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Inhibition of the chemokine receptors CXCR1 and CXCR2 synergizes with docetaxel for effective tumor control and remodeling of the immune microenvironment of HPV-negative head and neck cancer models Horn, Lucas A.; Lind, Hanne; Fousek, Kristen; Qin, Haiyan; Rajabian, Nika; Angstadt, Shantel; Hsiao-Sanchez, Nicole; Medina-Enriquez, Miriam M.; Kelly, Marcus D.; Allen, Clint T.; Hammoudeh, Sarah M.; Weigert, Roberto; Maeda, Dean Y.; Zebala, John A.; Palena, Claudia Share Save
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Remodeling the tumor microenvironment via blockade of LAIR-1 and TGF-β signaling enables PD-L1-mediated tumor eradication Horn, Lucas A.; Chariou, Paul L.; Gameiro, Sofia R.; Qin, Haiyan; Iida, Masafumi; Fousek, Kristen; Meyer, Thomas J.; Cam, Margaret; Flies, Dallas; Langermann, Solomon; Schlom, Jeffrey; Palena, Claudia Share Save
Phase 1 open-label trial of intravenous administration of MVA-BN-brachyury-TRICOM vaccine in patients with advanced cancer DeMaria, Peter J.; Lee-Wisdom, Katherine; Donahue, Renee N.; Madan, Ravi A.; Karzai, Fatima; Schwab, Angie; Palena, Claudia; Jochems, Caroline; Floudas, Charalampos; Strauss, Julius; Marte, Jennifer L.; Redman, Jason Mark; Dombi, Eva; Widemann, Brigitte; Korchin, Borys; Adams, Tatiana; Pico-Navarro, Cesar; Heery, Christopher; Schlom, Jeffrey; Gulley, James L.; Bilusic, Marijo Share Save
T Cell-Mediated Antitumor Immunity Cooperatively Induced By TGFβR1 Antagonism and Gemcitabine Counteracts Reformation of the Stromal Barrier in Pancreatic Cancer Li, Dandan; Schaub, Nicholas; Guerin, Theresa M.; Bapiro, Tashinga E.; Richards, Frances M.; Chen, Vicky; Talsania, Keyur; Kumar, Parimal; Gilbert, Debra J.; Schlomer, Jerome J.; Kim, Seong-Jin; Sorber, Rebecca; Teper, Yaroslav; Bautista, Wendy; Palena, Claudia; Ock, Chan-Young; Jodrell, Duncan, I; Pate, Nathan; Mehta, Monika; Zhao, Yongmei; Kozlov, Serguei; Rudloff, Udo Share Save
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Improving the Odds in Advanced Breast Cancer With Combination Immunotherapy: Stepwise Addition of Vaccine, Immune Checkpoint Inhibitor, Chemotherapy, and HDAC Inhibitor in Advanced Stage Breast Cancer Gatti-Mays, Margaret E.; Gameiro, Sofia R.; Ozawa, Yohei; Knudson, Karin M.; Hicks, Kristin C.; Palena, Claudia; Cordes, Lisa M.; Steinberg, Seth M.; Francis, Deneise; Karzai, Fatima; Lipkowitz, Stanley; Donahue, Renee N.; Jochems, Caroline; Schlom, Jeffrey; Gulley, James L. Share Save
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The Use of a Humanized NSG-β2m-/- Model for Investigation of Immune and Anti-tumor Effects Mediated by the Bifunctional Immunotherapeutic Bintrafusp Alfa Morillon, Y. Maurice, II; Smalley Rumfield, Claire; Pellom, Samuel T.; Sabzevari, Ariana; Roller, Nicholas T.; Horn, Lucas A.; Jochems, Caroline; Palena, Claudia; Greiner, John W.; Schlom, Jeffrey Share Save
Simultaneous inhibition of CXCR1/2, TGF-β, and PD-L1 remodels the tumor and its microenvironment to drive antitumor immunity Horn, Lucas A.; Riskin, Jeffrey; Hempel, Heidi A.; Fousek, Kristen; Lind, Hanne; Hamilton, Duane H.; McCampbell, Kristen K.; Maeda, Dean Y.; Zebala, John A.; Su, Zhen; Schlom, Jeffrey; Palena, Claudia Share Save
A phase Ib trial of sequential combinations of BN-brachyury, entinostat, ado-trastuzumab emtansine (T-DM1) and bintrafusp alfa (M7824) in advanced stage breast cancer (BrEAsT) Gatti-Mays, Margaret E.; Palena, Claudia; Gameiro, Sofia R.; Donahue, Renee N.; Jochems, Caroline; Steinberg, Seth; Lipkowitz, Stan; Zimmer, Alexandra; Francis, Deneise; Strauss, Julius; Sater, Houssein Abdul; Cordes, Lisa; Redman, Jason; Karzai, Fatima; Bilusic, Marijo; Madan, Ravi A.; Gulley, James L.; Schlom, Jeffrey Share Save
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Inhibiting myeloid-derived suppressor cell trafficking enhances T cell immunotherapy Sun, Lillian; Clavijo, Paul E.; Robbins, Yvette; Patel, Priya; Friedman, Jay; Greene, Sarah; Das, Rita; Silvin, Chris; Van Waes, Carter; Horn, Lucas A.; Schlom, Jeffrey; Palena, Claudia; Maeda, Dean; Zebala, John; Allen, Clint T. Share Save
In-situ diversification of immunity following vaccination targeting tumor neoepitopes; an integral component of combinatorial immunotherapy Lee, K. L.; Palena, C.; Lee, J.; Niazi, K.; Nguyen, A.; Benz, S. C.; Su, Z.; Rabizadeh, S.; Soon-Shiong, P.; Schlom, J.; Hamilton, D. H. Share Save
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