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SaveShare Save Share Save Identification of NVP-TNKS656: The Use of Structure-Efficiency Relationships To Generate a Highly Potent, Selective, and Orally Active Tankyrase Inhibitor
Shultz, Michael D.; Cheung, Atwood K.; Kirby, Christina A.; Firestone, Brant; Fan, Jianmei; Chen, Christine Hiu-Tung; Chen, Zhouliang; Chin, Donovan N.; DiPietro, Lucian; Fazal, Aleem; Feng, Yun; Fortin, Pascal D.; Gould, Ty; Lagu, Bharat; Lei, Huangshu; Lenoir, Francois; Majumdar, Dyuti; Ochala, Etienne; Palermo, M. G.; Ly Pham; Pu, Minying; Smith, Troy; Stams, Travis; Tomlinson, Ronald C.; Toure, B. Barry; Visser, Michael; Wang, Run Ming; Waters, Nigel J.; Shao, Wenlin Share Save 1-Amino-4-benzylphthalazines as Orally Bioavailable Smoothened Antagonists with Antitumor ActivityMiller-Moslin, Karen; Peukert, Stefan; Jain, Rishi K.; McEwan, Michael A.; Karki, Rajesh; Llamas, Luis; Yusuff, Naeem; He, Feng; Li, Yanhong; Sun, Yingchuan; Dai, Miao; Perez, Lawrence; Michael, Walter; Sheng, Tao; Lei, Huangshu; Zhang, Rui; Williams, Juliet; Bourret, Aaron; Ramamurthy, Arun; Yuan, Jing; Guo, Ribo; Matsumoto, Melissa; Vattay, Anthony; Maniara, Wieslawa; Amaral, Adam; Dorsch, Marion; Kelleher, Joseph F., III Share Save Reversible Carboxamide-Mediated Internal Activation at C(6) of 2-Chloro-4-anilino-1H-pyrrolo[2,3-d]pyrimidinesChamberlain, Stanley D.; Gerding, Roseanne M.; Lei, Huangshu; Moorthy, Ganesh; Patnaik, Samarjit; Redman, Aniko M.; Stevens, Kirk L.; Wilson, Joseph W.; Yang, Bin; Shotwell, J. Brad Share Save Share Save 
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