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SaveImpairing hydrolase transport machinery prevents human melanoma metastasis
Nordlinger, Alice; Del Rio, Justine; Parikh, Shivang; Thomas, Laetitia; Parikh, Roma; Vaknine, Hananya; Brenner, Ronen; Baschieri, Francesco; Robert, Aude; Khaled, Mehdi Share Save In vitro evaluation of NA1-115-7-loaded nanoemulsions, an MCL-1-specific inhibitor of natural origin, intended to treat B-cell lymphoproliferative disorders after oral administrationSeguy, Line; Daressy, Florian; Lahlil, Sophia; Corvaisier, Sophie; Dumontet, Vincent; Litaudon, Marc; Apel, Cecile; Roussi, Fanny; Wiels, Joelle; Robert, Aude; Groo, Anne-Claire; Malzert-Freon, Aurelie Share Save NA1-115-7, from Zygogynum pancheri, is a new selective MCL-1 inhibitor inducing the apoptosis of hematological cancer cells but non-toxic to normal blood cells or cardiomyocytesDaressy, Florian; Seguy, Line; Favre, Loetitia; Corvaisier, Sophie; Apel, Cecile; Groo, Anne-Claire; Litaudon, Marc; Dumontet, Vincent; Malzert-Freon, Aurelie; Desrat, Sandy; Roussi, Fanny; Robert, Aude; Wiels, Joelle Share Save Share Save Drimane Derivatives as the First Examples of Covalent BH3 Mimetics that Target MCL-1Daressy, Florian; Malard, Florian; Seguy, Line; Guerineau, Vincent; Apel, Cecile; Dumontet, Vincent; Robert, Aude; Groo, Anne-Claire; Litaudon, Marc; Bignon, Jerome; Desrat, Sandy; Malzert-Freon, Aurelie; Wiels, Joelle; Lescop, Ewen; Roussi, Fanny Share Save Share Save Share Save Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma (vol 33, pg 2429, 2019)Harrington, Colleen T.; Sotillo, Elena; Robert, Aude; Hayer, Katharina E.; Bogusz, Agata M.; Psathas, James; Yu, Duonan; Taylor, Deanne; Dang, Chi V.; Klein, Peter S.; Hogarty, Michael D.; Geoerger, Birgit; El-Deiry, Wafik S.; Wiels, Joelle; Thomas-Tikhonenko, Andrei Share Save Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphomaHarrington, Colleen T.; Sotillo, Elena; Robert, Aude; Hayer, Katharina E.; Bogusz, Agata M.; Psathas, James; Yu, Duonan; Taylor, Deanne; Dang, Chi, V; Klein, Peter; Hogarty, Michael D.; Geoerger, Birgit; El-Deiry, Wafik S.; Wiels, Joelle; Thomas-Tikhonenko, Andrei Share Save Developmental and cancer-associated plasticity of DNA replication preferentially targets GC-poor, lowly expressed and late-replicating regions (vol 46, pg 10157, 2018)Wu, Xia; Kabalane, Hadi; Kahli, Malik; Petryk, Nataliya; Laperrousaz, Bastien; Jaszczyszyn, Yan; Drillon, Guenola; Nicolini, Frank-Emmanuel; Perot, Gaelle; Robert, Aude; Fund, Cedric; Chibon, Frederic; Xia, Ruohong; Wiels, Joelle; Argoul, Francoise; Maguer-Satta, Veronique; Arneodo, Alain; Audit, Benjamin; Hyrien, Olivier Share Save Developmental and cancer-associated plasticity of DNA replication preferentially targets GC-poor, lowly expressed and late-replicating regionsWu, Xia; Kabalane, Hadi; Kahli, Malik; Petryk, Nataliya; Laperrousaz, Bastien; Jaszczyszyn, Yan; Drillon, Guenola; Nicolini, Frank-Emmanuel; Perot, Gaelle; Robert, Aude; Fund, Cederic; Chibon, Frederic; Xia, Ruohong; Wiels, Joelle; Argoul, Francois; Maguer-Satta, Veronique; Arneodo, Alain; Audit, Benjamin; Hyrien, Olivier Share Save Dual inhibitors of the pro-survival proteins Bcl-2 and Mcl-1 derived from natural compound meiogynin AAbou Samra, Alma; Robert, Aude; Gov, Crystal; Favre, Loetitia; Eloy, Laure; Jacquet, Eric; Bignon, Jerome; Wiels, Joelle; Desrat, Sandy; Roussi, Fanny Share Save Share Save Share Save Share Save 
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