP; Klein, A; Sikandar, A; Park, YM; Krasteva-Christ, G; Yildiz, D; Abdelsamie, AS; Rox, K; Köhnke, J; Müller, R; Bischoff, M; Haupenthal, J; Hirsch, AKH
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Structure-Based Optimization of Pyridone α-Ketoamides as Inhibitors of the SARS-CoV-2 Main Protease
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-01-16
err1
errOAAI
errAkula, Ravi Kumar; El Kilani, Haifa; Metzen, Alina; Roeske, Judith; Zhang, Kaixuan; Goehl, Matthias; Arisetti, Nanaji; Marsh, Graham P.; Maple, Hannah J.; Cooper, Mark S.; Karadogan, Burhan; Jochmans, Dirk; Neyts, Johan; Rox, Katharina; Hilgenfeld, Rolf
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Synthetic studies on the tetrasubstituted D-ring of cystobactamids lead to potent terephthalic acid antibiotics
errCOMMUNICATIONS CHEMISTRY
IF6.2
err2024-11-05
err0
errOAAI
errStappert, Moritz; Kohnhaeuser, Daniel; Seedorf, Tim; Coetzee, Janetta; Rox, Katharina; Fuchs, Hazel L. S.; Cirnski, Katarina; Leitner, Christian; Herrmann, Jennifer; Kirschning, Andreas; Mueller, Rolf; Broenstrup, Mark
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A Targeted Click-to-Release Activation of the Last-Resort Antibiotic Colistin Reduces its Renal Cell Toxicity
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2024-10-16
err0
errOAAI
errCharoenpattarapreeda, Jiraborrirak; Tegge, Werner; Xu, Chunfa; Harmrolfs, Kirsten; Hinkelmann, Bettina; Wullenkord, Hannah; Hotop, Sven-Kevin; Beutling, Ulrike; Rox, Katharina; Broenstrup, Mark
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Targeting Plasmodium falciparum IspD in the Methyl-D-erythritol Phosphate Pathway: Urea-Based Compounds with Nanomolar Potency on Target and Low-Micromolar Whole-Cell Activity
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-09-20
err1
errOAAI
errWillocx, Daan; Bizzarri, Lorenzo; Alhayek, Alaa; Kannan, Deepika; Bravo, Patricia; Illarionov, Boris; Rox, Katharina; Lohse, Jonas; Fischer, Markus; Kany, Andreas M.; Hahne, Hannes; Rottmann, Matthias; Witschel, Matthias; Odom John, Audrey; Hamed, Mostafa M.; Diamanti, Eleonora; Hirsch, Anna K. H.
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Development of Fragment-Based Inhibitors of the Bacterial Deacetylase LpxC with Low Nanomolar Activity
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-09-20
err0
errOAAI
errMielniczuk, Sebastian; Hoff, Katharina; Baselious, Fady; Li, Yunqi; Haupenthal, Joerg; Kany, Andreas M.; Riedner, Maria; Rohde, Holger; Rox, Katharina; Hirsch, Anna K. H.; Krimm, Isabelle; Sippl, Wolfgang; Holl, Ralph
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Optimization of the Central α-Amino Acid in Cystobactamids to the Broad-Spectrum, Resistance-Breaking Antibiotic CN-CC-861
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-09-20
err1
errOAAI
errKohnhaeuser, Daniel; Seedorf, Tim; Cirnski, Katarina; Heimann, Dominik; Coetzee, Janetta; Sordello, Sylvie; Richter, Jana; Stappert, Moritz; Sabuco, Jean-Francois; Corbett, David; Bacque, Eric; Rox, Katharina; Herrmann, Jennifer; Vassort, Aurelie; Mueller, Rolf; Kirschning, Andreas; Broenstrup, Mark
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Glycomimetics as Candidates for Treatment and Prevention of Catheter-associated Biofilms Formed by Pseudomonas aeruginosa
errEUROPEAN UROLOGY FOCUS
IF5.6
err2024-09-01
err1
errOAAI
errVogel, Christian; Rox, Katharina; Wagenlehner, Florian; Titz, Alexander
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Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor
errNATURE COMMUNICATIONS
IF15.7
err2024-02-08
err6
errOAAI
errSake, Svenja M.; Zhang, Xiaoyu; Rajak, Manoj Kumar; Urbanek-Quaing, Melanie; Carpentier, Arnaud; Gunesch, Antonia P.; Grethe, Christina; Matthaei, Alina; Rueckert, Jessica; Galloux, Marie; Larcher, Thibaut; Le Goffic, Ronan; Hontonnou, Fortune; Chatterjee, Arnab K.; Johnson, Kristen; Morwood, Kaycie; Rox, Katharina; Elgaher, Walid A. M.; Huang, Jiabin; Wetzke, Martin; Hansen, Gesine; Fischer, Nicole; Eleouet, Jean-Francois; Rameix-Welti, Marie-Anne; Hirsch, Anna K. H.; Herold, Elisabeth; Empting, Martin; Lauber, Chris; Schulz, Thomas F.; Krey, Thomas; Haid, Sibylle; Pietschmann, Thomas
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Pharmacokinetic and pharmacodynamic evaluation of the atypical tetracyclines chelocardin and amidochelocardin in murine infection models
errMICROBIOLOGY SPECTRUM
IF3.8
err2024-01-11
err2
errOAAI
errRox, Katharina; Jansen, Rolf; Lukezic, Tadeja; Greweling-Pils, Marina; Herrmann, Jennifer; Miethke, Marcus; Huettel, Stephan; Hennessen, Fabienne; Abou Fayad, Antoine; Holzhausen, Cornelia; Lundberg, Carina Vingsbo; Teague, Joanne; Sudarman, Enge; Buelter, Lisa; Hesterkamp, Thomas; Stadler, Marc; Broenstrup, Mark; Mueller, Rolf
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Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections
errACS CENTRAL SCIENCE
IF10.4
err2023-10-27
err7
errOAAI
errKonstantinovic, Jelena; Kany, Andreas M.; Alhayek, Alaa; Abdelsamie, Ahmed S.; Sikandar, Asfandyar; Voos, Katrin; Yao, Yiwen; Andreas, Anastasia; Shafiei, Roya; Loretz, Brigitta; Schoenauer, Esther; Bals, Robert; Brandstetter, Hans; Hartmann, Rolf W.; Ducho, Christian; Lehr, Claus-Michael; Beisswenger, Christoph; Mueller, Rolf; Rox, Katharina; Haupenthal, Joerg; Hirsch, Anna K. H.
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Sorangicin A Is Active against Chlamydia in Cell Culture, Explanted Fallopian Tubes, and Topical In Vivo Treatment
errANTIBIOTICS-BASEL
IF4.6
err2023-04-22
err2
errOAAI
errGraspeuntner, Simon; Koethke, Katharina; Scholz, Celeste; Semmler, Lea; Lupatsii, Mariia; Kirchhoff, Laura; Herrmann, Jennifer; Rox, Katharina; Wittstein, Kathrin; Kaeding, Nadja; Hanker, Lars C.; Stadler, Marc; Broenstrup, Mark; Mueller, Rolf; Shima, Kensuke; Rupp, Jan
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Synthesis and Characterization of DOTAM-Based Sideromycins for Bacterial Imaging and Antimicrobial Therapy
errACS INFECTIOUS DISEASES
IF3.8
err2023-01-31
err10
errOAAI
errPeukert, Carsten; Rox, Katharina; Karge, Bianka; Hotop, Sven-Kevin; Broenstrup, Mark
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Neutralizing the Impact of the Virulence Factor LecA from Pseudomonas aeruginosa on Human Cells with New Glycomimetic Inhibitors
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2023-01-10
err14
errOAAI
errZahorska, Eva; Rosato, Francesca; Stober, Kai; Kuhaudomlarp, Sakonwan; Meiers, Joscha; Hauck, Dirk; Reith, Dorina; Gillon, Emilie; Rox, Katharina; Imberty, Anne; Roemer, Winfried; Titz, Alexander
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Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle
errADVANCED SCIENCE
IF14.1
err2023-01-03
err13
errOAAI
errHamed, Mostafa M.; Abdelsamie, Ahmed S.; Rox, Katharina; Schuetz, Christian; Kany, Andreas M.; Roehrig, Teresa; Schmelz, Stefan; Blankenfeldt, Wulf; Arce-Rodriguez, Alejandro; Borrero-de Acuna, Jose Manuel; Jahn, Dieter; Rademacher, Jessica; Ringshausen, Felix C.; Cramer, Nina; Tuemmler, Burkhard; Hirsch, Anna K. H.; Hartmann, Rolf W.; Empting, Martin
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Research Directions

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Co-authors
Cooperation Journals
J
Johannes Lehmann
H-index: 122 · Papers: 1.2K
M
Markus M. Lerch
H-index: 117 · Papers: 1.1K
S
Stefan Knapp
H-index: 111 · Papers: 1.3K
J
Johan Neyts
H-index: 100 · Papers: 1.1K
B
Bernhard Küster
H-index: 96 · Papers: 519
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