Not logged in A functional genomic approach to actionable gene fusions for precision oncology Li, Jun; Lu, Hengyu; Ng, Patrick Kwok-Shing; Pantazi, Angeliki; Ip, Carman Ka Man; Jeong, Kang Jin; Amador, Bianca; Tran, Richard; Tsang, Yiu Huen; Yang, Lixing; Song, Xingzhi; Dogruluk, Turgut; Ren, Xiaojia; Hadjipanayis, Angela; Bristow, Christopher A.; Lee, Semin; Kucherlapati, Melanie; Parfenov, Michael; Tang, Jiabin; Seth, Sahil; Mahadeshwar, Harshad S.; Mojumdar, Kamalika; Zeng, Dong; Zhang, Jianhua; Protopopov, Alexei; Seidman, Jonathan G.; Creighton, Chad J.; Lu, Yiling; Sahni, Nidhi; Shaw, Kenna R.; Meric-Bernstam, Funda; Futreal, Andrew; Chin, Lynda; Scott, Kenneth L.; Kucherlapati, Raju; Mills, Gordon B.; Liang, Han Share Save
Combinations with Allosteric SHP2 Inhibitor TNO155 to Block Receptor Tyrosine Kinase Signaling Liu, Chen; Lu, Hengyu; Wang, Hongyun; Loo, Alice; Zhang, Xiamei; Yang, Guizhi; Kowal, Colleen; Delach, Scott; Wang, Ye; Goldoni, Silvia; Hastings, William D.; Wong, Karrie; Gao, Hui; Meyer, Matthew J.; Moody, Susan E.; LaMarche, Matthew J.; Engelman, Jeffrey A.; Williams, Juliet A.; Hammerman, Peter S.; Abrams, Tinya J.; Mohseni, Morvarid; Caponigro, Giordano; Hao, Huai-Xiang Share Save
Combinations of SHP2 inhibitor to overcome RAS activation by receptor tyrosine kinases in response to ERK inhibition Hao, Huaixiang; Liu, Chen; Wang, Hongyun; Lu, Hengyu; Delach, Scott; LaMarche, Matthew; Engelman, Jeffrey; Hammerman, Peter; Caponigro, Giordano; Moody, Susan; Mohseni, Morvarid Share Save
Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression Tsang, Yiu Huen; Wang, Yumeng; Kong, Kathleen; Grzeskowiak, Caitlin; Zagorodna, Oksana; Dogruluk, Turgut; Lu, Hengyu; Villafane, Nicole; Bhavana, Venkata Hemanjani; Moreno, Daniela; Elsea, Sarah H.; Liang, Han; Mills, Gordon B.; Scott, Kenneth L. Share Save
Tumor Intrinsic Efficacy by SHP2 and RTK Inhibitors in KRAS-Mutant Cancers Hao, Huai-Xiang; Wang, Hongyun; Liu, Chen; Kovats, Steven; Velazquez, Roberto; Lu, Hengyu; Pant, Bhavesh; Shirley, Matthew; Meyer, Matthew J.; Pu, Minying; Lim, Joanne; Fleming, Michael; Alexander, Leigh Ann; Farsidjani, Ali; LaMarche, Matthew J.; Moody, Susan; Silver, Serena J.; Caponigro, Giordano; Stuart, Darrin D.; Abrams, Tinya J.; Hammerman, Peter S.; Williams, Juliet; Engelman, Jeffrey A.; Goldoni, Silvia; Mohseni, Morvarid Share Save
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SHP2 inhibition overcomes RTK-mediated pathway reactivation in KRAS mutant tumors treated with MEK inhibitors Lu, Hengyu; Liu, Chen; Velazquez, Roberto; Wang, Hongyun; Dunkl, Lukas M.; Kazic-Legueux, Malika; Haberkorn, Anne; Billy, Eric; Manchado, Eusebio; Brachmann, Saskia M.; Moody, Susan; Engelman, Jeffrey A.; Hammerman, Peter S.; Caponigro, Giordano; Mohseni, Morvarid; Hao, Huaixiang Share Save
SHP2 Inhibition Overcomes RTK-Mediated Pathway Reactivation in KRAS-Mutant Tumors Treated with MEK Inhibitors Lu, Hengyu; Liu, Chen; Velazquez, Roberto; Wang, Hongyun; Dunkl, Lukas Manuel; Kazic-Legueux, Malika; Haberkorn, Anne; Billy, Eric; Manchado, Eusebio; Brachmann, Saskia M.; Moody, Susan E.; Engelman, Jeffrey A.; Hammerman, Peter S.; Caponigro, Giordano; Mohseni, Morvarid; Hao, Huai-Xiang Share Save
In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer Grzeskowiak, Caitlin L.; Kundu, Samrat T.; Mo, Xiulei; Ivanov, Andrei A.; Zagorodna, Oksana; Lu, Hengyu; Chapple, Richard H.; Tsang, Yiu Huen; Moreno, Daniela; Mosqueda, Maribel; Eterovic, Karina; Fradette, Jared J.; Ahmad, Sumreen; Chen, Fengju; Chong, Zechen; Chen, Ken; Creighton, Chad J.; Fu, Haian; Mills, Gordon B.; Gibbons, Don L.; Scott, Kenneth L. Share Save
Simultaneous inhibition of SHP2 phosphatase at two allosteric sites Fodor, Michelle; Price, Edmund; Wang, Ping; Lu, Hengyu; Argintaru, Andreea; Chen, Zhouliang; Glick, Meir; Hao, Huai-Xiang; Kato, Mitsunori; Koenig, Robert; LaRochelle, Jonathan R.; Liu, Gang; McNeill, Eric; Majumdar, Dyuti; Nishiguchi, Gisele; Perez, Lawrence; Paris, Greg; Quinn, Christopher; Ramsey, Timothy; Sendzik, Martin; Shultz, Michael; Williams, Sarah; Stams, Travis; Blacklow, Stephen C.; LaMarche, Matthew J.; Acker, Michael G. Share Save
Dual Allosteric Inhibition of SHP2 Phosphatase Fodor, Michelle; Price, Edmund; Wang, Ping; Lu, Hengyu; Argintaru, Andreea; Chen, Zhouliang; Glick, Meir; Hao, Huai-Xiang; Kato, Mitsunori; Koenig, Robert; LaRochelle, Jonathan R.; Liu, Gang; McNeill, Eric; Majumdar, Dyuti; Nishiguchi, Gisele A.; Perez, Lawrence B.; Paris, Gregory; Quinn, Christopher M.; Ramsey, Timothy; Sendzik, Martin; Shultz, Michael David; Williams, Sarah L.; Stams, Travis; Blacklow, Stephen C.; Acker, Michael G.; LaMarche, Matthew J. Share Save
Engineering and Functional Characterization of Fusion Genes Identifies Novel Oncogenic Drivers of Cancer Lu, Hengyu; Villafane, Nicole; Dogruluk, Turgut; Grzeskowiak, Caitlin L.; Kong, Kathleen; Tsang, Yiu Huen; Zagorodna, Oksana; Pantazi, Angeliki; Yang, Lixing; Neill, Nicholas J.; Kim, Young Won; Creighton, Chad J.; Verhaak, Roel G.; Mills, Gordon B.; Park, Peter J.; Kucherlapati, Raju; Scott, Kenneth L. Share Save
Analyzing Somatic Genome Rearrangements in Human Cancers by Using Whole-Exome Sequencing Yang, Lixing; Lee, Mi-Sook; Lu, Hengyu; Oh, Doo-Yi; Kim, Yeon Jeong; Park, Donghyun; Park, Gahee; Ren, Xiaojia; Bristow, Christopher A.; Haseley, Psalm S.; Lee, Soohyun; Pantazi, Angeliki; Kucherlapati, Raju; Park, Woong-Yang; Scott, Kenneth L.; Choi, Yoon-La; Park, Peter J. Share Save
Functional annotation of rare gene aberration drivers of pancreatic cancer Tsang, Yiu Huen; Dogruluk, Turgut; Tedeschi, Philip M.; Wardwell-Ozgo, Joanna; Lu, Hengyu; Espitia, Maribel; Nair, Nikitha; Minelli, Rosalba; Chong, Zechen; Chen, Fengju; Chang, Qing Edward; Dennison, Jennifer B.; Dogruluk, Armel; Li, Min; Ying, Haoqiang; Bertino, Joseph R.; Gingras, Marie-Claude; Ittmann, Michael; Kerrigan, John; Chen, Ken; Creighton, Chad J.; Eterovic, Karina; Mills, Gordon B.; Scott, Kenneth L. Share Save
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RET Fusion as a Novel Driver of Medullary Thyroid Carcinoma Grubbs, Elizabeth G.; Ng, Patrick Kwok-Shing; Bui, Jacquelin; Busaidy, Naifa L.; Chen, Ken; Lee, Jeffrey E.; Lu, Xinyan; Lu, Hengyu; Meric-Bernstam, Funda; Mills, Gordon B.; Palmer, Gary; Perrier, Nancy D.; Scott, Kenneth L.; Shaw, Kenna R.; Waguespack, Steven G.; Williams, Michelle D.; Yelensky, Roman; Cote, Gilbert J. Share Save
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