Not logged in Myeloperoxidase aggravates thoracic aortic aneurysm formation in Marfan disease Mehrkens, Dennis; Dohr, Johannes; Nettersheim, Felix Sebastian; Ballmann, Felix; Bastigkeit, Jil; Bruckner, Alexander; Geissen, Simon; De Vore, Lauren; Fitsch, Cedric; Diekmann, Chris; De La Fuente-alonso, Andrea; Schelemei, Patrik; Picard, Felix Ruben; Kochen, Malte; Arkenberg, Per; Rappenecker, Anna; Ahdab, Maysam; Nemade, Harshal; Narayan, Suchitra; Braumann, Simon; Kreuzberg, Wiebke; Hof, Alexander; Guthoff, Henning; Mensah, Benedicta Quaye; Lechner, Sebastian; Guala, Andrea; Evangelista, Artur; Teixido-Tura, Gisela; Nistal, J. Francisco; Campanero, Miguel R.; Kaemmerer, Harald; Wolf, Zsuzsanna; Holdenrieder, Stefan; Groenink, Maarten; Van Andel, Mitzi; Mieremet, Arnout; Pfeiler, Susanne; Gerdes, Norbert; Flogel, Ulrich; Zimmermann, Laura-Maria; Sengle, Gerhard; Eich, Marie-Lisa; Schomig-Markiefka, Birgid; Adam, Matti; Fleischmann, Bernd K.; Wenzel, Daniela; Redondo, Juan Miguel; De Waard, Vivian; Klinke, Anna; Baldus, Stephan; Mollenhauer, Martin; Winkels, Holger Share Save
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Pharmacological Gq inhibition induces strong pulmonary vasorelaxation and reverses pulmonary hypertension Seidinger, Alexander; Roberts, Richard; Bai, Yan; Mueller, Marion; Pfeil, Eva; Matthey, Michaela; Rieck, Sarah; Alenfelder, Judith; Koenig, Gabriele M.; Pfeifer, Alexander; Kostenis, Evi; Klinke, Anna; Fleischmann, Bernd K.; Wenzel, Daniela Share Save
Site-specific genetic and functional signatures of aortic endothelial cells at aneurysm predilection sites in healthy and AngII ApoE-/- mice Brueckner, Alexander; Brandtner, Adrian; Rieck, Sarah; Matthey, Michaela; Geisen, Caroline; Fels, Benedikt; Stei, Marta; Kusche-Vihrog, Kristina; Fleischmann, Bernd K.; Wenzel, Daniela Share Save
Imaging of Gαq Proteins in Mouse and Human Organs and Tissues Voss, Jan H.; Al-Hroub, Haneen; Gedschold, Robin; Dietrich, Jennifer M.; Gaffal, Evelyn; Toma, Marieta; Kehraus, Stefan; Koenig, Gabriele M.; Brust, Peter; Fleischmann, Bernd K.; Wenzel, Daniela; Deuther-Conrad, Winnie; Mueller, Christa E. Share Save
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A PI3Kγ mimetic peptide triggers CFTR gating, bronchodilation, and reduced inflammation in obstructive airway diseases Ghigo, Alessandra; Murabito, Alessandra; Sala, Valentina; Pisano, Anna Rita; Bertolini, Serena; Gianotti, Ambra; Caci, Emanuela; Montresor, Alessio; Premchandar, Aiswarya; Pirozzi, Flora; Ren, Kai; Della Sala, Angela; Mergiotti, Marco; Richter, Wito; de Poel, Eyleen; Matthey, Michaela; Caldrer, Sara; Cardone, Rosa A.; Civiletti, Federica; Costamagna, Andrea; Quinney, Nancy L.; Butnarasu, Cosmin; Visentin, Sonja; Ruggiero, Maria Rosaria; Baroni, Simona; Crich, Simonetta Geninatti; Ramel, Damien; Laffargue, Muriel; Tocchetti, Carlo G.; Levi, Renzo; Conti, Marco; Lu, Xiao-Yun; Melotti, Paola; Sorio, Claudio; De Rose, Virginia; Facchinetti, Fabrizio; Fanelli, Vito; Wenzel, Daniela; Fleischmann, Bernd K.; Mall, Marcus A.; Beekman, Jeffrey; Laudanna, Carlo; Gentzsch, Martina; Lukacs, Gergely L.; Pedemonte, Nicoletta; Hirsch, Emilio Share Save
Heterotrimeric G Protein Subunit Gαq Is a Master Switch for Gβγ-Mediated Calcium Mobilization by Gi-Coupled GPCRs Pfeil, Eva Marie; Brands, Julian; Merten, Nicole; Voegtle, Timo; Vescovo, Maddalena; Rick, Ulrike; Albrecht, Ina-Maria; Heycke, Nina; Kawakami, Kouki; Ono, Yuki; Kadji, Francois Marie Ngako; Hiratsuka, Suzune; Aoki, Junken; Haeberlein, Felix; Matthey, Michaela; Garg, Jaspal; Hennen, Stephanie; Jobin, Marie-Lise; Seier, Kerstin; Calebiro, Davide; Pfeifer, Alexander; Heinemann, Akos; Wenzel, Daniela; Koenig, Gabriele M.; Nieswandt, Bernhard; Fleischmann, Bernd K.; Inoue, Asuka; Simon, Katharina; Kostenis, Evi Share Save
Cell-permeable high-affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors Kuschak, Markus; Namasivayam, Vigneshwaran; Rafehi, Muhammad; Voss, Jan H.; Garg, Jaspal; Schlegel, Jonathan G.; Abdelrahman, Aliaa; Kehraus, Stefan; Reher, Raphael; Kueppers, Jim; Sylvester, Katharina; Hinz, Sonja; Matthey, Michaela; Wenzel, Daniela; Fleischmann, Bernd K.; Pfeifer, Alexander; Inoue, Asuka; Guetschow, Michael; Koenig, Gabriele M.; Mueller, Christa E. Share Save
A tissue-specific screen of ceramide expression in aged mice identifies ceramide synthase-1 and ceramide synthase-5 as potential regulators of fiber size and strength in skeletal muscle Tosetti, Bettina; Brodesser, Susanne; Brunn, Anna; Deckert, Martina; Blueher, Matthias; Doehner, Wolfram; Anker, Stefan D.; Wenzel, Daniela; Fleischmann, Bernd; Pongratz, Carola; Peters, Franziska; Utermoehlen, Olaf; Kroenke, Martin Share Save
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Targeted inhibition of Gq signaling induces airway relaxation in mouse models of asthma Matthey, Michaela; Roberts, Richard; Seidinger, Alexander; Simon, Annika; Schroeder, Ralf; Kuschak, Markus; Annala, Suvi; Koenig, Gabriele M.; Mueller, Christa E.; Hall, Ian P.; Kostenis, Evi; Fleischmann, Bernd K.; Wenzel, Daniela Share Save
The experimental power of FR900359 to study Gq-regulated biological processes Schrage, Ramona; Schmitz, Anna-Lena; Gaffal, Evelyn; Annala, Suvi; Kehraus, Stefan; Wenzel, Daniela; Buellesbach, Katrin M.; Bald, Tobias; Inoue, Asuka; Shinjo, Yuji; Galandrin, Segolene; Shridhar, Naveen; Hesse, Michael; Grundmann, Manuel; Merten, Nicole; Charpentier, Thomas H.; Martz, Matthew; Butcher, Adrian J.; Slodczyk, Tanja; Armando, Sylvain; Effern, Maike; Namkung, Yoon; Jenkins, Laura; Horn, Velten; Stoessel, Anne; Dargatz, Harald; Tietze, Daniel; Imhof, Diana; Gales, Celine; Drewke, Christel; Mueller, Christa E.; Hoelzel, Michael; Milligan, Graeme; Tobin, Andrew B.; Gomeza, Jesus; Dohlman, Henrik G.; Sondek, John; Harden, T. Kendall; Bouvier, Michel; Laporte, Stephane A.; Aoki, Junken; Fleischmann, Bernd K.; Mohr, Klaus; Koenig, Gabriele M.; Tueting, Thomas; Kostenis, Evi Share Save
The toxic effect of R350P mutant desmin in striated muscle of man and mouse Clemen, Christoph S.; Stoeckigt, Florian; Strucksberg, Karl-Heinz; Chevessier, Frederic; Winter, Lilli; Schuetz, Johanna; Bauer, Ralf; Thorweihe, Jose-Manuel; Wenzel, Daniela; Schloetzer-Schrehardt, Ursula; Rasche, Volker; Krsmanovic, Pavle; Katus, Hugo A.; Rottbauer, Wolfgang; Just, Steffen; Mueller, Oliver J.; Friedrich, Oliver; Meyer, Rainer; Herrmann, Harald; Schrickel, Jan Wilko; Schroeder, Rolf Share Save
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Chaperone-Assisted Selective Autophagy Is Essential for Muscle Maintenance Arndt, Verena; Dick, Nikolaus; Tawo, Riga; Dreiseidler, Michael; Wenzel, Daniela; Hesse, Michael; Fuerst, Dieter O.; Saftig, Paul; Saint, Robert; Fleischmann, Bernd K.; Hoch, Michael; Hoehfeld, Joerg Share Save
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