logo
CanyamAI summaries for academic research
language
MobileMobile
  • Phone FeatureWeChat Mini Program
EnglishEnglish
noticeNotice
BlogBlog
delete
arrow
Back
A

Alexander I. Sobolevsky

columbia university

43H-index
207Paper Count
7.1KCitation Count
Published Papers 63
Publication Date
logo
Design, synthesis and structural mechanism of action of TRPV1 agonist MSP20 with long-lasting analgesic effect
errNature Communications
IF15.7
err2026-07-06
err0
errOAAI
errArthur Neuberger; Isabella Romeo; Francesca Aiello; Alexey Alekseev; Samuele Maramai; Federica Pessina; Chiara Vagaggini; Federica Poggialini; Elena Dreassi; Maria Frosini; Aniello Schiano Moriello; Luciano De Petrocellis; Andrea Maria Morace; Carmela Belardo; Michela Perrone; Roozbe Bonsale; Livio Luongo; Sabatino Maione; Irina A. Talyzina; Stefano Alcaro; Anna Artese; Antonella Brizzi; Alexander I. Sobolevsky
errShare
errSave
Structural diversity of heat-sensing channel TRPV3 with Olmsted syndrome mutations
errNature Communications
IF15.7
err2026-06-20
err0
errOAAI
errJeffrey Khau; Rutambhara Purohit; Kirill D. Nadezhdin; Irina A. Talyzina; Alexander I. Sobolevsky
errShare
errSave
Open-channel block of human TRPV6 by polyamine spermine
errNature Communications
IF15.7
err2026-05-27
err0
errOAAI
errArthur Neuberger; Irina I. Veretenenko; Alexey Shalygin; Yury A. Trofimov; Thomas Gudermann; Vladimir Chubanov; Roman G. Efremov; Alexander I. Sobolevsky
errShare
errSave
Auxiliary subunits reshape structural asymmetry and functional plasticity in heterotetrameric GluA1/A2 AMPA receptor core
errNature Communications
IF15.7
err2026-03-28
err0
errOAAI
errLaura Y. Yen; Thomas P. Newton; Maria V. Yelshanskaya; Muhammed Aktolun; Shanti Pal Gangwar; Rasmus P. Clausen; Maria G. Kurnikova; Alexander I. Sobolevsky
errShare
errSave
Claudin 24—A novel enhancer of AMPA receptor fidelity
errScience Advances
IF12.5
err2026-03-06
err0
errOAAI
errTobias Strasdeit; Ehsan Amin; Sebastian Obst; Barbara Biermann; Thomas P. Newton; Simon Chris Kösters; Marten Schouwink; Sergey Fedotov; Javeria Shaukat; Subhrajit Bhattacharya; Muhammad Aslam; Max Anstötz; Faik Nadi Okka; Oscar Gabriel Sevillano Quispe; Pascal Bouvain; Julia Vedyashkin; Alexander I. Sobolevsky; Stephen F. Traynelis; Jakob von Engelhardt; Nadine Erlenhardt; Michael Hollmann; Nikolaj Klöcker
errShare
errSave
Endothelium glutamate receptors in brain pathology
errFrontiers in Pharmacology
IF4.8
err2025-12-04
err0
errOAAI
errSergey V. Pirozhkov; Marina N. Vukolova; Varvara V. Bulgakova; Yulia A. Lutokhina; Sergey B. Bolevich; Alexander I. Sobolevsky; Maria V. Yelshanskaya
errShare
errSave
The nucleobase guanine at the 3’-terminus of oligonucleotide RGLS4326 drives off-target AMPAR inhibition and CNS toxicity
errNature Communications
IF15.7
err2025-11-28
err0
errOAAI
errTania Valencia; Laura Y. Yen; Cindy Berman; Thomas Vincent; Scott Davis; Francesca Varrone; Jianfeng Huang; Jessica Mastroianni; Morgan Carlson; Tate Owen; Amin Kamel; Denis Drygin; Garth A. Kinberger; Shanti Pal Gangwar; Maria V. Yelshanskaya; John Ridley; Robert Kirby; Jesus Alvarez; Ronak Lakhia; Vishal Patel; Alexander I. Sobolevsky; Edmund C. Lee
errShare
errSave
The locking mechanism of human TRPV6 inhibition by intracellular magnesium
errNature Communications
IF15.7
err2025-11-06
err0
errOAAI
errArthur Neuberger; Alexey Shalygin; Irina I. Veretenenko; Yury A. Trofimov; Thomas Gudermann; Vladimir Chubanov; Roman G. Efremov; Alexander I. Sobolevsky
errShare
errSave
Structure and gating of kainate receptors
errFrontiers in Pharmacology
IF4.8
err2025-10-20
err0
errOAAI
errShanti P. Gangwar; Maria V. Yelshanskaya; Laura Y. Yen; Thomas P. Newton; Alexander I. Sobolevsky
errShare
errSave
Activation of kainate receptor GluK2–Neto2 complex
errNature Structural & Molecular Biology
IF10.1
err2025-08-22
err0
errOAAI
errShanti Pal Gangwar; Maria V. Yelshanskaya; Laura Y. Yen; Thomas P. Newton; Alexander I. Sobolevsky
errShare
errSave
Forty sites of TRP channel regulation
errCURRENT OPINION IN CHEMICAL BIOLOGY
IF6.1
err2025-02-01
err0
errOAAI
errTalyzina, Irina A.; Nadezhdin, Kirill D.; Sobolevsky, Alexander I.
errShare
errSave
Trapping of spermine, Kukoamine A, and polyamine toxin blockers in GluK2 kainate receptor channels
errNATURE COMMUNICATIONS
IF15.7
err2024-11-26
err0
errOAAI
errGangwar, Shanti Pal; Yelshanskaya, Maria V.; Aktolun, Muhammed; Yen, Laura Y.; Newton, Thomas P.; Stromgaard, Kristian; Kurnikova, Maria G.; Sobolevsky, Alexander I.
errShare
errSave
Dynamic molecular portraits of ion-conducting pores characterize functional states of TRPV channels
errCOMMUNICATIONS CHEMISTRY
IF6.2
err2024-06-01
err3
errOAAI
errTrofimov, Yury A.; Krylov, Nikolay A.; Minakov, Alexander S.; Nadezhdin, Kirill D.; Neuberger, Arthur; Sobolevsky, Alexander I.; Efremov, Roman G.
errShare
errSave
TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site
errSCIENCE ADVANCES
IF12.5
err2024-05-03
err5
errOAAI
errNadezhdin, Kirill D.; Neuberger, Arthur; Khosrof, Lena S.; Talyzina, Irina A.; Khau, Jeffrey; Yelshanskaya, Maria V.; Sobolevsky, Alexander I.
errShare
errSave
Dissecting the biophysics and biology of intrinsically disordered proteins
errTRENDS IN BIOCHEMICAL SCIENCES
IF11
err2024-02-01
err1
PREAI
errBanerjee, Priya R.; Holehouse, Alex S.; Kriwacki, Richard; Robustelli, Paul; Jiang, Hao; Sobolevsky, Alexander I.; Hurley, Jennifer M.; Mendell, Joshua T.
errShare
errSave
Pentameric TRPV3: An artifact or a clue to channel function?
errCELL CALCIUM
IF4
err2023-12-01
err3
errOAAI
errNeuberger, Arthur; Sobolevsky, Alexander I.
errShare
errSave
Molecular pharmacology of the onco-TRP channel TRPV6
errCHANNELS
IF3.2
err2023-10-15
err3
errOAAI
errNeuberger, Arthur; Sobolevsky, Alexander I.
errShare
errSave
Modulation of GluA2-γ5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2023-08-31
err7
errOAAI
errGangwar, Shanti Pal; Yen, Laura Y.; Yelshanskaya, Maria V.; Korman, Aryeh; Jones, Drew R.; Sobolevsky, Alexander I.
errShare
errSave
Molecular pathway and structural mechanism of human oncochannel TRPV6 inhibition by the phytocannabinoid tetrahydrocannabivarin
errNATURE COMMUNICATIONS
IF15.7
err2023-08-02
err5
errOAAI
errNeuberger, Arthur; Trofimov, Yury A.; Yelshanskaya, Maria V.; Khau, Jeffrey; Nadezhdin, Kirill D.; Khosrof, Lena S.; Krylov, Nikolay A.; Efremov, Roman G.; Sobolevsky, Alexander I.
errShare
errSave
Structure of human TRPV4 in complex with GTPase RhoA
errNATURE COMMUNICATIONS
IF15.7
err2023-06-23
err21
errOAAI
errNadezhdin, Kirill D.; Talyzina, Irina A.; Parthasarathy, Aravind; Neuberger, Arthur; Zhang, David X.; Sobolevsky, Alexander I.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
J
Joachim Frank
H-index: 108 · Papers: 856
M
Matthias A. Hediger
H-index: 100 · Papers: 363
D
Daniel Choquet
H-index: 88 · Papers: 273
E
Eric Gouaux
H-index: 85 · Papers: 1.2K
S
Stephen F. Traynelis
H-index: 85 · Papers: 336
View more